scholarly journals The Esophageal Adenocarcinoma Epidemic Has Reached Hungary: A Multicenter, Cross-Sectional Study

2020 ◽  
Vol 10 ◽  
Author(s):  
Benedek Tinusz ◽  
László Botond Szapáry ◽  
Bence Paládi ◽  
András Papp ◽  
Barna Bogner ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cell Cancer ◽  
Cross Sectional Study ◽  
Linear Regression Models ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Histological Types ◽  
Relative Incidence ◽  
Significant Difference

BackgroundThe epidemiology of esophageal cancer has changed dramatically over the past 4 decades in many Western populations. We aimed to understand the Hungarian epidemiologic trends of esophageal squamous cell cancer (SCC) and adenocarcinoma (AC).MethodsWe performed a cross-sectional study using data from esophageal cancer patients diagnosed between 1992 and 2018 at eight tertiary referral centers in four major cities of Hungary. We retrospectively identified cases in the electronic databases of each center and collected data on gender, age at diagnosis, year of diagnosis, specialty of the origin center, histological type, and localization of the tumor. Patients were grouped based on the two main histological types: AC or SCC. For statistical analysis, we used linear regression models, chi-square tests, and independent sample t tests.ResultsWe extracted data on 3,283 patients with esophageal cancer. Of these, 2,632 were diagnosed with either of the two main histological types; 737 had AC and 1,895 SCC. There was no significant difference in the gender ratio of the patients between AC and SCC (80.1 vs 81.8% males, respectively; p = 0.261). The relative incidence of AC increased over the years (p < 0.001, b = 1.19 CI: 0.84–1.54). AC patients were older at diagnosis than SCC patients (64.37 ± 11.59 vs 60.30 ± 10.07 years, p < 0.001). The age of patients at the diagnosis of primary esophageal cancer increased over time (p < 0.001, R = 0.119).ConclusionsThe rapid increase in the relative incidence of AC and simultaneous decrease of the relative incidence of SCC suggest that this well-established Western phenomenon is also present in Hungary.

scholarly journals Denver Developmental Screening Test in two-year old infants delivered by vacuum extraction

2017 ◽  
Vol 41 (1) ◽  
pp. 27
Author(s):  
Meriah Sembiring ◽  
Iskandar Iskandar ◽  
Amir Syarifuddin ◽  
Bistok Saing
Keyword(s):  
Physical Examination ◽  
Screening Test ◽  
Cross Sectional Study ◽  
Developmental Screening ◽  
Vacuum Extraction ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Developmental Retardation ◽  
Significant Difference

The aim of this study was to determine the developmental retardation of infants of two years of age who were delivered by vacuum extraction. This cross-sectional study examined 44 infants delivered by vacuum extraction, comprising 25 males and 19 females who were born in Tembakau Deli and St. Elizabeth Hospitals, between August 1993 until February 1994. The examination included interview and physical examination in the patient's house. Chi-square statistics analysis was used with a significant level of 95% (1'=0.05). The results showed Ihat of the 44 infants delivered by vacuum extraction. 28 (32%) had had were found with mild asphyxia, while 2 infants (5%). whose mothers work as private clerk and entrepreneur, had development retardation. We concluded that there was no significant difference in development between infants delivered by vacuum extraction and those who were born spontaneously. Developmental retardation was found in infants whose mothers lack time to communicate.

scholarly journals Position of lips and tongue in rest in newborns with and without ankyloglossia

CoDAS ◽  
2021 ◽  
Vol 33 (6) ◽  
Author(s):  
Silvia Márcia Andrade Campanha ◽  
Roberta Lopes de Castro Martinelli ◽  
Durval Batista Palhares
Keyword(s):  
Visual Inspection ◽  
Cross Sectional Study ◽  
University Hospital ◽  
Sectional Study ◽  
Hospital Data ◽  
Chi Square ◽  
Cross Sectional ◽  
Significance Level ◽  
Significant Difference ◽  
Chi Square Test

ABSTRACT Purpose Verify the position of lips and tongue at rest in newborns with and without ankyloglossia. Methods Cross-sectional study, carried out with 130 newborns in University Hospital. Data collection was performed by the researcher and speech-language pathologists from the Hospital. Information on gestational age, sex, weight, height and days of life was collected. The position of the lips and tongue at rest was evaluated through visual inspection with the newborns asleep. After the newborns were awakened, Neonatal Screening of the validated Protocol for the evaluation of the lingual frenulum for infants was performed to detect the alteration of the lingual frenulum. The data obtained were described and submitted to statistical analysis using the Chi-Square test to verify the association between the position of the lips with the tongue and to compare the position of the lips and tongue with and without ankyloglossia. The Mann-Whitney test was used to verify the behavior of the variables the differed between newborns with and without ankyloglossia. The significance level of 5% was adopted. Results When comparing the data, a significant difference was found between: weight and height with and without ankyloglossia; position of lips and tongue. An association between the position of the tongue and lips with and without ankyloglossia was also found. Conclusion Newborns without alteration of the lingual frenulum have a tendency to remain with their lips closed and their tongue elevated during rest and newborns with ankyloglossia have a tendency to keep their lips parted and their tongue low during rest.

