scholarly journals Age Dependent Analysis of Colon Cancer Tumours Using Mathematical and Statistical Modelling

Author(s):  
Vidya Bhargavi Machavaram ◽  
Sireesha Veeramachaneni

Colon cancer is the third most commonly diagnosed cancer and the second leading cause of cancer death in men and women combined in the United States. In this work, we performed mathematical and statistical modelling of Tumour sizes as a function of age for four different races. Mathematically, based on the behaviour of the data for each race, we partitioned ages of subjects into several intervals. The mathematical function that characterizes the size of the Tumour as a function of age was determined for each age interval. Statistically, using quantile regression, we designed models that are more robust at specific quantiles using Tumour size and age as dependent and predictor variables.

2005 ◽  
Vol 3 (4) ◽  
pp. 468 ◽  

Colorectal cancer is the third most frequently diagnosed cancer in men and women in the United States, and in 2005, an estimated 104,950 new cases of colon cancer will occur. Despite these statistics, mortality from colon cancer has decreased over the past 30 years, possibly because of earlier diagnosis through screening and better treatment modalities. The NCCN guidelines summarize the management of colon cancer, from disease presentation through management of recurrent disease and patient surveillance. For the most recent version of the guidelines, please visit NCCN.org


2018 ◽  
Vol 11 (3) ◽  
pp. 791-796 ◽  
Author(s):  
Tagore Sunkara ◽  
Megan E Caughey ◽  
Priyanka Makkar ◽  
Febin John ◽  
Vinaya Gaduputi

Overall, colorectal cancer is the third most commonly diagnosed cancer in both men and women, meaning that it is one of the more widely recognized preventable cancers. Instances of colorectal malignancies though are overwhelmingly attributable to adenocarcinoma. Colorectal cancers with components of squamous cell carcinoma represent a statistical anomaly. Here, we present the case of a 50-year-old male, who complained of abdominal pain and weight loss over a 3-month period of time. Biopsies from a colonoscopy ultimately revealed that this patient’s colon cancer consisted of both adenocarcinoma and squamous cell carcinoma, representing a truly exceptional pathology finding in a patient diagnosed with a colorectal cancer.


2007 ◽  
Vol 5 (9) ◽  
pp. 884 ◽  
Author(s):  
_ _

Colorectal cancer is the third most frequently diagnosed cancer in men and women in the United States. An estimated 112,340 new cases of colon cancer will occur in 2007 and an estimated 52,180 people will die from colon and rectal cancer in the same year. Despite these statistics, mortality from colon cancer has decreased over the past 30 years, possibly because of earlier diagnosis through screening and better treatment modalities. These guidelines begin with the clinical presentation of the patient to the primary care physician or gastroenterologist and address diagnosis, pathologic staging, surgical management, adjuvant treatment, management of recurrent and metastatic disease, and patient surveillance. For the most recent version of the guidelines, please visit NCCN.org


Author(s):  
Utku Dönem Gündoğdu ◽  
Funda Karabağ Çoban

Colon cancer is a tumor of the large intestine. It is the third most common cause of cancer-related death in the United States. However, most people with colon cancer get better if the cancer is found early. The atherogenic index of plasma (AIP), triglyceride-glucose (TyG) index, are strongly associated with atherogenesis of the coronary artery however, studies on its relationship with cancer are limited in the literature. This study aimed to investigate the association of the AIP, TyG index, and Monocyte/HDL-C with colon cancer patients.


Author(s):  
Ramachandran K ◽  
Venketnarayanan R ◽  
Rajesh Yadav ◽  
Suresh R ◽  
Sumitra Devkota

Colorectal cancer is the second leading cause of cancer death in the United States for both men and women. The rate of colon cancer incidence was low in India but is presently increasing; out of 3.5 million cancer cases, 35,000 have colon cancer. Polyps which are the small growths in the colon are most often benign, even though some have the potentiality to become cancerous. Up to two-thirds of the colorectal polyps are pre-malignant and they are linked with a risk of colorectal cancer. About 60% of currently used anti-cancer agents are derived from a natural source (i.e. plants). In our study anti-cancer potential of the extract of Coldenia procumbens was studied and the synthesis of the anti-cancer moiety has been done. With the findings, it can be concluded that the plant Coldenia procumbens Linn and possess anti colorectal cancer activity. Before the clinical usage of extract, through toxicological profile has to be determined on the crude extracts as well as on isolated compounds to confirm the safety of the drug.


