Drawing the Line

Author(s):  
Fiona Sampson
Keyword(s):  

This chapter considers the logic or the ‘line’ or linearity, which signifies the connectedness, or the ‘and then … and then’ process in music and poetry. It illustrates the continuous pattern of notes in a melody and how the notes come one at a time and have a stronger relationship to each other than to other musical lines going on at the same time. They are chronologically connected. Residually, and often actually, they are also connected by something internal, yet constitutive: they share a ‘breath’. In addition, music demonstrates linearity in a different way, by ‘growing’ in parallel to poetry. Fleshing out the themes of linearity between the two genres are rhythms, grammar, and semantics, among many others.

2020 ◽  
Author(s):  
Anat Feldman ◽  
Michael Shmueli ◽  
Dror Dotan ◽  
Joseph Tzelgov ◽  
Andrea Berger

In recent years, there has been growing interest in the development of mental number line (MNL) representation examined using a number-to-position task. In the present study, we investigated the development of number representation on a 0-10 number line using a computerized version of the number-to-position task on a touchscreen, with restricted response time; 181 children from first through sixth grade were tested. We found that the pattern of estimated number position on the physical number line was best fit by the sigmoidal curve function–which was characterized by underestimation of small numbers and overestimation of large numbers–and that the breakpoint changed with age. Moreover, we found that significant developmental leaps in MNL representation occurred between the first and second grades and again between the second and third grades, which was reflected in the establishment of the right endpoint and the number 5 as anchor points, yielding a more accurate placement of other numbers along the number line.


Sports ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 86
Author(s):  
Christoffer Nyborg ◽  
Helene Støle Melsom ◽  
Martin Bonnevie-Svendsen ◽  
Jørgen Melau ◽  
Ingebjørg Seljeflot ◽  
...  

We assessed endothelial function by flow-mediated dilatation (FMD), levels of the NO-precursor L-arginine, and markers of endothelial inflammation before, at the finish line, and one week after the Norseman Xtreme triathlon. The race is an Ironman distance triathlon with a total elevation of 5200 m. Nine male participants were included. They completed the race in 14.5 (13.4–15.3) h. FMD was significantly reduced to 3.1 (2.1–5.0)% dilatation compared to 8.7 (8.2–9.3)% dilatation before the race (p < 0.05) and was normalized one week after the race. L-arginine showed significantly reduced levels at the finish line (p < 0.05) but was normalized one week after the race. Markers of endothelial inflammation E-Selectin, VCAM-1, and ICAM-1 all showed a pattern with increased values at the finish line compared to before the race (all p < 0.05), with normalization one week after the race. In conclusion, we found acutely reduced FMD with reduced L-arginine levels and increased E-Selectin, VCAM-1, and ICAM-1 immediately after the Norseman Xtreme triathlon. Our findings indicate a transient reduced endothelial function, measured by the FMD-response, after prolonged strenuous exercise that could be explained by reduced NO-precursor L-arginine levels and increased endothelial inflammation.


Author(s):  
Priyanka Verma ◽  
Ravinder Kumar Wanchoo ◽  
Amrit Pal Toor

Sulphonate-grafted-Titania (SO3H-TiO2) quantum dot catalyzed photochemical process offered an energy-efficient, accelerated, and safe approach to synthesize lactic acid esters at ambient temperature conditions. This low-temperature route is conceived in line...


Cancers ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 1948
Author(s):  
You-Bin Lee ◽  
Young-Lyun Oh ◽  
Jung-Hee Shin ◽  
Sun-Wook Kim ◽  
Jae-Hoon Chung ◽  
...  

