scholarly journals Association of Loneliness and Wisdom With Gut Microbial Diversity and Composition: An Exploratory Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Tanya T. Nguyen ◽  
Xinlian Zhang ◽  
Tsung-Chin Wu ◽  
Jinyuan Liu ◽  
Collin Le ◽  
...  
Keyword(s):  
Social Support ◽  
Linear Regression ◽  
Microbial Diversity ◽  
Gut Microbiome ◽  
Social Engagement ◽  
Alpha Diversity ◽  
Well Being ◽  
Community Dwelling ◽  
Self Report ◽  
Health And Well Being

Loneliness and wisdom have opposite effects on health and well-being. Loneliness is a serious public health problem associated with increased morbidity and mortality. Wisdom is associated with better health and well-being. We have consistently found a strong negative correlation between loneliness and wisdom. The present study aimed to investigate the association of loneliness and wisdom with the gut microbiome. One hundred eighty-four community-dwelling adults (28–97 years) completed validated self-report-based measures of loneliness, wisdom, compassion, social support, and social engagement. Fecal samples were collected and profiled using 16S rRNA sequencing. Linear regression analyses, controlling for age and body mass index, revealed that lower levels of loneliness and higher levels of wisdom, compassion, social support, and social engagement were associated with greater phylogenetic richness and diversity of the gut microbiome. Partial least squares (PLS) analysis to investigate multivariate relationships extracted two composite variables. Linear regression model predicting alpha-diversity with PLS components revealed that a linear combination of all psychosocial predictors (with negative loading for loneliness and positive loadings for all others, including wisdom, compassion, social support, and social engagement) was significantly associated with alpha-diversity. For beta-diversity, compassion and wisdom accounted for a significant proportion of variance in overall microbial community composition. Findings may have implications for interventions to reduce loneliness and possibly its health-related adverse consequences. Future research should explore whether increasing compassion and wisdom may improve loneliness and overall well-being as well as microbial diversity.

scholarly journals Evaluation of the Usability and Acceptability of the InnoWell Platform as Rated by Older Adults: Survey Study

JMIR Aging ◽  
10.2196/25928 ◽  
2021 ◽  
Vol 4 (2) ◽  
pp. e25928
Author(s):  
Haley M LaMonica ◽  
Anna E Roberts ◽  
Tracey A Davenport ◽  
Ian B Hickie
Keyword(s):  
Older Adults ◽  
Social Engagement ◽  
Later Life ◽  
Well Being ◽  
Assessment Tools ◽  
Self Report ◽  
Digital Tool ◽  
System Usability Scale ◽  
Mental Well Being ◽  
Health And Well Being

Background As the global population ages, there is increased interest in developing strategies to promote health and well-being in later life, thus enabling continued productivity, social engagement, and independence. As older adults use technologies with greater frequency, proficiency, and confidence, health information technologies (HITs) now hold considerable potential as a means to enable broader access to tools and services for the purposes of screening, treatment, monitoring, and ongoing maintenance of health for this group. The InnoWell Platform is a digital tool co-designed with lived experience to facilitate better outcomes by enabling access to a comprehensive multidimensional assessment, the results of which are provided in real time to enable consumers to make informed decisions about clinical and nonclinical care options independently or in collaboration with a health professional. Objective This study aims to evaluate the usability and acceptability of a prototype of the InnoWell Platform, co-designed and configured with and for older adults, using self-report surveys. Methods Participants were adults 50 years and older who were invited to engage with the InnoWell Platform naturalistically (ie, at their own discretion) for a period of 90 days. In addition, they completed short web-based surveys at baseline regarding their background, health, and mental well-being. After 90 days, participants were asked to complete the System Usability Scale to evaluate the usability and acceptability of the prototyped InnoWell Platform, with the aim of informing the iterative redesign and development of this digital tool before implementation within a health service setting. Results A total of 19 participants consented to participate in the study; however, only the data from the 16 participants (mean age 62.8 years, SD 7.5; range 50-72) who completed at least part of the survey at 90 days were included in the analyses. Participants generally reported low levels of psychological distress and good mental well-being. In relation to the InnoWell Platform, the usability scores were suboptimal. Although the InnoWell Platform was noted to be easy to use, participants had difficulty identifying the relevance of the tool for their personal circumstances. Ease of use, the comprehensive nature of the assessment tools, and the ability to track progress over time were favored features of the InnoWell Platform, whereas the need for greater personalization and improved mobile functionality were cited as areas for improvement. Conclusions HITs such as the InnoWell Platform have tremendous potential to improve access to cost-effective and low-intensity interventions at scale to improve and maintain mental health and well-being in later life. However, to promote adoption of and continued engagement with such tools, it is essential that these HITs are personalized and relevant for older adult end users, accounting for differences in background, clinical profiles, and levels of need.