Author(s):  
Tiffany Hale

To identify Clyde Warrior as an intellectual subverts prevailing notions of intellectualism. We often think of intellectuals as older men and women whose major contributions are revealed late in life, once the passions of youth have been tempered by experience. Warrior was not this. People frequently imagine intellectuals as existing in isolation, insulated from the demands of regular folk. Warrior was not this either. He was a Ponca, born on the reservation and raised with the influence of his grandparents and community. He was also a renowned singer and powwow fancy dancer, as well as a college student, an organizational leader, a husband, and father of two daughters. Warrior’s political consciousness grew out of the deep connections he maintained to his rural Ponca roots, but he took care to educate himself about the problems affecting Native Americans across the United States as well as colonized peoples globally. As an Oklahoman, he was attuned to race relations in the South and empathized with the struggles of Africans and African Americans. His approach to indigenous political struggles was shaped and informed, for example, by his early and active participation with the Student Nonviolent Coordinating Committee (SNCC) and Martin Luther King Jr.’s Poor People’s Campaign.


Submit Manuscript | http://medc rav eonline.co m Introduction Colorectal adenocarcinoma is the third most common malignant neoplasia and the third leading cause of death from cancer in men and women in the United States. Current data show that the incidence of colorectal adenocarcinoma is decreasing in developed countries but increasing in developing countries. 1 The 2018 estimates of the Bra - zilian National Cancer Institute (Instituto Nacional do Câncer–INCA) were 17,380 new cases in men and 18,980 in women, making col - orectal adenocarcinoma the third most common neoplasia in men and the second most common in women in Brazil. 2 In the past 15 years, rectal cancer management has evolved in several aspects. Specifical - ly, a better understanding of the natural history of the disease, more precise radiological staging, multimodal therapeutic intervention, refined surgical techniques, and more detailed histopathological re - ports may have positively influenced patient survival. In this context, multidisciplinary management of colorectal cancer plays an important role and requires the coordinated teamwork of colorectal surgeons, oncologists, radiologists, and radiotherapists. 3 Total mesorectal exci - sion is still the basis of treatment in rectal cancer. However, neoadju - vant therapy and more conservative practices have been adopted in cases of clinical/pathological responses to radiochemotherapy. 4 Ra - diological evaluation of the response is of paramount importance for the selection of patients eligible for alternative treatment strategies, including ‘watch-and-wait’. Diffusion-weighted imaging is already being used routinely in the evaluation of the pathological response of rectal tumour patients submitted to neoadjuvant therapy. Some re - searchers have tried to estimate the tumour regression grade (TRG) using magnetic resonance imaging, as has been described for post-ra - diochemotherapy pathological evaluation, thus rendering it a valuable instrument. Considering the good results obtained with multimodal therapy in extraperitoneal rectal cancer, the evaluation of the pathological re - sponse post-neoadjuvant therapy must be considered as a factor for safe indication, both for the conservative option, in which the organ is preserved, and for radical surgical resection, influencing the choice between sphincter-preserving surgery and abdominoperineal excision. A precise evaluation, by comparing the results of post-neoadjuvant therapy magnetic resonance imaging with those obtained from his - Int J Radiol Radiat Ther. 2018;5(4):254 ‒ 258. 254 © 2018 Oliveira et al. This is an open access article distributed under the terms of the Creative Commons Attribution License , which permits unrestricted use, distribution, and build upon your work non-commercially. Magnetic resonance imaging is effective in assessing tumour regression after neoadjuvancy in rectal adenocarcinoma

Author(s):  
Fábio Henrique de Oliveira ◽  
Antônio Lacerda-Filho ◽  
Fábio Lopes de Queiroz ◽  
Tatiana Martins Gomide Leite ◽  
Paulo Guilherme Oliveira Sales ◽  
...  

2015 ◽  
Vol 4 (1) ◽  
Author(s):  
Siluvai Raja

Education has been considered as an indispensable asset of every individual, community and nation today. Indias higher education system is the third largest in the world, after China and the United States (World Bank). Tamil Nadu occupies the first place in terms of possession of higher educational institutions in the private sector in the country with over 46 percent(27) universities, 94 percent(464) professional colleges and 65 percent(383) arts and science colleges(2011). Studies to understand the profile of the entrepreneurs providing higher education either in India or Tamil Nadu were hardly available. This paper attempts to map the demographic profile of the entrepreneurs providing higher education in Arts and Science colleges in Tamil Nadu through an empirical analysis, carried out among 25 entrepreneurs spread across the state. This paper presents a summary of major inferences of the analysis.


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