scholarly journals The Importance of Alexithymia in Post-surgery. Differences on Body Image and Psychological Adjustment in Breast Cancer Patients

2020 ◽  
Vol 11 ◽  
Author(s):  
Lorena Gutiérrez Hermoso ◽  
Lilian Velasco Furlong ◽  
Sofía Sánchez-Román ◽  
Lorena Salas Costumero
Keyword(s):  
Breast Cancer ◽  
Body Image ◽  
Psychological Adjustment ◽  
Radical Mastectomy ◽  
Breast Conserving Therapy ◽  
Self Report ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Post Surgery ◽  
Type Of Surgery

Breast cancer is a disease that is difficult to face and that often hinders body acceptance. Body changes due to surgery can be very emotionally challenging for those who experience them. The aim of this study is to explore the differences on body image and psychological adjustment on women with breast cancer with high and low alexithymia according to the type of surgery. In this cross-sectional study, 119 women diagnosed with breast cancer (stages I, II, and III) were evaluated with different self-report questionnaires. Afterward, patients were divided into two groups (high and low levels of alexithymia) to analyze dependent variables (body image and psychological adjustment) according to the type of surgery (radical mastectomy or breast conserving therapy). The results of the General Linear Model suggest that when patients show high alexithymia combined with having undergone a radical mastectomy, they show higher levels of Hopelessness. Furthermore, in patients with high alexithymia, higher scores of maladaptive coping styles and greater distortion of body image were found. Alexithymia seems to play an important role in the way in which women cope with their disease, especially in those with radical mastectomy.

Radical Mastectomy Increases Psychological Distress in Young Breast Cancer Patients: Results of A Cross-sectional Study

2019 ◽  
Vol 19 (1) ◽  
pp. e160-e165 ◽  
Author(s):  
Soufiane Berhili ◽  
Asmae Ouabdelmoumen ◽  
Ali Sbai ◽  
Tayeb Kebdani ◽  
Noureddine Benjaafar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Psychological Distress ◽  
Cancer Patients ◽  
Radical Mastectomy ◽  
Cross Sectional Study ◽  
Breast Cancer Patients ◽  
Sectional Study ◽  
Cross Sectional ◽  
Young Breast Cancer

scholarly journals Association between cancer stigma, pain and quality of life in breast cancer

2020 ◽  
Vol 8 (1) ◽  
pp. 275-287
Author(s):  
Ora Nakash ◽  
Leeat Granek ◽  
Michal Cohen ◽  
Merav Ben David
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Pain Intensity ◽  
Self Report ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Convenience Sample ◽  
Cross Sectional Design ◽  
The Impact

Aim We examined the association between cancer stigma and quality of life. We further explored the role of pain intensity in this association among women with breast cancer in the first months following diagnosis. Methods 105 women with breast cancer within 8 months of diagnosis completed self-report measures assessing cancer stigma, pain intensity and quality of life. Results Our findings show that stigma among breast cancer patients is associated with worse quality of life. Pain intensity partially mediated the relationship between cancer stigma and quality of life. We recruited a convenience sample of women with breast cancer, which may be subject to selection bias. The cross sectional design of the study precludes inferences regarding causality. Conclusions Health professionals should recognize and mitigate the impact of stigma as an important factor that is associated with impaired quality of life among patients with breast cancer. Continued attention should be paid to pain intensity and the complex relationship between stigma and pain in predicting quality of life.

Factors affecting type of surgical treatment in patients with breast cancer

2009 ◽  
Vol 27 (15_suppl) ◽  
pp. e20633-e20633
Author(s):  
M. Garip ◽  
M. Gumus ◽  
F. Dane ◽  
M. Seker ◽  
A. Bilici ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Surgery ◽  
Radical Mastectomy ◽  
Breast Conserving Surgery ◽  
Clinicopathological Characteristics ◽  
Age At First Birth ◽  
Breast Cancer Patients ◽  
Factors Affecting ◽  
Nulliparous Women ◽  
Type Of Surgery

e20633 Background: Many prospective randomized studies have shown that modified radical mastectomy (MRM) and breast conserving surgery (BCS) are equivalent in terms of overall survival. Patients’ social and cultural features and clinicopathological characteristics of the tumors generally influence the decision of selecting surgical type. Here, we aimed to evaluate the variables that affect the type of surgical resection in our patients’ population. Methods: One hundred patients undergone breast surgery with the diagnosis of breast cancer from December 2007 to March 2008 were included in the study. After detailed history taking and physical examination, all patients were given questionnaire evaluating sociodemographical data and parameters influencing their decision in choosing type of breast surgery. Results: Overall, 100 patients (80 MRM, 20 BCS) were evaluated in this study. Age was statistically significant predictive indicator in choosing BCS (p: 0.025). Nulliparous women were more likely to select BCS than multiparous (p:0,004). Patients who have the experience of breastfeeding less likely preferred BCS (p: 0.007). Having taken second opinion from a different breast surgeon about type of surgery during evaluation made patients select more BCS (p: 0.023). Although not statistically significant patients who had family history of breast cancer had selected MRM more than BCS (p: 0.088). Marital status, life assurance, age at first birth, and education status were not associated with the decision of selecting type of surgery. Conclusions: We concluded that cosmetic concern and risk of relapse affect the decision of surgical type in breast cancer patients. Broader efforts should be made to inform our patients about the results of BCS. No significant financial relationships to disclose.

