scholarly journals The Impact of Air Pollution (PM2.5) on Atherogenesis in Modernizing Southern versus Northern China

Atmosphere ◽  
2021 ◽  
Vol 12 (12) ◽  
pp. 1552
Author(s):  
Kamsang Woo ◽  
Changqing Lin ◽  
Yuehui Yin ◽  
Dongshuang Guo ◽  
Ping Chook ◽  
...  
Keyword(s):  
Risk Factors ◽  
Air Pollution ◽  
Northern China ◽  
Age And Gender ◽  
Carotid Imt ◽  
Southern Chinese ◽  
Northern Chinese ◽  
Traditional Risk Factors ◽  
And Gender ◽  
The Impact

To evaluate the impact of PM2.5 air pollution on atherogenic processes in modernizing Southern versus Northern China, we studied 1323 asymptomatic Chinese in Southern and Northern China in 1996–2007. PM2.5 exposure and metabolic syndrome (MS) were noted. Brachial flow-mediated dilation (endothelial function FMD) and carotid intima-media thickness (IMT) were measured by ultrasound. Although age and gender were similar, PM2.5 was higher in Northern China than in Southern China. The Northern Chinese were characterized by lower lipids, folate and vitamin B12, but higher age, blood pressures, MS and homocysteine (HC) (p = 0.0015). Brachial FMD was significantly lower and carotid IMT was significantly greater (0.68±0.13) in Northern Chinese, compared with FMD and IMT (0.57 ± 0.13, p < 0.0001) in Southern Chinese. On multivariate regression, for the overall cohort, carotid IMT was significantly related to PM2.5, independent of location and traditional risk factors (Model R2 = 0.352, F = 27.1, p < 0.0001), while FMD was inversely related to gender, age, and northern location, but not to PM2.5. In Southern Chinese, brachial FMD was inversely correlated to PM2.5, independent of age, whereas carotid IMT was significantly related to PM2.5, independent of age and gender. In Northern Chinese, brachial FMD was inversely related to gender only, but not to PM2.5, while carotid IMT was related to traditional risk factors. Despite a higher PM2.5 pollution in Northern China, PM2.5 pollution was more significantly associated with atherogenic surrogates in Southern compared to Northern Chinese. This has potential implications for atherosclerosis prevention.

Impact of age and sex on subclinical coronary atherosclerosis in a healthy asian population

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Wong ◽  
J Yap ◽  
KK Yeo
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Coronary Artery ◽  
Coronary Atherosclerosis ◽  
Ldl Cholesterol ◽  
Multivariable Analysis ◽  
Asian Population ◽  
Atherosclerotic Cardiovascular Disease ◽  
Age And Gender ◽  
And Gender

Abstract Funding Acknowledgements Type of funding sources: None. Background and Aims The influence of age and gender on clinical atherosclerotic cardiovascular disease is well reported, but literature remains sparse on whether these extend to the disease in its preclinical stage. We aim to report the prevalence, risk-factors and impact of age and gender on the burden of subclinical coronary atherosclerosis in a healthy Asian population. Methods Healthy subjects aged 30-69 years old, with no history of cardiovascular disease or diabetes were recruited from the general population. Subclinical coronary atherosclerosis was quantified via the Coronary Artery Calcium Score (CACS) with CACS of 0 indicating the absence of calcified plaque, 1 to 10 minimal plaque, 11 to 100 mild plaque, and &gt;100 moderate to severe plaque. Results A total of 663 individuals (mean age 49.4 ± 9.2 years, 44.8% male) were included. The prevalence of any CAC was 29.3% with 9% having CAC &gt; 100.  The prevalence was significantly higher in males than females (43.1 vs 18.0%, p &lt; 0.001). These gender differences became increasingly pronounced with increasing age, especially in those with moderate-severe CAC. Multivariable analysis revealed significant associations between increasing age, male, higher blood pressure, increased glucose levels and higher LDL cholesterol levels with the presence of any CAC. LDL cholesterol was more significantly associated with CAC in females compared to males (Pinteraction = 0.022). Conclusions The prevalence of preclinical atherosclerosis increased with age, and was higher in males than females, with gender-specific differences in associated risk factors. These results will better inform individualised future risk management strategies to prevent the development and progression of coronary artery disease within healthy individuals.

