scholarly journals Plasma Fibrinogen and Fibrin Degradation Product (FDP) in Preeclampsia

2019 ◽  
Vol 31 (1) ◽  
pp. 36-38
Author(s):  
Sharmin Sultana ◽  
Susmita Nargis ◽  
Heera Lal Roy ◽  
Qazi Shamima Akhter ◽  
Rukhsana Afroz
Keyword(s):  
Degradation Product ◽  
Cross Sectional Study ◽  
Bleeding Complications ◽  
Control Group ◽  
Fibrin Degradation Product ◽  
Cross Sectional ◽  
Medical College ◽  
Medicine Today ◽  
Coagulation Analyzer ◽  
Sensitive Marker

Introduction: Hypercoagulable state is seen in preeclampsia which acts as a risk factor for thromboembolism & DIC. Altered coagulation indices (serum Fibrinogen & FDP) have been reported in patients with preeclampsia and have been suggested as a sensitive marker for detection of bleeding complications. This study was carried out to compare the coagulation indices in preeclamptic women. Materials & Methods: This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College (DMC), Dhaka from January to December 2014. Total 100 women aged 18 – 40 years were selected from the department of Obstetrics & Gynaecology of DMCH, Dhaka for this study. Among them 50 were preeclamptic and age matched 50 healthy nonpregnant women were considered as control group. Fibrinogen & Fibrin Degradation Product (FDP) were analyzed on automated coagulation analyzer. Result: In this study, serum Fibrinogen & FDP were significantly higher in preeclamptic than those of healthy women. Moreover, 100% & 64% preeclamptic patient had raised serum Fibrinogen & FDP respectively. Conclusion: From this study it can be concluded that serum Fibrinogen & FDP are directly related with preeclampsia. Medicine Today 2019 Vol.31(1): 36-38

scholarly journals Osteoporosis in Surgical Menopause

1970 ◽  
Vol 6 (1) ◽  
pp. 39-44 ◽  
Author(s):  
Farhana Kabir ◽  
Nasim Jahan ◽  
Nayma Sultana
Keyword(s):  
Cross Sectional Study ◽  
Control Group ◽  
Mineral Density ◽  
Cross Sectional ◽  
Medical College ◽  
T Score ◽  
Estrogen Level ◽  
Menopausal Women ◽  
Microparticle Enzyme Immunoassay ◽  
Group B

Background: Osteoporosis in both surgical and natural menopausal women are common health hazards all over the world. And the surgical menopausal women may have the greater chance of this disorder than those of natural menopausal women. Objective: To observe osteoporotic changes in both surgical and natural menopausal women in Bangladesh. Method: This Cross sectional study was carried out in the Department of Physiology, Sir Salimullah Medical College, Dhaka between 1st January 2010 to 31st December 2010. A total number of 60 female subjects were included in this study. Among them 30 surgical menopausal women age ranged from 45-55 years were included in the study group (Group B) and 30 natural menopausal women age ranged from 50-60 years were taken as control (Group A). All the menopausal women were selected from Out Patient Department (OPD) of Gynaecology and Obstetrics, Sir Salimullah Medical College and Mitford Hospital. Estimation of serum estrogen level by microparticle enzyme immunoassay (MEIA) method and T- score was obtained by Dual energy X-ray absorptiometry of both natural and surgical menopausal women were done. The statistical analysis was done by using appropriate method as applicable. Results: In this study T- score of both spinal and femoral neck bone were significantly (p<0.001) lower in surgical menopausal women than those of natural menopausal women. Again, mean serum estrogen level was significantly (p<0.001) lower in surgical menopausal women than that of natural menopausal women. Conclusion: The present study revealed that surgical menopausal women have greater chance of osteoporosis than those of natural menopausal women. Key words: Menopause; Bone mineral density; Osteoporosis.   DOI: http://dx.doi.org/10.3329/jbsp.v6i1.8083 J Bangladesh Soc Physiol. 2011 June; 6(1): 39-44

scholarly journals SOCIO-DEMOGRAPHIC PROFILE IN PREECLAMPSIA

2020 ◽  
Vol 4 (12) ◽  
Author(s):  
Kumari Amrita ◽  
Verma Asha ◽  
Bajiya Monika ◽  
Gurjar Anil ◽  
Muhal Poonam
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Cross Sectional Study ◽  
Control Group ◽  
Cross Sectional ◽  
Medical College ◽  
Maternal Morbidity And Mortality ◽  
The Mean ◽  
Cardiac System ◽  
New Onset