scholarly journals Đánh giá chất lượng cuộc sống bệnh nhân ung thư vú sau phẫu thuật

2020 ◽  
Author(s):  
Đức Thành Nguyễn
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patients ◽  
Social Factor ◽  
Radical Mastectomy ◽  
Age Group ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
The Mean

EVALUATION QUALITY OF LIFE BREAST CANCER PATIENTS POST – OPERATIVE Objective: This descriptive and cross-sectional study quality of life breast cancer postoperative (include both mastectomy and Breast conserving surgery) and dertermine social factors related to quality of life breast cancer postoperative. Method: We collected 60 patients of carcinoma breast cancer post modified radical mastectomy. They were interviewed directly through questionnaires on quality of life of EORTC QLQ C-30. Results: The results showed that the mean age at this study was 47,6 years. Younger women in age group 30-39 years had faird worst on physical, social, and emotional scores as compare to older women in the age group of 70-79 years. Conclusion: The mean socres quality of life of patients with breast cancer postoperative at Thai Nguyen Oncology Center was differencebetween younger patient (30-39) years and older paient (70-79) years. In addition, Age and education status on this study were factor which related to quality of life in Breast Cancer Patients. Keywords: Breast cancer, Quality of life, social factor

Association of CYP2D6*10 (c. 100 C>T) Genotype with Z-END Concentration in Patients with Breast Cancer Receiving Tamoxifen Therapy in Indonesian Population

2019 ◽  
Vol 19 (8) ◽  
pp. 1198-1206 ◽  
Author(s):  
Yenny ◽  
Sonar S. Panigoro ◽  
Denni J. Purwanto ◽  
Adi Hidayat ◽  
Melva Louisa ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Steady State ◽  
Ultra Performance Liquid Chromatography ◽  
Cross Sectional Study ◽  
Threshold Concentration ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Significant Difference ◽  
Pcr Rflp ◽  
Liquid Chromatography Tandem Mass

Background: Tamoxifen (TAM) is a frequently used hormonal prodrug for patients with breast cancer that needs to be activated by cytochrome P450 2D6 (CYP2D6) into Zusammen-endoxifen (Z-END). Objective: The purpose of the study was to determine the association between CYP2D6*10 (c.100C>T) genotype and attainment of the plasma steady-state Z-END minimal threshold concentration (MTC) in Indonesian women with breast cancer. Methods: A cross-sectional study was performed in 125 ambulatory patients with breast cancer consuming TAM at 20 mg/day for at least 4 months. The frequency distribution of CYP2D6*10 (c.100C>T) genotypes (C/C: wild type; C/T: heterozygous mutant; T/T: homozygous mutant) was detected using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP), the results of which were subsequently confirmed by sequencing. The genotypes were categorized into plasma Z- END concentrations of <5.9 ng/mL and ≥5.9 ng/mL, which were measured using ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). Results: Percentages of C/C, CT, and T/T genotypes were 22.4%, 29.6%, and 48.8%, respectively. Median (25-75%) Z-END concentrations in C/C, C/T, and T/T genotypes were 9.58 (0.7-6.0), 9.86 (0.7-26.6), and 3.76 (0.9-26.6) ng/mL, respectively. Statistical analysis showed a significant difference in median Z-END concentration between patients with T/T genotype and those with C/C or C/T genotypes (p<0.001). There was a significant association between CYP2D6*10 (c.100C>T) genotypes and attainment of plasma steady-state Z-END MTC (p<0.001). Conclusion: There was a significant association between CYP2D6*10 (c.100C>T) and attainment of plasma steady-state Z-END MTC in Indonesian breast cancer patients receiving TAM at a dose of 20 mg/day.

