scholarly journals Epidemiological and Clinical Characteristics of COVID-19: A Retrospective Multi-Center Study in Pakistan

2021 ◽  
Vol 9 ◽  
Author(s):  
Mehmood Ahmad ◽  
Bilal Mahmood Beg ◽  
Arfa Majeed ◽  
Sadaf Areej ◽  
Sualeha Riffat ◽  
...  

The emergence of a pathogen responsible for a mysterious respiratory disease was identified in China and later called a novel coronavirus. This disease was named COVID-19. The present study seeks to determine the epidemiological and clinical characteristics of COVID-19 in Pakistan. This report will exhibit a linkage between epidemiology and clinical aspects which in turn can be helpful to prevent the transmission of the virus in Pakistan. A retrospective, multiple center study was performed by collecting the data from patients' with their demographics, epidemiological status, history of co-morbid conditions, and clinical manifestations of the disease. The data was collected from 31 public-sector and 2 private hospitals across Pakistan by on-field healthcare workers. A Chi-square test was applied to assess the relationship between categorical data entries. A total of 194 medical records were examined. The median age of these patients was found to be 34 years. A total of 53.6% active cases were present including 41.2% males and 12.4% females till the end of the study. Adults accounted for most of the cases (94.3%) of COVID-19. Fever (86.60%), cough (85.05%), fatigue (36.60%), dyspnea (24.74%), and gastrointestinal discomfort (10.31%) were among the most frequently reported signs and symptoms by the patients. However, 4.12% of the total patient population remained asymptomatic. The median duration of hospital stay was found to be 14 (0–19) days. The earliest source of the spread of the virus may be linked to the foreigners traveling to Pakistan. Spread among men was more as compared to women. A few cases were found to be positive, due to the direct contact with pets or livestock. Hypertension (7.73%), diabetes (4.64%), cardiovascular conditions (2.58%) were the most common co-morbidities. The percentage mortality was 2.50% with the highest mortality among elders.

Virulence ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 1557-1568 ◽  
Author(s):  
Jiaxin Chen ◽  
Tao Han ◽  
Mao Huang ◽  
Yi Yang ◽  
Futai Shang ◽  
...  

2021 ◽  
Vol 4 (3) ◽  
pp. 675-688
Author(s):  
Kashif Siddique ◽  
Ra’ana Malik

The aim of the study was to evaluate the level of knowledge of university students about risk factors, signs and symptoms, and impact of diabetes in Punjab, Pakistan. A cross-sectional study design was used for this study. Population of the study was students who were enrolled in public and private universities in Punjab. A multistage sampling method was used for this study. Total 1260 students were selected randomly among which 1087 respondents completed the self-administered questionnaire. Descriptive statistics and the Chi-square test were used through Statistical Package of Social Science (SPSS) version 20.0. The results of the study showed that 544 (50%) respondents were females, most respondents 617 (56.7%) were between 20-23 years old, 589 (54.2%) respondents were studying at undergraduate level, 435 (40%) respondents had poor economic status, 1006 (92.5%) respondents were single, 813 (4.8%) respondents never got their sugar level checked, and 696 (64%) respondents had family history of diabetes. Findings of the study also indicated that most of the respondents 77.9% had inadequate knowledge about risk factors of type 2 diabetes, 73.4% respondents had inadequate knowledge of signs and symptoms of type 2 diabetes, and 72.2% respondents had inadequate knowledge of impact of diabetes. Chi-square test showed that level of knowledge of diabetes was associated with gender (p < .001), education (p < .001), marital status (p < .001), ever checking of sugar (p < .001), and family history of diabetes (p < .001). The study concluded that majority of the respondents had inadequate knowledge of diabetes. Therefore, there is a need of educational programs and awareness sessions for university students. It will be helpful in enhancing students’ knowledge and reducing the prevalence of diabetes in the future of Pakistan.


2012 ◽  
Vol 13 (4) ◽  
pp. 456-459 ◽  
Author(s):  
Bhushan Arun Jawale ◽  
Rahul Redasani ◽  
Lalit Chaudhari ◽  
Narendra Chopde ◽  
Amol Pharande ◽  
...  