Background: Pre-eclampsia is a complex multisystem condition. It affects 3-5% of all prenancies.It is defined as new onset hypertension after twenty weeks of pregnancy plus involvement of at least one organ system-renal, hepatic, neurological, hematological, pulmonary or cardiac system or as utero-placental dysfunction Methods: This was a hospital based comparative analytical cross sectional study carried out over 2 years period from may 2019 in the Department of Obstetrics and Gynecology, SMS Medical College and attached hospitals, Jaipur. Results:  The mean age of cases (27.36 ± 3.66 years) was higher than the controls (23.43 ± 3.23 years). There was not much difference in the distribution of subjects according to residence. In the study group 26 (57.78%) women belonged to urban areas and 19 (42.22%) belonged to rural areas whereas in the control group, 26 (62.22%) women belonged to rural areas and 17 (37.78%) belonged to urban areas. There were more primigravida in pre eclamptic group compared to the control group. Conclusion: Identification of risk factor in the antenatal period helps in early detection of women who are at high risk of developing pre-eclampsia in order to reduce maternal morbidity and mortality. Keywords: Preclampsia, Age, Gravida

scholarly journals Effect of Gestational Age and Nutrition on Transplacental Transfer of Measles Antibody

1970 ◽  
Vol 22 (1) ◽  
pp. 1-5
Author(s):  
Saima Kumar ◽  
Osul Ahmed Chowdhury ◽  
Md Murshed ◽  
Rabiul Hasan
Keyword(s):  
Gestational Age ◽  
Venous Blood ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Transplacental Transfer ◽  
Medical College ◽  
Good Nutrition ◽  
Medicine Today ◽  
Antibody Levels

A cross sectional study was done to find out the role of gestational age and nutrition on transplacental tranfer of measles antibody. The study was made on pregnant women admitted for delivery from July 2008 to June 2009 in Sylhet M A G Osmani Medical College Hospitals. Sample of venous blood of 94 pregnant mother and 94 cord blood of their newborn babies were collected and processed as per work schedule. Samples were tested by quantitative ELISA method for measles antibody. It was observed that baby of full term mother and good nutrition had higher antibody levels. Protein and haemoglobin level was taken as nutritional indicator. Keywords: Measles IgG; Transplacental transfer; Nutrition; Gestational age. DOI: 10.3329/medtoday.v22i1.5596 Medicine Today Vol.22(1) 2010. 1-5

EVALUATION OF DIASTOLIC DYSFUNCTION IN CHILDREN WITH ASYMPTOMATIC BETA- THALASSEMIA MAJOR AN

2021 ◽  
pp. 5-7
Author(s):  
Radhabinod Pal ◽  
Akshay Devendra Dhore ◽  
Biswarup Sarkar
Keyword(s):  
Diastolic Dysfunction ◽  
Diastolic Function ◽  
Ferritin Level ◽  
Normal Subjects ◽  
Thalassemia Major ◽  
Cross Sectional Study ◽  
Beta Thalassemia ◽  
Control Group ◽  
Cross Sectional ◽  
Medical College

This was an observational cross-sectional study of 96 Patients at R.G Kar Medical College and Hospital, st Kolkata. with diagnosis of β Thalassemia major children aged between 2-12 years between 1 March, th 2016 to 28 February, 2017. A control group of 100 normal subjects matched according to age and sex, with the cases were also studied. Patients who full the inclusion and exclusion criteria were enrolled for the study after getting written informed consent. Echocardiography study was done of all the patients for assesment of diastolic function and determined whether it has any correlation with serum ferritin level in asymptomatic β Thalassemia major. It showed 66.67% of children were suffering from diastolic dysfunction, most of them were in grade 1 diastolic dysfunction followed by grade 3 diastolic dysfunction. The grade of diastolic function was correlated to the serum level of ferritin

scholarly journals Association of Obesity with Hypertension in Adult Female

2017 ◽  
Vol 28 (1) ◽  
pp. 28-33
Author(s):  
Nahid Yeasmin ◽  
Sayeeda Mahmuda ◽  
Shamima Akther ◽  
Khadija Begum ◽  
Masud Salehin ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Waist Circumference ◽  
Body Mass ◽  
Medical Problem ◽  
Cross Sectional Study ◽  
Control Group ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Female Subjects

