scholarly journals Sectional matrix system in reconstruction of proximal contact in class ii resin restoration

2021 ◽  
Vol 11 (2) ◽  
pp. 16-19
Author(s):  
Norun Nahar ◽  
AKM Bashar ◽  
Md Abdul Gafur ◽  
Didarul Haque Jeorge
Keyword(s):  
Composite Resin ◽  
Reference Group ◽  
Class Ii ◽  
Contact Points ◽  
Molar Teeth ◽  
Group A ◽  
Composite Resin Restoration ◽  
Bonferroni Test ◽  
Group B ◽  
Matrix Band

Background: Clinicians always faces some challenges to reconstruct proper proximal contact while restoring class-II cavity with composite resin due to its viscosity, elastic property and polymerization shrinkage. It has been claimed that use of sectional pre-contoured matrix band with separation ring will produce more reliable result for reconstruction of optimal proximal contact in class II composite resin restoration. Purpose: To evaluate the efficacy of sectional pre-contoured matrix band with separation ring for reconstruction of optimal proximal contact in class II resin composite restoration. Methodology:  One Nissin manikin model having the facility of placing and screwing all upper and lower sets of artificial human teeth and sixty-two (62) artificial human mandibular permanent 1st molar teeth were collected. These 62 artificial human mandibular permanent 1st molars were randomly assigned in two groups (A & B) having 31 teeth in each. Standardized class II MO (mesio-occlusal) cavity were prepared on total 31 artificial 1st molar in group A. The 2nd premolar in the manikin model was replaced by metal cast duplicate and permanently fixed into the socket. All the Thirty-one (31) 1st molar teeth in group A, having Prepared class II cavity in each, were replaced one by another in the manikin distal to cast duplicated 2nd premolar and restored with composite resin by using sectional pre-contoured matrix band with separation ring and another 31 uninstrumented intact artificial 1st molars were include in group B as a reference group. After completion of restoration, newly developed proximal contact points were measured by using universal testing machine one after another. Same were also done in intact reference Group B. Measurement was done to assess the position of contact point, contact tightness and contact area of Group A and Group B on the same typodont. The results were analyzed statistically with post hoc Bonferroni test (P<0.05). Result: Teeth restored with sectional pre-contoured matrix with separation ring (group A) provided the tighter contact and broadened area of contact where all the contact points were placed  more occlusally compared to that of the intact un-instrumented reference teeth (group B).Statistically significant differences (P<0.05) were produced in all the three parameters with each other. Conclusion: Teeth restored with sectional pre-contoured matrix band with separation ring failed to reconstruct the optimal proximal contact in class-II composite resin restoration in comparison to intact uninstrumented reference tooth. Update Dent. Coll. j: 2021; 11(2): 16-19

scholarly journals Microleakage of Class I and II Composite Resin Restorations Using a Sonic-resin Placement System

2015 ◽  
Vol 40 (6) ◽  
pp. 653-661 ◽  
Author(s):  
J Kalmowicz ◽  
JG Phebus ◽  
BM Owens ◽  
WW Johnson ◽  
GT King
Keyword(s):  
Composite Resin ◽  
Acrylic Resin ◽  
Adhesive System ◽  
Class Ii ◽  
Class I ◽  
Blue Dye ◽  
Group A ◽  
Composite Resin Restorations ◽  
Level Of Significance ◽  
Group B