ABSTRACT Aim To determine microbial prevalence in the mucous membrane and prosthesis of denture wearers with and without denture stomatitis and to study its relationship with potential clinical cofactors. Materials and methods Saliva was collected from 200 patients (100 female and 100 male) wearing dental prosthesis for measurement of pH. Oral samples of the mucous membrane and of dentures were taken with sterile swab for microbiological analysis. Medical and dietary history of the subjects was recorded. Chi-square test and analysis of varience were used for statistical analysis. Results Diabetes, hypertension and high carbohydrate ingestion was observed in majority of patients. The pH average in saliva was of 5.1. The presence of C. albicans, S. aureus and S. mutans in the mucous membrane was of 55.4, 56.4 and 63.6% respectively. C. albicans was isolated in 69.7% from the prosthesis, whereas S. aureus and S. mutans were isolated in 45.3%. The isolation of C.albicans was more frequent in patients with deture stomatitis. Conclusion C. albicans, S. aureus and S. mutans frequently colonize the oral mucous of denture wearers. This is more frequently observed in patients with denture stomatitis. Clinical significance Denture stomatitis is associated to Candida albicans, different bacteria and other cofactors, such as salivary pH, carbohydrate ingestion, systemic illnesses and medication. How to cite this article Chopde N, Jawale B, Pharande A, Chaudhari L, Hiremath V, Redasani R. Microbial Colonization and their Relation with Potential Cofactors in Patients with Denture Stomatitis. J Contemp Dent Pract 2012;13(4):456-459.


Author(s):  
Brain Guntoro ◽  
Kasih Purwati

Hypertension is one of the number one causes of death and disability in the world. Hypertension contributes nearly 9.4 million deaths from cardiovascular disease each year. Hypertension can cause undesirable effects, it needs good handling, one of them is by doing a hypertension diet. To carry out a hypertension diet requires knowledge, lack of knowledge can increase risk factors for hypertension. This study aims to determine the relationship of the level of knowledge about hypertension diet to the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City. This research method is an analytic observational with a cross-sectional approach conducted at the Baloi Permai Public Health Center Batam City 2018. Sampling technique is a total sampling with a sample of 64 people in 2018 determined by inclusion and exclusion criteria. The results of the study were analyzed with frequency distribution and then tested with the Chi-square test. Based on the results of this study indicate that of the 64 respondents found elderly who have a good level of knowledge are 41 people (64.1%), 48 people (75.0%) have an age range between 60-70 years. 27 people (42.2%) elderly have the last high school education and 40 people (62.5%) have jobs as entrepreneurs. Elderly people who have normal blood pressure are 40 people (62.5%), and those affected by hypertension are 24 people (37.5%). The elderly who have a family history of hypertension is 21 people (32.8%) and those who do not have a history of hypertension are 43 people (67.2%). Chi-Square Test analysis results show the significance value p = 0.009. This number is significant because the p-value is smaller than the significance level (α) ≤ 5% (0.05), so H0 is rejected and Ha is accepted. Therefore it can be concluded that there is a significant relationship about the level of knowledge about the hypertension diet to the incidence of hypertension in the elderly. From the results of this study it was concluded that there was a relationship between the level of knowledge about the hypertension diet and the incidence of hypertension in the elderly at the Baloi Permai Public Health Center Batam City in 2016.


Author(s):  
Dyah Widiastuti ◽  
Dwi Priyanto

Leptospirosis is associated with occupations which exposed workers to contaminated environments. The risk of leptospirosis exposure in the market as a gathering place for many people needs to be assessed, to obtain the basis for decision making to anticipate leptospirosis transmission. This study aimed to determine the relationship between market environmental conditions including market sanitation conditions, the level of rat density and the presence of leptospira-positive rats  toward the history of leptospirosis exposure among market workers (traders and janitors). A cross sectional study conducted in 35 markets in Banjarnegara and 175 market workers randomly selected. Blood samples analysed using ELISA against 40 Kda pathogenic Leptospira protein. Rat trapping  conducted in each market for two days with 100 traps. The caught mice examined with Polymerase Chain Reaction (PCR) to detect the presence of Leptospira bacteria in their kidneys. Leptospirosis exposure was spread in 17 markets in Banjarnegara. The PCR examination showed that the pathogenic Leptospira infected rats were spread in four markets in Banjarnegara. Chi square test showed that the hygene condition in market area was significantly associated with the leptospirosis exposure. Markets workers (traders and janitors) were at risk for leptospirosis proved by high seroprevalence of leptospirosis in this study.


