Disseminated atypical mycobacteriosis in HIV-infected patient with predominant lesion of digestive system (clinical case)

2020 ◽  
Vol 1 (30) ◽  
pp. 18-23
Author(s):  
A. B. Krivosheev ◽  
M. S. Selyakova ◽  
L. A. Khvan ◽  
S. A. Yeremeeva ◽  
I. V. Zvezdina

The article is devoted to the description of a rarely diagnosed secondary opportunistic infection in an HIV-infected patient – atypical mycobacteriosis. A feature was the predominant lesion of the digestive system. Clinical, laboratory and instrumental research methods and prognosis are analyzed. The diagnosis was verified only by sectional and histological examinations.

Reflection ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 12-17
Author(s):  
E.V. Arkhipov ◽  
◽  
S.I. Zhukova ◽  
N.V. Zaitseva ◽  
◽  
...  

Purpose. To present a rare clinical case of helminthic chorioretinitis in a child and to demonstrate the informative value of a comprehensive analysis of optical coherence tomography (OCT) in identifying the etiological nature of the disease. Methods. The results of clinical, laboratory and instrumental examination of a patient with chorioretinitis caused by ascaris. Results. After etiotropic therapy, the patient had an increase of visual acuity from 0.8 to 1.0 and a two-fold decrease of paracentral scotoma. Conclusion. The presented case shows high informative value of combination of standard analysis of retinal maps and sagittal scans with the complex reconstruction of three-dimensional image and analysis of frontal scans obtained in OCT-angiography (OCTA) mode. Key words: chorioretinitis; helminthiasis; OCT-angiography.


2019 ◽  
pp. 66-76
Author(s):  
I. V. Platitsyn ◽  
A. V. Kondratyev ◽  
A. V. Panin ◽  
E. M. Shubarkina ◽  
A. L. Maslov

Uncomplicated diverticula of the small intestine are asymptomatic, extremely rare in everyday practice and, most often, are detected already with the development of complications such as perforation and abscess formation. Diagnosis of complicated diverticula of the small intestine is difficult due to many other, more common causes of acute abdomen, insufficient use of the capabilities of the methods of radiation diagnosis, the lack of application and correct interpretation of the results of instrumental and special research methods. The article presents a clinical case of perforation of the jejunum diverticulum. The results of effective MDCT diagnosis and successful surgical intervention are presented: laparoscopic resection of the jejunum with the formation of the primary hardware intracorporeal enteroentero-anastomosis side by side. 


2021 ◽  
Vol 5 (1) ◽  
pp. 89-92
Author(s):  
Z. P. Lemeshevskaya ◽  
◽  
M. V. Pavlukevich ◽  
N. I. Procopchik ◽  
◽  
...  

Background. COVID-19 infection keeps changing our understanding of its clinical course when associated with various somatic diseases. Objective. To present a clinical case of a patient with non-specific ulcerative colitis (NUC) and COVID-19 infection. Material and methods: medical documentation, general clinical, laboratory and instrumental data as well as histological examination of bioptates stained with hematoxylin and eosin that were obtained during colonoscopy. Results. The article presents a case history of a patient with manifestations of severe total NUC developed in association with the subclinical form of COVID-19 infection, the former being the cause of death in concomitant pathology. Conclusions. This clinical case describes a variant of an unfavorable outcome of NUC, one of the reasons for the manifestation of which was the atypical form of COVID-19 infection, which became a trigger for an autoimmune inflammatory process in the intestine. The accumulation of new knowledge about the features of the pathogenesis and manifestations of both pathologies will make it possible to improve the effectiveness of treatment and predict the course and outcomes of combined pathology.


Author(s):  
T. Yu. Danzanova ◽  
E. A. Gudilina ◽  
A. A. Kalinina ◽  
P. I. Lepedatu ◽  
G. T. Sinyukova

Purpose: Assessment of the capabilities of the ultrasound method in the diagnostics of a rare Hurthle-cell tumor of the thyroid gland on the example of a clinical case of a patient with malignant neoplasms of independent primary multiple localizations in comparison with other research methods.Material and methods: A comprehensive study of materials from the history of the disease, the results of clinical, laboratory, instrumental, morphological research methods and their comparison with diagnostic cases from literature data.Results: Despite the full comprehensive examination of the patient, including ultrasound, MRI, PET/CT, puncture biopsy under ultrasound control, it was not possible to make the correct diagnosis before the operation. The presence of other malignant diseases in the patient’s history, the presence of altered paratracheal nodes in the same zone, and the rare occurrence of Hurthle thyroid tumors played a role.Conclusions: Hurthle-thyroid cell tumors are a rare disease, but it must always be taken into account in the diagnostic search, since even benign Hurthle tumors have a high risk of malignancy and spreading of distant metastases. 


1999 ◽  
Vol 19 (6) ◽  
pp. 682-685
Author(s):  
Maria P. Varela ◽  
Susie Q. Lew ◽  
Amy M. Smith ◽  
Rachel L. Whyte ◽  
Juan P. Bosch

Author(s):  
N. V. Kochergina ◽  
I. V. Boulytcheva ◽  
S. N. Prokhorov ◽  
A. B. Bludov ◽  
A. V. Fеdorova ◽  
...  