SUMMARYObjectivesTo determine microleakage of posterior Class I and II restorations using the SonicFill composite resin system.Methods and MaterialsEighty previously extracted third molars were randomly assigned to four preparation/restoration groups (n=20): Group A: Class I preparations restored with SonicFill system/bulk fill; Group B: Class II preparations restored with SonicFill system/bulk fill; Group C: Class I preparations restored with Herculite Ultra composite resin/incremental technique; and Group D: Class II preparations restored with Herculite Ultra composite resin/incremental technique. Class I preparations were approximately 3.0 mm in width buccolingually and 3.0 mm in depth. Class II preparations were approximately 3.0 mm in width buccolingually, 1.5 mm in axial depth, and 4.0 mm in gingival depth. In all groups, the enamel and dentin surfaces were conditioned with Kerr 37.5% phosphoric acid, followed by application of Optibond Solo Plus adhesive system. Following restoration, the specimens were thermocycled, immersed in methylene blue dye, and embedded in acrylic resin. Specimen blocks were sectioned in the mesiodistal direction, with marginal dye penetration (microleakage) examined using a 20× binocular microscope. Class I and II restoration microleakage was scored separately using a 0-3 ordinal ranking system. Statistical analyses were conducted using nonparametric testing at the p &lt; 0.05 level of significance.ResultsSignificantly less microleakage was associated with both Class I restorative groups (A and C), SonicFill bulk fill and Herculite Ultra incremental fill, compared to the Class II restorative groups (B and D), SonicFill/bulk fill and Herculite Ultra/incremental fill.ConclusionsAccording to the results of this study, the materials (SonicFill vs Herculite Ultra), C-factors, and insertion techniques (bulk vs incremental) did not appear to be significant influences with regard to marginal microleakage; however, the type of preparation cavity (Class I vs Class II) and the subsequent bonding surface (enamel vs dentin [cementum]) proved to be significant factors.

scholarly journals Study of microleakage in dental enamel using nanofillers composite resin restoration with total-etch and self-etch adhesive

2021 ◽  
Vol 5 (1) ◽  
pp. 12-18
Author(s):  
Iin Sundari ◽  
Viona Diansari ◽  
Niska Darlianti
Keyword(s):  
Composite Resin ◽  
Average Distance ◽  
Dental Enamel ◽  
Single Bond ◽  
Fifth Generation ◽  
Nail Polish ◽  
Group A ◽  
Composite Resin Restoration ◽  
Group B ◽  
Self Etch

Microleakage is a poor marginal adaptation of the restoration, often found between cavity and restoration material. One of the reasons is the shrinkage during the composite resin during polymerization, causing the restoration’s adaption disturbed. Application of adhesive material on the cavity affects microleakage at the margin restoration and increases the adaptation between cavity and restoration material. This research aims to determine microleakage in dental enamel using nanofiller composite resin restoration with fifth-generation total-etch adhesive and eight-generation self-etch adhesive. This research used 16 specimens premolars, which were prepared cavity Class I G.V. Black and divided into two groups (group A and B). Group A used nanofiller composite resin FiltekTM Z350 + fifth-generation total-etch Adper Single Bond 2 (n=8), group B used nanofiller composite resin Filtek TM  Z350 + eight-generation self-etch Universal Single Bond Adper (n=8). The specimen isolated  using nail polish except in the work area.,then immersed in methylene blue 1% at 25°C (for 24 hours). After that, all specimens were washed and cut longitudinally. The results were observed using a Stereomicroscope and Scanning Electron Microscope (SEM). The observation’s results showed that the amount number of microleakage in group A (75%) less than in group B (100%), while the non-parametric statistic test using the Mann Whitney showed no significant differences (p0.143). Based on SEM images, the average distance between enamel and composite resin with total-etch adhesive was 1.40 ± 0.007µm, and 1.84 ± 0.509 µm for resin composite with self-etch adhesive. This research concluded that microleakage using nanofiller composite with the fifth-generation total-etch adhesive was smaller than nanofiller composite resin with the eighth -generation self-etch adhesive.KEYWORDS: Adhesive system, nanofillers composite resin, microleakage, enamel

scholarly journals Scanning Electron Microscope Image Analysis of Bonding Surfaces following Removal of Composite Resin Restoration Using Er: YAG Laser: In Vitro Study

Scanning ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Dlsoz Omer Babarasul ◽  
Bestoon Mohammed Faraj ◽  
Fadil Abdullah Kareem
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Pulse Repetition Rate ◽  
High Speed ◽  
Composite Resin ◽  
Yag Laser ◽  
Group A ◽  
Composite Resin Restoration ◽  
Group B ◽  
Scanning Electron

