scholarly journals Hubungan anemia dengan kualitas hidup pasien penyakit ginjal kronik yang sedang menjalani hemodialisis reguler

e-CliniC ◽  
2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Cindy R. Senduk ◽  
Stella Palar ◽  
Linda W. A. Rotty
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Short Form ◽  
Life Quality ◽  
Average Score ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
Sf 36

Abstract: The objective of this study is to determine the correlation between anemia and quality of life in chronic kidney disease patients undergoing regular hemodialysis. This was an observational analytical study with a cross-sectional design. Samples were obtained by using consecutive sampling. Patients’ quality of life was assessed with short-form 36 questionnaires (SF-36) while their Hb levels data were taken from the medical records. There were 60 samples, with a majority age range of 50-59 years old (33.33%) adn the dominant gender was males (68,3%). There were 13 non-anemia patients (22%), 27 mild anemia patients (45.0%), 15 moderate anemia patients (25.0%) and 5 severe anemia patients (8%). The highest quality of life score obtained was 90.70 with an average score 61.99. The Spearman correlation test showed a correlation between anemia and life quality (p=0.000). Conclusion: There was a significant correlation between anemia and quality of life in chronic kidney disease patients undergoing regular hemodialysis.Keywords: chronic kidney disease, hemodialysis, anemia, quality of life Abstrak: Tujuan dari penelitian ini untuk mengetahui hubungan anemia dengan kualitas hidup pasien PGK yang sedang menjalani hemodialisis reguler. Desain penelitian yang digunakan adalah analitik observasional dengan rancangan studi potong silang (cross sectional study). Teknik pengambilan sampel yang digunakan yaitu consecutive sampling. Data kualitas hidup pasien diukur dengan pertanyaan dalam kuesioner Short Form (SF-36) sedangkan kadar Hb diambil dari rekam medik. Hasil dari penelitian ini didapatkan sampel 60 orang, usia terbanyak 50-59 tahun (33,3%), jenis kelamin terbanyak adalah laki-laki (68,3%), tidak anemia 13 orang (22%), anemia ringan 27 orang (45,0%), 15 orang (25,0%) anemia sedang dan sisanya 5 orang (8%) anemia berat. Skor kualitas hidup tertinggi 90,70 dengan rata-rata 61,99. Uji korelasi spearman didapatkan hubungan antara anemia dengan kualitas hidup (p=0,000). Simpulan: Terdapat hubungan yang signifikan antara anemia dengan kualitas hidup pasien PGK yang sedang menjalani hemodialisis reguler.Kata kunci: penyakit ginjal kronik, hemodialisis, anemia, kualitas hidup

scholarly journals Differences in the quality of life of chronic kidney disease patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis

2021 ◽  
Vol 10 (2) ◽  
Author(s):  
Ika Setyo Rini ◽  
Titik Rahmayani ◽  
Efris Kartika Sari ◽  
Retno Lestari
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Peritoneal Dialysis ◽  
Kidney Disease ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Life Quality ◽  
P Value ◽  
Minimal Amount ◽  
Cross Sectional

Background: Chronic kidney disease (CKD) is defined as a progressive disease that causes renal failure and requires extended and long-term therapies. CKD patients need to choose one of these therapies to improve their quality of life. This study aims to investigate differences in the quality of life of chronic kidney disease patients undergoing hemodialysis and continuous ambulatory peritoneal dialysis (CAPD).Design and Methods: The study design used is similar to the cross-sectional design. Therefore, in this study observations were carried out, a EQ_5D life quality questionnaire sheet was administered to respondents, and a purposive sampling method was used. The total number of respondents was 250 and consisted of 125 hemodialysis and CAPD patients each.Results: The results obtained using the Mann Whitney method was a p-value (0.515)> α (0.05). These results also included five components, namely the ability to move/walk to an acceptable degree, adequate self-care, performance of usual activities, minimal amount of pain/discomfort during hemodialysis and CAPD, and acceptable levels of anxiety/sadness.Conclusions: This research concludes that there is no difference in the quality of life between CKD patients  undergoing hemodialysis and CAPD.

