scholarly journals Population Genetic Analysis and Sub-Structuring of Theileria annulata in Sudan

2021 ◽  
Vol 12 ◽  
Author(s):  
Diaeldin A. Salih ◽  
Awadia M. Ali ◽  
Moses Njahira ◽  
Khalid M. Taha ◽  
Mohammed S. Mohammed ◽  
...  
Keyword(s):  
Vaccine Strain ◽  
Animal Movement ◽  
Theileria Annulata ◽  
Linkage Equilibrium ◽  
Population Genetic Analysis ◽  
Tropical Theileriosis ◽  
The North ◽  
Field Samples ◽  
East And West ◽  
High Level

Theileria annulata, which causes tropical theileriosis, is a major impediment to improving cattle production in Sudan. Tropical theileriosis disease is prevalent in the north and central regions of Sudan. Outbreaks of the disease have been observed outside the known endemic areas, in east and west regions of the country, due to changes in tick vector distribution and animal movement. A live schizont attenuated vaccination based on tissue culture technology has been developed to control the disease. The parasite in the field as well as the vaccine strain need to be genotyped before the vaccinations are practiced, in order to be able to monitor any breakthrough or breakdown, if any, after the deployment of the vaccine in the field. Nine microsatellite markers were used to genotype 246 field samples positive for T. annulata DNA and the vaccine strain. North and central populations have a higher multiplicity of infection than east and west populations. The examination of principal components showed two sub-structures with a mix of all four populations in both clusters and the vaccine strain used being aligned with left-lower cluster. Only the north population was in linkage equilibrium, while the other populations were in linkage disequilibrium, and linkage equilibrium was found when all samples were regarded as single population. The genetic identity of the vaccine and field samples was 0.62 with the north population and 0.39 with west population. Overall, genetic investigations of four T. annulata populations in Sudan revealed substantial intermixing, with only two groups exhibiting regional origin independence. In the four geographically distant regions analyzed, there was a high level of genetic variation within each population. The findings show that the live schizont attenuated vaccine, Atbara strain may be acceptable for use in all Sudanese regions where tropical theileriosis occurs.

scholarly journals Contrasting population genetics of cattle- and buffalo-derived Theileria annulata causing tropical theileriosis

2020 ◽  
Author(s):  
Umer Chaudhry ◽  
Qasim Ali ◽  
Lynn Zheng ◽  
Imran Rashid ◽  
Muhammad Zubair Shabbir ◽  
...  
Keyword(s):  
Cytochrome B ◽  
Water Buffalo ◽  
Theileria Annulata ◽  
Tropical Theileriosis ◽  
Multiple Introductions ◽  
Individual Host ◽  
Mitochondrial Cytochrome B ◽  
Different Strains ◽  
The Individual ◽  
High Level

AbstractThe present study was designed to improve understanding of Theileria annulata in sympatric water buffalo and cattle in the Punjab province of Pakistan. The prevalence of tropical theileriosis is high, buparvaquone resistance is widespread, and vaccine protection is poor in the field. Better understanding is, therefore, needed of the factors that influence the genetics of T. annulata populations both within its hosts and in its overall populations. Here we utilise a panel of six satellites and a mitochondrial cytochrome b marker to explore the multiplicity of T. annulata infection and patterns of emergence and spread of different parasite genotypes. Parasite materials were collected from infected animals in defined regions, where water buffalo and cattle are kept together. Our results show that T. annulata is genetically more diverse in cattle- than in water buffalo-derived populations (the mean numbers of unique satellite alleles were 13.3 and 1.8 and numbers of unique cytochrome b locus alleles were 65 and 27 in cattle- and water buffalo-derived populations, respectively). The data show a high level of genetic diversity among the individual host-derived populations (the overall heterozygosity (He) indices were 0.912 and 0.931 in cattle, and 0.874 and 0.861 in buffalo, based on satellite and cytochrome b loci, respectively). When considered in the context of high parasite transmission rates and frequent animal movements between different regions, the predominance of multiple T. annulata genotypes, with multiple introductions of infection in the hosts from which the parasite populations were derived, may have practical implications for the spread of parasite genetic adaptations; such as those conferring vaccine cross-protection against different strains affecting cattle and buffalo, or resistance to antiprotozoal drugs.