It is impossible to remove tooth-colored restorations by mechanical means without unnecessary damage to the adjacent sound tooth structure. This study is aimed at investigating erbium-doped yttrium aluminum garnet (Er: YAG) laser (Hoya ConBio, VersaWave, CA, USA) in removing composite resin restorations and assessing the change in morphology of bonding surfaces using a scanning electron microscope (EDX, CAMSCANNER, 3200LV, UK). The investigators collected thirty extracted sound human premolar teeth for this investigation, and the conventional design class V cavity was prepared on the buccal surface of each specimen. The specimens were allocated randomly into three groups, according to the procedure used for the ablation of the composite restoration: group A (high-speed diamond fissure bur), group B, and group C (Er: YAG laser) using a different pulse repetition rate of 20 Hz (group B) and 25 Hz (group C). The AutoCAD software program (Autodesk, Inc., 2016) was used to calculate the surface area and the resulting dimensional change of the cavities after restoration removal. The cavities were filled with composite resin and randomly assigned into two groups conforming to the methods applied to eliminate the restoration; diamond turbine fissure bur and laser. In each group, two specimens were selected randomly for scanning electron microscope analysis of bonding surfaces. The least meantime for the composite resin removal was observed in the high-speed diamond bur, significantly less than both Er-YAG laser groups ( p < 0.001 ). However, at a higher pulse repetition rate, time-consuming decreased. The results showed that laser is more conservative in removing composite resin restoration as the change was most remarkable in group A (0.800 mm), then group C (0.466 mm), and the slightest change is in group B (0.372 mm) ( p = 0.014 ). The dentin surface of group A showed a smooth surface with no opened dentinal tubule and intact smear layer. In groups B and C, dentin surfaces were irregular, scaly, or flaky, and dentinal tubules were opened without a smear layer. Therefore, Er: YAG laser is effective for composite resin removal considering the parameters chosen in this study with fewer changes in cavity surface area and better microretentive features.

scholarly journals COMPOSITE RETENTION CAVITIES;

2019 ◽  
Vol 26 (04) ◽  
Author(s):  
Sara Jamil ◽  
Rizwan Jouhar ◽  
Syed Abrar Ali ◽  
Muhammad Saqib
Keyword(s):  
Randomized Control Trial ◽  
Composite Resin ◽  
Resin Composite ◽  
Class I ◽  
Permanent Molar ◽  
Molar Teeth ◽  
Group A ◽  
Randomized Control ◽  
Composite Resin Restorations ◽  
Group B

Objectives: To compare clinical retention of a low-shrinkage posterior resin composite by using incremental versus bulk placement technique in deep Class I cavities. Setting: Operative Dentistry Department, Altamash Institute of Dental Medicine, Karachi, Pakistan. Period: 6 months from 1st Oct 2017 – 30th March 2018. Study Design: Randomized control trial. Materials and Methods: This study was a randomized control trial study which consists of total of 94 teeth having class I cavity of 3mm minimum depth on occlusal surface. The restorative material evaluated in this study was Filtek Z250 (3M, ESPE) and the cavities were restored according to two different techniques. Patients in Group A were treated with bulk fill technique and patients in Group B were treated with incremental technique. The retention of the composite were clinically evaluated after 6 months (180 days) post-operatively. SPSS version 23 was used to analyze data. Results: The result of 6 months observation revealed retention of 43(91.4%) incremental fill composite and 39(85.4 %) bulk fill composite resin restorations which was statistically insignificant. Conclusion: Outcomes of incremental fill composite resin in terms of retention is equal to bulk fill composite resin with Filtek Z250 (3M, ESPE) in class I restorations of permanent molar teeth.