scholarly journals Evaluation of the Usability and Acceptability of the InnoWell Platform as Rated by Older Adults: Survey Study (Preprint)

2020 ◽  
Author(s):  
Haley M LaMonica ◽  
Anna E Roberts ◽  
Tracey A Davenport ◽  
Ian B Hickie
Keyword(s):  
Older Adults ◽  
Social Engagement ◽  
Later Life ◽  
Well Being ◽  
Assessment Tools ◽  
Self Report ◽  
Digital Tool ◽  
System Usability Scale ◽  
Mental Well Being ◽  
Health And Well Being

BACKGROUND As the global population ages, there is increased interest in developing strategies to promote health and well-being in later life, thus enabling continued productivity, social engagement, and independence. As older adults use technologies with greater frequency, proficiency, and confidence, health information technologies (HITs) now hold considerable potential as a means to enable broader access to tools and services for the purposes of screening, treatment, monitoring, and ongoing maintenance of health for this group. The InnoWell Platform is a digital tool co-designed with lived experience to facilitate better outcomes by enabling access to a comprehensive multidimensional assessment, the results of which are provided in real time to enable consumers to make informed decisions about clinical and nonclinical care options independently or in collaboration with a health professional. OBJECTIVE This study aims to evaluate the usability and acceptability of a prototype of the InnoWell Platform, co-designed and configured with and for older adults, using self-report surveys. METHODS Participants were adults 50 years and older who were invited to engage with the InnoWell Platform naturalistically (ie, at their own discretion) for a period of 90 days. In addition, they completed short web-based surveys at baseline regarding their background, health, and mental well-being. After 90 days, participants were asked to complete the System Usability Scale to evaluate the usability and acceptability of the prototyped InnoWell Platform, with the aim of informing the iterative redesign and development of this digital tool before implementation within a health service setting. RESULTS A total of 19 participants consented to participate in the study; however, only the data from the 16 participants (mean age 62.8 years, SD 7.5; range 50-72) who completed at least part of the survey at 90 days were included in the analyses. Participants generally reported low levels of psychological distress and good mental well-being. In relation to the InnoWell Platform, the usability scores were suboptimal. Although the InnoWell Platform was noted to be easy to use, participants had difficulty identifying the relevance of the tool for their personal circumstances. Ease of use, the comprehensive nature of the assessment tools, and the ability to track progress over time were favored features of the InnoWell Platform, whereas the need for greater personalization and improved mobile functionality were cited as areas for improvement. CONCLUSIONS HITs such as the InnoWell Platform have tremendous potential to improve access to cost-effective and low-intensity interventions at scale to improve and maintain mental health and well-being in later life. However, to promote adoption of and continued engagement with such tools, it is essential that these HITs are personalized and relevant for older adult end users, accounting for differences in background, clinical profiles, and levels of need.

scholarly journals Endocannabinoid system mediates the association between gut-microbial diversity and anhedonia/amotivation in a general population cohort

