scholarly journals Amazonian Bacuri (Platonia insignis Mart.) Fruit Waste Valorisation Using Response Surface Methodology

Biomolecules ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1767
Author(s):  
Klenicy K. L. Yamaguchi ◽  
David S. Dias ◽  
Carlos Victor Lamarão ◽  
Karen F. A. Castelo ◽  
Max S. Lima ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Value Chain ◽  
Industrial Waste ◽  
Antioxidant Activities ◽  
Antioxidant Properties ◽  
Value Added ◽  
Extraction Methods ◽  
Experimental Conditions ◽  
Waste Valorisation

Bacuri (Platonia insignis Mart) is a species from the Clusiaceae genus. Its fruit pulp is commonly used in South America in several food products, such as beverages, ice cream and candies. Only the pulp of the fruit is used, and the peels and seeds are considered waste from these industries. As a trioxygenated xanthone source, this species is of high interest for bioproduct development. This work evaluated the mesocarp and epicarp of bacuri fruits through different extraction methods and experimental conditions (pH, temperature and solvent) in order to determine the most effective method for converting this agro-industrial waste in a value-added bioproduct. Open-column procedures and HPLC and NMR experiments were performed to evaluate the chemical composition of the extracts, along with total phenols, total flavonoids and antioxidant activities (sequestration of the DPPH and ABTS radicals). A factorial design and response surface methodology were used. The best extraction conditions of substances with antioxidant properties were maceration at 50 °C with 100% ethanol as solvent for mesocarp extracts, and acidic sonication in 100% ethanol for epicarp extracts, with an excellent phenolic profile and antioxidant capacities. The main compounds isolated were the prenylated benzophenones garcinielliptone FC (epicarp) and 30-epi-cambogin (mesocarp). This is the first study analysing the performance of extraction methods within bacuri agro-industrial waste. Results demonstrated that shells and seeds of bacuri can be used as phenolic-rich bioproducts obtained by a simple extraction method, increasing the value chain of this fruit.

scholarly journals OPTIMIZATION OF EXTRACTION PARAMETERS FOR FUCOXANTHIN, GALLIC ACID AND RUTIN FROM NITZSCHIA THERMALIS

2019 ◽  
Vol 13 (1) ◽  
Author(s):  
Vasfiye Hazal Özyur ◽  
Ayşegül Erdoğan ◽  
Zeliha Zeliha Demirel ◽  
Meltem Conk Dalay ◽  
Semih Ötleş
Keyword(s):  
Response Surface Methodology ◽  
Gallic Acid ◽  
Response Surface ◽  
Desirability Function ◽  
Antioxidant Properties ◽  
Value Added ◽  
Extraction Time ◽  
Solvent Ratio ◽  
Extraction Temperature ◽  
Extraction Parameters

Recently, microalgae have become important in their health, and cosmetic applications since they are viewed as new sources of carotenoids. Fucoxanthin is also a type of carotenoid. The anti-diabetic, anti-obesity, anti-cancer, and antioxidant properties of fucoxanthin have been widely reported. Since these valuable properties, they also represent a valuable resource of nutraceuticals for functional food applications. This study aims to determine the amount of fucoxanthin, gallic acid, and rutin in Nitzschia thermalis obtained from the Ege University Microalgae Culture Collection. The extraction parameters have been optimized using response surface methodology. The extraction temperature (25, 35, and 45°C), the extraction time (10, 20, and 30 min) and the biomass/solvent ratio (0.005, 0.001, and 0.015 g ml-1) have been assessed as response variables in the Box – Behnken design. The amount of fucoxanthin was determined by the C30 column at 450 nm, while both the amount of gallic acid and rutin were separated in the C18 column at 275 nm by HPLC-DAD. In the present study, the optimum extraction conditions providing the maximum amount of fucoxantin, gallic acid, and rutin were selected by applying the “desirability” function approach in response surface methodology. Finally, the temperature has been determined to be 27.30°C, the extraction time 10 minutes, and the biomass ratio 0.05 g ml-1. Under these conditions, the optimum fucoxanthin level has been determined as 5.8702 mg g-1, the gallic acid level as 0.0140 mg g-1, and the rutin level as 0.0496 mg g-1. The findings are in good agreement with international published values for fucoxanthin content. In addition, response surface methodology was shown to be an effective technique for optimising extraction conditions for maximum fucoxanthin yield. In conclusion, these findings may be applied in the development of extraction methodologies for value added microalgea products as well as can serve as a reference for the extraction of fucoxanthin having high gallic acid and rutin from other brown microalgae, and therefore it could potentially be applied in both pharmaceutical and food industries.