The Scottish Herring Trade, 1470–1600

2005 ◽  
Vol 84 (2) ◽  
pp. 149-165 ◽  
Author(s):  
Martin Rorke
Keyword(s):  
Sixteenth Century ◽  
West Coast ◽  
North West ◽  
Capital Costs ◽  
The North ◽  
East And West

This paper uses customs figures to show that herring exports from the east and west coast lowlands expanded significantly in the last six decades of the sixteenth century. The paper argues that the rise was primarily due to the north-west Highland fisheries being opened up and exploited by east and west coast burghs. These ventures required greater capital supplies and more complex organisation than their local inshore fisheries and they were often interrupted by political hostilities. However, the costs were a fraction of those required to establish a deepwater buss fleet, enabling Scotland to expand production and take advantage of European demand for fish while minimising additional capital costs.

Her Majesty Queen Rania Al Abdullah

2019 ◽  
Author(s):  
Adib Rifqi Setiawan
Keyword(s):  
Education System ◽  
Ministry Of Education ◽  
Childhood Experiences ◽  
The Sustainable Development ◽  
American University ◽  
The North ◽  
The World ◽  
Development Goals ◽  
High Level ◽  
Education And Development

“The real treasure is in the minds of our children, and all we have to do is extract it.” Her Majesty Queen Rania Al Abdullah writes in website Queen Rania Foundation For Education And Development www.qrf.org/en. Rania Al Yassin was born on August 31, 1970. She obtained her Bachelor’s degree in Business Administration from the American University of Cairo in 1991. She applied this, first, to a banking career in Jordan and, later, to the information technology sector. After marrying Prince Abdullah bin Al Hussein on June 10, 1993, they went on to have four children: Prince Hussein, Princess Iman, Princess Salma, and Prince Hashem. In addition to being a wife and mother, Queen Rania works hard to lift the lives of Jordanians by supporting their endeavours and helping to create new opportunities for them. Locally, she is committed to breathe new life into the public education system; empower communities and women especially through microfinance initiatives; protect children and families; and drive innovation, technology and entrepreneurship, especially amongst young people. Internationally, Queen Rania is an advocate for tolerance, compassion and bridge building between people of all cultures and backgrounds. Her efforts to simultaneously challenge stereotypes of Arabs and Muslims, and promote greater understanding and acceptance between people of all faiths and cultures, have won her global recognition. Her Majesty’s passion is education. She believes that every Jordanian girl and boy, and all children, should have access not only to stimulating classrooms and modern curricula, but inspiring teachers and technology that can connect Jordan’s children to the world and the world to Jordan’s children. Her efforts in the education sector complement the work of the Ministry of Education through initiatives such as the Jordan Education Initiative, the Queen Rania Teachers Academy, Madrasati, Edraak and others. To realize these and so much more, Queen Rania has encouraged private sector partners to drive improvements and strengthen the foundations of Jordan’s education system. Queen Rania is also a global voice for access to quality education for children around the world. In 2009, Her Majesty championed the 1 Goal campaign for education; she is Honorary Chair of the UN Girl’s Education Initiatives and has advocated access to education in forums and gatherings around the world. Her work and her efforts to improve the learning opportunities for children have been recognized at the highest levels, nationally, regionally and internationally. Additionally, through her position on their boards, Her Majesty contributes to the work of the United Nations Fund and the World Economic Forum. She is the Eminent Advocate for UNICEF; and she was part of the UN appointed High Level Panel who advised on the shape and content of the Sustainable Development Goals which aim to improve the lives of millions of people before 2030. In recognition of her work, Her Majesty has humbly accepted many awards, locally, regionally and globally. These include the Walther Rathenau Award from the Walther RathenauInstitut in Germany for her efforts to greater peace and understanding; the James C. Morgan Global Humanitarian Award from Tech Awards, USA; the Arab Knight of Giving Award from Arab Giving Forum, UAE; the North South Prize by the North South Prize, Portugal; as well as the YouTube Visionary Award. Her Majesty authored several books primarily for children including the Sandwich Swap, which was inspired by her own childhood experiences.