scholarly journals A Narrative Review of the Risk Factors for Cancer and the Preventive Opportunities: Current Status, Future Perspectives, and Implications for India

2021 ◽  
Author(s):  
Vinod K. Ramani ◽  
Ganesha D. V. ◽  
Radheshyam Naik
Keyword(s):  
Risk Factors ◽  
Lung Cancer ◽  
Air Pollution ◽  
Cancer Prevention ◽  
Assessment Tools ◽  
Biologically Active ◽  
Pubmed Database ◽  
Risk Of Cancer ◽  
Google Search ◽  
The Impact

Abstract Introduction Clinical cancer can arise from heterogenous pathways through various genetic mutations. Although we cannot predict the timeline by which an individual will develop cancer, certain risk assessment tools can be used among high-risk groups for focusing the preventive activities. As primary level of cancer prevention, healthy lifestyle approach is being promoted. The etiological factors for lung cancer include by-products of industrialization and air pollution. We need to factor the increase in household air pollution as well. Methods “PubMed” database and Google search engines were used for searching the relevant articles. Search terms with Boolean operators used include “Cancer prevention,” “Missed opportunities in cancer causation,” and “incidence of risk factors.” This review includes 20 studies and other relevant literature that address the opportunities for cancer prevention. Body The narrative describes the association between many of the risk factors and development of cancer. This includes tobacco, alcohol, infections, air pollution, physical inactivity, diet, obesity, screening and preventive strategies, chemoprevention, biomarkers of carcinogenesis, and factors that prolong the diagnosis of cancer. Discussion Reports from basic science research provide evidence on the potential of biologically active food components and pharmacological agents for mitigating the risk of cancer and its progression. However, some reports from observational studies and randomized trials have been inconsistent. We need to recognize the impact of sociodemographic factors such as age, sex, ethnicity, culture, and comorbid illness on preventive interventions. Spiral computed tomographic scan is a robust tool for early detection of lung cancer. Conclusion Infectious etiology for specific cancers provides opportunities for prevention and treatment. The complex interplay between man and microbial flora needs to be dissected, for understanding the pathogenesis of relevant malignancies. For reducing the morbidity of cancer, we need to focus on prevention as a priority strategy and intervene early during the carcinogenic process.

scholarly journals Exploring Impact of Age and Gender on Sentiment Analysis Using Machine Learning

Electronics ◽  
2020 ◽  
Vol 9 (2) ◽  
pp. 374 ◽  
Author(s):  
Sudhanshu Kumar ◽  
Monika Gahalawat ◽  
Partha Pratim Roy ◽  
Debi Prosad Dogra ◽  
Byung-Gyu Kim
Keyword(s):  
Machine Learning ◽  
Sentiment Analysis ◽  
Short Term Memory ◽  
Age Groups ◽  
Modern World ◽  
Support Vector ◽  
Digital Information ◽  
Age And Gender ◽  
And Gender ◽  
The Impact

Sentiment analysis is a rapidly growing field of research due to the explosive growth in digital information. In the modern world of artificial intelligence, sentiment analysis is one of the essential tools to extract emotion information from massive data. Sentiment analysis is applied to a variety of user data from customer reviews to social network posts. To the best of our knowledge, there is less work on sentiment analysis based on the categorization of users by demographics. Demographics play an important role in deciding the marketing strategies for different products. In this study, we explore the impact of age and gender in sentiment analysis, as this can help e-commerce retailers to market their products based on specific demographics. The dataset is created by collecting reviews on books from Facebook users by asking them to answer a questionnaire containing questions about their preferences in books, along with their age groups and gender information. Next, the paper analyzes the segmented data for sentiments based on each age group and gender. Finally, sentiment analysis is done using different Machine Learning (ML) approaches including maximum entropy, support vector machine, convolutional neural network, and long short term memory to study the impact of age and gender on user reviews. Experiments have been conducted to identify new insights into the effect of age and gender for sentiment analysis.