scholarly journals Hubungan Fatigue Terhadap Kualitas Hidup Pasien Hemodialisa

2021 ◽  
Vol 7 (3) ◽  
pp. 33-39
Author(s):  
Gina Nurdina ◽  
Dian Anggraini
Keyword(s):  
Quality Of Life ◽  
Kidney Disease ◽  
Short Form ◽  
Fatigue Severity Scale ◽  
P Value ◽  
Severity Scale ◽  
Cross Sectional ◽  
Consecutive Sampling ◽  
Fatigue Severity

Latar Belakang : Hemodialisa membantu meningkatkan harapan hidup pasien penyakit ginjal kronis, namun pasien juga sering melaporkan masalah dari pengobatan tersebut salah satunya fatigue yang merupakan gejala paling umum dari pasien hemodialisa dan sering dikaitkan dengan masalah kualitas hidup . Tujuan : Mengetahui hubungan fatigue terhadap kualitas hidup pasien hemodialisis. Metode : Desain penelitian yang digunakan adalah studi korelasional dengan pendekatan cross-sectional. Populasi penelitian ini adalah pasien yang menjalani hemodialisis di berbagai Klinik Hemodialisis di Kota Bandung dengan tehnik pengambilan sampel menggunakan consecutive sampling . Instrumen yang digunakan dalam penelitian ini yaitu the Fatigue Severity Scale (FSS) dan  Kidney Disease Quality of Life Short Form 36 (KDQoL-SF36). Analisis univariat menggunakan distribusi frekuensi. Analisis bivariat dilakukan dengan menggunakan uji korelasi pearson. Hasil : Dari 34 responden sebagian besar pasien mengalami fatigue dengan rerata tingkat fatigue 41.18 (SD=17.11). Sekitar 41% responden memiliki skor fatigue tinggi (45<FAS<=63). Rerata skor KDQoL-SF36 pada aspek daftar gejala/masalah 66.02 (SD=9.06), aspek efek penyakit ginjal 43.70 (SD=10.68), aspek beban penyakit ginjal 12.13 (SD=5.94), aspek komponen kesehatan fisik 35.7 9 (SD=6.58) dan aspek komponen kesehatan mental 45.51 (SD=7.82).  Terdapat hubungan antara fatigue dengan aspek beban penyakit ginjal dan  komponen kesehatan fisik terlihat dari nilai p value <0.05 dengan nilai koefisien korelasi sebesar (-0.491) dan (-0.515). Kesimpulan: Semakin tinggi skor fatigue maka semakin rendah skor aspek kualitas hidupnya

scholarly journals Assessment of Quality of Life in Patients with Chronic Kidney Disease on Maintenance Haemodialysis with Regard to Anaemia - A Descriptive Cross-Sectional Study at a Tertiary Hospital in Kuppam

2021 ◽  
Vol 8 (21) ◽  
pp. 1636-1641
Author(s):  
Uma M.A ◽  
Nagakiran K.V ◽  
Ashwin K ◽  
Lakshmi Visruja R
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
Life Domains ◽  
Sectional Study ◽  
Cross Sectional ◽  
Maintenance Haemodialysis ◽  
Sf 36

BACKGROUND Anaemia is common among chronic kidney disease (CKD) patients. Quality of life (QOL) is a broad multidimensional concept and many factors affect QOL in CKD patients. This study attempted to measure QOL with varying levels of haemoglobin in CKD patients. METHODS The present study was a descriptive cross-sectional study done on CKD patients on maintenance haemodialysis (MHD) after ethical committee approval. All patients aged more than 18 years on MHD for at least 3 months were enrolled in the study. Patients were categorised into 4 separate groups as Hb 4 to < 6 g/dl, 6 to < 8 g/dl, 8 to < 10 g/dl and 10 - 12 g/dl. After obtaining informed consent, participants were given the study questionnaire - kidney disease quality of life (KDQOL) short form (SF - 36) TM V1 .2. RESULTS At different Hb levels, there were significant differences in the kidney symptom/ problem scores (P = 0.000),the burden of kidney disease scores (P = 0.000), the work satisfaction scores (P = 0.014) and the cognitive function scores (P = 0.000). About SF - 36, all of the physical domains were significantly different: physical function scores (P = 0.000), role physical scores (P = 0.045), pain scores (P = 0.000) and general health component scores (P = 0.004) at different Hb levels. For mental domain components, the differences between four groups of Hb levels were significant in the variety of quality of life domains: emotional wellbeing score (P = 0.006), role emotion scores (0.000), social function scores (P = 0.000) and energy/fatigue scores (0.026). CONCLUSIONS KDQOL, SF - 36 showed that the QOL scores are strongly related to Hb concentrations. The higher scores in various quality of life domains were mostly associated with higher Hb levels in the KDQOL - SF scores. Efforts to optimize haemoglobin in CKD patients may show QOL improvement. KEYWORDS Chronic Kidney Disease, Haemodialysis, Anaemia, Quality of Life

