scholarly journals Mixed Depression: A Mini-Review to Guide Clinical Practice and Future Research Developments

2022 ◽  
Vol 12 (1) ◽  
pp. 92
Author(s):  
Antimo Natale ◽  
Ludovico Mineo ◽  
Laura Fusar-Poli ◽  
Andrea Aguglia ◽  
Alessandro Rodolico ◽  
...  

The debate on mixed states (MS) has been intense for decades. However, several points remain controversial from a nosographic, diagnostic, and therapeutic point of view. The different perspectives that have emerged over the years have turned into a large, but heterogeneous, literature body. The present review aims to summarize the evidence on MS, with a particular focus on mixed depression (MxD), in order to provide a guide for clinicians and encourage the development of future research on the topic. First, we review the history of MS, focusing on their different interpretations and categorizations over the centuries. In this section, we also report alternative models to traditional nosography. Second, we describe the main clinical features of MxD and list the most reliable assessment tools. Finally, we summarize the recommendations provided by the main international guidelines for the treatment of MxD. Our review highlights that the different conceptualizations of MS and MxD, the variability of clinical pictures, and the heterogeneous response to pharmacological treatment make MxD a real challenge for clinicians. Further studies are needed to better characterize the phenotypes of patients with MxD to help clinicians in the management of this delicate condition.

Author(s):  
Suresh Mani ◽  
Shobha Sharma ◽  
Devinder Kaur Ajit Singh

Objective : The aim of this study was to examine the use of WPD software to evaluate FHP using digital photogrammetry method.Method: A total of 15 adults with no history of neck pain for the past 6 months were recruited for the study. Using digital photogrammetry and sagittal head tilt, craniocervical and shoulder angles (SAs) were measured using a WPD, which is an open resource of web or Windows-based software.Result: Fifteen participants aged 17–40 years (mean 24.7±6.3 years) were examined. Sagittal head tilt and craniocervical angles were 16.35°±8.33° and 47.43°±7.97°, respectively. SA was 52.28°±12.46°.Conclusion: WPD may be used to evaluate FHP in the clinical settings. However, future research is required to determine the validity and reliability of WPD among patients with neck-related musculoskeletal disorders with a larger sample.


Author(s):  
Katrin Wodzicki ◽  
Johannes Moskaliuk ◽  
Ulrike Cress

In this chapter, the application of patterns in the context of social practice will be considered from a psychological point of view. After briefly introducing the history of patterns, this chapter will discuss the specific conditions that apply for formulating and using patterns of social practice, as well as the benefits and challenges of their application. This discussion will result in four main challenges. In order to address them, the chapter presents psychological approaches that deal with the relevant issues and help to understand potential benefits of patterns of social practice. It concludes with some remaining open questions for future research. The entire chapter focuses on the structure that patterns provide, and how this structure supports the communication, exchange, and learning of social practice. The discussion of pattern writing processes (e.g., the process of shepherding) would need a motivational and practical consideration rather than a cognitive psychological one.


2017 ◽  
Vol 21 (3) ◽  
pp. 267-286 ◽  
Author(s):  
Jörg H. Mühlhans

Over the last several decades low frequency and infrasound have become relevant to many fields of research – most recently psychology and musicology, among others. Interpretation of data from experimental research has raised concern that low frequency and infrasound could be potentially harmful to humans’ well-being. While the physiological and psychological effects of infrasound are well documented, a variety of myths promulgated by pseudoscientific authors and newspapers still make it difficult to distinguish between fact and fiction, especially for people with little or no knowledge in acoustics. Myths are widespread today and result mainly from the one-dimensional view on sound, out-of-context citations, and a number of “sensational” findings from biased studies. The aim of this review is to evaluate the relevance of data from a music-psychological and psychoacoustic point of view, to give a consistent overview of the history of research, to examine the transferability of findings, and to trace the origins of myths to debunk them. Additionally, general information about the characteristics of low frequency sound, its production, measurement, and difficulties in experimental research is given to avoid mistakes in future research.


Author(s):  
Kelly C. Allison ◽  
David B. Sarwer

Body image disturbances are common among women in the general population. Less is known about their prevalence and impact during pregnancy. This chapter examines the history of body image theory and research. Next, we examine issues related to body image during pregnancy, such as pregravid weight, gestational weight gain, and the unique ways women think about the changes to their body during pregnancy. The role of physical activity, mood, and eating disorders in relation to peripartum body image disturbance is also discussed. Finally, assessment of body image disturbance and existing treatments are presented. Future research is needed to develop peripartum-specific body image assessment tools and to assess the impact of psychosocial interventions during and after pregnancy on body image dissatisfaction.


