scholarly journals A Review of THz Technologies for Rapid Sensing and Detection of Viruses including SARS-CoV-2

Biosensors ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 349
Author(s):  
Naznin Akter ◽  
Muhammad Mahmudul Hasan ◽  
Nezih Pala
Keyword(s):  
Human Resources ◽  
Zika Virus ◽  
Viral Particle ◽  
Ebola Virus ◽  
Low Cost ◽  
Virus Detection ◽  
Research Directions ◽  
Non Invasive ◽  
Terahertz Technology ◽  
Virus Zika

Virus epidemics such as Ebola virus, Zika virus, MERS-coronavirus, and others have wreaked havoc on humanity in the last decade. In addition, a coronavirus (SARS-CoV-2) pandemic and its continuously evolving mutants have become so deadly that they have forced the entire technical advancement of healthcare into peril. Traditional ways of detecting these viruses have been successful to some extent, but they are costly, time-consuming, and require specialized human resources. Terahertz-based biosensors have the potential to lead the way for low-cost, non-invasive, and rapid virus detection. This review explores the latest progresses in terahertz technology-based biosensors for the virus, viral particle, and antigen detection, as well as upcoming research directions in the field.

scholarly journals Planning for the unexpected: Ebola virus, Zika virus, what's next?

2016 ◽  
Vol 77 (12) ◽  
pp. 704-707 ◽  
Author(s):  
William Welfare ◽  
Edward Wright
Keyword(s):  
Zika Virus ◽  
Ebola Virus ◽  
Virus Zika

scholarly journals Novel infectious diseases in europe

2017 ◽  
Vol 70 (11-12) ◽  
pp. 385-390
Author(s):  
Dajana Lendak ◽  
Tomislav Preveden ◽  
Nadica Kovacevic ◽  
Slavica Tomic ◽  
Maja Ruzic ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Infectious Diseases ◽  
Zika Virus ◽  
Ebola Virus ◽  
Cost Effective ◽  
Hepatitis E ◽  
West Nile ◽  
Human Contact ◽  
Fast Spreading ◽  
Virus Zika

Introduction. The end of 20th and beginning of 21st century is marked by the discovery of new, supercontagious and fast spreading viral diseases. Since 1967, more than 40 new agents have been identified, including human immunodeficiency virus, Ebola, Marburg fever, severe acute respiratory syndrome, hepatitis C, hepatitis E viruses and Zika virus. Modern lifestyle, availability and speed of air traffic, migrations, as well as climate changes, enable faster spreading of infectious diseases from the regions that were hardly reachable. We selected a few diseases that raised the greatest attention among experts and public in general. Ebola. Ebola virus raises anxiety due to high mortality and fast spreading by using inter-human contact. Zika virus. Zika virus, that most often causes mild symptoms, is potentially responsible for microcephaly in neonates. Dengue. Dengue virus is an ?old story?, but in last decades incidence has multiplied by 30. West Nile virus. Although discovered in 1937, West Nile virus has been found exclusively in rural parts of Africa, while nowadays it represents one of the most important etiological factors of viral meningo-encephalitis all over the world. Hepatitis E. Today it is well-known that hepatitis E virus can cause not only acute viral hepatitis but also potentially blood-transmitted chronic hepatitis in immunocompromised, as well as some neurological disorders. Conclusion. One of the scientific challenges in the future will certainly be the discovery of available and cost-effective diagnostic tests, as well as efficient and safe vaccines for these diseases. Up to now, efficient prophylaxis is available only for Denga virus.

scholarly journals DIFFERENT TECHNIQUES OF EXTRACTION AND ANTIVIRAL ACTIVITIES OF QUERCETIN AGAINST VIRUSES SUCH AS CORONAVIRUS, INFLUENZA VIRUS, EBOLA VIRUS, ZIKA VIRUS, AND OTHER VIRUSES