We compared American Thyroid Association (ATA) guidelines, Korean (K)-Thyroid Imaging, Reporting and Data Systems (TIRADS), EU-TIRADS, and American College of Radiology (ACR) TIRADS in diagnosing malignancy for thyroid nodules with nondiagnostic/unsatisfactory cytology. Among 1143 nondiagnostic/unsatisfactory aspirations from April 2011 to March 2016, malignancy was detected in 39 of 89 excised nodules. The minimum malignancy rate was 7.82% in EU-TIRADS 5 and 1.87–3.00% in EU-TIRADS 3–4. In the other systems, the minimum malignancy rate was 14.29–16.19% in category 5 and ≤3% in the remaining categories. Although the EU-TIRADS category ≥ 5 exhibited the highest positive likelihood ratio (LR) of only 2.214, category ≥ 5 in the other systems yielded the highest positive LR of >5. Receiver operating characteristic (ROC) curves of all systems to predict malignancy were located statistically above the diagonal nondiscrimination line (P for ROC curve: EU-TIRADS, 0.0022; all others, 0.0001). The areas under the ROC curve (AUCs) were not significantly different among the four systems. The ATA guidelines, K-TIRADS, and ACR TIRADS may be useful to guide management for nondiagnostic/unsatisfactory nodules. The EU-TIRADS, although also useful, exhibited inferior performance in predicting malignancy for nondiagnostic/unsatisfactory nodules in Korea, an iodine-sufficient area.


1987 ◽  
Vol 63 (4) ◽  
pp. 1586-1590 ◽  
Author(s):  
J. A. Cooper ◽  
H. van der Zee ◽  
B. R. Line ◽  
A. B. Malik

We investigated the dose-response effect of positive end-expiratory pressure (PEEP) and increased lung volume on the pulmonary clearance rate of aerosolized technetium-99m-labeled diethylenetriaminepentaacetic acid (99mTc-DTPA). Clearance of lung radioactivity was expressed as percent decrease per minute. Base-line clearance was measured while anesthetized sheep (n = 20) were ventilated with 0 cmH2O end-expiratory pressure. Clearance was remeasured during ventilation at 2.5, 5, 10, 15, or 20 cmH2O PEEP. Further studies showed stepwise increases in functional residual capacity (FRC) (P less than 0.05) measured at 0, 2.5, 5, 10, 15, and 20 cmH2O PEEP. At 2.5 cmH2O PEEP, the clearance rate was not different from that at base line (P less than 0.05), although FRC was increased from base line. Clearance rate increased progressively with increasing PEEP at 5, 10, and 15 cmH2O (P less than 0.05). Between 15 and 20 cmH2O PEEP, clearance rate was again unchanged, despite an increase in FRC. The pulmonary clearance of aerosolized 99mTc-DTPA shows a sigmoidal response to increasing FRC and PEEP, having both threshold and maximal effects. This relationship is most consistent with the hypothesis that alveolar epithelial permeability is increased by lung inflation.


The Analyst ◽  
2017 ◽  
Vol 142 (8) ◽  
pp. 1244-1257 ◽  
Author(s):  
A. Mignolet ◽  
V. Mathieu ◽  
E. Goormaghtigh

FTIR-based classification of the effect of polyphenols on a breast cancer cell line.


RSC Advances ◽  
2017 ◽  
Vol 7 (9) ◽  
pp. 5282-5296 ◽  
Author(s):  
Marija S. Jeremić ◽  
Hubert Wadepohl ◽  
Vesna V. Kojić ◽  
Dimitar S. Jakimov ◽  
Ratomir Jelić ◽  
...  

Two new Rh(iii)–ed3a complexes [Rh(ed3a)(OH2)]·H2O and Na[Rh(ed3a)Cl]·H2O have shown good antitumor activity, especially against HeLa cell line.


RSC Advances ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 3162-3167
Author(s):  
Ya-jing Wang ◽  
Nan Ma ◽  
Chun-yue Liu ◽  
Yi-xuan Feng ◽  
Feng-xiang Zhang ◽  
...  

Two new xanthones, oxisterigmatocystins J and K, and two new anthraquinones, versicolorins D and E, were characterized from the fungus Penicillium sp. Compounds 4 and 5 showed significant cytotoxic activities against HL-60 cell line.


2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 169-169
Author(s):  
H Manu ◽  
M Fletcher ◽  
K Fang ◽  
Sudario Roberto Silva Junior ◽  
J Dunkelberger ◽  
...  