Overexpression of microRNA-21 in the Serum of Breast Cancer Patients

MicroRNA ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 58-63
Author(s):  
Batool Savari ◽  
Sohrab Boozarpour ◽  
Maryam Tahmasebi-Birgani ◽  
Hossein Sabouri ◽  
Seyed Mohammad Hosseini
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Cancer Progression ◽  
Tumor Resection ◽  
Tumor Grade ◽  
Healthy Controls ◽  
Breast Cancer Patients ◽  
Serum Samples ◽  
Post Surgery ◽  
Polymerase Chain

Background: Breast cancer is the most common cancer diagnosed in women worldwide. So it seems that there's a good chance of recovery if it's detected in its early stages even before the appearances of symptoms. Recent studies have shown that miRNAs play an important role during cancer progression. These transcripts can be tracked in liquid samples to reveal if cancer exists, for earlier treatment. MicroRNA-21 (miR-21) has been shown to be a key regulator of carcinogenesis, and breast tumor is no exception. Objective: The present study was aimed to track the miR-21 expression level in serum of the breast cancer patients in comparison with that of normal counterparts. Methods: Comparative real-time polymerase chain reaction was applied to determine the levels of expression of miR-21 in the serum samples of 57 participants from which, 42 were the patients with breast cancer including pre-surgery patients (n = 30) and post-surgery patients (n = 12), and the others were the healthy controls (n = 15). Results: MiR-21 was significantly over expressed in the serum of breast cancer patients as compared with healthy controls (P = 0.002). A significant decrease was also observed following tumor resection (P < 0.0001). Moreover, it was found that miR-21 overexpression level was significantly associated with tumor grade (P = 0.004). Conclusion: These findings suggest that miR-21 has the potential to be used as a novel breast cancer biomarker for early detection and prognosis, although further experiments are needed.

scholarly journals Complementary and Alternative Medicine Use in Breast Cancer Patients at a Medical Center in Taiwan: A Cross-Sectional Study

2020 ◽  
Vol 19 ◽  
pp. 153473542098391
Author(s):  
Chieh-Ying Chin ◽  
Yung-Hsiang Chen ◽  
Shin-Chung Wu ◽  
Chien-Ting Liu ◽  
Yun-Fang Lee ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Alternative Medicine ◽  
Complementary And Alternative Medicine ◽  
Cancer Patients ◽  
Medical Center ◽  
Cancer Center ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Cam Use ◽  
Complementary And Alternative

Background Complementary and alternative medicine (CAM) is becoming more common in medical practice, but little is known about the concurrent use of CAM and conventional treatment. Therefore, the aim was to investigate the types of CAM used and their prevalence in a regional patient cohort with breast cancer (BC). Methods BC patients were interviewed with a structured questionnaire survey on the use of CAM in southern Taiwan at an Integrative Breast Cancer Center (IBCC). The National Centre for Complementary and Integrative Health (NCCIH) classification was used to group responses. Over a period of 8 months, all patients receiving treatment for cancer at the IBCC were approached. Results A total of 106 BC patients completed the survey (response rate: 79.7%). The prevalence of CAM use was 82.4%. Patients who were employed, were receiving radiotherapy and hormone therapy, and had cancer for a longer duration were more likely to use CAM ( P < .05). Multivariate analysis identified employment as an independent predictor of CAM use (OR = 6.92; 95% CI = 1.33-36.15). Dietary supplementation (n = 69, 82.1%) was the type of CAM most frequently used, followed by exercise (n = 48, 57.1%) and traditional Chinese medicine (n = 29, 34.5%). The main reason for using CAM was to ameliorate the side effects of conventional therapies. Almost half (46.4%) of these CAM users did not disclose that they were using it in medical consultations with their physicians. Most chose to use CAM due to recommendations from family and friends. Conclusion A large portion of BC patients at the IBCC undergoing anti-cancer treatment courses used CAM, but less than half discussed it with their physicians. Given the high prevalence of CAM, it would be justifiable to direct further resources toward this service so that cancer patients can benefit from a holistic approach to their treatment.

The relationship of self-acceptance with decision making duration in cancer patient to perform mastectomy

2021 ◽  
pp. 1-5
Author(s):  
Ayu Ratuati Setiawan ◽  
Feny Tunjungsari ◽  
Mochamad Aleq Sander
Keyword(s):  
Breast Cancer ◽  
Decision Making ◽  
Cancer Patients ◽  
Breast Cancer Patients ◽  
Cross Sectional ◽  
Abnormal Growth ◽  
Self Acceptance ◽  
Observation Method ◽  
Relationship Of ◽  
The Relationship

BACKGROUND: Cancer is a disease caused by abnormal growth of body cells that turn malignant and continue to grow uncontrollably. One of the treatments for breast cancer is mastectomy. The quickness of decision-making determines the survival rate of prognosis patients. OBJECTIVE: This study aimed to determine the relationship of self-acceptance with decision-making duration in cancer patients to perform a mastectomy. METHODS: An analytic observation method with cross-sectional design. The samples were taken by purposive sampling method with 50 samples of breast cancer patients. Data collected include age, last level of education, marital status, profession, stage of cancer during mastectomy, self-acceptance score, and decision-making duration to perform a mastectomy. RESULTS: The data analyzed with the Kruskal–Wallis test. The test showed the relationship of self-acceptance (p = 0.027) with decision-making duration in breast cancer patients to perform a mastectomy. CONCLUSION: In Conclusion, there is a relationship of self-acceptance with decision-making duration in breast cancer patients to perform a mastectomy.

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