scholarly journals Carbon Nanodots Synthesized from Dunaliella salina as Sun Protection Filters

2020 ◽  
Vol 6 (4) ◽  
pp. 69
Author(s):  
Theodoros G. Chatzimitakos ◽  
Athanasia Kasouni ◽  
Anastassios Troganis ◽  
Ioannis Leonardos ◽  
Ioannis Tzovenis ◽  
...  
Keyword(s):  
Wound Healing ◽  
Citric Acid ◽  
Dunaliella Salina ◽  
Sun Protection ◽  
Uv Protection ◽  
Carbon Nanodots ◽  
The Sun ◽  
In Vitro Experiments ◽  
Insight Into

Carbon nanodots (CNDs) are more and more being exploited for various applications including biological ones. To this end, they have been thoroughly studied for their potential as antibacterial, wound healing, and bioimaging agents. In this study, we examined the sun protection properties of CNDs. Dunaliella salina was selected as a promising precursor for the synthesis of CNDs which were compared with those produced by citric acid, a widely used precursor for such materials. The CNDs were examined spectrophotometrically, and the sun protection factors were calculated. Additionally, in vitro experiments were carried out to evaluate their UV protection properties and to obtain better insight into whether CNDs are suitable to be used as filters for the development of new sunscreens. The results were conclusive that both CNDs possess favorable properties that potentiate their use for the development of sunscreens. However, the CNDs from Dunaliella salina were found to be superior to those derived from citric acid. Therefore, they can further be exploited as sun protection filters.

scholarly journals Development of Bioinspired Gelatin and Gelatin/Chitosan Bilayer Hydrofilms for Wound Healing

Pharmaceutics ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 314 ◽  
Author(s):  
Itxaso Garcia-Orue ◽  
Edorta Santos-Vizcaino ◽  
Alaitz Etxabide ◽  
Jone Uranga ◽  
Ardeshir Bayat ◽  
...  
Keyword(s):  
Wound Healing ◽  
Citric Acid ◽  
Wound Dressing ◽  
Ex Vivo ◽  
Lower Layer ◽  
Transmission Rate ◽  
Dry Weight ◽  
Porous Matrix ◽  
In Vitro Cytotoxicity

In the current study, we developed a novel gelatin-based bilayer wound dressing. We used different crosslinking agents to confer unique properties to each layer, obtaining a bioinspired multifunctional hydrofilm suitable for wound healing. First, we produced a resistant and non-degradable upper layer by lactose-mediated crosslinking of gelatin, which provided mechanical support and protection to overall design. For the lower layer, we crosslinked gelatin with citric acid, resulting in a porous matrix with a great swelling ability. In addition, we incorporated chitosan into the lower layer to harness its wound healing ability. FTIR and SEM analyses showed that lactose addition changed the secondary structure of gelatin, leading to a more compact and smoother structure than that obtained with citric acid. The hydrofilm was able to swell 384.2 ± 57.2% of its dry weight while maintaining mechanical integrity. Besides, its water vapour transmission rate was in the range of commercial dressings (1381.5 ± 108.6 g/m2·day). In vitro, cytotoxicity assays revealed excellent biocompatibility. Finally, the hydrofilm was analysed through an ex vivo wound healing assay in human skin. It achieved similar results to the control in terms of biocompatibility and wound healing, showing suitable characteristics to be used as a wound dressing.

An Analysis of the Postgastrula Differentiation of the Hypomere

Development ◽  
1961 ◽  
Vol 9 (2) ◽  
pp. 294-309
Author(s):  
Cyril V. Finnegan
Keyword(s):  
Early Age ◽  
In Vitro Experiments ◽  
Experimental Conditions ◽  
Tissue Mass ◽  
Intimate Association ◽  
Insight Into

Since the publication of earlier papers (Finnegan, 1953, 1955) the investigation of the capacity of the salamander hypomeric mesoderm for histogenesis under a variety of experimental conditions has continued. It is perhaps prudent at this time to initiate a series of reports with results obtained from in vitro experiments which were designed to gain some insight into the roles of competence, tissue mass, and endodermal influence relative to hypomeric differentiation in Ambystoma. This portion of the mesoderm is destined to undergo its differentiation far removed from the dorsal axial influences of the chorda-mesoderm but with its inner (splanchnic) material in rather intimate association with the endoderm, a tissue known to be determined at an early age and metabolically active, two conditions which lead one to suspect it of inductor potentialities (Nieuwkoop, 1947; Copenhaver, 1955).

scholarly journals Aktifitas Tabir Surya Dengan Nilai Sun Protection Factor (SPF) Sediaan Losion Kombinasi Ekstrak Kayu Manis Dan Ekstrak Kulit Delima Pada Paparan Sinar Matahari Dan Ruang Tertutup

2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Youstiana Dwi Rusita ◽  
Indarto A.S
Keyword(s):  
Statistical Tests ◽  
Punica Granatum ◽  
Sun Protection ◽  
Premature Aging ◽  
The Sun ◽  
Closed Space ◽  
Protection Factor ◽  
Pomegranate Peel ◽  
Sun Protection Factor