scholarly journals Estimation of liver size for liver transplantation: The impact of age and gender

2004 ◽  
Vol 10 (5) ◽  
pp. 678-685 ◽  
Author(s):  
Alexander Choukèr ◽  
André Martignoni ◽  
Martin Dugas ◽  
Wolfgang Eisenmenger ◽  
Rolf Schauer ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Liver Size ◽  
Age And Gender ◽  
And Gender ◽  
The Impact

Bargaining over Remittances in Tajik Extended Families

2021 ◽  
Vol 8 (3) ◽  
pp. 229-250
Author(s):  
Sabiha Yeasmin Rosy ◽  
Fatemeh Nejati
Keyword(s):  
International Migration ◽  
Labor Migration ◽  
Gender Norms ◽  
Transnational Families ◽  
Age And Gender ◽  
Extended Families ◽  
And Gender ◽  
The Impact ◽  
Gender Specific

Abstract This study investigates the impact of male labor migration upon wives living among their husbands’ extended families in Tajikistan. It studies the risks and choices available to such wives in bargaining for remittances, with a particular focus on the risks that daughters-in-law (kelin in Tajik) undertake when negotiating remittances with their mothers-in-law. This paper explores age and gender-specific norms in Tajik transnational families and their minimal opportunities for kelins to bargain and negotiate the risks associated with making “claims” on remittances by using Deniz Kandiyoti’s “patriarchal bargain” and Bina Agarwal’s household bargain framework, as well as extensive fieldwork conducted in Tajikistan. The study concludes that international migration and remittances have had a complex impact on gender norms in Tajikistan, with emerging new forms of passive negotiation by kelins unlikely to undermine patriarchal gender norms in their favor.

‘Genetics load the gun, but the environment pulls the trigger’: novel, emerging and non-traditional risk factors in cardiovascular disease

2021 ◽  
pp. 1-3
Author(s):  
Andrew Richardson
Keyword(s):  
Risk Factors ◽  
Cardiovascular Disease ◽  
Environmental Factors ◽  
Individual Risk ◽  
Traditional Risk Factors ◽  
Individual Risk Factors ◽  
The Impact

In this article, Andy Richardson, BANCC Educational Advisor, examines several important environmental and individual risk factors for cardiovascular disease. Following on from the meeting of Global Leaders at COP26 in Glasgow, he considers the impact of, and exposure to, environmental factors, including pollution and noise.

Evaluation of the Fibromyalgia and Related Risk Factors in Patients with Advanced Kidney Failure Undergoing Hemodialysis

2021 ◽  
Vol 17 ◽  
Author(s):  
Seyed Mostafa Seyedmardani ◽  
Saeed Abkhiz ◽  
Azadeh Megrazi ◽  
Aarefeh Jafarzade ◽  
Golshan Kamali Zonouz
Keyword(s):  
Risk Factors ◽  
Kidney Failure ◽  
Fibromyalgia Syndrome ◽  
Cross Sectional Study ◽  
Hemodialysis Patients ◽  
Cross Sectional ◽  
Age And Gender ◽  
Significant Difference ◽  
Symptom Severity Score ◽  
And Gender

Background : Fibromyalgia syndrome (FMS) is defined as widespread and persistent pain in the musculoskeletal system. There are limited reports regarding the prevalence of fibromyalgia syndrome in patients with advanced kidney failure undergoing regular hemodialysis. Therefore, this study aimed to evaluate the prevalence of fibromyalgia syndrome and its risk factors in a large proportion of patients under the hemodialysis condition. Materials and Methods: In this cross-sectional study, 293 patients who were admitted to the hemodialysis ward were evaluated for fibromyalgia syndrome in an educational hospital. The questionnaire was designed according to symptom severity score (SS score) and widespread pain index (WPI) criteria. The correlation between FMS and various variables, including demographic, clinical, and biochemistry biomarkers, was also precisely calculated by logistic regression. Data were analyzed using SPSS v.17 statistics software. Results: The results showed that, of 293 hemodialysis patients, 130 patients (44.4%) had fibromyalgia, the mean age of patients with and without fibromyalgia was 61.09 ± 15.36 and 53.49 ± 15.38 years old, respectively (P = 0.001). Moreover, there was a significant difference in terms of gender among patients with fibromyalgia syndrome (P = 0.001). To note, there was no significant relationship between the kidney failure etiopathogenesis, duration of dialysis, body mass index (BMI), Kt/v index, history of peritoneal dialysis, and laboratory parameters with fibromyalgia in hemodialysis patients (P > 0.05). However, our findings revealed that both age and gender could be considered as the predictor variables associated with fibromyalgia in patients undergoing hemodialysis. Conclusion: Taken together, in this study, we found that age and gender would be the critical factors in terms of the fibromyalgia syndrome in patients undergoing hemodialysis.