scholarly journals A Cross-Sectional Study of Antibiotic Self-Medication

Thrita ◽  
2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Fatemeh Mousavi ◽  
Parisa Shojaei ◽  
Azadeh Nazemi ◽  
Atefe Dadashi
Keyword(s):  
Logistic Regression ◽  
Side Effects ◽  
Cross Sectional Study ◽  
Study Data ◽  
P Value ◽  
Sectional Study ◽  
Self Medication ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference

Objectives: This research has been conducted to study antibiotic self-medication, prevalence, and reasons. Methods: A questionnaire containing 30 comprehensive questions in terms of the experience of antibiotic self-medication was prepared. In this cross-sectional study, data were analyzed using analytical statistics bases on chi-square and logistic regression. Results: The results showed that 61.3% of the participants were self-antibiotic users. There was a significant difference only between gender and self-medication such that self-medication in males was more than females (P value = 0.027). Conclusions: Self-medication of antibiotics is almost high and requires more information about the side effects of these drugs in order to promote rational and physically prescribed use.

scholarly journals Dentogingival Smile Analysis of Young Adults of Al Qassim Province, Saudi Arabia: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Minu P. Mohan ◽  
Rahaf A. AlOlayan ◽  
Mohammad A. AlSweed
Keyword(s):  
Young Adults ◽  
Saudi Arabia ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Lower Lip ◽  
Restorative Treatment ◽  
Significant Difference ◽  
Photo Editing

Objectives. The present study aims to analyse the smiling components among young adults within Al Qassim region by evaluating typical smile parameters. Methodology. A cross-sectional study was conducted among 324 female and male participants between 18 and 35 years, within Al Qassim Province of Saudi Arabia. The dentogingival macro-aesthetic elements of the smile, the parallelism between the incisal curve and lower lip line, midline, and buccal corridors were determined by using Canon Rebel t7i (Canon, Melville, NY, USA) and evaluated by photo editing software Adobe Photoshop CC2019. The data were analysed using a chi-square test and Spearman’s correlation test for nonparametric data. Results. 62.5% of young adults had no buccal corridors. The nonparallel smile was found in 53.2% of young adults. A high smile line was observed in 33% of participants. 59.3% of young adults lacked a coinciding dental and facial midline. There was a statistically significant difference in the parallelism of the incisal curve and lower lip line as well as in the position of the upper lip line across genders ( P < 0.05 ). Conclusion. Understanding macro-aesthetic elements of teeth and their interrelation with the surrounding oral structures can be a guide in creating natural and aesthetically pleasing restorative treatment.

scholarly journals CYP1A2 Gene Polymorphism and Theophylline Level in Asthma

2019 ◽  
Vol 11 (1) ◽  
pp. 63-9
Author(s):  
Amelia Lorensia ◽  
Zullies Ikawati ◽  
Tri Murti Andayani ◽  
Daniel Maranatha ◽  
Mariana Wahyudi
Keyword(s):  
Gene Polymorphism ◽  
Gene Polymorphisms ◽  
Asthma Exacerbation ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Theophylline Level ◽  
Significant Difference ◽  
Polymorphism Data

BACKGROUND: Aminophylline (theophylline) is one of the most frequent asthma therapies in Indonesia, although it remains as a narrow therapy. The effects of drugs are individualized and strongly influenced by genetic, one of which is CYP1A2 gene polymorphisms. This study aimed to determine the profile of CYP1A2 polymorphism and theophylline level in asthma exacerbation patients receiving intravenous aminophylline therapy.METHODS: This cross sectional study was conducted in the emergency room (ER), to adults asthma exacerbation patients without complication (n=27), visiting the ER. The gene polymorphism data were compared with theophylline levels in the blood using chi-square test.RESULTS: In the CYP1A2 gene polymorphism profile, the most common heterozygous alleles are T/G genotype of CYP1A2*1E and C/A genotype of CYP1A2*1F. Most homozygote alleles exist in CYP1A2*1D and CYP1A2*1F. There was significant difference between CYP1A2*1D (p<0.005), CYP1A2*1E (p<0.023) and CYP1A2*1F (p<0.000) polymorphisms and theophylline level.CONCLUSION: CYP1A2*1D, CYP1A2*1E and CYP1A2*1F gene polymorphisms had an effect on theophylline levels. However, no one experienced an overdose theophylline, and no correlation between theophylline levels with CYP1A2 gene polymorphism.KEYWORDS: exacerbation asthma, intravenous aminophylline, CYP1A2 polymorphism gene, theophylline

scholarly journals Interproximal contact areas of primary molars based on OXIS classification – a two centre cross sectional study

