scholarly journals Medicinal plants with mosquitoes repellent activity: a systematic review

2022 ◽  
Vol 11 (1) ◽  
pp. e2611124142
Author(s):  
Anderson Ribeiro dos Santos ◽  
Alexia Mota Santos ◽  
Fernando Henrique Oliveira de Almeida ◽  
Vinícius Freitas Arcieri de Medeiros ◽  
Saulo Santos Matos ◽  
...  

Repellents are important allies in trying to prevent diseases transmitted by mosquito bites. Plants have been a source of various repellents and insecticides because they have a large reservoir of bioactive substances, in addition, their products have already been tested and are gaining space in research as a low-cost and easy-access alternative. A systematic review was carried out in the databases, Science Direct, Scielo, SciFinder, Springer, PubMed / Medline, Scopus and Web of Science, evaluated by three reviewers. Titles, abstracts and articles were analyzed in full in English, Spanish and Portuguese. To identify the articles, the following descriptors from the Medical Subject Headings (MeSH) were used: “insect repellents”, “essential oils”, “plants extract”, “repellent activity”, mosquitoes and plants. The bibliographic search resulted in 2274 records. Of these, 27 abstracts were considered potentially relevant, and at the end of the selection, 17 articles were included in their entirety. It was found that medicinal plants showed repellent activity against various species of mosquitoes, however due to the little standardization of the methodologies used and the products obtained it is necessary to develop standardized methods to guarantee the quality and reproducibility of clinical trials with medicinal plants.

2020 ◽  
Vol 9 (9) ◽  
pp. e122996988
Author(s):  
Ellys Cristina Eleonor Pereira Torres ◽  
Jéssica Costa de Oliveira ◽  
Luanne Eugênia Nunes ◽  
Franciso Ernesto de Souza Neto ◽  
Rosueti Diógenes de Oliveira-Filho

Gestational Diabetes Mellitus is a condition characterized by an increase in blood glucose levels, which can be initiated or diagnosed during pregnancy. This process occurs due to the production of high levels of hormones by the placenta, most of which are harmful to the action of insulin in the cells increasing the blood sugar level and can affect the growth and well-being of the fetus. Among the drugs used, Metformin Hydrochloride is an oral hypoglycemic drug used to treat Diabetes Mellitus. The present study aimed to elaborate a systematic review on the use of metformin hydrochloride in the treatment of gestational diabetes mellitus. The searches were carried out in the SciElo and Google Acadêmico databases. 763 articles were found in the initial research and after the analysis of the pre-analytical phases, only 6 were selected, since they met the inclusion criteria. After extracting the data, a relationship was made between the use of metformin with the various forms of therapy used in the studies and it was shown that metformin is a drug well applied as monotherapy, being used by 40 % of individuals in one of the studies analyzed and it is also well accepted in combination therapy with insulin in patients who have resistance to it, due to metformin being a drug with easy access and easy dosage. It is concluded that metformin is a safe, effective, low-cost and widely accepted drug for pregnant women who use it in the treatment of gestational Diabetes Mellitus.


2021 ◽  
Vol 12 (1) ◽  
pp. 13-23
Author(s):  
Juliana Pinheiro ◽  
Luana Amorim Morais da Silva ◽  
Glória Maria França ◽  
Dennys Ramon De Melo Fernandes Almeida ◽  
Amanda Feitoza da Silva ◽  
...  

Cone beam computed tomography is widely used in dentistry, due to its easy accessibility, low cost and better accuracy compared to medical tomography. The present study aims to conduct a systematic review of the literature on the evaluation of jaw bones using cone beam computed tomography. A bibliographic search was performed in the electronic databases PubMed, Scopus, Embase and Web of Science. At the end of the analysis, 10 articles published between 1998 and 2015 were included. Cone beam computed tomography is a precise and fast method, used to evaluate digital images in high resolution, with sharpness, precision. In addition, the acquisition of these images is essential to measure bone elements, in quantity and quality. It should also be noted that the forecast of bone strength will depend on several factors, such as bone density and microarchitecture. Thus, the professional and reduces the likelihood of making mistakes, which interfere with the prognosis of dental treatment.