Optimization of Aqueous Two Phase Extraction of Proteins from Litopenaeus Vannamei Waste by Response Surface Methodology Coupled Multi-Objective Genetic Algorithm

2019 ◽  
Vol 15 (1) ◽  
Author(s):  
P. Saravana Pandian ◽  
S. Sindhanai Selvan ◽  
A. Subathira ◽  
S. Saravanan
Keyword(s):  
Genetic Algorithm ◽  
Molecular Weight ◽  
Response Surface Methodology ◽  
Response Surface ◽  
Litopenaeus Vannamei ◽  
Value Added ◽  
Phase System ◽  
Two Phase ◽  
Multi Objective ◽  
Multi Objective Genetic Algorithm

Abstract Waste generated from industrial processing of seafood is an enormous source of commercially valuable proteins. One among the underutilized seafood waste is shrimp waste, which primarily consists of head and carapace. Litopenaeus vannamei (L. vannamei) is the widely cultivated shrimp in Asia and contributes to 90 % of aggregate shrimp production in the world. This work was focused on extraction as well as purification of value-added proteins from L. vannamei waste in a single step aqueous two phase system (ATPS). Polyethylene glycol (PEG) and trisodium citrate system were chosen for the ATPS owing to their adequate partitioning and less toxic nature. Response surface methodology (RSM) was implemented for the optimization of independent process variables such as PEG molecular weight (2000 to 6000), pH (6 to 8) and temperature (25 to 45 °C). The results obtained from RSM were further validated using a Multi-objective genetic algorithm (MGA). At the optimized condition of PEG molecular weight 2000, pH 8 and temperature 35 °C, maximum partition coefficient and protein yield were found to be 2.79 and 92.37 %, respectively. Thus, L. vannamei waste was proved to be rich in proteins, which could be processed industrially through cost-effective non-polluting ATPS extraction, and RSM coupled MGA could be a potential tool for such process optimization.

scholarly journals Exploiting Response Surface Methodology (RSM) as a Novel Approach for the Optimization of Phenolic and Antioxidant Activity of Date Palm Fruit

2020 ◽  
Vol 14 (4) ◽  
pp. 572-582
Author(s):  
Soumaya Hachani ◽  
◽  
Sarah Boukhalkhal ◽  
Ziyad Ben Ahmed ◽  
Mohamed Harrat ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Phenolic Compounds ◽  
Response Surface ◽  
Antioxidant Activities ◽  
Palm Fruit ◽  
Ultrasound Extraction ◽  
Solid Ratio ◽  
Methanolic Extracts ◽  
Novel Approach ◽  
Dpph Scavenging

The Box-Behnken design was used to investigate the effect of three independent variables – time, temperature and solvent-to-solid ratio on the responses of total phenolics, total flavonoids, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and cupric ion reducing antioxidant capacity (CUPRAC) of date fruit methanolic extracts. Response surface analysis showed that the optimal ultrasound extraction parameters that maximized the responses were 30 min, 298 K and 74.4 ml/g. Under optimum conditions, UHPLC-DAD-MS/MS was used to tentatively characterize 11 phenolic compounds. The experimental values for the quantification of phenolic compounds and antioxidant activities are in accordance with the predicted values, indicating the suitability of the model and the success of response surface methodology in optimizing the ultrasound extraction conditions.

scholarly journals OPTIMIZATION OF LEVOFLOXACIN REMOVAL FROM AQUEOUS SOLUTION USING ELECTROCOAGULATION PROCESS BY RESPONSE SURFACE METHODOLOGY

2021 ◽  
Vol 52 (1) ◽  
pp. 204-217
Author(s):  
Mohammed & Mohammed-Ridha
Keyword(s):  
Aqueous Solution ◽  
Response Surface Methodology ◽  
Response Surface ◽  
Correlation Coefficient ◽  
Iron Hydroxide ◽  
Second Order ◽  
Experimental Results ◽  
Order Kinetic ◽  
Experimental Conditions ◽  
Good Agreement

This study was aimed to investigate the response surface methodology (RSM) to evaluate the effects of various experimental conditions on the removal of levofloxacin (LVX) from the aqueous solution by means of electrocoagulation (EC) technique with stainless steel electrodes. The EC process was achieved successfully with the efficiency of LVX removal of 90%. The results obtained from the regression analysis, showed that the data of experiential are better fitted to the polynomial model of second-order with the predicted correlation coefficient (pred. R2) of 0.723, adjusted correlation coefficient (Adj. R2) of 0.907 and correlation coefficient values (R2) of 0.952. This shows that the predicted models and experimental values are in good agreement. The results of the kinetic study showed that the second-order kinetic model was in good agreement with the experimental results and suggested that the mechanism of chemisorption controlled the LVX adsorption. The experimental results indicated that the adsorption of LVX on iron hydroxide flocs follows Sips isotherm with the value of the correlation coefficient (R2) of 0.937. Sips isotherm shows that both homogenous and heterogeneous adsorption can occur.