2021 ◽  
Vol 5 ◽  
pp. 285
Author(s):  
Tarun Walia ◽  
M Kirthiga ◽  
Carel Brigi ◽  
M S Muthu ◽  
Ruba Odeh ◽  
...  
Keyword(s):  
Research Question ◽  
Cross Sectional Study ◽  
Permanent Teeth ◽  
Primary Molars ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Contact Areas ◽  
Significant Difference ◽  
Chi Square Test

Background: Contact areas in primary teeth are known to be broader, flatter and situated farther gingivally than permanent teeth. The purpose of this study was to assess the prevalence of OXIS contact areas between primary molars using die models of children from two different ethnic populations. The research question of the present study is “What is the prevalence OXIS contact areas of primary molars in the populations studied?”. Methods: A cross-sectional study was planned in a representative sample of 200 caries-free contact areas among children aged 3-6 years in two centers, Ajman and Puducherry. Data collection was performed from sectional or full-arch die stone models. The contacts were assessed according to OXIS classification by a single calibrated examiner at Center 2. Prevalence was expressed as numbers and percentages. The Chi-square test was applied to determine the association of OXIS contacts across genders and arches. Results: The prevalence of O, X, I, and S contacts were 19%, 22.5%, 53%, and 5.5% in Center 1 and 6%, 1.5%, 75.5%, and 17% in Center 2, respectively. Significant results (p=0.005) were obtained in Center 1 when inter-arch comparison was performed and between the centers with respect to type of contact. No significant difference was obtained with respect to gender and OXIS contact areas. Conclusions: The present study confirmed OXIS contacts in both the centers. The ‘O’ and ‘X’ types of contacts were observed more in Center 1, whereas ‘I’ and ‘S’ contacts were observed more in Center 2.

scholarly journals Obesitas dan hubungannya dengan polimorfisme gena promoter 5-HT2A, tekanan darah, profil lipid, kadar glukosa, dan malondialdehid

2011 ◽  
Vol 8 (2) ◽  
pp. 81
Author(s):  
Pramudji Hastuti ◽  
Nur Anisah ◽  
Johan Iswara Siagian ◽  
Kautsar Prastudia Eko Binuko ◽  
Aidil Adhla
Keyword(s):  
Blood Pressure ◽  
Cross Sectional Study ◽  
Lipid Profiles ◽  
Obese Group ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference ◽  
Or Gene ◽  
And Gender

Background: Obesity among adults has risen significantly in the world-cutting across all ages, racial and ethnic groups and gender. The 5-HT 2A receptor is crucially involved in regulation of body weight and the appetite. Disturbances in the distribution and or gene regulation of the postsynaptic 5-HT2A receptor are implicated in the pathophysiology of conditions such as obesity, coronary heart disease, high blood pressure, diabetes, stroke dan some cancers.Objective: To test the association between obesity with polymorphism of promoter -1438G→A 5-HT2A receptors gene, blood pressure, lipid profiles, levels of blood glucose and malondialdehyde (MDA).Method: This cross-sectional study included thirty six unrelated obese young people (BMI ≥ 30) recruited from populations in Yogyakarta and 36 controls with age matched with BMI ≤ 25. Statistical differences between blood pressure, lipid profiles, glucose and MDA levels were assessed by t-test and genotypes by Chi square test.Results: There were no significant difference in blood pressure lipid profile, level of glucose and MDA in obese group compared with control (p>0,05). Allele A and G frequency in obese group 25% and 75% respectively, and controls 22.2% and 77.8% respectively, and no significant difference in all two groups, but G allele had higher risk to obese than A allele.Conclusion: These data indicated G allele was mild risk factor for obesity.

scholarly journals Viral clearance in COVID-19 patients admitted in designated COVID hospital in Western India

2021 ◽  
Vol 8 (9) ◽  
pp. 4303
Author(s):  
Harpreet Singh ◽  
Kanwaljit Kaur ◽  
S. K. Ghai ◽  
Pranaya Gurmeet ◽  
Raju Agarwal ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Cross Sectional Study ◽  
Viral Clearance ◽  
Care Hospital ◽  
Sectional Study ◽  
Rt Pcr ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference ◽  
Chi Square Test