Abstract The objective of this study was to estimate the effect of sire line on sow and piglet performance during lactation. Commercial Landrace x Large White females (n = 60) were bred to one of the following sire lines: a purebred Duroc line (Line S1), a synthetic (Line S2), or purebred Duroc (Line S3) from a different genetic source. Matings were balanced by line and parity. Females were fed a common gestation and lactation diet during these respective phases. Sow and piglet data were analyzed as a completely randomized design using the GLM procedure of SAS. Results show that, during lactation, females bred to line S3 lost significantly (P = 0.01) more BW (-16.93 ± 3.56 kg) than females bred to line S2 (-2.00 ± 3.50 kg). However, no evidence of a difference (P = 0.18) in BW loss was detected between females bred to line S3 (-16.93 ± 3.56 kg) vs. Line S1 (-7.90 ± 3.56 kg). Further, sows bred to line S3 weaned significantly (P = 0.03) more piglets (12.0 ± 0.28) than females bred to line S2 (10.9 ± 0.27), but not (P = 0.1) compared to females bred to line S1 (11.7 ± 0.27). No significant effect of line (P &gt; 0.05) or parity (P &gt; 0.05) on total number of piglet’s born, number born alive, number of stillborn piglets, or preweaning mortality was detected. The number of mummified fetus tended to be lower in line S2 (0.17 vs 0.66; P = 0.079) and line S3 (0.12 vs 0.66; P = 0.051) sows compared with line S1 sows, respectively. In conclusion, sire line did not have a significant effect on total number born, number born alive, number stillborn, or preweaning mortality. However, females bred to line S3 lost significantly more BW during lact but weaned significantly more piglets than females bred to line S2.


1990 ◽  
Vol 258 (2) ◽  
pp. H529-H539 ◽  
Author(s):  
W. M. Chilian ◽  
K. C. Dellsperger ◽  
S. M. Layne ◽  
C. L. Eastham ◽  
M. A. Armstrong ◽  
...  

We tested the hypothesis that atherosclerosis potentiates coronary vasoconstriction to serotonin and ergonovine. Coronary microvascular pressures and diameters were measured in the beating left ventricle in normal and atherosclerotic cynomolgus monkeys. Pressures were measured in arteries (190–350 microns diam) that were distal to atherosclerotic lesions. Microvascular pressure and simultaneous measurements of aortic pressure and myocardial blood flow were used to calculate segmental vascular resistance (large artery resistance and microvascular resistance) during serotonin, phenylephrine, and ergonovine dosages. Aortic pressure was maintained constant during all interventions. Administration of phenylephrine (50 micrograms.kg-1.min-1 iv) produced a similar increase in microvascular resistance from base line (P less than 0.05) in atherosclerotic and normal animals, 26 +/- 5 and 14 +/- 9 mmHg.min.g.ml-1, respectively. Serotonin (50 micrograms/min) did not influence coronary resistance in normal animals but produced a significant increase in both large artery (8 +/- 3 mmHg.min.g.ml-1) and microvascular resistance (21 +/- 6 mmHg.min.g.ml-1) in atherosclerotic animals (P less than 0.05). A higher dose of serotonin (200 micrograms/min) produced a modest increase in large artery resistance from base line in normal animals (3 +/- 1 mmHg.min.g.ml-1) and a greater increase in atherosclerotic animals (9 +/- 4 mmHg.min.g.ml-1) (P less than 0.05 vs. normals). Ergonovine (10 micrograms.kg-1.min-1 iv) elevated microvascular resistance in both normal and atherosclerotic animals (P less than 0.05) but increased large artery resistance only in atherosclerotic animals (10 +/- 4 mmHg.min.g.ml-1) (P less than 0.05). In summary, coronary vasoconstrictor responses to serotonin and ergonovine were potentiated by atherosclerosis. Because augmented constrictor responses to serotonin were observed in both the diseased arteries and the microcirculation of atherosclerotic animals, we speculate that the pathophysiological consequences of atherosclerosis extend into the microcirculation.


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