Author(s):  
Alessia Grigoletto ◽  
Mario Mauro ◽  
Pasqualino Maietta Latessa ◽  
Vincenzo Iannuzzi ◽  
Davide Gori ◽  
...  

This systematic review aimed to investigate the type of physical activity carried out in green urban spaces by the adult population and to value its impact on the population’s health. Additionally, another purpose was to examine if the presence of outdoor gyms in green urban spaces can promote participation in physical activity among adults. Searches of electronic databases, with no time restrictions and up to June 2020, resulted in 10 studies meeting the inclusion criteria. A quantitative assessment is reported as effect size. Many people practiced walking activity as a workout, which showed improvements in health. Walking is the most popular type of training due to its easy accessibility and it not requiring equipment or special skills. Outdoor fitness equipment has been installed in an increasing number of parks and has become very popular worldwide. Further, outdoor fitness equipment provides free access to fitness training and seems to promote physical activity in healthy adults. However, other studies about outdoor fitness equipment efficiency are needed. People living near to equipped areas are more likely to perform outdoor fitness than those who live further away. The most common training programs performed in green urban spaces included exercises with free and easy access, able to promote physical health and perception.


Toxics ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 140
Author(s):  
Francesca Borghi ◽  
Andrea Spinazzè ◽  
Simone Mandaglio ◽  
Giacomo Fanti ◽  
Davide Campagnolo ◽  
...  

Recently, the need to assess personal exposure in different micro-environments has been highlighted. Further, estimating the inhaled dose of pollutants is considerably one of the most interesting parameters to be explored to complete the fundamental information obtained through exposure assessment, especially if associated with a dose-response approach. To analyze the main results obtained from the studies related to the estimation of the inhaled dose of pollutants in different micro-environments (environments in which an individual spends a part of his day), and to identify the influence of different parameters on it, a systematic review of the literature was performed. The principal outcomes from the considered studies outlined that (i) exposure concentration and residence time are among the most important parameters to be evaluated in the estimation of the inhaled dose, especially in transport environments. Further, (ii) the pulmonary ventilation rate can be of particular interest during active commuting because of its increase, which increases the inhalation of pollutants. From a methodological point of view, the advent of increasingly miniaturized, portable and low-cost technologies could favor these kinds of studies, both for the measurement of atmospheric pollutants and the real-time evaluation of physiological parameters used for estimation of the inhaled dose. The main results of this review also show some knowledge gaps. In particular, numerous studies have been conducted for the evaluation (in terms of personal exposure and estimation of the inhaled dose) of different PM fractions: other airborne pollutants, although harmful to human health, are less represented in studies of this type: for this reason, future studies should be conducted, also considering other air pollutants, not neglecting the assessment of exposure to PM. Moreover, many studies have been conducted indoors, where the population spends most of their daily time. However, it has been highlighted how particular environments, even if characterized by a shorter residence time, can contribute significantly to the dose of inhaled pollutants. These environments are, therefore, of particular importance and should be better evaluated in future studies, as well as occupational environments, where the work results in a high pulmonary ventilation rate. The attention of future studies should also be focused on these categories of subjects and occupational studies.


BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e040965
Author(s):  
Sandra Miriam Kawa ◽  
Signe Benzon Larsen ◽  
John Thomas Helgstrand ◽  
Peter Iversen ◽  
Klaus Brasso ◽  
...  

ObjectiveTo investigate the risk of prostate cancer-specific mortality (PCSM) following initial negative systematic transrectal ultrasound-guided (TRUS) prostate biopsies.DesignSystematic review.Data sourcesPubMed and Embase were searched using a string combination with keywords/Medical Subject Headings terms and free text in the search builder. Date of search was 13 April 2020.Study selectionStudies addressing PCSM following initial negative TRUS biopsies. Randomised controlled trials and population-based studies including men with initial negative TRUS biopsies reported in English from 1990 until present were included.Data extractionData extraction was done using a predefined form by two authors independently and compared with confirm data; risk of bias was assessed using the Newcastle–Ottawa Scale for cohort studies when applicable.ResultsFour eligible studies were identified. Outcomes were reported differently in the studies as both cumulative incidence and Kaplan-Meier estimates have been used. Regardless of the study differences, all studies reported low estimated incidence of PCSM of 1.8%–5.2% in men with negative TRUS biopsies during the following 10–20 years. Main limitation in all studies was limited follow-up.ConclusionOnly a few studies have investigated the risk of PCSM following initial negative biopsies and all studies included patients before the era of MRI of the prostate. However, the studies point to the fact that the risk of PCSM is low following initial negative TRUS biopsies, and that the level of prostate-specific antigen before biopsies holds prognostic information. This may be considered when advising patients about the need for further diagnostic evaluation.PROSPERO registration numberCRD42019134548.