Quality of life of patients with Sjogren’s disease with ongoing therapy with diseasemodifying antirheumatic drugs

2020 ◽  
pp. 33-38
Author(s):  
E. Yu. Gan ◽  
L. P. Evstigneeva
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Life Quality ◽  
Well Being ◽  
Disease Modifying Antirheumatic Drugs ◽  
Antirheumatic Drugs ◽  
Sf 36 ◽  
Disease Modifying ◽  
Sjögren’S Disease

Purpose of the study. Assessing the association between the life quality of patients with Sjogren’s Disease and ongoing therapy with various disease-modifying antirheumatic drugs.Material and methods. The study was conducted on the basis of the regional rheumatology center of the consultative diagnostic clinic of the Sverdlovsk Regional Clinical Hospital No. 1. This work is based on the results of a simultaneous study of 74 patients with primary Sjogren’s Disease (SD), distributed in three comparison groups receiving various disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine. The diagnosis of SD was carried out according to European-American criteria AECGC (2002) [18]. In order to analyze the quality of life of patients with SD, the 36-Item Short Form Health Survey (SF‑36) was used. Statistical data processing was carried out using Statistica 7.0 program.Results. Assessment of the quality of life of patients with SD, which is an integrative criterion of human health and well-being, revealed the absence of statistically significant differences (p > 0.05) on eight scales and two health components of the SF‑36 questionnaire in the analyzed groups that differ in the treatment of disease-modifying antirheumatic drugs chlorambucil, methotrexate and hydroxychloroquine.Conclusions. The obtained data indicate an equivalent quality of life in SD patients treated with different disease-modifying antirheumatic drugs methotrexate, chlorambucil and hydroxychloroquine, and therefore hydroxychloroquine can be considered as an alternative basic therapy in patients with SD with certain limitations and contraindications methotrexate and chlorambucil.

HUBUNGAN EFIKASI DIRI DENGAN KUALITAS HIDUP PASIEN GAGAL GINJAL KRONIK YANG MENJALANI HEMODIALISIS

2018 ◽  
Vol 5 (2) ◽  
pp. 56-63
Author(s):  
Abdul Wakhid ◽  
Estri Linda Wijayanti ◽  
Liyanovitasari Liyanovitasari
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Self Efficacy ◽  
Healing Process ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Kolmogorov Smirnov

Background: Self efficacy can optimize the quality of life of clients who undergo the healing process due to chronic diseases. Individuals with higher self-efficacy move their personal and social resources proactively to maintain and improve the quality and length of their lives so that they experience a better quality of life. Objectives: the purpose of this study was to find the correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency. Metode: This type of research was descriptive correlation with cross sectional approach. The samples in this study more 76 people with total sampling technique. The data collection tool for self efficacy was measured by General Self-Efficacy scale, for quality of life with WHOQoL-BREF. Statistical test used Kolmogorov-smirnov. Result: The result showed that self efficacy in patients with chronic kidney disease was mostly in moderate category (53,9%), quality of life in patients with chronic kidney disease was mostly in good category (68,4%). There was a correlation between self efficacy and quality of life of patients with chronic kidney disease who undergo hemodialysis at RSUD Semarang Regency, the result obtained p-value of 0.000 <α (0,05). Suggestion: Patients with chronic kidney disease can maintain good quality of life by helping to generate positive self-esteem and high self efficacy.

scholarly journals Anemia among Chinese patients with chronic kidney disease and its association with quality of life - results from the Chinese cohort study of chronic kidney disease (C-STRIDE)