Purpose: Demonstrate a clinical case of poorly differentiated chordoma, confirmed using a wide range of research methods.Material and methods: A 63-year-old female patient with poorly differentiated chordoma who underwent immunohistochemical examination, MRI, CT and scintigraphy.Results: An immunohistochemical study confirmed the morphological affiliation of the tumor, supplemented by the data of imaging methods.Conclusion: The poorly differentiated type of chordoma has a specific immunohistochemical picture, however, differential diagnosis based on imaging methods is currently a difficult task.


2019 ◽  
Vol 100 (4) ◽  
pp. 706-709
Author(s):  
A G Naumov ◽  
K A Boronin ◽  
K V Bokova ◽  
N S Zherebyat'eva ◽  
E V Zhukova ◽  
...  

Timely detection of tuberculosis among the population, both pulmonary and, especially, extrapulmonary, is a priority task of domestic and foreign health care. Often, extrapulmonary forms of tuberculosis mask various other pathologies. For example, laryngeal tuberculosis may be masked as a malignant neoplasm or occur as a nonspecific lesion. The purpose of the article is to attract the attention of medical specialists to the problem of diagnosing tuberculosis on the example of a clinical case of a patient with combined pulmonary and laryngeal tuberculosis. In accordance with the obtained clinical, laboratory and instrumental data, we concluded that when patients are admitted to a non-specialized medical organization with complaints from the larynx (dysphonia, aphonia) or oropharyngeal organs (dysphagia), complete diagnostic minimum is required including chest X-ray, complete blood count, otolaryngology consultation and microbiological monitoring (sputum microscopy) for the purpose of integrated examination of the patient and further routing to antituberculous institution. An example is given of successful treatment of a patient with a combination of pulmonary and extrapulmonary tuberculosis (laryngeal tuberculosis) identified due to the presence of symptoms in the larynx.


2021 ◽  
Vol 20 (3) ◽  
pp. 225-232
Author(s):  
A. V. Teteneva ◽  
V. V. Kalyuzhin ◽  
G. M. Chernyavskaya ◽  
I. D. Bespalova ◽  
G. E. Chernogoryuk ◽  
...  

Idiopathic pulmonary fibrosis (IPF) is one of the most common diseases in the group of interstitial lung diseases, which is characterized by persistent progression and poor prognosis. Over the past decade, experts have made significant progress in developing a diagnostic algorithm for IPF patients. This algorithm includes analysis of clinical, laboratory, and instrumental data, primarily the results of high-resolution computed tomography (HRCT). Precise adherence to the diagnostic algorithm and correct interpretation of HRCT data are prerequisites for IPF diagnosis.Specialists of the Tomsk region have developed routing of patients with suspected IPF. The presented clinical case is a successful example of adhering to this algorithm. Wide implementation of modern diagnostic algorithms into diagnosis and treatment of IPF and quality improvement of imaging methods, primarily HRCT, carried out as a part of the differential diagnosis, open up prospects for early diagnosis of this pathology. A timely prescribed antifibrotic therapy (nintedanib, pirfenidone) in IPF allows to slow down pathological progression and improves the prognosis.


Author(s):  
Cristiane Venturini Garlet ◽  
Isadora de Macedo Tomitão ◽  
Kayque Wellek Delgado do Amaral ◽  
Tiffany Ayumi Negrete Bomura ◽  
Ana Carla Barbosa Lima ◽  
...  

Thyroid storm is a rare condition, but it can be characterized as a threat to life. It presents as an increase in the functions of the thyroid gland due to dysfunction of the central nervous system. It is characterized by pyrexia, tachycardia, heart failure and alterations in the digestive system. The objective of this report is to describe the case of a young woman with no previously reported diseases, who was affected by the thyroid storm, without the presence of Graves' disease.


Vestnik ◽  
2021 ◽  
pp. 345-349
Author(s):  
М.А. Жанузаков ◽  
М.К. Бапаева ◽  
А.Ж. Шурина ◽  
Э.М. Утежанов

Клинические проявления микроскопического полиангиита многообразны, что затрудняет своевременную диагностику и соответственно адекватное лечение. Цель: привлечь внимание терапевтов, пульмонологов, нефрологов к своевременному выявлению легочно-почечного синдрома и установлению его нозологической основы, в частности микроскопического полиангиита на примере клинического случая. Материалы и методы: проведены обследование пациента с микроскопическим полиангиитом и дифференциальная диагностика в рамках легочно-почечного синдрома. Результаты: на основании анамнеза заболевания, результатов клинического и дополнительных методов исследования пациента, установлен диагноз микроскопического полиангиита. Выводы: для ранней диагностики микроскопического полиангиита необходима настороженность при возникновении легочно-почечного синдрома в виде сочетания гломерулонефрита и геморрагического альвеолита на фоне сосудистой пурпуры. Clinical manifestations of microscopic polyangiitis are diverse, which complicates timely diagnosis and, accordingly, adequate treatment. Goal: to draw the attention of therapists, pulmonologists, nephrologists to the timely detection of pulmonary-renal syndrome and the establishment of its nosological basis, in particular microscopic polyangiitis by the example of a clinical case. Materials and methods: an examination of a patient with microscopic polyangiitis and differential diagnosis within the framework of pulmonary-renal syndrome were carried out. Results: based on the anamnesis of the disease, the results of clinical and additional research methods of the patient, the diagnosis of microscopic polyangiitis was established. Conclusions: for early diagnosis of microscopic polyangiitis, alertness is necessary in the event of pulmonary-renal syndrome in the form of a combination of glomerulonephritis and hemorrhagic alveolitis against the background of vascular purpura.


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