2020 ◽  
pp. 4-9
Author(s):  
DALILA ABDESSEMED
Keyword(s):  
Influenza Virus ◽  
Antiviral Activity ◽  
Zika Virus ◽  
Ebola Virus ◽  
Bioactive Compound ◽  
Extraction Process ◽  
Favorable Effect ◽  
Barr Virus ◽  
Syncytial Virus ◽  
Virus Zika

Quercetin (QCT) is a flavonoid, existed as a pigment in various plants. It is a bioactive compound that has a favorable effect on human health. Our work concerns the selection of different rapid techniques for QCT extraction, published on the different scientific databases, as ultrasound-assisted enzymatic extraction process, supercritical CO2 extraction, microwave-assisted extraction and consists of researching the antiviral activity of QCT and derivatives against viruses such as coronaviruses, influenza virus, human respiratory syncytial virus, Epstein-Barr virus gastric tumor, anti-hepatitis B virus, Zika virus, and Ebola. Following this research, we found that this molecule has a broad-spectrum antiviral activity. Is it effective in controlling this new form of coronavirus, this devastating virus, which currently affects thousands of people?

scholarly journals Programmable low-cost DNA-based platform for viral RNA detection

2020 ◽  
Vol 6 (39) ◽  
pp. eabc6246 ◽  
Author(s):  
Lifeng Zhou ◽  
Arun Richard Chandrasekaran ◽  
Jibin Abraham Punnoose ◽  
Gaston Bonenfant ◽  
Stephon Charles ◽  
...  
Keyword(s):  
Zika Virus ◽  
Ebola Virus ◽  
Biological Fluids ◽  
Low Cost ◽  
Rna Extraction ◽  
Viral Rna ◽  
Disease Spread ◽  
Rna Detection ◽  
The Cost ◽  
Further Development

Detection of viruses is critical for controlling disease spread. Recent emerging viral threats, including Zika virus, Ebola virus, and SARS-CoV-2 responsible for coronavirus disease 2019 (COVID-19) highlight the cost and difficulty in responding rapidly. To address these challenges, we develop a platform for low-cost and rapid detection of viral RNA with DNA nanoswitches that mechanically reconfigure in response to specific viruses. Using Zika virus as a model system, we show nonenzymatic detection of viral RNA with selective and multiplexed detection between related viruses and viral strains. For clinical-level sensitivity in biological fluids, we paired the assay with sample preparation using either RNA extraction or isothermal preamplification. Our assay requires minimal laboratory infrastructure and is adaptable to other viruses, as demonstrated by quickly developing DNA nanoswitches to detect SARS-CoV-2 RNA in saliva. Further development and field implementation will improve our ability to detect emergent viral threats and ultimately limit their impact.

scholarly journals Glyconanomaterials for Human Virus Detection and Inhibition

Nanomaterials ◽  
2021 ◽  
Vol 11 (7) ◽  
pp. 1684
Author(s):  
Noelia Losada-Garcia ◽  
Carla Garcia-Sanz ◽  
Alicia Andreu ◽  
Trinidad Velasco-Torrijos ◽  
Jose M. Palomo
Keyword(s):  
Influenza Virus ◽  
Ebola Virus ◽  
Antiviral Agents ◽  
Virus Detection ◽  
Improve Patient Care ◽  
Human Virus ◽  
Minimal Invasiveness ◽  
Biological Recognition ◽  
Clinical Drugs ◽  
Virus Zika

Viruses are among the most infectious pathogens, responsible for the highest death toll around the world. Lack of effective clinical drugs for most viral diseases emphasizes the need for speedy and accurate diagnosis at early stages of infection to prevent rapid spread of the pathogens. Glycans are important molecules which are involved in different biological recognition processes, especially in the spread of infection by mediating virus interaction with endothelial cells. Thus, novel strategies based on nanotechnology have been developed for identifying and inhibiting viruses in a fast, selective, and precise way. The nanosized nature of nanomaterials and their exclusive optical, electronic, magnetic, and mechanical features can improve patient care through using sensors with minimal invasiveness and extreme sensitivity. This review provides an overview of the latest advances of functionalized glyconanomaterials, for rapid and selective biosensing detection of molecules as biomarkers or specific glycoproteins and as novel promising antiviral agents for different kinds of serious viruses, such as the Dengue virus, Ebola virus, influenza virus, human immunodeficiency virus (HIV), influenza virus, Zika virus, or coronavirus SARS-CoV-2 (COVID-19).