Background: Incidence of hypertension in female is increasing throughout the world, leading to life threatening medical problem like cardiovascular diseases, stroke. An association between hypertension and obesity has been identified.Objectives : The study was carried out to observe the association of obesity with hypertension in adult female.Methods : This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka, during the period of January 2011 to December 2011. A total number of one hundred female subjects were selected with age ranging from30 to50 years. Among them 50 hypertensive female subjects were included from out-patient department of Medicine, Dhaka medical college Hospital, Dhaka as study group(B) and 50 apparently healthy female were taken as control group(A) for comparison Waist circumference(WC) was measured and body mass index (BMI) was calculated in both groups. Data was analyzed by Unpaired Student’s ‘t’ test and Pearson’s correlation co-efficient (r) test as applicable.Results: The value of waist circumference was higher in hypertensive subjects than those of nonhypertensive female and result was statistically significant. Body mass index value was significantly (p<0.001) higher in hypertensive subjects in comparison to those of non-hypertensive subjects. In hypertensive subjects waist circumference and body mass index values were higher and showed significant positive correlation with systolic and diastolic blood pressure. Conclusion: Present study revealed that hypertension has positive and significant relationship with waist circumference and body mass index.Bangladesh J Medicine Jan 2017; 28(1) : 28-33

scholarly journals RHEUMATOID ARTHRITIS;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
Khadija Kiran ◽  
Uzma Jamil ◽  
Amtul Huda Sobhi ◽  
Zuhair Bhatti
Keyword(s):  
Rheumatoid Arthritis ◽  
Oxidative Stress ◽  
Cross Sectional Study ◽  
Categorical Variables ◽  
Control Group ◽  
P Value ◽  
Continuous Variables ◽  
Healthy Individuals ◽  
Cross Sectional ◽  
Medical College

Objectives: Objective of our study is to measure the concentration and role of Malondialdehydein determining the oxidative stress in rheumatoid arthritis patients in comparison with healthy individuals. Study Design: Cross sectional study. Setting: Department of physiology Gujranwala Medical College and Shalamar Medical College, Lahore. Period: From October 2016 to October 2017. Methodology: 180 patients of age 49 to 70 years of either gender. The approval for conducting experimental study was taken from ethical committee and consent information was taken from the patient on prescribed Performa. Data was analyzed on SPSS Version 23 related to study. Continuous variables were presented as mean and standard deviation like age and serum MDA concentration. Categorical variables were presented as numbers and percentages like gender. Post operative chi square test was applied and p- value less than or equal to 0.05 was considered as significant. Results: Total 180 person (n=180) of either genderwere included in this study. The study group was divided into two equal groups. Group A (RA group) consists of 90 patients (n=90) based on clinically and laboratory based criteria while group B (control group) consists of 90 (n=90) normal healthy individuals. The serum MDA levels in the RA patients were 3.97±1.03 nmoles/ml and it was 1.59±0.32 n moles/ml in control patients. The difference was statistically significant (t=20.87, p=0.001). Conclusion: The observations of our study showed statistically significant raised serum Malondialdehyde level as compared to control group which shows that raised serum MDA is an indicator of oxidative stress in rheumatoid arthritis patients.  

scholarly journals Early Neonatal Outcome of Clinically Diagnosed Fetal Distress in Low Resource Areas

2021 ◽  
Vol 33 (2) ◽  
pp. 152-155
Author(s):  
Arifa Akhter ◽  
Asma Begum ◽  
Nadira Sultana ◽  
Shampa Saha ◽  
Mubina Nuzhat Chowdhury ◽  
...  
Keyword(s):  
Apgar Score ◽  
Neonatal Outcome ◽  
Active Phase ◽  
Fetal Distress ◽  
Cross Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Nicu Admission ◽  
Medicine Today

Introduction: Fetal distress is a high risk obstetric situation associated with increased perinatal morbidity and mortality. It is also a major contributor to operative interventions in the majority hospitals of developing countries. The objective of this study was to observe clinically diagnosed fetal distress and early neonatal outcome after delivery. Materials and Methods: This hospital based cross-sectional study was carried out in Department of Obstetrics and Gynecology at Bashundhara Addin Medical College Hospital, Keraniganj during the period of January to December 2019. 212 women in active phase of labor at term pregnancy who met the inclusion and exclusion criteria were enrolled. Fetal distress was diagnosed by abnormal FHR and /or presence of meconium in amniotic fluid after rupture of membrane. Neonatal outcome was assesss by 1st & 5th mins Apgar Scores after delivery, babies requiring immediate resuscitation and admission to neonatal care unit & recorded. Result: Among fetal distress 11.32% babies had Apgar score <7 as compared to babies without fetal distress that had 5.66% apgar score <7 at 5th minutes(p<0.05). 28.3% fetal distressed born babies required NICU admission rather than only 9.44% of without fetal distress. Conclusion: This study shows relative adverse neonatal outcome for fetal distressed babies than without distress. Medicine Today 2021 Vol.33(2): 152-155

scholarly journals Prediction of Perineal Tear During Childbirth by the Assessment of Striae Gravidarum Score

