Efficiency criteria of laboratory support for clinical diagnosis in evaluation of individual life quality and public health elements

2021 ◽  
pp. 55-58
Author(s):  
I. V. Ivanov ◽  
I. I. Skibo ◽  
E. V. Averyanova ◽  
D. S. Bug ◽  
V. L. Emanuel

The analysis of the informativeness of traditional laboratory markers was performed by verification of individuals with the laboratory features of chronic kidney disease (blood creatinine level exceeding the reference range upper limit) among 142,494 people, who underwent laboratory tests during dispenserization and medical examination during 2015–2019. A stable growth of population groups characterized by preclinical hypercreatininaemia was observed, suggesting the increase of chronic kidney disease rate. Meanwhile the frequency of this population group, corresponding to the obtained values, is considered to be a cardiovascular cohort (primarily affected by chronic cardiac failure) in ‘Chronic kidney disease’ clinical recommendation (2019). Our results clearly demonstrate the cardiorenal continuum. Obtained data can be used in the resource support of the health care system calculation.

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Ika Setyo Rini ◽  
Titik Rahmayani ◽  
Efris Kartika Sari ◽  
Retno Lestari

Background: Chronic kidney disease (CKD) is defined as a progressive disease that causes renal failure and requires extended and long-term therapies. CKD patients need to choose one of these therapies to improve their quality of life. This study aims to investigate differences in the quality of life of chronic kidney disease patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis (CAPD).Design and Methods: The study design used is similar to the cross-sectional design. Therefore, in this study observations were carried out, a EQ_5D life quality questionnaire sheet was administered to respondents, and a purposive sampling method was used. The total number of respondents was 250 and consisted of 125 hemodialysis and CAPD patients each.Results: The results obtained using the Mann Whitney method was a p-value (0.515)> α (0.05). These results also included five components, namely the ability to move/walk to an acceptable degree, adequate self-care, performance of usual activities, minimal amount of pain/discomfort during hemodialysis and CAPD, and acceptable levels of anxiety/sadness.Conclusions: This research concludes that there is no difference in the quality of life between CKD patients  undergoing hemodialysis and CAPD.


2018 ◽  
Vol 10 (11) ◽  
pp. 144
Author(s):  
Carmen A. Sierra Llamas ◽  
Rafael E. Donado Castillo ◽  
Gustavo Aroca ◽  
Santos Ángel Depine ◽  
Gladys Gaviria ◽  
...  

The purpose of this study is to determine the levels of anxiety and depression in patients aged between 18 and 70 years, hospitalized with chronic kidney disease in a clinic entity of the city of Barranquilla. The type of research is descriptive, presenting the information through the indicators and statistical tables, the Hospital Scale of Anxiety and Depression of, Zigmond & Smith (1983), which evaluates the detection of depressive and anxious disorders in the non-psychiatric hospital context. The application of the Scale was performed in the hospital entity of the city of Barranquilla to 50 patients with Chronic Kidney Disease. The results they are beneficial in the short term, because they create new research proposals applied to another population group diagnosed with chronic diseases, especially for the evaluation and intervention in the area of health psychology. In the long term, new theories, methods of intervention and evaluation applied to the population of patients with chronic kidney disease will be studied. In the same way, the results show marked trends related to depression, an aspect that is consistent with the deterioration that affects the individual in the course of the disease and also show a positive correlation of the study variables, depression and anxiety disorders in patients with CKD can be due to a symptomatology or consequence of psychological burnout.


2014 ◽  
Vol 27 (4) ◽  
pp. 643-651 ◽  
Author(s):  
Georgia Miranda Tomich ◽  
Luciana Souza Bernardino ◽  
Fabiana Oliveira Ferreira

Introduction Studies have demonstrated beneficial effects of exercise in patients with chronic kidney disease, however, based on current scientific literature, more research is needed to increase evidence level of potential effects of physical activity for this population. Objective To evaluate effects of physical therapy based on the supervised exercise practice on functional capacity and life quality of patients with chronic kidney disease. Material and methods This quasi-experimental study, with repeated measures design, was conducted in the ambulatory of physical therapy, in a public hospital, located in a city of the state of Pará (north region of Brazil). Functional capacity and life quality were assessed at baseline and after six weeks of aerobic and resistance training performed three times per week on alternate days with hemodialysis. Results Eight patients (3M / 5F) with a mean age of 60.38 years (SD = 14.75) were evaluated. There was significant increase of 24% in distance walked in six minute walk test (p = 0.007), and of 47% in number of repetitions during sit-to-stand test (p = 0.002); there was also significant improvement in emotional role (p = 0.043) of life quality assessed with SF36 questionnaire. Conclusion There was a positive impact of only six weeks of rehabilitation with physical exercise on functional capacity and emotional role of life quality of patients with chronic kidney disease.


2020 ◽  
Vol 25 (40) ◽  
pp. 4235-4250 ◽  
Author(s):  
Yu Dong ◽  
Xiaosheng Qu ◽  
Gang Wu ◽  
Xiangdong Luo ◽  
Botao Tang ◽  
...  