2008 ◽  
Vol 36 (1) ◽  
pp. 185-244
Author(s):  
Vyacheslav V. Ivanov

Semiotic and linguistic studies of the 20th century have been important mostly in two senses — (1) they have opened a road for comparative research on the origin and development of language and other systems of signs adding a new dimension to the history of culture; (2) they have shown a possibility of uniting different fields of humanities around semiotics suggesting a way to trespass separation and atomisation of different trends in investigating culture. In the 21st century one may hope for closer integration of semiotics and exact and natural sciences. The points of intersection with the mathematical logic, computer science and information theory that already exist might lead to restructuring theoretical semiotics making it a coherent and methodologically rigid discipline. At the same time, the continuation of neurosemiotic studies promises a breakthrough in understanding those parts of the work of the brain that are most intimately connected to culture. From this point of view semiotics may play an outstanding role in the synthesis of biological science and humanities. In my mind that makes it a particularly important field of future research.


Author(s):  
Ivan Boserup ◽  
Karsten Christensen

Ivan Boserup & Karsten Christensen: Anders Sørensen Vedel’s manuscript about Marshal Stig. Two comments on Svend Clausen’s thesis in Fund og Forskning 55, 2016 Svend Clausen has in vol. 55 of Fund og Forskning called attention to a lost and “forgotten” parchment manuscript described by Anders Sørensen Vedel in 1595 as “The History of Marshal Stig” containing key documents related to the trial which followed the assassination in Finderup Grange of King Eric V ‘Glipping’ of Denmark (1259–1286). Clausen’s evidence consists of registrations of manuscripts known only through their titles, which had been available to the Danish historians Anders Sørensen Vedel (1542–1616), Niels Krag (1550–1602), and Jon Jakobsen ‘Venusinus’ (1563–1608), but appear ultimately to have burned in the fire of Copenhagen in 1728. The sources referred to by Clausen were published in one case by H. F. Rørdam in 1874, in all other cases in the appendix to S. Birket Smith’s History of the University Library of Copenhagen, 1882, reprinted 1982. Apparently inspired by a casual remark made in 1891 by the then very young historian Mouritz Mackeprang, Svend Clausen argues that despite the lack of extant copies and quotations etc., the manuscript’s supposedly exclusively judicial contents and allegedly very considerable volume reveal the “existence” of such an important source that future research on the background and consequences of the royal assassination must take much more account of this lost source than has been the case until now. Reviewing Svend Clausen’s arguments, Ivan Boserup corrects Rørdam’s and Clausen’s incomplete reading of the source on which the latter builds his identification of Vedel’s manuscript with descriptions of a lost manuscript “Concerning King Eric [Glipping],” and rejects Clausen’s interpretation of “… cum adversariis ac diversis” (Clausen seems unaware of the literary concept of adversaria), on which all his further arguments are based. From his professional standpoint as a historian, Karsten Christensen refers to Vedel’s strong focus on Marshal Stig in his collection of One Hundred Danish Folk Songs (publ. 1591), to Vedel’s idiosyncratic manner of describing his manuscripts from the point of view of his own main interests, and to the fact that in contrast to the Jens Grand trial held before the Pope in Rome in 1296, one should not expect written actiones to have been delivered at the meeting of the Danish grandees in Nyborg Castle in 1286 subsequent to the murder of Eric Glipping. Christensen therefore suggests that it is much more probable that the manuscript referred to in Vedel’s registration refers to a lost manuscript that, contrary to the one associated by Svend Clausen with Vedel’s lost manuscript, can be followed closely all the way up to 1728, and the contents of which have been detailed by the historian Stephanus Stephanius (1599–1650).


2019 ◽  
Vol 35 (S1) ◽  
pp. 60-60
Author(s):  
Yolanda Triñanes Pego ◽  
Lucía Varela ◽  
José Mazaira-Castro ◽  
Maria José Faraldo Vallés

IntroductionIn the past decades the community-based participatory research method known as PhotoVoice has gained relevance, but there are few published studies on its application in the field of health technology assessment (HTA) and clinical practice guidelines (CPGs). The aim of this presentation was to describe a PhotoVoice project linked to a CPG on major depression in children and adolescents.MethodsThe design of the study was adapted to the main objective, which was to enhance the understanding of major depression and improve clinical practice with the contributions of clinicians, methodologists, and patients. Seven adolescents and ten of their family members participated in the study through PhotoVoice sessions and focus groups. The audio recordings of all sessions were transcribed verbatim and coded, and a thematic analysis was undertaken.ResultsSix themes emerged: (i) a lack of understanding and information about depression in childhood and adolescence; (ii) the importance of support groups; (iii) the need to favor early care and access to services; (iv) the adaptation of therapeutic strategies tailored to individual needs; (v) the sensitivity of professionals; and (vi) fostering interaction between the health and education systems. Photographic exhibitions were planned to share the main results. These exhibitions were promoted to increase public awareness and reduce stigmatization, and to reach clinicians and policy makers. From a methodological point of view, the use of PhotoVoice in this study helped to effectively incorporate the lived experiences, concerns, and preferences of patients and their relatives into the CPG. The study also confirmed the value of photographs and participatory methods. The main limitations and strengths of the study, as well as suggestions for future research, are also outlined.ConclusionsPhotoVoice is a flexible, effective, and innovative method of obtaining information about patients’ perspectives and experiences, and it offers the added value of being able to reach the main stakeholders, including policymakers and the public.