2021 ◽  
Vol 10 (1) ◽  
pp. 72
Author(s):  
Melvanda Gisela Putri ◽  
Roedi Irawan ◽  
Indri Safitri Mukono

ABSTRAKLatar Belakang: Stunting merupakan suatu istilah yang menggambarkan kondisi pertumbuhan tinggi badan kurang berdasarkan umur disesuaikan dengan Z-Score (<-2SD). Stunting pada balita dapat diakibatkan oleh kurangnya asupan zat gizi yang diperlukan bagi pertumbuhan anak. Penelitian dilakukan untuk mengetahui hubungan suplementasi vitamin A, pemberian imunisasi dan riwayat penyakit infeksi yakni diare dan ISPA terhadap kejadian stunting.Tujuan: Mengetahui hubungan suplementasi vitamin A, pemberian imunisasi, dan penyakit infeksi terhadap stunting pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya.Metode: Penelitian ini merupakan penelitian analitik observasional dengan metode cross sectional. Besar sampel adalah 107 anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. terdiri dari 25 anak kelompok stunting dan 82 anak kelompok non- stunting. Cara pengambilan data melalui data sekunder posyandu dan wawancara langsung orang tua anak dengan pengisian kuisioner. Data dianalisis menggunakan uji Chi-Square, Fisher Exact, dan Mann Whitney.Hasil: Penelitian ini menunjukkan hasil terdapat hubungan suplementasi vitamin A dengan stunting (p=0,000), tidak ada hubungan antara pemberian imunisasi terhadap stunting (p=0,332). Dalam riwayat penyakit infeksi, frekuensi diare dan ISPA ditemukan tidak ada hubungan dengan  stunting (p=0,053 dan p=0,082), begitu pula pada lama diare dan lama ISPA tidak berhubungan dengan stunting (p= 0,614 dan p=0,918).Kesimpulan: Suplementasi vitamin A berhubungan signifikan dengan stunting yang diamati pada anak usia 24-59 bulan di Puskesmas Mulyorejo, Surabaya. Kata kunci: kejadian stunting, vitamin A, imunisasi, penyakit infeksi, anak usia 24-59 bulanABSTRACTBackground: Stunting is a term that describes condition of lower height-for-age Z-Score (<-2SD). Stunting among children can be caused by a lack of nutrients needed for children's growth. This study was conducted to determine the relationship between vitamin A supplementation, immunization and a history of infectious diseases, namely diarrhea and ARI to the incidence of stunting.Objectives: To determine the relationship between vitamin A supplementation, immunization, and history of infectious disease with the incidence of stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.Methods: This study was an observational analytic study with cross sectional method. The sample size was 107 children aged 24-59 months at Puskesmas Mulyorejo, Surabaya. This study consisted of 25 children in the stunting group and 82 children in the non-stunting group. The method of data collection was through secondary data from posyandu and direct interviews with parents by filling out questionnaires. Data were analyzed using the chi-square test, fisher exact, and Mann Whitney.Results: The results of this study indicated that there was a relationship between vitamin A supplementation and with stunting (p = 0.000). There was no relationship between immunization and stunting (p = 0.332). In the history of infectious diseases, the frequency of diarrhea and ARI was found to have no relationship with stunting (p = 0.053 and p = 0.082), as well as the duration of diarrhea and duration of ARI there was no association with the stunting (p = 0.614 and p = 0.918).Conclusion: Vitamin A supplementation has significant relationship with stunting in children aged 24-59 months at Puskesmas Mulyorejo, Surabaya.


2020 ◽  
Vol 4 (3) ◽  
pp. 100-111
Author(s):  
Vita Camelia ◽  

Stunting is a children growth problem that occurs a result of chronic malnutrition in the first 1000 days of life. The indicator of stunting is using the height measurement according to age HFA (Height for Age) under -2 SD based on the WHO growth standard curve according to sex. The impacts of stunting are the occurrence of growth disorders, barriers to development and the risk of metabolic disorders in adulthood. One of the risk factors for stunting is history of quality and quantity Antenatal Care (ANC). This study aimed to determine the relationship between quality and quantity history of ANC visits and stunting in toddlers aged 24-59 years in Pujon District Malang Regency. The method used in this research was observational analytic by using cross-sectional design. The population of this study was all mothers who have children aged 24-59 months that were conducted in January 2020. Ninety eight respondents taken by purposive sampling as the sample of the research. The data was obtained by filling out questionnaires and KIA books, then analyzed with chi-square test (α = 0.05). The results showed that there was a significant relationship in quality (p-value = 0.004) and quantity (p-value = 0.003) toward stunting.


Author(s):  
Etienne Belinga ◽  
Isidore Tompeen ◽  
Claude Cyrille Noa Ndoua ◽  
Junie Metogo Ntsama ◽  
Sandrine Mendibi ◽  
...  

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.


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