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Yan Shen ◽  
◽  
Jinwei Wang ◽  
Jing Yuan ◽  
Li Yang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Cohort Study ◽  
Kidney Disease ◽  
Systematic Investigation ◽  
Chinese Patients ◽  
Cross Sectional ◽  
Five Dimensions ◽  
Anemia Treatment

Abstract Background Anemia is one of the common complications in patients with chronic kidney disease (CKD). However, there is no systematic investigation on the prevalence of anemia in CKD patients and its relationship with the quality of life in China. Methods The data for this study comes from baseline data from the Chinese Chronic Kidney Disease Cohort Study (C-STRIDE), which recruited predialysis CKD patients in China. The kidney disease quality of life summary (KDQOL-TM) was used to assess health-related quality of life (HRQoL). Use linear regression model to estimate the relationship between hemoglobin level and quality of life. Results A total of 2921 patients were included in this study. The adjusted prevalence of hemoglobin (Hb) less than 100 g/L was 10.3% (95% confidence interval [CI]: 9.9,11.4%), and showed an increased trend through reduced eGFR levels from 4.0% (95%CI:2.3,5.9%) in the 45-60 ml/min/1.73m2 group to 23.4% (95%CI:20.5,26.2%) in the 15–29 ml/min/1.73m2 group. The prevalence of anti-anemia treatment was 34.0% (95%CI: 28.7,39.3%) and it is shown by reducing eGFR levels from 15.8% (95%CI:0,36.7%) in the 45-60 ml/min/1.73m2 group to 38.2% (95%CI: 30.7,45.2%) in the 15–29 ml/min/1.73m2 group. All five dimensions of the KDQOL scores in patients with CKD decreased as hemoglobin declined. After multivariable adjustments,the degrees of decrease became somewhat blunted. For example, compared with hemoglobin of ≥130 g/L, regression coefficients in the hemoglobin of < 100 g/L were − 0.047(95%CI: − 0.049,-0.045) for Symptoms and Problems(S), − 0.047(95%CI: − 0.049,-0.044) for Effects of the Kidney Disease(E), − 0.207(95%CI: − 0.212,-0.203) for Burden of the Kidney Disease(B), − 0.112(95%CI: − 0.115,-0.109) for SF-12 Physical Functioning (PCS), − 0.295(95%CI: − 0.299, -0.292) for SF-12 Mental Functioning (MCS), respectively. Conclusions In our cross-sectional analysis of patients with CKD in China, prevalence of both anemia and anti-anemia treatment increased with decreased eGFR. In addition, anemia was associated with reduced HRQoL.

Quality of life of children and adolescents with chronic kidney disease: a cross-sectional study

2018 ◽  
Vol 104 (2) ◽  
pp. 134-140 ◽  
Author(s):  
Anna Francis ◽  
Madeleine S Didsbury ◽  
Anita van Zwieten ◽  
Kerry Chen ◽  
Laura J James ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Children And Adolescents ◽  
Family Income ◽  
Cross Sectional Study ◽  
Kidney Transplants ◽  
Cross Sectional ◽  
Factors Associated

ObjectiveThe aim was to compare quality of life (QoL) among children and adolescents with different stages of chronic kidney disease (CKD) and determine factors associated with changes in QoL.DesignCross-sectional.SettingThe Kids with CKD study involved five of eight paediatric nephrology units in Australia and New Zealand.PatientsThere were 375 children and adolescents (aged 6–18 years) with CKD, on dialysis or transplanted, recruited between 2013 and 2016.Main outcome measuresOverall and domain-specific QoL were measured using the Health Utilities Index 3 score, with a scale from −0.36 (worse than dead) to 1 (perfect health). QoL scores were compared between CKD stages using the Mann-Whitney U test. Factors associated with changes in QoL were assessed using multivariable linear and ordinal logistic regression.ResultsQoL for those with CKD stages 1–2 (n=106, median 0.88, IQR 0.63–0.96) was higher than those on dialysis (n=43, median 0.67, IQR 0.39–0.91, p<0.001), and similar to those with kidney transplants (n=135, median 0.83, IQR 0.59–0.97, p=0.4) or CKD stages 3–5 (n=91, 0.85, IQR 0.60–0.98). Reductions were most frequent in the domains of cognition (50%), pain (42%) and emotion (40%). The risk factors associated with decrements in overall QoL were being on dialysis (decrement of 0.13, 95% CI 0.02 to 0.25, p=0.02), lower family income (decrement of 0.10, 95% CI 0.03 to 0.15, p=0.002) and short stature (decrement of 0.09, 95% CI 0.01 to 0.16, p=0.02).ConclusionsThe overall QoL and domains such as pain and emotion are substantially worse in children on dialysis compared with earlier stage CKD and those with kidney transplants.