Gamma Knife surgery as sole treatment for multiple brain metastases: 2-center retrospective review of 1508 cases meeting the inclusion criteria of the JLGK0901 multi-institutional prospective study

2010 ◽  
Vol 113 (Special_Supplement) ◽  
pp. 48-52 ◽  
Author(s):  
Toru Serizawa ◽  
Masaaki Yamamoto ◽  
Yasunori Sato ◽  
Yoshinori Higuchi ◽  
Osamu Nagano ◽  
...  
Keyword(s):  
Brain Metastases ◽  
Gamma Knife ◽  
Class Ii ◽  
Hazard Ratio ◽  
Gamma Knife Surgery ◽  
Inclusion Criteria ◽  
Primary Tumors ◽  
Poor Prognostic Factor ◽  
Group A ◽  
Group B

Object The authors retrospectively reviewed the results of Gamma Knife surgery (GKS) used as the sole treatment for brain metastases in patients who met the eligibility criteria for the ongoing JLGK0901 multi-institutional prospective trial. They also discuss the anticipated results of the JLGK0901 study. Methods Data from 1508 consecutive cases were analyzed. All of the patients were treated at the Gamma Knife House of Chiba Cardiovascular Center or the Mito Gamma House of Katsuta Hospital between 1998 and 2007 and met the following JLGK0901 inclusion criteria: 1) newly diagnosed brain metastases, 2) 1–10 brain lesions, 3) less than 10 cm3 volume of the largest tumor, 4) no more than 15 cm3 total tumor volume, 5) no findings of CSF dissemination, and 6) no impairment of activities of daily living (Karnofsky Performance Scale score < 70) due to extracranial disease. At the initial treatment, all visible lesions were irradiated with GKS without upfront whole-brain radiation therapy. Thereafter, gadolinium-enhanced MR imaging was performed every 2–3 months, and new distant lesions were appropriately retreated with GKS. Patients were divided into groups according to numbers of tumors: Group A, single lesions (565 cases); Group B, 2–4 tumors (577 cases); and Group C, 5–10 tumors (366 cases). The differences in overall survival (OS) were compared between groups. Results The median age of the patients was 66 years (range 19–96 years). There were 963 men and 545 women. The primary tumors were in the lung in 1114 patients, gastrointestinal tract in 179, breast in 105, urinary tract in 66, and other sites in 44. The overall mean survival time was 0.78 years (0.99 years for Group A, 0.68 years for Group B, and 0.62 years for Group C). The differences between Groups A and B (p < 0.0001) and between Groups B and C (p = 0.0312) were statistically significant. Multivariate analysis revealed significant prognostic factors for OS to be sex (poor prognostic factor: male, p < 0.0001), recursive partitioning analysis class (Class I vs Class II and Class II vs III, both p < 0.0001), primary site (lung vs breast, p = 0.0047), and number of tumors (Group A vs Group B, p < 0.0001). However, no statistically difference was detected between Groups B and C (p = 0.1027, hazard ratio 1.124, 95% CI 0.999–1.265). Conclusions The results of this retrospective analysis revealed an upper CI of 1.265 for the hazard ratio, which was lower than the 1.3 initially set by the JLGK0901 study. The JLGK0901 study is anticipated to show noninferiority of GKS as sole treatment for patients with 5–10 brain metastases compared with those with 2–4 in terms of OS.

scholarly journals Outcome of Albumin Infusion in Heart Failure Patients

2019 ◽  
Vol 15 (2) ◽  
pp. 47-53
Author(s):  
Ashaduzzaman Talukder ◽  
Mohamed Mausool Siraj ◽  
Md Noornabi Khondokar ◽  
SM Ahsan Habib ◽  
Md Abu Salim ◽  
...  
Keyword(s):  
Heart Failure ◽  
Serum Albumin ◽  
Nyha Class ◽  
Class Ii ◽  
Class I ◽  
Class Iii ◽  
Albumin Infusion ◽  
Group A ◽  
Group B ◽  
Class Iv