Abstract : SPF, Kayumanis, Pomegranate, Lotions. The Sun produces ultraviolet radiation that causes damage to the skin texture, premature aging, burning skinreactions and skin cancer in exposed skin in a long period. One of the ways to protect skin from UV radiation use sunscreen lotions. Stem bark of cinnamon (Cinnamomun burmani) and pomegranate peel (Punica granatum) is known as an antioxidant activity and have a compound that is potentially as sunscreens. This research aims to know the activity of sunscreen with an SPF value of sunscreen lotions of pomegranate peel and cinnamon extract and the warming rays of the Sun and closed space. The determination of the value of the sun protection factor is done with methods of in vitro in Mansur using spectrophotometer UV-Vis. SPF Value calculated based on the Absorbance at a wavelength of 290-320 nm. The result is a non parametric Test is analyzed using MannWhitney test. Results of organoleptic the colored is yellow brown, like to emultion and shaped the distinctive, smell of cinnamon, less homogeneous, showed the value of pH5.63, dispersive power 6 cm, adhesion 1.75 seconds and viscosity 5,500 cps. Preparations that are exposed in the Sunlight showed the value of SPF 20.146 hereaspreparations stored in enclosed space showed the value of SPF 26.398. The results of statistical tests indicate that there is no difference between the SPF on reparations that are exposed to sunlight and in a closed space with alpha value > 0.05.

scholarly journals A Randomized Study to Determine the Sun Protection Factor of Natural Pterostilbene from Pterocarpus Marsupium

Cosmetics ◽  
2020 ◽  
Vol 7 (1) ◽  
pp. 16 ◽  
Author(s):  
Muhammed Majeed ◽  
Shaheen Majeed ◽  
Renuka Jain ◽  
Lakshmi Mundkur ◽  
H. R. Rajalakshmi ◽  
...  
Keyword(s):  
Skin Irritation ◽  
Radical Scavenging ◽  
Sun Protection ◽  
The Sun ◽  
Protection Factor ◽  
Pterocarpus Marsupium ◽  
Sun Protection Factor ◽  
Harmful Effects

Ultraviolet (UV) rays and its harmful effects have always been a concern to skin health. Sunscreen and sunblock prevent the harmful effects of UV radiation on the skin. Sun Protection Factor (SPF) is an indication of the sun-protective capacity of an ingredient. There is an ever increasing interest in the cosmetic industry for developing novel functional ingredients from natural sources. The purpose of this study was to determine in-vitro and in vivo SPF of natural 90% pterostilbene extracted from the dried heartwood of Pterocarpus marsupium (Indian Kino). The SPF of purified pterostilbene and a formulation containing 0.4% pterostilbene was determined In Vitro using a UV spectrophotometer. Pterostilbene had an SPF of 21.73 ± 0.06, while the cream formulation had an SPF of 8.84 ± 0.01. The in vivo SPF of the 0.4% pterostilbene cream in humans was found to be 6.2 ± 1.30. Primary skin irritation tests in human subjects showed the formulation was safe and had no irritation potential. Pterostilbene was also found to have significant antioxidant activity as determined by free radical scavenging assays in vitro. These results suggest that natural pterostilbene is an antioxidant and shows SPF value both in-vitro and in the human clinical study and thus could be used as an ingredient in topical sun-protective formulations.

POTENSI TONGKOL JAGUNG (Zea Mays L.) SEBAGAI SUNSCREEN DALAM SEDIAAN HAND BODY LOTION

2017 ◽  
Vol 2 (2) ◽  
pp. 198
Author(s):  
Dewi Ekowati ◽  
Inaratul Rhizky Hanifah
Keyword(s):  
Sun Protection ◽  
Skin Aging ◽  
The Sun ◽  
Skin Damage ◽  
Corn Cob ◽  
Protection Factor ◽  
Physical Quality ◽  
Sun Protection Factor ◽  
Dispersive Power

The over exposure sunlightis on the skin provides of damage. Skin damage caused the over exposure sunlightis can occur in the short term such as erythema or long term such as premature skin aging and even skin cancer. One way that can be done to minimize the amount of UV that penetrated into the skin is to use sunscreen. Corn cob contain the chemical compounds of phenolic, which suspected to have the protection activity toward the UV B rays. The study aims to make preparations hand body lotion that meet good physical quality of the corn cob extract  as a sunscreen. Hand made three body lotion formula with extract concentrations of corn cob 10% FI, FII FIII 15% and 20%. Testing the physical properties of the test hand body lotion include viscosity, dispersive power and pH. The effectiveness of a sunscreen is based on a determination of the value of the Sun Protection Factor (SPF) in vitro. The third formula has a good physical quality lotion that viscosity 50-1000 dPas, the scatter 5-7 cm, pH 4.5 -7. The effectiveness of sunscreen based on the value of the Sun Protection Factor (SPF), the effectiveness FIII in the category of extra protection is 7.23. SPF value FI  FII 5.13 and 5.67 so that FI and FII into the category of moderate protection

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