Background: COVID-19 pandemic is one of the greatest challenges faced worldwide and has not only posed health crisis but also had social, economic and political devastating effects. The speedy transmission risk enforced bygone practices of quarantine of healthy persons and isolation of all positive patients. The basis of all key policy making is the understanding of virus clearance from the body so that transmission can be ceased. The aim of the study was to understand the viral clearance and its’ co-relates for guiding infection control and transmission practices in COVID-19.Methods: Cross sectional study in a tertiary care hospital. A cross-sectional study of total 398 patients admitted for COVID-19 between June 2020 and November 2020 at a tertiary care centre. Statistical analysis used: frequency, percentage, and chi square test Chi square test for linear trend and was used to find association.Results: 88.19% were males and 11.81% were female patients, mean age of study participants was 34.84 years. 61.56% were symptomatic and among them 1.64% presented with severe symptoms. Mean duration to turn RT-PCR negative was 11.83 days. No significant difference in time taken to turn RT-PCR negative among asymptomatic and symptomatic cases is suggestive of no difference in viral load and its clearance in symptomatic vs asymptomatic cases.Conclusions: The disease profile of COVID-19 in our setup was alike the national disease profile and the recovery rate being 98.76%. Presence of co-morbidities affects viral clearance in COVID-19.

scholarly journals OXIS contact areas of primary molars – a two center cross-sectional study

2020 ◽  
Vol 5 ◽  
pp. 285
Author(s):  
Tarun Walia ◽  
M Kirthiga ◽  
Carel Brigi ◽  
M S Muthu ◽  
Ruba Odeh ◽  
...  
Keyword(s):  
Research Question ◽  
Cross Sectional Study ◽  
Permanent Teeth ◽  
Primary Molars ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Contact Areas ◽  
Significant Difference ◽  
Chi Square Test

Background: Contact areas in primary teeth are known to be broader, flatter and situated farther gingivally than permanent teeth. The purpose of this study was to assess the prevalence of OXIS contact areas between primary molars using die models of children from two different ethnic populations. The research question of the present study is “What is the prevalence OXIS contact areas of primary molars in the populations studied?”. Methods: A cross-sectional study was planned in a representative sample of 200 caries-free contact areas among children aged 3-6 years in two centers, Ajman and Puducherry. Data collection was performed from sectional or full-arch die stone models. The contacts were assessed according to OXIS classification by a single calibrated examiner at Center 2. Prevalence was expressed as numbers and percentages. The Chi-square test was applied to determine the association of OXIS contacts across genders and arches. Results: The prevalence of O, X, I, and S contacts were 19%, 22.5%, 53%, and 5.5% in Center 1 and 6%, 1.5%, 75.5%, and 17% in Center 2, respectively. Significant results (p=0.005) were obtained in Center 1 when inter-arch comparison was performed and between the centers with respect to type of contact. No significant difference was obtained with respect to gender and OXIS contact areas. Conclusions: The present study confirmed OXIS contacts in both the centers. The ‘O’ and ‘X’ types of contacts were observed more in Center 1, whereas ‘I’ and ‘S’ contacts were observed more in Center 2.

scholarly journals Vitamin D Deficiency and Psoriasis: A Cross-Sectional study of Iranian Population in Yazd Province

2020 ◽  
Author(s):  
Mohammad Ebrahimzadeh Ardakani ◽  
Mohammad Afkhami-Ardekani ◽  
Mohammad Reza Taghizadeh Yazdi ◽  
Nasim Namiranian ◽  
Farideh Radmehr
Keyword(s):  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Hypovitaminosis D ◽  
Serum Levels ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Significant Difference

Objective: Psoriasis is an inflammatory disease of the skin and the joints. Psoriatic patients sometimes suffer from vitamin D deficiency and hypocalcemia. The aim of our study was to evaluate the level of calcium and vitamin D in patients with psoriasis. Materials and Methods: In this analytical cross sectional study, 110 cases of psoriasis that were referred to Shohadaye Mehrab clinic during 2015 and 110 non-psoriatic patients enrolled. Serum levels of calcium, phosphorus, parathyroid hormone (PTH), alkaline phosphatase (ALK) and 25- hydroxy vitamin D3 [(25OH) D3] were measured in both groups. Data were analyzed using SPSS software version 19. Chi square test and T-test were used for statistical analysis. Results: Among110 patients with psoriasis 74 (67.3%) were men and 36 (32.75%) were women. There was no significant difference in the serum level of calcium (P-value: 0.563), phosphorus (P-value: 0.381), PTH (P-value: 0.364) and ALK (P-value: 0.639) between two groups. Vitamin D deficiency was found in 64.5% of psoriatic patients and 60% of the controls (P-value= 0.45); However 30.9% of psoriatic and 17.3% of the controls suffered from severe hypovitaminosis D. This difference was statistically significant (Pvalue= 0.014).Conclusion: We found a significant relationship between severe hypovitaminosis D and psoriasis. This finding revealed the need for evaluation of psoriatic patients for the presence of vitamin D deficiency.

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