Thyroid Storm in a Young Woman: A Clinical Case

2020 ◽  
Vol 5 (10) ◽  
pp. 453-455
Author(s):  
Cristiane Venturini Garlet ◽  
Isadora de Macedo Tomitão ◽  
Kayque Wellek Delgado do Amaral ◽  
Tiffany Ayumi Negrete Bomura ◽  
Ana Carla Barbosa Lima ◽  
...  
Keyword(s):  
Heart Failure ◽  
Central Nervous System ◽  
Young Woman ◽  
Digestive System ◽  
Clinical Case ◽  
Rare Condition ◽  
Thyroid Storm ◽  
Graves Disease ◽  
The Central Nervous System ◽  
Threat To Life

Thyroid storm is a rare condition, but it can be characterized as a threat to life. It presents as an increase in the functions of the thyroid gland due to dysfunction of the central nervous system. It is characterized by pyrexia, tachycardia, heart failure and alterations in the digestive system. The objective of this report is to describe the case of a young woman with no previously reported diseases, who was affected by the thyroid storm, without the presence of Graves' disease.

scholarly journals Myelography and residual contrast in panoramic radiography: case report

2019 ◽  
Vol 67 ◽  
Author(s):  
Barbara Couto RAMOS ◽  
Flávio Ricardo MANZI ◽  
Amaro Ilídio VESPASIANO
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Case ◽  
Panoramic Radiography ◽  
Rare Condition ◽  
Clearance Time ◽  
Radiographic Images ◽  
The Past ◽  
The Central Nervous System ◽  
Contrast Solution

ABSTRACT Myodil or pantopaque is an oil-based contrast solution often used up to 1980 for myelography, cisternography, and ventilography. Oilbased contrasts have a very slow clearance time in the cerebrospinal fluids and may encapsulate for decades and remain in the central nervous system and the interior of the spine. The knowledge of the existence of this rare condition coming from other radiographictests of the past, described in this clinical case, is essential when atypical radiographic images are found.

scholarly journals Acute Disseminated Encephalomyelitis (ADEM): A Demyelinating Disease with Specific Morphological Features

2021 ◽  
pp. 106689692199356
Author(s):  
Fleur Cordier ◽  
Lars Velthof ◽  
David Creytens ◽  
Jo Van Dorpe
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Differential Diagnosis ◽  
Clinical Case ◽  
Demyelinating Disease ◽  
Acute Disseminated Encephalomyelitis ◽  
Demyelinating Diseases ◽  
Demyelinating Disorder ◽  
Immune Mediated ◽  
The Central Nervous System

Acute disseminated encephalomyelitis (ADEM) is a rare immune-mediated inflammatory and demyelinating disorder of the central nervous system. Its characteristic perivenular demyelination and inflammation aid in the differential diagnosis with other inflammatory demyelinating diseases. Here, we present a clinical case of ADEM, summarize its histological hallmarks, and discuss pitfalls concerning the most important neuropathological differential diagnoses.

Central mineralocorticoid receptor blockade decreases plasma TNF-α after coronary artery ligation in rats

2003 ◽  
Vol 284 (2) ◽  
pp. R328-R335 ◽  
Author(s):  
Joseph Francis ◽  
Robert M. Weiss ◽  
Alan Kim Johnson ◽  
Robert B. Felder
Keyword(s):  
Heart Failure ◽  
Central Nervous System ◽  
Nervous System ◽  
Mineralocorticoid Receptor ◽  
Critical Role ◽  
Evaluation Study ◽  
Coronary Artery Ligation ◽  
Artery Ligation ◽  
Tnf Α ◽  
The Central Nervous System

The Randomized Aldactone Evaluation Study (RALES) demonstrated a substantial clinical benefit to blocking the effects of aldosterone (Aldo) in patients with heart failure. We recently demonstrated that the enhanced renal conservation of sodium and water in rats with heart failure can be reduced by blocking the central nervous system effects of Aldo with the mineralocorticoid receptor (MR) antagonist spironolactone (SL). Preliminary data from our laboratory suggested that central MR might contribute to another peripheral mechanism in heart failure, the release of proinflammatory cytokines. In the present study, SL (100 ng/h for 21 days) or ethanol vehicle (Veh) was administered via the 3rd cerebral ventricle to one group of rats after coronary ligation (CL) or sham CL (Sham) to induce congestive heart failure (CHF). In Veh-treated CHF rats, tumor necrosis factor-α (TNF-α) levels increased during day 1 and continued to increase throughout the 3-wk observation period. In CHF rats treated with SL, started 24 h after CL, TNF-α levels rose initially but retuned to control levels by day 5 after CL and remained low throughout the study. These findings suggest that activation of MR in the central nervous system plays a critical role in regulating TNF-α release in heart failure rats. Thus some of the beneficial effect of blocking MR in heart failure could be due at least in part to a reduction in TNF-α production.