MICROCEFALIA ACOMETIDA POR INFECÇÃO CONGÊNITA PELO ZIKA VÍRUS

2018 ◽  
Vol 9 (edesp) ◽  
pp. 577-583
Author(s):  
Uverlei Hilario De Jesus ◽  
Gilson Valente Vieira ◽  
Leôncio Torres Costa ◽  
Vera Lúcia Matias Gomes Geron
Keyword(s):  
Zika Virus ◽  
A Priori ◽  
Virus Versus ◽  
Virus Zika

Em 2014 o vírus Zika foi constatado no Brasil e a priori se espalhava apenas com sintomas semelhante a outras doenças virais como a Chikungunya e dengue. No entanto em 2015, ocorreu um grande surto de crianças recém-nascidas com microcefalia, o auto índice de crianças nascida com a má formação levou os especialistas a investigarem as causas. O trabalho realizado tem como objetivo principal apresentar a microcefalia como uma doença hematológica causada pelo Zika vírus. A metodologia utilizada se caracteriza como revisão bibliográfica de caráter exploratório e descritivo, a fim de buscar com precisão dados relevantes sobre o assunto abordado e descrever com pertinência sobre o fenômeno estudado, trazendo informações atualizadas e criteriosas sobre a microcefalia acometida pelo Zika vírus, bem como prevenção para gestantes e cuidados com crianças que nasceram com microcefalia. Os resultados encontrados mostram que o surto de crianças com microcefalia está relacionado com o caso Zika vírus. Os dados mostraram muitos casos prováveis da doença, atualmente, o vírus esta controlado em todo o país, no entanto, a própria ciência prevê mais pesquisas para buscar comprovações concretas da relação Zika vírus versus microcefalia, como também meios de prevenção e tratamentos adequados para mulheres em idade fértil e em período gestacional.

Enhanced electrochemiluminescence of CdS quantum dots capped with mercaptopropionic acid activated by EDC for Zika virus detection

The Analyst ◽  
2021 ◽  
Author(s):  
Hui-Jun Zhang ◽  
Jin Zhu ◽  
Ning Bao ◽  
Shou-Nian Ding
Keyword(s):  
Quantum Dots ◽  
Zika Virus ◽  
Virus Detection ◽  
Cds Quantum Dots ◽  
Mercaptopropionic Acid ◽  
Sandwich Type ◽  
Cds Qds

The mechanism of enhanced ECL of MPA@CdS QDs by EDC activation was investigated, and a sandwich-type ECL immunosensor has been designed for Zika virus detection.

scholarly journals The grades and freshness assessment of eggs based on density detection using machine vision and weighing sensor

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Supakorn Harnsoongnoen ◽  
Nuananong Jaroensuk
Keyword(s):  
Machine Vision ◽  
Vision System ◽  
Low Cost ◽  
Measuring System ◽  
Coefficient Of Determination ◽  
Water Displacement ◽  
Non Invasive ◽  
Future Potential ◽  
Non Destructive ◽  
Egg Freshness