2021 ◽  
pp. 1-14
Author(s):  
Adam McDermott ◽  
Ciaran Haberlin ◽  
Jonathan Moran

BACKGROUND: People living with Parkinson’s disease (PD) are less active than healthy individuals. Ehealth is an emerging concept in healthcare which presents opportunities to promote physical activity (PA) in people with PD. The aim of this systematic review was to explore the effectiveness of ehealth in the promotion of PA in people living with PD. METHODS: Suitable articles were searched for using EMBASE, PsychInfo, Web of Science and OVID Medline databases using a combination of keywords and medical subject headings. Articles were included if they described an ehealth intervention designed to promote PA in people living with PD. Two reviewers screened studies for suitability and extracted data. Risk of bias was assessed using the Cochrane risk of bias 2 tool and the Downs and Black risk of bias checklist. Due to the heterogeneity of studies, a narrative synthesis of study interventions and results was completed rather than a quantitative analysis. RESULTS: 1449 articles were screened. Four studies met the eligibility criteria which included 652 participants. Web and mobile applications were used to design the PA interventions. PA levels were measured using self-reported questionnaires, Fitbits, activity monitors and accelerometers. Three of the studies reported improvements in aspects of PA. However, this was not consistently reported in all study participants. No adverse effects, a high level of enjoyment and a relatively low attrition rate (∼12.5%) were reported. CONCLUSION: Ehealth is a safe and feasible intervention to promote PA in this population. It is unclear whether ehealth is effective at promoting PA in people with PD. Keywords:


2021 ◽  
pp. 1-10
Author(s):  
Leonor Grijó ◽  
Carolina Tojal ◽  
Francisca Rego

Abstract Objective Dignity therapy (DT) is a kind of psychotherapy that identifies the main concerns of end-of-life patients that affect their perception of dignity and helps them to find a new meaning in life. Most prior studies on DT analyze outcomes for palliative care patients. The aim of this systematic review is to explore the outcomes of DT in palliative care patients’ family members. Method In June 2020, a bibliographic search was performed using the terms “Dignity Therapy” and “Palliative Care” in the following databases: Cochrane library, TRIP database, PUBMED, Scopus, and Web of Knowledge. Of the 294 articles found, 8 met the selection criteria and were considered in the present study. No articles were excluded based on their publication date. Results Family members generally believe that DT helps them to better prepare the patient's end-of-life and overcome the bereavement phase. The legacy document was considered a source of comfort, and most would recommend DT to other people in their situation. DT is generally considered as important as any other aspect of the patient's treatment. Significance of results There is evidence of the benefits of DT for palliative patients’ family members. However, there are still few studies that evaluate these outcomes. The existing evidence is poorly generalized, and thus, further studies are needed to deeply explore the benefits of this therapy both for patients and their families.


2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1280.2-1281
Author(s):  
A. M. T. Sweeney ◽  
C. Mccabe ◽  
C. Flurey ◽  
J. Robson ◽  
A. Berry ◽  
...  