Fertility in Cheviot ewes. 2. The effect of level of pre-mating nutrition on ovulation rate and early embryo mortality in North and South Country Cheviot ewes in moderately-good condition at mating

1979 ◽  
Vol 29 (1) ◽  
pp. 17-23 ◽  
Author(s):  
R. G. Gunn ◽  
J. M. Doney ◽  
W. F. Smith
Keyword(s):  
Food Intake ◽  
Good Condition ◽  
Early Embryo ◽  
Ovulation Rate ◽  
Corpora Lutea ◽  
Restricted Feeding ◽  
Embryo Mortality ◽  
The North ◽  
Breed Difference ◽  
High Level

ABSTRACTIn two experiments over 2 years, 57 North Country Cheviot and 82 South Country Cheviot hill ewes were differentially group-fed indoors over a 2-month period to achieve either good or moderate body con- dition. Over 5 weeks prior to mating, ewes in good condition were brought down in condition by restricted feeding and ewes in mod- erate condition were raised in condition by a high level of feeding. The ewes were thus in moderately-good condition at mating. After mating, ewes were maintained in this condition until killed either on return to service or at 29 ± 8 days for counts of corpora lutea and viable embryos.Ovulation rate in each breed was positively related to the level of pre-mating food intake at the condition level studied. Embryo mortality, as ova loss, was not influenced overall by the level of pre-mating food intake but loss of multiple-shed ova was greater than that of single-shed ova in ewes which had been on restricted feeding before mating. Although a greater proportion of ewes in the North Country Cheviot breed were not pregnant at slaughter, this could not be identified as a breed difference since the breeds were studied in different years.

scholarly journals On the height of the Aurora Borealis above the surface of the Earth; particularly one seen on the 29th of March, 1826

1833 ◽  
Vol 2 ◽  
pp. 342-344 ◽  
Keyword(s):  
Scientific Journals ◽  
Apparent Position ◽  
Aurora Borealis ◽  
Far North ◽  
The North ◽  
The Earth ◽  
East And West ◽  
Magnetic Meridian ◽  
North And South

The author observes that opinions differ as to the elevation of the Aurora Borealis above the surface of the earth, and that this is a point which can be determined only by a series of concurring observations. The appearance of a phenomenon of this kind on the 29th of March, 1826, assuming the form of a regular arch at right angles to the magnetic meridian, and marked by peculiar features, continuing for above an hour in the same position, afforded a most favourable opportunity for obtaining the data requisite for the solution of this problem; and the author accordingly took great pains to collect as many authentic accounts as possible of the apparent position of this luminous arch with reference to the stars, when seen from various places where it had been observed in England and in Scotland. It appears to have been actually seen in places 170 miles distant from one another, in a north and south direction, and 45 miles distant from east to west, thus comprising an area of 7000 or 8000 square miles; but it must have been visible over a much greater extent. Accounts were received of its having been seen as far north as Edinburgh, and as far south as Manchester and Doncaster, and at most of the intermediate towns; and from the exact; correspondence of the descriptions from all these places, it was impossible to doubt that they referred to the same luminous appearance. In proceeding from north to south, the apparent altitude of the arch continually increased, still keeping to the south of the zenith till we come to Kendal, at which place it very nearly crossed the zenith; at Warrington, which is further south, the culminating point of the arch was north of the zenith. Wherever seen, the arch always seemed to terminate nearly in the magnetic, east and west, at two opposite points of the horizon. The observations, in which the author places the greatest confidence for determining the height of this aurora, were those made at Whitehaven and at Warrington, places which are distant 83 miles from one another, and situated nearly on the same magnetic meridian. Calculating from the data they afford, he finds the height of the arch very nearly 100 miles above the surface of the earth, and immediately over the towns of Kendal and of Kirkby-Stephen. This conclusion is corroborated by observations at Jedburgh; but if the former be compared with those at Edinburgh, the height will come out to be 150 or 160 miles, and the position vertical about Carlisle: but he thinks the former result more entitled to confidence. Assuming the height to be 100 miles, it will follow that the breadth of the arch would be 8 or 9 miles, and its visible length in an east and west direction from any one place would be about 550 miles. The author then proceeds to take a comparative view of the results of inquiries on the height and position of other auroræ which have at different times appeared, and are recorded in the Philosophical Transactions and other scientific journals. He also gives an account of a luminous arch seen both at Kendal and at Manchester on the 27th of December last, which appeared in the zenith at the former place, and was elevated 53° from the north at the latter place; whence its height is deduced to be 100 miles. From the general agreement of this series of observations, the author infers that these luminous arches of the aurora, which are occasionally seen stretching from east to west, are all nearly of the same height; namely, about 100 miles. Observations are still wanting for the determination of the length of beams parallel to the dipping-needle, which constitute the more ordinary forms of the aurora borealis; neither can it be determined whether these beams arise above the arches, as from a base, or whether they descend below, as if appended to the arches. It is remarkable that the arches and beams are rarely, if ever, seen connected together, or in juxta-position; but always in parts of the heavens at a considerable distance from each other.