2021 ◽  
Author(s):  
Amedeo Minichino ◽  
Matthew A. Jackson ◽  
Marta Francesconi ◽  
Claire J. Steves ◽  
Cristina Menni ◽  
...  
Keyword(s):  
General Population ◽  
Microbial Diversity ◽  
Gut Microbiome ◽  
Endocannabinoid System ◽  
Alpha Diversity ◽  
Serum Levels ◽  
Population Cohort ◽  
Random Intercept ◽  
General Population Cohort ◽  
Antidepressant Use

AbstractAnhedonia and amotivation are debilitating symptoms and represent unmet therapeutic needs in a range of clinical conditions. The gut-microbiome-endocannabinoid axis might represent a potential modifiable target for interventions. Based on results obtained from animal models, we tested the hypothesis that the endocannabinoid system mediates the association between gut-microbiome diversity and anhedonia/amotivation in a general population cohort. We used longitudinal data collected from 786 volunteer twins recruited as part the TwinsUK register. Our hypothesis was tested with a multilevel mediation model using family structure as random intercept. The model was set using alpha diversity (within-individual gut-microbial diversity) as predictor, serum and faecal levels of the endocannabinoid palmitoylethanolamide (PEA) as mediator, and anhedonia/amotivation as outcome. PEA is considered the endogenous equivalent of cannabidiol, with increased serum levels believed to have anti-depressive effects, while increased stool PEA levels, reflecting increased excretion, are believed to have opposite, detrimental, effects on mental health. We therefore expected that either reduced serum PEA or increased stool PEA would mediate the association between microbial diversity and anhedonia amotivation. Analyses were adjusted for obesity, diet, antidepressant use, sociodemographic and technical covariates. Data were imputed using multiple imputation by chained equations. Mean age was 65.2 ± 7.6; 93% of the sample were females. We found a direct, significant, association between alpha diversity and anhedonia/amotivation (β = −0.37; 95%CI: −0.71 to −0.03; P = 0.03). Faecal, but not serum, levels of the endocannabinoid palmitoylethanolamide (PEA) mediated this association: the indirect effect was significant (β = −0.13; 95%CI: −0.24 to −0.01; P = 0.03), as was the total effect (β = −0.38; 95%CI: −0.72 to −0.04; P = 0.03), whereas the direct effect of alpha diversity on anhedonia/amotivation was attenuated fully (β = −0.25; 95%CI: −0.60 to 0.09; P = 0.16). Our results suggest that gut-microbial diversity might contribute to anhedonia/amotivation via the endocannabinoid system. These findings shed light on the biological underpinnings of anhedonia/amotivation and suggest the gut microbiota-endocannabinoid axis as a promising therapeutic target in an area of unmet clinical need.

scholarly journals Meaning of Life and Well-Being: Preliminary Results of the Successful Aging Study

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 112-112
Author(s):  
Zvi Gellis ◽  
Kim McClive-Reed ◽  
Bonnie Kenaley ◽  
Eunhae Kim
Keyword(s):  
Meaning In Life ◽  
Successful Aging ◽  
Older Persons ◽  
Well Being ◽  
Community Dwelling ◽  
Life Questionnaire ◽  
Presence Of Meaning ◽  
Aging Study ◽  
Proxy Measure ◽  
Health And Well Being

Abstract Meaning in life for older persons has become a focal research point, with findings that a greater sense of meaning is associated with better outcomes on a range of health and well-being factors. Our study examined relationships between scores on several personality scales, including the Meaning in Life Questionnaire (Steger et al., 2009) and the WHO-5 Well-Being Index, a proxy measure of mood/depression. Community-dwelling members (N=535) of Osher Lifelong Learning Institutes aged 50 and up (mean age 71.4, SD = 6.93) at 3 U.S. sites completed surveys. Higher wellness levels were significantly correlated with increased resilience, optimism, life satisfaction, and presence of meaning in life, while lower levels were associated with greater searching for meaning in life. A multivariate linear regression model (F = 55.597, df = 4, p = .000, R = .566, R2 = .320) showed that wellness scores increased with higher scores in optimism (ß = .348, p =.000), resilience (ß = .183, p = .000), and presence of meaning in life (ß = .106, p = .019). However, searching for meaning in life significantly predicted decreases in wellness scores (ß = -.084, p=.019). These results support those of previous studies, suggesting that for older persons, an ongoing search for meaning in life is linked to negative outcomes than a perception of existing meaning in life. A variety of available interventions aimed at increasing meaning and purpose in life (Guerrero-Torelles et al., 2017) may contribute to better health and well-being in older adults.