Background:Nurse-led care has been shown to be clinically effective and cost effective in rheumatoid arthritis (RA) but the role of the nurse in early RA is not well defined. Evidence for processes of care in RA is limited and it is not known how well rheumatology nurse-led clinics meet care needs of people with early RA.Objectives:The aim of this study was to develop an understanding of rheumatology nurse-led care from the perspective of people with early RA.Methods:A qualitative systematic review was conducted. The review protocol is published in the International prospective register of systematic reviews.In March 2019, the following databases were searched: MEDLINE, EMBASE, CINAHL, PsycINFO and OpenGrey. Due to lack of studies in early RA this review included adults with early and established inflammatory arthritis, qualitative studies with data on patients’ perspectives of nurse-led care, published in peer-reviewed journals in English between 2010 and 2019. Two reviewers screened titles, abstracts and full texts. Data were extracted and managed in tables. Joanna Briggs Institute Critical Appraisal Checklist was used for quality assessment of the included studies. A thematic synthesis was undertaken using the framework of Thomas and Harden.1Results:The search identified 1034 records. After screening and assessing for eligibility, 8 qualitative studies were included in the review (133 patients), 2 studies included people with early RA. Three main themes were identified (Figure 1).Figure 1.Themes of nurse-led care from the perspective of people with RAProviding knowledge and skill. This theme delineated rheumatology nursing as providing professional expertise in the planning and delivery of care. The rheumatology nurse-led service included easy access via telephone helpline, consultations with the clinical nurse specialist for assessment of disease activity and care needs, planning of care, disease information and education, supporting self-management, and referral to rheumatologist and the multi-disciplinary team. People with RA highly valued the nurse expertise and specialist knowledge provided at nurse-led clinics.‘She was very good at informing me, so I have only praise for this ... because I have never had it like this before’. (Person with early RA).Using a person-centred approach.This theme showed nurse-led care using a person-centred approach combined with empathy and good communication skills, which created a good therapeutic environment. People with RA appreciated the person-centeredness, empathy and involvement of the nurse. ‘She is very sensitive. She can see if I am feeling bad and comes straight to me and asks: “How are you today?” ...You are treated and taken seriously’. (Person with early RA).Meeting patients‘ care needs. This theme presented nurse-led care as creating a sense of being empowered and psychologically supported in the management of RA and its impact. Nurse-led care made people with RA feel cared for, secure and confident. It added value to rheumatology care and made care complete.‘The thought of sticking a needle into my own stomach... it felt a bit like I would never manage to do that. However, they have been absolutely wonderful here ... and now I can do it myself’. (Person with early RA).Conclusion:Nurse-led care for people with RA is characterised by provision of rheumatology expertise using a person-centred approach, and patients‘ holistic care needs are being met. This study found a dearth of literature on perceptions of nurse-led care in people with early RA, which highlights the need for further research in this population.References:[1]Thomas J, Harden A. Methods for the thematic synthesis of qualitative research in systematic reviews.BMC Med Res Methodol2008; 8: 45.Disclosure of Interests:Anne-Marie Tetsche Sweeney: None declared, Candy McCabe: None declared, Caroline Flurey: None declared, Joanna Robson: None declared, Alice Berry: None declared, Pamela Richards: None declared, Mwidimi Ndosi Grant/research support from: Bristol Myers Squibb, Consultant of: Janssen, Pfizer


Author(s):  
Lily N. Trinh ◽  
Amar Gupta

AbstractInjectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation. A systematic review of the published literature was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and included PubMed, Embase, and Science Direct databases. Medical Subject Headings (MeSH) terms used were “cheek” OR “midface” OR “malar” and “filler” OR “hyaluronic acid” OR “Juvederm” OR “Restylane” OR “Perlane” OR “Belotero.” The initial search identified 699 articles; 256 duplicates were removed. Additional 12 studies were identified from reference lists. A total of 455 were screened by title and abstract and 387 studies were eliminated based on criteria. Also, 68 articles underwent full-text review, and 18 articles were included in the final review and involved seven different HA formulations. Men and women from many age groups were highly satisfied with their results following HA treatment for midface augmentation up to 24 months. The most common adverse events included bruising, swelling, and tenderness, and typically lasted no more than 2 weeks. Upper cheek filler injections near the zygoma should be placed in the submuscular plane while lower cheek injections should be placed in the subcutaneous tissue. HA is an attractive choice for midface augmentation due to its high patient satisfaction, long-lasting effects, and low side-effect profile. Due to the variability in technique, level of expertise, and subjective measurements across studies, one optimal regimen could not be concluded. However, midface augmentation treatment should be personalized to each patient. Additional clinical trials are required to more conclusively determine the most appropriate approach for this procedure.


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