Background: Heart Failure (HF) is a major public health burden worldwide. Approximately 5 million Americans, 0.4–2% of the general European population and over 23 million people worldwide are living with heart failure. Like few other chronic disease, low serum albumin is common in patients with heart failure (HF). However, very few studies evaluated the outcome of albumin infusion in different stages of HF. Therefore, the objective of this study is to assess the outcome of albumin infusion in heart failure patients. Methods: It was a cross-sectional study. A total of 50 cases of chronic heart failure with reduced ejection fraction and NYHA class III or IV with serum albumin level <2.5g/dl who were admitted in CCUwere selected by purposive sampling, from September 2017 to August 2018. 100ml of 20% albumin was infused and serum albumin was measured after 3 days. Then the patients were divided into two groups, Patients who failed to attain serum albumin of 3g/dl(Group A) or Patients who attained serum albumin of ≥3g/dl (Group B). Analysis and comparison for symptomatic improvement of heart failure by NHYA classification and LVEF was done at 10th day after infusion between group A and B. Result: Among the 50 patients, mean age of patients was 53.64 ± 13.44 years (age range: 26-84 years) with a male-female ratio of 3:2 (60%-male vs 40%- female). Majority patients were previously re-admitted at least two times (40%), 28% were re-admitted once, 16% were re-admitted three times and 4% were re-admitted for four times. Of all, 56% patients presented NYHA class IV and AHA stage D heart failure (56%) and 44% patients presented with NYHA class III and AHA stage C. At day 10 follow up following albumin infusion, overall frequency of following ten days of albumin therapy, in group B, 8 patients (72.7%) among Class III improved to Class I and 3 patients (27.3%) improved to class II. Also, 7 patients (50%), 5 patients (35.7%) and 2 patients (14.3%) among class IV improved to respectively class I, class II and class III. In group A, 3 patients (27.3%) among class III improve to class II and 8 patients (72.7%) remain in class III. Also, 2 patients (14.3%), 5 Patients (35.7%) and 7 patients (50%) among class IV improve to respectively class I, class II and class III. Moreover, statistically significant improvement was noted in ejection fraction of patents irrespective of initial class of heart failure (p<0.001) in group B patients compare to group A (p<0.09). Conclusion: In this study, the improvement of heart failure was more in patients who attained albumin level of ≥3g/dl.Therefore, in can be concluded that albumin infusion improves both subjective and objective improvement of patients with heart failure. University Heart Journal Vol. 15, No. 2, Jul 2019; 47-53

scholarly journals Comparison of microleakage of an alkasite restorative material, a composite resin and a resin-modified glass ionomer

2021 ◽  
Vol 20 ◽  
pp. e213981
Author(s):  
Fariba Motevasselian ◽  
Hamid Kermanshah ◽  
Ebrahim Rasoulkhani ◽  
Mutlu Özcan
Keyword(s):  
Composite Resin ◽  
Composite Resins ◽  
Glass Ionomer ◽  
Etch And Rinse ◽  
Significant Difference ◽  
Resin Modified Glass Ionomer ◽  
Group A ◽  
Nanohybrid Composite ◽  
Group B ◽  
Group D

Aim: To compare the microleakage of Cention N, a subgroup of composite resins with a resin-modified glass ionomer (RMGI) and a composite resin. Methods: Class V cavities were prepared on the buccal and lingual surfaces of 46 extracted human molars. The teeth were randomly assigned to four groups. Group A: Tetric N-Bond etch-and-rinse adhesive and Tetric N-Ceram nanohybrid composite resin, group B: Cention N without adhesive, group C: Cention N with adhesive, and group D: Fuji II LC RMGI. The teeth were thermocycled between 5°-55°C (×10,000). The teeth were coated with two layers of nail vanish except for 1 mm around the restoration margins, and immersed in 2% methylene blue (37°C, 24 h) before buccolingual sectioning to evaluate dye penetration under a stereomicroscope (×20). The data were analyzed by the Kruskal-Wallis and Wilcoxon tests (α=0.05). Results: Type of material and restoration margin had significant effects on the microleakage (p<0.05). Dentin margins showed a higher leakage score in all groups. Cention N and RMGI groups showed significant differences at the enamel margin (p=0.025, p=0.011), and for the latter group the scores were higher. No significant difference was found at the dentin margins between the materials except between Cention N with adhesive and RMGI (p=0.031). Conclusion: Microleakage was evident in all three restorative materials. Cention N groups showed similar microleakage scores to the composite resin and displayed lower microleakage scores compared with RMGI.