scholarly journals Ultrasound-Assisted Extraction of Total Flavonoids from Corn Silk and Their Antioxidant Activity

2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Ling-Li Zheng ◽  
Guan Wen ◽  
Min-Yong Yuan ◽  
Feng Gao
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Antioxidant Activities ◽  
Total Flavonoids ◽  
Ultrasonic Power ◽  
Ultrasound Assisted Extraction ◽  
Antioxidant Power ◽  
Corn Silk ◽  
Assisted Extraction ◽  
Ultrasound Assisted

Object. Ultrasound-assisted extraction of total flavonoids from corn silk and their antioxidant activities were studied.Methods. Response surface methodology was adopted to optimize the extraction conditions and antioxidant activities of the extracted total flavonoids were detected through ferric reducing antioxidant power (FRAP) assay.Results. Through a three-level, three-variable Box-Behnken design of response surface methodology (RSM) adopting yield as response, the optimal conditions were determined as follows: ultrasonic power 500 W, extraction time 20 min, material solvent ratio 1 : 20, and ethanol concentration 30%. Under the optimum conditions, the extraction yield of total flavonoids was 1.13%. FRAP value of total flavonoids extracted from corn silk was 467.59 μmol/L.Conclusion. The total flavonoids of corn silk could be developed as food natural antioxidant reagents.

scholarly journals Rhizomucor miehei Lipase Supported on Inorganic Solids, as Biocatalyst for the Synthesis of Biofuels: Improving the Experimental Conditions by Response Surface Methodology

Energies ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 831 ◽  
Author(s):  
Juan Calero ◽  
Diego Luna ◽  
Carlos Luna ◽  
Felipa Bautista ◽  
Beatriz Hurtado ◽  
...  
Keyword(s):  
Response Surface Methodology ◽  
Response Surface ◽  
Silica Gel ◽  
Rhizomucor Miehei ◽  
Rhizomucor Miehei Lipase ◽  
Reaction Parameters ◽  
Experimental Conditions ◽  
Inorganic Solids ◽  
Lipozyme Rm Im ◽  
Miehei Lipase

Two inorganic solids have been evaluated as supports of Lipozyme RM IM, a Rhizomucor miehei lipase immobilized on a macroporous anion exchange resin, in order to improve its application as a biocatalyst in the synthesis of biofuels. The experimental conditions have been optimized to get the selective transesterification of sunflower oil, by using a multi-factorial design based on the response surface methodology (RSM). In this way, the effects of several reaction parameters on the selective ethanolysis of triglycerides to produce Ecodiesel, a biodiesel-like biofuel constitute by one mole of monoglyceride (MG) and two moles of fatty acid ethyl ester (FAEE), have been evaluated. Thus, it was obtained that a 6:1 oil/ethanol molar ratio, 0.215 g of biocatalyst supported in silica-gel (0.015 g Lipase/0.2 g silica-gel), 50 µL of 10 N NaOH, together with previous optimized reaction parameters, 35 °C reaction temperature and 120 min of reaction time, gave the best results (conversions around 70%; selectivity around 65%; kinematic viscosities about 9.3 mm2/s) in the reaction studied. Besides, Lipozyme RM IM, supported on silica-gel, biocatalyst exhibited a very good stability, remaining its activity even after 15 cycles.

DRY SLIDING WEAR BEHAVIOR OPTIMIZATION OF STIR CAST LM6/ZrO2 COMPOSITES BY RESPONSE SURFACE METHODOLOGY ANALYSIS

2016 ◽  
Vol 40 (3) ◽  
pp. 351-369 ◽  
Author(s):  
G. Karthikeyan ◽  
G.R. Jinu
Keyword(s):  
Mathematical Model ◽  
Response Surface Methodology ◽  
Response Surface ◽  
Wear Behavior ◽  
Wear Test ◽  
Stir Casting ◽  
Dry Sliding Wear ◽  
Experimental Conditions ◽  
Weight Percentage ◽  
The Mathematical Model

LM6 was reinforced with various percentages of ZrO2 particles by using stir casting method. The prepared samples were subjected to tensile and wear test at variable loads by using a pin-on-disc wear tester. The curve fitting technique was used to develop the respective linear, logarithmic, polynomial, power law equations. The wear worn surface and surface roughness of the specimen were studied. Response Surface Methodology (RSM) was used to minimize the number of experimental conditions and develop the mathematical model between the key process parameters namely weight percentage of ZrO2, load and sliding distance. Analysis of Variance technique was applied to check the validity of the developed model. The mathematical model developed for the specific wear rate was predicted at 99% confidence level and some useful conclusions were made.

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