AbstractThe water displacement and flotation are two of the most accurate and rapid methods for grading and assessing freshness of agricultural products based on density determination. However, these techniques are still not suitable for use in agricultural inspections of products such as eggs that absorb water which can be considered intrusive or destructive and can affect the result of measurements. Here we present a novel proposal for a method of non-destructive, non-invasive, low cost, simple and real—time monitoring of the grading and freshness assessment of eggs based on density detection using machine vision and a weighing sensor. This is the first proposal that divides egg freshness into intervals through density measurements. The machine vision system was developed for the measurement of external physical characteristics (length and breadth) of eggs for evaluating their volume. The weighing system was developed for the measurement of the weight of the egg. Egg weight and volume were used to calculate density for grading and egg freshness assessment. The proposed system could measure the weight, volume and density with an accuracy of 99.88%, 98.26% and 99.02%, respectively. The results showed that the weight and freshness of eggs stored at room temperature decreased with storage time. The relationship between density and percentage of freshness was linear for the all sizes of eggs, the coefficient of determination (R2) of 0.9982, 0.9999, 0.9996, 0.9996 and 0.9994 for classified egg size classified 0, 1, 2, 3 and 4, respectively. This study shows that egg freshness can be determined through density without using water to test for water displacement or egg flotation which has future potential as a measuring system important for the poultry industry.

scholarly journals Methods of Respiratory Virus Detection: Advances towards Point-of-Care for Early Intervention

Micromachines ◽  
2021 ◽  
Vol 12 (6) ◽  
pp. 697
Author(s):  
Siming Lu ◽  
Sha Lin ◽  
Hongrui Zhang ◽  
Liguo Liang ◽  
Shien Shen
Keyword(s):  
Viral Load ◽  
Respiratory Virus ◽  
Viral Infections ◽  
Point Of Care ◽  
Human Life ◽  
Low Cost ◽  
Virus Detection ◽  
Frequent Monitoring ◽  
User Friendly ◽  
New Strategies

Respiratory viral infections threaten human life and inflict an enormous healthcare burden worldwide. Frequent monitoring of viral antibodies and viral load can effectively help to control the spread of the virus and make timely interventions. However, current methods for detecting viral load require dedicated personnel and are time-consuming. Additionally, COVID-19 detection is generally relied on an automated PCR analyzer, which is highly instrument-dependent and expensive. As such, emerging technologies in the development of respiratory viral load assays for point-of-care (POC) testing are urgently needed for viral screening. Recent advances in loop-mediated isothermal amplification (LAMP), biosensors, nanotechnology-based paper strips and microfluidics offer new strategies to develop a rapid, low-cost, and user-friendly respiratory viral monitoring platform. In this review, we summarized the traditional methods in respiratory virus detection and present the state-of-art technologies in the monitoring of respiratory virus at POC.

scholarly journals Recent Developments of Antimony-Based Anodes for Sodium- and Potassium-Ion Batteries

2021 ◽  
Author(s):  
Bochao Chen ◽  
Ming Liang ◽  
Qingzhao Wu ◽  
Shan Zhu ◽  
Naiqin Zhao ◽  
...  
Keyword(s):  
Structural Characteristics ◽  
Low Cost ◽  
Potassium Ion ◽  
Research Progress ◽  
Research Directions ◽  
Weak Charge ◽  
Recent Developments ◽  
High Theoretical Capacity ◽  
Further Development ◽  
Sodium And Potassium

AbstractThe development of sodium-ion (SIBs) and potassium-ion batteries (PIBs) has increased rapidly because of the abundant resources and cost-effectiveness of Na and K. Antimony (Sb) plays an important role in SIBs and PIBs because of its high theoretical capacity, proper working voltage, and low cost. However, Sb-based anodes have the drawbacks of large volume changes and weak charge transfer during the charge and discharge processes, thus leading to poor cycling and rapid capacity decay. To address such drawbacks, many strategies and a variety of Sb-based materials have been developed in recent years. This review systematically introduces the recent research progress of a variety of Sb-based anodes for SIBs and PIBs from the perspective of composition selection, preparation technologies, structural characteristics, and energy storage behaviors. Moreover, corresponding examples are presented to illustrate the advantages or disadvantages of these anodes. Finally, we summarize the challenges of the development of Sb-based materials for Na/K-ion batteries and propose potential research directions for their further development.

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