scholarly journals Effect of Three Different Mouthrinses on Microleakage of Composite Resin Restorations with Two Adhesive Systems after Bleaching with 10% Carbamide Peroxide

2012 ◽  
Vol 13 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Soodabeh Kimyai ◽  
Siavash Savadi Oskoee ◽  
Amir Ahmad Ajami ◽  
Mahmoud Bahari ◽  
Mehdi Abed Kahnamoui ◽  
...  
Keyword(s):  
Composite Resin ◽  
Resin Composite ◽  
Adhesive System ◽  
Adhesive Systems ◽  
Carbamide Peroxide ◽  
Etch And Rinse ◽  
Composite Resin Restoration ◽  
Bonferroni Test ◽  
Composite Resin Restorations ◽  
Resin Restorations

ABSTRACT Aim The aim was to evaluate the effects of Oral-B (OB), Listerine (LN) and Rembrandt Plus (RM) mouthrinses on microleakage of composite resin restorations bonded with two adhesive systems after bleaching with 10% carbamide peroxide. Materials and methods A total of 60 Cl V cavities were prepared on human premolars. The occlusal and gingival margins were placed 1 mm occlusal to and apical to CEJ respectively. The teeth were randomly divided into two groups based on the adhesive system used: Excite (EX) and Clearfil SE Bond (CSE) groups. After composite resin restoration of cavities, thermocycling and bleaching with 10% carbamide peroxide for 2 hours daily for 14 days, the teeth in each adhesive group were further subdivided into three subgroups and were immersed for 12 hours in the three OB, RM and LN mouthrinses. The teeth were then placed in 2% basic fuschin for 24 hours. After dissecting the teeth, microleakage was evaluated under a stereomicroscope at 16×. Data was analyzed with multifactor ANOVA and Bonferroni test at p < 0.05. Results Microleakage with EX was significantly higher than that with CSE (p = 0.009). Microleakage at gingival margins was significantly higher than that at occlusal margins (p = 0.15). Microleakage with OB was higher than that with LN (p = 0.02). However, there were no significant differences in microleakage between LN and RM (p = 1) and between RM and OB (p = 0.15). In addition, with the EX adhesive system, microleakage with OB was higher than that with LN and RM (p = 0.02). Conclusion In the present study, microleakage of composite resin restorations was influenced by the type of the adhesive system, mouthrinse type and the location of the cavity margin. Clinical significance Use of some mouthrinses, such as OB after bleaching can increase postrestoration microleakage of resin composite restorations bonded with etch-and-rinse adhesive systems. How to cite this article Ajami AA, Bahari M, Oskoee SS, Kimyai S, Kahnamoui MA, Rikhtegaran S, Ghaffarian R. Effect of Three Different Mouthrinses on Microleakage of Composite Resin Restorations with Two Adhesive Systems after Bleaching with 10% Carbamide Peroxide. J Contemp Dent Pract 2012;13(1):16-22.

scholarly journals Supraphysiological estradiol levels on the hCG trigger day are associated with SGA for singletons born from fresh embryo transfer

2020 ◽  
Author(s):  
Junwei Zhang ◽  
Mingze Du ◽  
Yanli Wu ◽  
Yiwen Xiong ◽  
Yunxia Wang ◽  
...  
Keyword(s):  
Embryo Transfer ◽  
Reference Group ◽  
Fresh Embryo Transfer ◽  
Group A ◽  
Group B ◽  
Group D ◽  
Estradiol Levels ◽  
Singleton Pregnancies ◽  
Hcg Trigger ◽  
Fresh Embryos