The Relationship Between Physical Activity, Health, and Well-Being

2021 ◽  
Vol 28 (2) ◽  
pp. 59-70
Author(s):  
Kristine Klussman ◽  
Julia Langer ◽  
Austin Lee Nichols
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Meaning In Life ◽  
Well Being ◽  
Self Report ◽  
Community Based ◽  
Activity Intensity ◽  
Different Types ◽  
The Relationship ◽  
Health And Well Being

Abstract. Background: Most people are comfortable asserting the beneficial effects of physical exercise on mental health and well-being. However, little research has examined how different types of physical activity affect these outcomes. Aims: The current study sought to provide a comprehensive understanding of the differential relationships between different types of physical activity and various aspects of health and well-being. In addition, we sought to understand the role of self-connection in these relationships. Method: One hundred forty-three participants completed a questionnaire designed to measure their current weekly activity as well as their current health and well-being. Specifically, we examined three intensities of activity (walking, moderate, and vigorous) and three types of activity (team-based, community-based, and not team nor community-based) on self-reported health, anxiety, depression, affect, flourishing, job satisfaction, life satisfaction, and meaning in life. In addition, we examined self-connection as a possible moderator of these relationships. Results: Results suggested that physical activity was inconsistently related to health and well-being, and activity intensity and type were important to understanding these relationships. In contrast, self-connection reliably related to health and well-being and moderated the relationship between activity type and the presence of meaning. Limitations: The cross-sectional, self-report nature of the study limits its contribution. In addition, we only examined a subset of all physical activities that people engage in. Conclusion: In all, results suggest that the relationships between physical activity, mental health, and well-being are tenuous, at best. Future research needs to examine these relationships further and continue to examine self-connection to determine how to best increase health and well-being through physical activity.

Community Networks

2013 ◽  
pp. 187-207
Author(s):  
John M. Carroll ◽  
Mary Beth Rosson
Keyword(s):  
Social Engagement ◽  
Well Being ◽  
Social Boundaries ◽  
Social Milieu ◽  
The Social ◽  
Helping Others ◽  
Design Idea ◽  
Virtuous Cycle ◽  
University Undergraduates ◽  
Health And Well Being

The authors present a socio-technical design that illustrates how a community network health intervention can mobilize human resources across social boundaries and enhance health and well-being for people on both sides of the boundary. They specifically address how to reduce the barriers to social engagement experienced by autistic individuals who want more supportive life opportunities. The authors focus on the social milieu of an American college town, on traditional town-gown boundaries, and on possibilities for integrating social resources within this context. Their design adopts community networking to not only connect autistic persons living within an existing social milieu (university undergraduates; local autistic children and their families), but also to integrate individuals across milieus. The key design idea is that facilitating cross-milieu interactions can initiate and sustain a virtuous cycle of being helped by helping others.

scholarly journals DOES SEXUAL ORIENTATION RELATE TO HEALTH AND WELL-BEING? A PROPENSITY-SCORE MATCHED ANALYSIS

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S303-S303
Author(s):  
Christi L Nelson ◽  
Ross Andel
Keyword(s):  
Sexual Orientation ◽  
Propensity Score ◽  
Minority Group ◽  
Past Research ◽  
Well Being ◽  
The United States ◽  
Self Report ◽  
Psychological Well Being ◽  
Representative Study ◽  
Health And Well Being