Palmyra under the Aegis of Rome

1963 ◽  
Vol 53 (1-2) ◽  
pp. 43-54 ◽  
Author(s):  
I. A. Richmond
Keyword(s):  
Persian Gulf ◽  
Geographical Isolation ◽  
Political Influences ◽  
The North ◽  
Intimate Knowledge ◽  
East And West ◽  
The Cross ◽  
The Persian Gulf

In the most southerly group of desert routes between Syria and Mesopotamia Palmyra lies at the cross-roads. The north-eastward route from Damascus to Circesium is crossed by the eastward route from Emesa, now Homs, to Babylonia. Palmyra owes this key-position first to its precious springs and secondly to the fact that here the natural traffic lines from west to east debouch from the Syrian mountains into the head of the eastwardlooking basin of the Wadi el Khorr, a winter tributary of the Euphrates. Nor were these obvious routes the sole possibility. At Circesium the Euphrates may be crossed: at its eastward turn the lower river and its valley-dwellers become dominant—here runs the modern frontier between Syria and Iraq. Avoiding this control, caravan routes, negotiable solely by those with intimate knowledge of the waste and its people, lead direct to the heart of Mesopotamia and onwards to the Persian Gulf. As between East and West, Palmyra, an island in the desert, offered both a mart for exchange and an essential staging-point for direct through traffic. Its possessors were by nature masters of the situation; and, while they might be subject to the cultural or political influences of either East or West, their geographical isolation secured for them an independence founded upon pre-eminent experience of desert ways, which constituted them the natural masters and middlemen of the caravan routes that met and branched or crossed in their oasis.

scholarly journals Climate change in the western Antarctic Peninsula since 1945: observations and possible causes

1998 ◽  
Vol 27 ◽  
pp. 571-575 ◽  
Author(s):  
J. C. King ◽  
S. A. Harangozo
Keyword(s):  
Sea Ice ◽  
Atmospheric Circulation ◽  
Antarctic Peninsula ◽  
The West ◽  
Sea Ice Extent ◽  
The North ◽  
Ultimate Cause ◽  
Temperature Records ◽  
High Level ◽  
The Antarctic

Temperature records from slations on the west roast of the Antarctic Peninsula show a very high level of interannual variability and, over the last 50 years, larger warming trends than are seen elsewhere in Antarctica. in this paper we investigate the role of atmospheric circulation variability and sea-ice extent variations in driving these changes. Owing to a lack of independent data, the reliability of Antarctic atmospheric analyses produced in the 1950s and 1960s cannot be readily established, but examination of the available data suggests that there has been an increase in the northerly component of the circulation over the Peninsula since the late 1950s. Few observations of sea-ice extent are available prior to 1973, but the limited data available indicate that the ice edge to the west of the Peninsula lay to the north of recently observed extremes during the very cold conditions prevailing in the late 1950s. The ultimate cause of the atmospheric-circulation changes remains to be determined and may lie outside the Antarctic region.

scholarly journals Courage and Cowardice in the North African Campaign: The Eighth Army and Defeat in the Summer of 1942

2013 ◽  
Vol 20 (1) ◽  
pp. 99-122 ◽  
Author(s):  
Jonathan Fennell
Keyword(s):  
North Africa ◽  
The State ◽  
The Other ◽  
Human Dimension ◽  
North African ◽  
The North ◽  
High Level ◽  
Eighth Army