Abstract The effects of supraphysiological estradiol (E2) on neonatal outcomes and the significance of specific E2 concentrations remain unclear. The purpose of this study was investigate whether supraphysiological E2 levels on the hCG trigger day are associated with small size for gestational age (SGA) in singletons born from fresh embryo transfer (ET) cycles. Patients with singleton pregnancies with delivered after transfer of fresh embryos, during the period of July 2012 to December 2017 at our center were included. We excluded cycles involving a vanishing twin, maternal age >35 years, basal FSH ≥10 mIU/ml, AMH ≤1 ng/ml or incomplete records. We then divided all cycles into 5 groups by E2 level on the day of hCG trigger: group A, <2000 pg/ml (reference group); group B, 2000 pg/ml≤E2<2999 pg/ml; group C, 3000 pg/ml≤E2<3999 pg/ml; group D, 4000 pg/ml≤E2<4999 pg/ml; and group E, ≥5000 pg/ml. The prevalence of SGA among singletons from fresh ET was the primary outcome. The SGA rate significantly increased when the E2 level was ≥4000 pg/ml, as observed by comparing groups D (odds ratio [OR]: 1.79, 95% confidence interval [CI]: 1.16–2.76, P=0.01) and E (OR: 1.68, 95% CI: 1.10–2.56, P=0.02) with the reference group. Multivariate logistic regression indicated that a serum E2 level of at least 4000 pg/ml on the hCG trigger day was associated with increased SGA and with significant differences for groups D (adjusted OR [AOR]: 1.65, 95% CI: 1.05–2.59, P=0.03) and E (AOR: 1.60, 95% CI: 1.03–2.53, P=0.04) relative to the reference group. In conclusion，for fresh ET cycles, supraphysiological E2 ≥4000 pg/ml on the hCG trigger day increases the risk of singleton SGA.

New obstetric systemic inflammatory response syndrome criteria for early identification of high-risk of sepsis in obstetric patients

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Jose Rojas-Suarez ◽  
Angel Paternina-Caicedo ◽  
Jezid Miranda ◽  
María Cuello ◽  
María Piñerez ◽  
...  
Keyword(s):  
Systemic Inflammatory Response Syndrome ◽  
Inflammatory Response ◽  
Reference Group ◽  
Systemic Inflammatory Response ◽  
Control Group ◽  
Maternal Outcomes ◽  
Operating Characteristics ◽  
Group A ◽  
Group B ◽  
Obstetric Population

Abstract Objectives We aimed to establish new cut-off values for SIRS (Systemic Inflammatory Response Syndrome) variables in the obstetric population. Methods A prospective cohort study in pregnant and postpartum women admitted with systemic infections between December 2017 and January 2019. Patients were divided into three cohorts: Group A, patients with infection but without severe maternal outcomes (SMO); Group B, patients with infection and SMO or admission to the intensive care unit (ICU); and Group C, a control group. Outcome measures were ICU admission and SMO. The relationship between SIRS criteria and SMO was expressed as the area under the receiver operating characteristics curve (AUROC), selecting the best cut-off for each SIRS criterion. Results A total of 541 obstetric patients were enrolled, including 341 with infections and 200 enrolled as the reference group (Group C). The patients with infections included 313 (91.7%) in Group A and 28 (8.2%) in Group B. There were significant differences for all SIRS variables in Group B, compared with Groups A and C, but there were no significant differences between Groups A and C. The best cut-off values were the following: temperature 38.2 °C, OR 4.1 (1.8–9.0); heart rate 120 bpm, OR 2.9 (1.2–7.4); respiratory rate 22 bpm, OR 4.1 (1.6–10.1); and leucocyte count 16,100 per mcl, OR 3.5 (1.6–7.6). Conclusions The cut-off values for SIRS variables did not differ between healthy and infected obstetric patients. However, a higher cut-off may help predict the population with a higher risk of severe maternal outcomes.

Sign in / Sign up

Export Citation Format

Share Document