scholarly journals Predictors of quality of life among patients on dialysis in southern Brazil

2008 ◽  
Vol 126 (5) ◽  
pp. 252-256 ◽  
Author(s):  
Maristela Bohlke ◽  
Diego Leite Nunes ◽  
Stela Scaglioni Marini ◽  
Cleison Kitamura ◽  
Marcia Andrade ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Peritoneal Dialysis ◽  
Short Form ◽  
Outcome Measurement ◽  
Cross Sectional Study ◽  
Southern Brazil ◽  
Cross Sectional ◽  
Sf 36 ◽  
Dialysis Facilities

CONTEXT AND OBJECTIVE: Quality of life (QoL) is considered important as an outcome measurement, especially for long-term diseases such as chronic renal failure. The present study searched for predictors of QoL in a sample of patients undergoing dialysis in southern Brazil. DESIGN AND SETTING: This was a cross-sectional study developed in three southern Brazilian dialysis facilities. METHODS: Health-related QoL of patients on hemodialysis or peritoneal dialysis was measured using the generic Short Form-36 (SF-36) health survey questionnaire. The results were correlated with sociodemographic, clinical and laboratory variables. The analysis was adjusted through multiple linear regression. RESULTS: A total of 140 patients were assessed: 94 on hemodialysis and 46 on peritoneal dialysis. The mean age was 54.2 ± 15.4 years, 48% were men and 76% were white. The predictors of higher (better) physical component summary in SF-36 were: younger age (β-0.16; 95% confidence interval, CI: -0.27 to -0.05), shorter time on dialysis (β-0.06; 95% CI: -0.09 to -0.02) and lower Khan comorbidity-age index (β 5.16; 95% CI: 1.7-8.6). The predictors of higher mental component summary were: being employed (β 8.4; 95% CI: 1.7-15.1), being married or having a marriage-like relationship (β 4.56; 95% CI: 0.9-8.2), being on peritoneal dialysis (β 4.9; 95% CI: 0.9-8.8) and not having high blood pressure (β 3.9; 95% CI: 0.3-7.6). CONCLUSIONS: Age, comorbidity and length of time on dialysis were the main predictors of physical QoL, whereas socioeconomic issues especially determined mental QoL.

scholarly journals HUBUNGAN KOMPLIKASI INTRA HEMODIALISIS DENGAN KUALITAS HIDUP PADA PASIEN CHRONIC KIDNEY DISEASE (CKD) STAGE V YANG MENJALANI HEMODIALISIS DI RUANG HEMODIALISA BRSU TABANAN TAHUN 2017

2018 ◽  
Vol 2 (1) ◽  
pp. 9
Author(s):  
Kadek G Pebriantari ◽  
IGA Puja Astuti Dewi
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Significant Relationship ◽  
Chi Square ◽  
Cross Sectional ◽  
Probability Sampling ◽  
Ckd Stage ◽  
Non Parametric