Chronic Kidney Disease (CKD) is characterized by the gradual loss of renal mass and functions. It has become a global health problem, with hundreds of millions of people being affected. Both its incidence and prevalence are increasing over time. More than $20,000 are spent on each patient per year. The economic burden on the patients, as well as the society, is heavy and their life quality worsen over time. However, there are still limited effective therapeutic strategies for CKD. Patients mainly rely on dialysis and renal transplantation, which cannot prevent all the complications of CKD. Great efforts are needed in understanding the nature of CKD progression as well as developing effective therapeutic methods, including pharmacological agents. This paper reviews three aspects in the research of CKD that may show great interests to those who devote to bioanalysis, biomedicine and drug development, including important endogenous biomarkers quantification, mechanisms underlying CKD progression and current status of CKD therapy.


2018 ◽  
pp. 32-36
Author(s):  
Elaine Cristina Negri ◽  
Ana Caroline de Lima Sampaio ◽  
Ana Cláudia Pereira da Silva ◽  
Helora Martines Paulo ◽  
Leandro Borsari da Costa ◽  
...  

The chronic kidney disease is multicausal condition with high morbidity and mortality rate, thathas hemodialysis as the main option of treatment. Life quality is a large term which includes physical, psychological and social welfare that is related with happiness perception when compared to external aspects. The research goal wasto rate the welfareof patients with chronic kidney disease that undergoes hemodialysis treatment. The research was made with 63 patients who filled two formularies: one of themabout sample characterizationand instrument WHOQOL-bref made by 26 questions. The data analysis shows that among the analyzed areas, the physical domainhas got the lowest score which may be one of the main factors that influences the welfare.


2020 ◽  
Vol 10 (2) ◽  
pp. 153-157
Author(s):  
Tjung Angela ◽  
Rizaldy Taslim Pinzon

Background: Chronic kidney disease (CKD) is a disease that causes a progressive decrease in kidney function, which can end in kidney failure disease and will have an impact on decreasing quality of life. Previous research has shown that by giving vitamins B1, B6, and B12 can improve quality of life. Aim: To measure changes in quality of life in patients with chronic kidney disease who were given vitamins B1, B6, and B12 parenterally. Material and Methods: This study used quasi experimental (one group pre and post test) in 117 patients who were selected in Bethesda Hospital and Panti Rapih Hospital Yogyakarta hemodialysis unit. Patients were given vitamins B Combination injections twice a week in each hemodialysis for 4 weeks. Quality of life was measured by SF-8 questionnaire on the first day of hemodialysis before given vitamins (pre-test) and on the 30th day, after eight injection of vitamins B1, B6, and B12 (post test). Results: The mean age of observed patients were 51.58 ± 12.51 years. From 117 patients, 73 patients (62,4%) were male and 44 patients (37.6%) were female. The improvement in overall quality of life in patients was not significant (p= 0.055). Quality of life improvement was only significant in the male group (p = 0.016). Conclusion: There was no significant difference after 4-weeks-injections of vitamins B Combination to the overall quality of life in chronic kidney disease patients undergoing hemodialysis. But there was found a significant improvement in quality of life in the male patients with chronic kidney disease who had hemodialysis. Keywords : chronic kidney disease, quality of life, vitamins B1, B6, and B12, SF-8 questionnaire.


e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Cindy R. Senduk ◽  
Stella Palar ◽  
Linda W. A. Rotty

Abstract: The objective of this study is to determine the correlation between anemia and quality of life in chronic kidney disease patients undergoing regular hemodialysis. This was an observational analytical study with a cross-sectional design. Samples were obtained by using consecutive sampling. Patients’ quality of life was assessed with short-form 36 questionnaires (SF-36) while their Hb levels data were taken from the medical records. There were 60 samples, with a majority age range of 50-59 years old (33.33%) adn the dominant gender was males (68,3%). There were 13 non-anemia patients (22%), 27 mild anemia patients (45.0%), 15 moderate anemia patients (25.0%) and 5 severe anemia patients (8%). The highest quality of life score obtained was 90.70 with an average score 61.99. The Spearman correlation test showed a correlation between anemia and life quality (p=0.000). Conclusion: There was a significant correlation between anemia and quality of life in chronic kidney disease patients undergoing regular hemodialysis.Keywords: chronic kidney disease, hemodialysis, anemia, quality of life Abstrak: Tujuan dari penelitian ini untuk mengetahui hubungan anemia dengan kualitas hidup pasien PGK yang sedang menjalani hemodialisis reguler. Desain penelitian yang digunakan adalah analitik observasional dengan rancangan studi potong silang (cross sectional study). Teknik pengambilan sampel yang digunakan yaitu consecutive sampling. Data kualitas hidup pasien diukur dengan pertanyaan dalam kuesioner Short Form (SF-36) sedangkan kadar Hb diambil dari rekam medik. Hasil dari penelitian ini didapatkan sampel 60 orang, usia terbanyak 50-59 tahun (33,3%), jenis kelamin terbanyak adalah laki-laki (68,3%), tidak anemia 13 orang (22%), anemia ringan 27 orang (45,0%), 15 orang (25,0%) anemia sedang dan sisanya 5 orang (8%) anemia berat. Skor kualitas hidup tertinggi 90,70 dengan rata-rata 61,99. Uji korelasi spearman didapatkan hubungan antara anemia dengan kualitas hidup (p=0,000). Simpulan: Terdapat hubungan yang signifikan antara anemia dengan kualitas hidup pasien PGK yang sedang menjalani hemodialisis reguler.Kata kunci: penyakit ginjal kronik, hemodialisis, anemia, kualitas hidup


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