scholarly journals Patients’ general satisfaction with the appearance of anterior maxillary teeth

2017 ◽  
Vol 74 (6) ◽  
pp. 520-525 ◽  
Author(s):  
Vlatka Lajnert ◽  
Daniela Kovacevic-Pavicic ◽  
Hrvoje Pezo ◽  
Aleksandra Stevanovic ◽  
Tatjana Jovic ◽  
...  
Keyword(s):  
Dental Plaque ◽  
Negative Influence ◽  
Cross Sectional ◽  
Age And Gender ◽  
Tooth Shape ◽  
General Satisfaction ◽  
Anterior Teeth ◽  
Dental Appearance ◽  
And Gender ◽  
The Impact

Background/Aim. Dental appearance plays an important role in practically all personal social interactions. The main factors that define the dental appearance are tooth colour, shape and position, quality of restoration, and the general position of the teeth in arch, especially in the anterior region. The aim of this study was to evaluate the impact of dental status (tooth shape, fracture, dental and prosthetic restorations and presence of plaque) on patient''s satisfaction with the dental appearance, controlling for the age and gender. Methods. A total of 700 Caucasian subjects (439 women) aged 18?86 (median 45 years) participated in the cross-sectional study. Study included clinical examination and self-administrated questionnaire based on selfperceived aesthetics and satisfaction with the appearance of their maxillary anterior teeth. Results. A regression analysis demonstrated that presence of dental plaque, tooth fracture, composite fillings and crowns had significant independent contribution and were negative predictors of satisfaction with teeth appearance. Participants with presence of plaque on upper teeth (p < 0.001), fractures (p = 0.005), composite fillings (p < 0.001) and crowns (p = 0.032) were less satisfied than those without it. Model explains 12% or variance of general satisfaction with the appearance of maxillary frontal teeth (p < 0.001) and the major contributors are composite fillings (5.3%) and plaque (3.2%). Tooth shape, age and gender were not significant predictors of satisfaction. Conclusion. Satisfaction with the teeth appearance is under the influence of many factors with significant negative influence of presence of dental plaque, fractures, composite restorations, and crowns.

scholarly journals Mineral Micronutrients in Asthma

Nutrients ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 4001
Author(s):  
Dominika Zajac
Keyword(s):  
Oxidative Stress ◽  
Risk Factors ◽  
Air Pollution ◽  
Defense Mechanisms ◽  
Redox Status ◽  
Chronic Inflammatory Disease ◽  
Modern World ◽  
Medical Issues ◽  
Persistent Inflammation ◽  
The Impact

Asthma represents one of the most common medical issues in the modern world. It is a chronic inflammatory disease characterized by persistent inflammation of the airways and disturbances in redox status, leading to hyperresponsiveness of bronchi and airway obstruction. Apart from classical risk factors such as air pollution, family history, allergies, or obesity, disturbances of the levels of micronutrients lead to impairments in the defense mechanisms of the affected organism against oxidative stress and proinflammatory stimuli. In the present review, the impact of micronutrients on the prevalence, severity, and possible risk factors of asthma is discussed. Although the influence of classical micronutrients such as selenium, copper, or zinc are well known, the effects of those such as iodine or manganese are only rarely mentioned. As a consequence, the aim of this paper is to demonstrate how disturbances in the levels of micronutrients and their supplementation might affect the course of asthma.

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