ABSTRAKLatar Belakang. Hemodialisis aman dan bermanfaat untuk pasien, namun bukan berarti tanpa efek samping. Berbagai komplikasi dapat terjadi pada saat pasien menjalani hemodialisis. Komplikasi ini dapat mengakibatkan timbulnya masalah baru yang lebih kompleks, yaitu dapat mempengaruhi kualitas hidup bahkan menimbulkan kematianTujuan. Untuk mengetahui hubungan komplikasi intra hemodialisis dengan kualitas hidup  pada pasien Chronic Kidney Disease (CKD) Stage V yang menjalani hemodialisis.Metode. Jenis penelitian adalah analitik korelasional dengan pendekatan cross-sectional. Sampel pada penelitian ini berjumlah 166 responden diambil dengan teknik non probability sampling yaitu total sampling. Pengumpulan data menggunakan kuesioner dan lembar observasi,dianalisa dengan uji non parametric (Chi Square).Hasil. Rata – rata jumlah komplikasi intra hemodialisis adalah kurang dari dua komplikasi (sedikit komplikasi). Hipertensi intra hemodialisis adalah komplikasi terbanyak yang ditemukan (52,3%). Kejang dan penurunan kesadaran merupakan komplikasi yang tidak pernah dialami oleh responden selama penelitian (0%).Kualitas hidup pasien CKD stage V yang menjalani HD di BRSU Tabanan masuk dalam kategori kualitas baik. Hasil uji statistik diperoleh nilai p < 0.001 bahwa ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan  kualitas hidup pada pasien yang menjalani HD. Dari hasil analisis diperoleh pula nilai OR = 0,005, artinya responden yang memiliki banyak komplikasi mempunyai peluang 0,005 kali memiliki kualitas hidup buruk dibanding responden yang memiliki sedikit komplikasi.Kesimpulan. Ada hubungan yang signifikan antara komplikasi intra hemodialisis dengan  kualitas hidup pada pasien yang menjalani hemodialisis.KataKunci: Komplikasi Intra Hemodialisis, Kualitas Hidup, Hemodialisis ABSTRACTBackground: Hemodialysis is safe and beneficial to the patient. However, there are various complications may occur when the patients undergo hemodialysis. These complications can lead to the emergence of new problems which are more complex and affect to the quality of life and even cause death.Aim: To determine the relationship of intra hemodialysis complications with quality of life in patients with Chronic Stage Kidney Disease (CKD) Stage V who undergo hemodialysis.Method:This study employed correlational analytic design with cross-sectional approach. To conduct this study, there were 166 respondents recruited as the sample by using probability sampling with total sampling technique. The data were collected by using questionnaire and observation sheet. Further, the data were analyzed by non-parametric test (Chi Square).Finding: The findings indicated that the average number of intra hemodialysis complications is less than two complications (few complications). There were found that 52.3% patients who had complication of hypertension intra hemodialysis. On the other hand, there was 0%of the respondents experienced seizures and decreased awareness complications during the study. The quality of life of CKD stage V patients underwenthemodialysis at BRSU Tabanan is categorized as good quality. The statistical test obtained p <0.001, it meant that there was a significant relationship between intra hemodialysis complications with quality of life in patients underwenthemodialysis. It also found that the analysis results of OR = 0.005, it meant that respondents who had many complications have a chance of 0.005 times experienced poor quality of life rather than the patients who had few complications.Conclusion: There is a significant relationship between intra hemodialysis complications and quality of life in patients undergo hemodialysis. Keywords: Complications of Intra Hemodialysis, Quality of Life, Hemodialysis

scholarly journals Better health-related quality of life in kidney transplant patients compared to chronic kidney disease patients with similar renal function

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257981
Author(s):  
Jung-Hwa Ryu ◽  
Tai Yeon Koo ◽  
Han Ro ◽  
Jang-Hee Cho ◽  
Myung-Gyu Kim ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
Over Time

Renal functional deterioration is associated with physical and mental burdens for kidney transplant (KT) and chronic kidney disease (CKD) patients. However, the change in health-related quality of life (HRQOL) over time in KT patients compared to that of native CKD patients has not been evaluated. We addressed this issue using KT patients registered in the KNOW-KT cohort study and patients at CKD stage 1–3 registered in the KNOW-CKD cohort study. HRQOL scores were assessed using the Kidney Disease Quality of Life Short Form at baseline, 2-, and 4-years follow-up in 842 KT patients and at baseline and 5-year follow-up in 1,355 CKD patients. SF-36 scores declined at the 4-year follow-up, whereas CKD-targeted scores showed no change in the KT group. In contrast, CKD-targeted scores as well as SF-36 scores were decreased at the 5-year follow-up in CKD patients. When prognostic factors were analyzed for longitudinal HRQOL data over time, renal functions, diabetes, cardiovascular and cerebrovascular diseases, hemoglobin level, marital status, income, employment, and health care were significant prognostic factors. Furthermore, KT was an independent prognostic factor for better HRQOL. These results highlight that KT can offer a better HRQOL than that of CKD patients, even when renal function is similar.

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