scholarly journals Endoscopic Transsphenoidal Approach for Hemangiopericytoma in Sellar Region: A Case Report and Review of the Literature

2021 ◽  
Vol 6 (6) ◽  
Author(s):  
Wang P ◽  
Wang J ◽  
Zou D ◽  
Pan J ◽  
Wu N
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Case Report ◽  
Aggressive Behavior ◽  
Clinical Case ◽  
Transsphenoidal Approach ◽  
Sellar Region ◽  
Review Of The Literature ◽  
The Central Nervous System

Background: Hemangiopericytomas (HPCs) with aggressive behavior are rare in the central nervous system and extremely rare in the sellar region. Here we presented a clinical case of HPC in sellar region.

Central mineralocorticoid receptor blockade improves volume regulation and reduces sympathetic drive in heart failure

2001 ◽  
Vol 281 (5) ◽  
pp. H2241-H2251 ◽  
Author(s):  
Joseph Francis ◽  
Robert M. Weiss ◽  
Shun-Guang Wei ◽  
Alan Kim Johnson ◽  
Terry G. Beltz ◽  
...  
Keyword(s):  
Heart Failure ◽  
Central Nervous System ◽  
Nervous System ◽  
Volume Regulation ◽  
Critical Role ◽  
Coronary Artery Ligation ◽  
Artery Ligation ◽  
Water Excretion ◽  
Beneficial Effects ◽  
The Central Nervous System

The mineralocorticoid (MC) receptor antagonist spironolactone (SL) improves morbidity and mortality in patients with congestive heart failure (CHF). We tested the hypothesis that the central nervous system actions of SL contribute to its beneficial effects. SL (100 ng/h for 28 days) or ethanol vehicle (VEH) was administered intracerebroventricularly or intraperitoneally to rats with CHF induced by coronary artery ligation (CL) and to SHAM-operated controls. The intracerebroventricular SL treatment prevented the increase in sodium appetite and the decreases in sodium and water excretion observed within a week of CL in VEH-treated CHF rats. Intraperitoneal SL also improved volume regulation in the CHF rats, but only after 3 wk of treatment. Four weeks of SL treatment, either intracerebroventricularly or intraperitoneally, ameliorated both the increase in sympathetic drive and the impaired baroreflex function observed in VEH-treated CHF rats. These findings suggest that activation of MC receptors in the central nervous system plays a critical role in the altered volume regulation and augmented sympathetic drive that characterize clinical heart failure.

scholarly journals Thyroid Storm Triggered by Strangulation in a Patient with Undiagnosed Graves’ Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-3 ◽  
Author(s):  
Jorge I. Conte ◽  
Marilyn A. Arosemena ◽  
Kunal Kapoor ◽  
Naomi G. Dempsey ◽  
Megan L. Zaleski ◽  
...  
Keyword(s):  
Risk Factors ◽  
Heart Failure ◽  
Acute Heart Failure ◽  
Altered Mental Status ◽  
Thyroid Storm ◽  
Graves Disease ◽  
First Case ◽  
Local Trauma ◽  
Life Threatening ◽  
High Degree

Thyroid storm is the life-threatening end-organ manifestation of severe thyrotoxicosis. If left untreated, thyroid storm may cause acute heart failure, multiorgan dysfunction, and death. A high degree of suspicion is necessary to make the diagnosis and start antithyroid medications to decrease mortality. Thyroid storm is generally seen in patients with Graves’ disease but should also be suspected in patients with fever, tachycardia, altered mental status, and risk factors including local trauma to the neck, such as strangulation. Based on our review, we report the first case of thyroid storm after strangulation as the presentation of previously undiagnosed Graves’ disease.

scholarly journals Meningioma of the Pineal Region — Differential Radiologic Aspects of Pineal Region Tumors Based on a Clinical Case

2018 ◽  
Vol 37 (02) ◽  
pp. 145-147
Author(s):  
Tiago Avelar ◽  
Aline Paiva ◽  
Márcio Costa ◽  
Guilherme Aguiar ◽  
João Vitorino ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Case ◽  
Pineal Region ◽  
Differential Diagnoses ◽  
Benign Lesions ◽  
Pineal Region Tumor ◽  
Pineal Region Tumors ◽  
The Central Nervous System ◽  
Velum Interpositum