Abstract Around 2.7 million adults over the age of 50 self-identify as lesbian, gay, bisexual, and transgender (LGBT) in the United States. Past research suggests that additional stressors caused by being a socially stigmatized minority group can have a negative effect on health and well-being. The purpose of this study was to examine the relationships between sexual orientation and self-rated health, memory, and psychological well-being in a 1:3 propensity score-matched subsample from 2016 wave of Health and Retirement Study (HRS), a nationally representative study of older adults. Each lesbian/gay/bisexual (LGB) participant (n=140) was matched with three straight participants (n=420) on age, sex, and education. The average age was 53.8 years (SD=2.3 years), 54% were men, the average education was 14.3 years (SD=2.4 years). Logistic regression results indicated that LGB participants were almost twice as likely to report ever having depression (OR=1.85, 95% CI=1.23-2.80). Conversely, LGB participants were more likely to report having better health (OR=1.47, 95% CI= 1.04-2.07) than straight participants and the two groups did not differ significantly in memory (OR=1.16, 95% CI= 0.82-1.64) from their straight counterparts. In conclusion, it is possible that the stigma due to sexual orientation plays a role in psychological well-being but may also reflect in better physical health but not cognitive health. It is also possible that the better health in LGB participants reflects self-report bias.

scholarly journals SENIOR COMMUNITY CENTER AS A SOCIAL ENGAGEMENT PLATFORM FOR OLDER ADULTS IN NEPAL: AN ADAPTATION OF WESTERN CONCEPT

2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S979-S979
Author(s):  
Sabita Shrestha ◽  
Tina Colson
Keyword(s):  
Social Support ◽  
Older Adults ◽  
Family Support ◽  
Social Engagement ◽  
Support Systems ◽  
Well Being ◽  
Community Centers ◽  
Geriatric Population ◽  
Traditional Family ◽  
Social Support Systems

Abstract Older adults around the world are living longer. Similarly, in Asian countries longevity of older adults have significantly altered the demographics shift as well as the cultural landscape and needs of the society. These changes have compounded with challenges and needs as a community grapples with how to best take care of aging population. Nepal, a developing country, is also faced with a similar demographic shift among the geriatric population. This shift has brought challenges and needs to communities such as health care, daily living needs, social support systems, economic needs, etc. The geriatric population will require social support systems as they age. Historically, older adults have relied on traditional family support systems for their care and needs maintaining cultural values and norms which may burden immediate or extended family members. Recently, traditional family structures along with social support systems are breaking away from their family trees due to community advancement and modernization, and many are leaving for better economic opportunities. This trend has left many older adults alone in social isolation. Despite challenges in the community, Nepal government doesn’t offer infrastructure for social engagement for older adults. One solution to prevent isolation and loneliness is to establish “senior community centers” (western based concept) for social engaging older adults. Based on ecological framework, this presentation proposes a need of “Senior Community Centers” for older adults where they can become involved in social engagements and receive social supports outside traditional family support systems; thus, optimizing their health and well-being.

The glass is not half empty: optimism, pessimism, and health among older adults

2019 ◽  
Vol 32 (1) ◽  
pp. 135-139 ◽  
Author(s):  
Michael D. Barnett ◽  
Ellen A. Anderson
Keyword(s):  
Mental Health ◽  
Older Adults ◽  
Physical Health ◽  
Short Form ◽  
Well Being ◽  
Community Dwelling ◽  
Physical And Mental Health ◽  
Cross Sectional Survey ◽  
Life Orientation Test ◽  
Health And Well Being

ABSTRACTObjectives:Optimism and pessimism are distinct constructs that have demonstrated independent relationships with aspects of health and well-being. The purpose of this study was to investigate whether optimism or pessimism is more closely linked with physical and mental health among older adults.Design:Cross-sectional survey.Participants:Community-dwelling older adults (N = 272) ages 59–95 in the southern United States.Measurements:The Life Orientation Test—Revised and the Short Form 8.Results:At the bivariate level, optimism was associated with higher physical health and mental health, while pessimism was associated with lower physical health and mental health. Multiple-regression analyses as well as comparison of correlation coefficients found that pessimism was more closely associated with physical health and mental health than optimism.Conclusions:These results add to the literature suggesting that, in terms of older adults’ health and well-being, avoiding pessimism may be more important than being optimistic.

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