2020 ◽  
Vol 22 (4) ◽  
pp. 192-195
Author(s):  
I. I. Zhirkov ◽  
A. V. Gordienko ◽  
I. M. Pavlovich ◽  
V. V. Yakovlev ◽  
D. Yu. Serdyukov

The presents modern information about a non-invasive instrumental technique for assessing fibrotic changes in the liver elastography. The data on the history of the origin of the term elastography are presented, several of its definitions are given, and attention is also paid to the main principle of the technique percussion, which is traditionally used in an objective study of a patient. The facts about the dual terminology of the technique in the literature are presented, in which some authors use the term elastography, and the other part elastometry. When analyzing the literature, it turned out that in foreign sources the term elastography is much more often used, and both names of the method are used in Russian. Given the greater prevalence of the elastography option, it is more logical to use it, but each of these names has its own right to exist. Definitions are given for the basic physical concepts associated with the elastography method elasticity, rigidity and Youngs modulus of elasticity. From the point of view of application in clinical practice, elastography techniques can be divided into four groups: compression elastography, which is more often used in oncodiagnostics, transient, point and two-dimensional shear wave elastography, used in the diagnosis of liver fibrosis. Physical classification involves dividing elastography into two types: static, which includes compression elastography, and dynamic, which includes transient, point and two-dimensional shear wave elastography. Transient elastography is implemented in devices of the FibroScan family, point elastography in ultrasound scanners from Hitachi Aloka, Siemens and Philips, two-dimensional shear wave elastography in devices from Supersonic Imagine, Toshiba, Siemens, Mindray, General Electric. The widest range of possibilities for assessing liver fibrosis is provided by two-dimensional shear wave elastography. The combined use of several techniques is expected to increase the diagnostic accuracy in determining fibrosis. Magnetic resonance elastography has the greatest accuracy among elastographic techniques, but its application is limited due to the complexity and high cost of equipment, therefore, this technique has not yet found wide application in clinical practice.


CNS Spectrums ◽  
2017 ◽  
Vol 22 (2) ◽  
pp. 186-195 ◽  
Author(s):  
Alessandro Cuomo ◽  
Viktoriya L. Nikolova ◽  
Nefize Yalin ◽  
Danilo Arnone ◽  
Andrea Fagiolini ◽  
...  

Mixed states in bipolar disorder have been neglected, and the data concerning treatment of these conditions have been relatively obscure. To address this, we systematically reviewed published pharmacological treatment data for “mixed states/episodes” in mood disorders, including “with mixed features” in DSM–5. We searched PubMed, MEDLINE, The Cochrane Library, clinicaltrials.gov, and controlled-trials.com (with different combinations of the following keywords: “mixed states/features,” “bipolar,” “depressive symptoms/bipolar depression,” “manic symptoms,” “treatment,” “DSM–5”) through to October 2016. We applied a quality-of-evidence approach: first-degree evidence=randomized placebo-controlled studies of pharmacological interventions used as monotherapy; second-degree evidence=a similar design in the absence of a placebo or of a combination therapy as a comparative group; third-degree evidence=case reports, case series, and reviews of published studies. We found very few primary double-blind, placebo-controlled studies on the treatment of mixed states: the preponderance of available data derives from subgroup analysis performed on studies that originally involved manic patients. Future research should study the effects of treatments in mixed states defined using current criteria.


2021 ◽  
Vol 11 (10) ◽  
pp. 572
Author(s):  
Jaana Seikkula-Leino ◽  
Maria Salomaa

This research contributes to the growing discussion on entrepreneurial competencies from a multidisciplinary point of view, integrating elements of entrepreneurship research, education sciences, and psychology. Despite many efforts to develop and utilize different entrepreneurial constructs in entrepreneurship education, there is still a lack of theoretical framework for systematic development and measurement validation related to entrepreneurial competencies. This paper aims to widen the theoretical and conceptual discussion on entrepreneurial competencies by stressing the roles of self-esteem and self-efficacy. The study aims to contribute to the academic discussion (1) by addressing this research gap through a literature-based analysis on how entrepreneurial competencies, self-efficacy and self-esteem relate to each other; and (2) by presenting a conceptual framework (ENTself) for further development of entrepreneurship education. The results of the study reflect how self-esteem and self-efficacy are connected, and how they can be aligned with entrepreneurial competencies. We argue that a systematic, theory-based approach to further research on entrepreneurial competencies, based on the proposed framework, is needed for a broader understanding and facilitation of entrepreneurship education. Also, the development of assessment tools adapted from ENTself is suggested for conducting future research of the framework and its validation.


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