AbstractPineal region tumors are uncommon among neoplasm of the central nervous system, with this region being the most heterogeneous in terms of histological types. Meningiomas are rarer still, but can be found at this site, with origins in either the velum interpositum or falcotentorial junction. Neuroimaging exams can distinguish malignant from benign lesions besides helping to define the origin of the lesion as the pineal parenchymal or surrounding structures. We report the case of a woman with a pineal region tumor in which differential diagnoses included meningioma and germinoma, with confirmation of the former based on radiological characteristics and histopathology. In addition, a brief review of differential diagnoses and approaches for cases of lesions in this region is provided.

scholarly journals Postmortem Quantitative Analysis of Prion Seeding Activity in the Digestive System

Molecules ◽  
2019 ◽  
Vol 24 (24) ◽  
pp. 4601 ◽  
Author(s):  
Katsuya Satoh ◽  
Takayuki Fuse ◽  
Toshiaki Nonaka ◽  
Trong Dong ◽  
Masaki Takao ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Quantitative Analysis ◽  
Prion Protein ◽  
Neurodegenerative Disorders ◽  
Digestive System ◽  
Prion Diseases ◽  
Jakob Disease ◽  
The Central Nervous System ◽  
Almost All

Human prion diseases are neurodegenerative disorders caused by prion protein. Although infectivity was historically detected only in the central nervous system and lymphoreticular tissues of patients with sporadic Creutzfeldt-Jakob disease, recent reports suggest that the seeding activity of Creutzfeldt-Jakob disease prions accumulates in various non-neuronal organs including the liver, kidney, and skin. Therefore, we reanalyzed autopsy samples collected from patients with sporadic and genetic human prion diseases and found that seeding activity exists in almost all digestive organs. Unexpectedly, activity in the esophagus reached a level of prion seeding activity close to that in the central nervous system in some CJD patients, indicating that the safety of endoscopic examinations should be reconsidered.

scholarly journals Refractory neuroblastoma, victory over pain (clinical case)

Pain medicine ◽  
2019 ◽  
Vol 3 (4) ◽  
pp. 64-58
Author(s):  
O O Kalinchuk ◽  
T G Korol ◽  
S S Blazhko ◽  
N U Kosechenko
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Clinical Case ◽  
Adrenal Glands ◽  
Pain Syndrome ◽  
Sympathetic Ganglia ◽  
Protective Mechanism ◽  
Thoracic Cavity ◽  
Oncological Patients ◽  
The Central Nervous System

Neuroblastoma is a malignant tumor that develops from the stem cells of the sympathetic ganglia and the adrenal medulla and belongs to the group of neuroendocrine tumors. It is most often localized in the adrenal glands and the retroperitoneal space, less – in sympathetic ganglia of the neck and thoracic cavity. Pain syn-drome is one of the leading manifestations in patients with disease progression. Unlike other patients, a pain syndrome in oncological patients is not a temporary or periodic sensation, it has no physio-logical expediency, it does not have a protective mechanism, but, on the contrary, pain in this group of patients leads to inadaptation, distorted perception of pain and small impulses, most importantly, accompanied by various disorders of the functions of the central nervous system in the patient’s body.

scholarly journals COMBINATION OF MULTIPLE SCLEROSIS AND HEREDITARY OPTICAL LEBER’S NEUROPATHY. CLINICAL CASE

2021 ◽  
Vol 30 (4) ◽  
pp. 50-54
Author(s):  
Azalia Aisarovna Sokolova ◽  
◽  
Leonid Sergeevich Zemlyanushin ◽  
Elvira Aysarovna Vashkulatova ◽  
Sofia Mikhailovna Zemlyanushina
Keyword(s):  
Multiple Sclerosis ◽  
Central Nervous System ◽  
Nervous System ◽  
Genetic Testing ◽  
Optic Nerve ◽  
Clinical Case ◽  
Demyelinating Disease ◽  
Mcdonald Criteria ◽  
The Central Nervous System ◽  
Hereditary Optic Atrophy

The article discusses a clinical case of demyelinating disease of the central nervous system, multiple sclerosis in combination with Leber’s hereditary optic atrophy of the optic nerve (Harding syndrome). The debut of the disease at the age of 24 in the form of a simultaneous bilateral decrease in vision, with subsequent atrophy of the optic nerves in both eyes. The diagnosis of multiple sclerosis was confi rmed according to the 2017 McDonald criteria, the diagnosis of Leber’s disease was confi rmed by genetic testing. An important point in the diff erential diagnosis was the identifi cation of the G3460A mutation in the ND1 gene and intrathecal synthesis of oligoclonal immunoglobulin G.

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