2019 ◽  
Vol 31 (2) ◽  
pp. 64-67
Author(s):  
Mahbuba Akhter Banu ◽  
SF Nargis ◽  
Mohammad Mizanoor Rahman ◽  
Md Mohim Ibn Sina ◽  
Murshida Pervin ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Vaginal Birth ◽  
Tissue Elasticity ◽  
Perineal Tear ◽  
Cross Sectional ◽  
Medical College ◽  
Lower Segment Caesarean Section ◽  
Medicine Today ◽  
Striae Gravidarum ◽  
Weight Gain During Pregnancy

Introduction: Perineal tear (PT) is the most frequently occurring injury during vaginal birth. Striae gravidarum (SG) is a reflecting marker of connective tissue elasticity. This study aimed to assess SG score and to predict the likelihood of PT during childbirth. Materials & Methods: This was a cross-sectional study done at Sir Salimullah Medical College & Mitford Hospital. Initially, all pregnant women admitted for vaginal delivery were enrolled but who subsequently needed lower segment caesarean section were excluded. Finally, 189 patients who gave vaginal birth were included. SG score was assessed using the Atwal numerical scoring system. The association was examined between PT as the outcome measure, defined by tears or lacerations and the total striae score (TSS) obtained at abdomen, hips, buttocks and breasts. Results: More than half of study patients developed PT. Majority belonged to moderate striae group. Significant correlation was found between PT and TSS. Moderate and severe striae had significantly increased prevalence of PT as compared to mild striae (43.4% vs. 11.6%). Patients who were given episiotomy in moderate and severe striae group had less PT. Weight gain during pregnancy and TSS were significantly associated with a higher incidence of PT. Conclusion: A woman’s SG score in general is a useful clinical predictor of the risk for PT during childbirth. Selective episiotomy in patients with moderate and severe striae can reduce the incidence of PT. SG score can be used as a simple and noninvasive tool by all categories of health personnel to better define women at risk for PT. Medicine Today 2019 Vol.31(2): 64-67

Side Effects of Chemotherapy and Cancer Treatment in Tertiary Care Teaching Hospital

2016 ◽  
Vol 2 (1) ◽  
pp. 62-78
Author(s):  
. Hemraj ◽  
Raj Kumar ◽  
Sourabh Kosey ◽  
Amit Sharma ◽  
Nalini Negi
Keyword(s):  
Side Effects ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Informational Needs ◽  
Cross Sectional ◽  
Clinical Pharmacists ◽  
Medical College ◽  
Related Information ◽  
The Common ◽  
Chemotherapy Patients

To determine the most common physical side effects experienced by local chemotherapy patients. Their perceptions of these side effects and informational needs from clinical pharmacists were also evaluated. This was a single center, observational cross-sectional study conducted at department of General Surgery, Guru Gobind Singh Medical College and Hospital, Faridkot, Punjab. A face to face interview was conducted. Information collected included chemotherapy related side effects after last chemotherapy experience, the most worrisome side effects, overlooked by healthcare professionals and the preferred method, amount and source of receiving related information. In this study, hundred patients were enrolled out of them 48 were male and 52 were female. When differential calculations was done, common side effects or adverse effects of chemotherapy in the patients of breast, lung cancer, Ovarian Cancer, Colon cancer, Prostate cancer, Lymphoma Cancer, Cervix cancer where there is much irregular medicine intake 57.4% may be due to common problem of joint pain reported by all the patients under study, with the consecutive problem of nausea and vomiting. The high prevalence of chemotherapy related side effects among local patients is a major concern and findings of their perceptions and informational needs may serve as a valuable guide for clinical pharmacists and physicians to help in side effect management. This study shows the common problems reported by the patients when they are suffering from cancer condition, according to their incidence perceptions as experienced by the patient, this will allow the physician and clinical pharmacist to effectively counsel and manage the common symptoms as reported prior to its occurrence in the patient, so that withdrawal can be checked.

DYSLIPIDEMIA IN THYROID DISORDERS

2020 ◽  
Vol 4 (7) ◽  
Author(s):  
Kashish Narula ◽  
Narendra Kumar Dara ◽  
Shyam Lal Meena
Keyword(s):  
Lipid Metabolism ◽  
Thyroid Dysfunction ◽  
Cross Sectional Study ◽  
Control Group ◽  
Thyroid Disorders ◽  
Cross Sectional ◽  
Carbohydrate And Lipid Metabolism ◽  
History Of ◽  
Thyroid Profile ◽  
Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

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