High rates of desertion and surrender during the battles in North Africa in the summer of 1942 were a major factor in Eighth Army’s poor combat performance. At the time, some suggested that these problems were symptomatic of a lack of courage or even of cowardice. There are two broad strands to the conceptualization of courage and cowardice. One focuses on the willingness of the person to fight; the other puts emphasis on how actions express an individual’s ability to cope with fear. Whichever conceptualization is used, high morale motivates the soldier to fight and shields the ordinary recruit from his fear, preventing it from overcoming him in battle. Where morale fails, the soldier is left demotivated and burdened with his terror and, therefore, and is therefore prone to desertion or surrender. Because it is extremely difficult to maintain morale at a continuously high level in an environment governed by chance and managed by humans, all soldiers can find themselves in situations where their actions may be judged as cowardly. Alternatively, if they are properly motivated to fight and prepared by the state and military to deal with the unavoidable fear of combat, all soldiers can be labelled courageous. Accordingly, emotive terms should be avoided when attempting to describe rationally explainable outcomes. The undoubtedly negative connotations attached to cowardice in battle and the positive ones attached to courage are, therefore, arguably unhelpful in understanding Eighth Army’s performance in the summer of 1942 and the human dimension in warfare more generally.

Floral diversity, phytogeography, and climatic amelioration during the Early Carboniferous (Dinantian)

Paleobiology ◽  
1985 ◽  
Vol 11 (3) ◽  
pp. 293-309 ◽  
Author(s):  
Anne Raymond
Keyword(s):  
Plant Diversity ◽  
Early Carboniferous ◽  
High Latitudes ◽  
New Genera ◽  
Generic Level ◽  
The North ◽  
Floral Diversity ◽  
High Level ◽  
In The Beginning

Phytogeographic analysis of three Early Carboniferous intervals (Tournaisian–early Visean, Visean, and late Visean–early Namurian A) indicates a high level of phytogeographic differentiation in the beginning of the Early Carboniferous that decreases toward the end of this period. Climatic amelioration (warmer or wetter conditions) in the north middle and high latitudes, caused by the collision of Laurussia and Gondwana at the end of the Early Carboniferous, may be responsible for this decrease in phytogeographic provinciality. Toward the end of the Early Carboniferous, a large number of equatorial genera expand their ranges northward, and the average generic diversity of assemblages in the north high latitudes (Siberia) also rises. Both support the hypothesis of climatic amelioration. Northward migration of equatorial forms and the appearance of new genera endemic to Siberia both contributed to the rise in Siberian diversity. Although this trend is not statistically significant, additional evidence of diversity increase in northern high latitudes tied to climatic amelioration comes from the northernmost limit of diverse (≥ 10 genera) assemblages, which rises from 20°N at the beginning to 55°N at the end of the Early Carboniferous. Global plant diversity assessed at the generic level remained constant during the Early Carboniferous. The increase in Siberian diversity was offset by a decrease in equatorial diversity, perhaps due to the loss of pronounced latitudinal climatic gradients between north-middle and equatorial latitudes.

scholarly journals The prediction of tsunami travel time to Mataram City Indonesia based on North Lombok earthquake as the initial condition

2018 ◽  
Vol 229 ◽  
pp. 04007
Author(s):  
Eko Pradjoko ◽  
Lukita Wardani ◽  
Hartana ◽  
Heri Sulistiyono ◽  
Syamsidik
Keyword(s):  
Travel Time ◽  
Earthquake Hazard ◽  
Capital City ◽  
Maximum Magnitude ◽  
Initial Condition ◽  
Tsunami Simulation ◽  
The Past ◽  
The North ◽  
Tsunami Travel Time ◽  
High Level

The past earthquake records in North Lombok show the high level of earthquake hazard in this area. The maximum magnitude of the earthquake was 6.4 Mw on May 30th, 1979. But, there were no tsunami events records due to those earthquakes. Nevertheless, this area is very close to Mataram City (province capital city) and tourism area. Therefore, the assessment of tsunami hazard is very important. The tsunami simulation was conducted by using COMCOT Model, which is based on the North Lombok Earthquake as the initial condition. The simulation result shows the prediction of tsunami travel time is about 18 ~ 20 minutes from the source location to Mataram City. The height of the tsunami wave is 0.13 ~ 0.20 meters due to the earthquake magnitude is about 6 Mw.

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