scholarly journals Preliminary Investigation on Degradation Behavior and Cytocompatibility of Ca-P-Sr Coated Pure Zinc

Coatings ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 43
Author(s):  
Mingfeng Ke ◽  
Danhua Xie ◽  
Qiangqiang Tang ◽  
Shenghui Su

Zinc and its alloys show a good application prospect as a new biodegradable material. However, one of the drawbacks is that Zn and its alloys would induce the release of more Zn ions, which are reported to be cytotoxic to cells. In this study, a Ca-P-Sr bioactive coating was prepared on the surface of pure zinc by the hydrothermal method to address this issue. The morphology, thickness, and composition were characterized, and the effects of the coating on the degradation, cell viability, and ALP staining were investigated. The results demonstrated that the degradation rate of pure zinc was reduced, while the cytocompatibility was significantly improved after pure zinc was treated with Ca-P-Sr coating. It is considered that the Ca-P-Sr bioactive coating prepared by the hydrothermal method has promising application in the clinic.

Author(s):  
Amirhossein Bakhtiiari ◽  
Rezvan Khorshidi ◽  
Fatemeh Yazdian ◽  
Hamid Rashedi ◽  
Meisam Omidi

In recent decades, three dimensional (3D) bio-printing technology has found widespread use in tissue engineering applications. The aim of this study is to scrutinize different parameters of the bioprinter – with the help of simulation software – to print a hydrogel so much so that avoid high amounts of shear stress which is detrimental for cell viability and cell proliferation. Rheology analysis was done on several hydrogels composed of different percentages of components: alginate, collagen, and gelatin. The results have led to the combination of percentages collagen:alginate:gelatin (1:4:8)% as the best condition which makes sol-gel transition at room temperature possible. The results have shown the highest diffusion rate and cell viability for the cross-linked sample with 1.5% CaCl2 for the duration of 1 h. Finally, we have succeeded in printing the hydrogel that is mechanically strong with suitable degradation rate and cell viability.


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Haiwang Wang ◽  
Guanqi Wang ◽  
Yukai Zhang ◽  
Yuan Ma ◽  
Zhengjie Wu ◽  
...  

Abstract To increase the utilization ratio and catalytic efficiency of the nano TiO2, The RGO/TiO2/(Ag) powders and RGO/TiO2/Ag aerogel photocatalyst were designed and prepared. The composition and microstructure of RGO/TiO2/(Ag) powders and RGO/TiO2/Ag aerogel were studied, in addition, the photocatalytic activity of RGO/TiO2/(Ag) powders and RGO/TiO2/Ag aerogel was researched by the photocatalytic degradation behavior of formaldehyde solution and formaldehyde gas respectively. The result indicate that TiO2 is uniformly loaded on the surface of RGO with a particle size of 10 nm to 20 nm. When the amount of graphene oxide added is 1 wt%, RGO/TiO2 powder has the highest degradation effect on formaldehyde solution, in addition, the introduction of Ag can greatly improve the photocatalytic effect of the sample. The results also show that the pore size of RGO/TiO2/Ag aerogel is between 7.6 nm and 12.1 nm, and the degradation rate of formaldehyde gas is 77.08% within 2 hours.


2012 ◽  
Vol 06 ◽  
pp. 774-779
Author(s):  
QIAN ZHANG ◽  
X. G. Wang ◽  
PENG CAO ◽  
WEI GAO

Biodegradable stenting and implantation materials have received considerable attention in biomaterials community, with magnesium having been received most wide attention. However, magnesium corrodes too fast by nature, in human body environment. A new type of biodegradable metal – Fe and its alloys – has been introduced in recent years. In this study, a Fe 35 wt % Mn alloy was produced using powder sintering. Powder mixture was mechanically milled, pressed and then sintered to consolidate powder compacts. Microstructure characterization and hardness measurement were carried out on the as-sintered samples. In vitro degradability evaluation of the samples was performed in 5% NaCl and Simulated Body Fluid (SBF) media. The experimental results show that a higher porosity results in a higher degradation rate. All samples, with porosity being from 6.5% to 12.2 %, revealed a degradation rate from 0.6 to 1.4 mm/year.


2013 ◽  
Vol 743-744 ◽  
pp. 843-848
Author(s):  
Ya Ping Zhang ◽  
Qian Qian Zhi ◽  
Lian Qing Yu ◽  
Kai Tuo Dong ◽  
Ri Shan Liu ◽  
...  

In order to improve the separation efficiency and the circular utilization ratio of the catalyst, the Fe-doped nanotitanium and nanotitanium supported on Fe2O3 carrier was prepared by hydrothermal method. The tetra-butyl titanate and ethanol were used as starting materials to prepare nanotitanium. The results of Fe-doped nanotitanium showed that the doping of iron changed the nanotitanium crystal and crystal morphology. No matter UV-light or mercury lamp 577 nm irradiation, the samples with 0.5 mM Fe addition showed the highest photo catalytic activity, with degradation rate of methyl blue above 95%. The structure, photo catalytic activity and magnetic properties analysis showed that the magnetic nanotitanium met the purpose of separation between the catalyst and reaction solution. The photo catalytic activity of nanotitanium supported on Fe2O3 carrier has respond to visible light. With mercury lamp 577 nm as irradiation source, degradation rate of methylene blue light could reach 63.40%.


2021 ◽  
Vol 309 ◽  
pp. 01085
Author(s):  
Sandeep Kumar Jhamb ◽  
Ashish Goyal ◽  
Anand Pandey ◽  
Jay Marwaha ◽  
Jay Matai

In the last six decades, it has been made a great advancement in the field of engineering material especially in biomaterials, including metal alloys, composites, polymers, ceramics, and metallic glasses. Different form of these biomaterial are used as a engrafts. Unlike conventional materials such as stainless steel, cobalt, or titanium-based alloy resulting in stress shielding effect, some of these materials are designed in such a way to degrade or to be resorbed inside the body rather than removing the implant after its function is served. Here, Magnesium based biomaterials are the most suitable and used as a newly developed biodegradable material. Inherent mechanical properties of magnesium like properties of elastic and modulus rigidity which are very much same as to those of human bone, make it biocompatible. There is limited use of pure Mg due to its corrosive nature, but when formed an alloy or the composite the degradation property can be improved and making them a material of choice for implantation. This paper aim is to review the degradation rate and the methods to control it. Due to high degradation rate of the Mg, as compare to other biomaterials, our final goal is to maintain the balance between the gradual loss of material and mechanical strength during degradation, by providing the strength to the newly forming bone tissue. Mg-based alloy or composite has the potential to be used as a biomaterial without the need for a second surgery, once this goal is achieved.


NANO ◽  
2018 ◽  
Vol 13 (04) ◽  
pp. 1850038 ◽  
Author(s):  
Xingwang Zhou ◽  
Jun Yao ◽  
Ming Yang ◽  
Jiangquan Ma ◽  
Qingwei Zhou ◽  
...  

In this research, a series of novel MoSe2/SrTiO3 heterostructures were successfully prepared by a two-step hydrothermal method. The samples were characterized by XRD, UV-Vis, SEM, TEM, EDS and XPS. Results showed that the degradation of MO under UV is better than that under the visible light. And, MoSe2 loaded on SrTiO3 under UV irradiation demonstrated a higher catalytic activity. The degradation rate of methyl orange was 99.46% for MoSe2/SrTiO3 under the optimum loading weight (0.1[Formula: see text]wt.%). This is mainly because the combination of MoSe2 and SrTiO3 prevents electrons and holes recombination in SrTiO3 and [Formula: see text]O[Formula: see text] appears in the system. In general, MoSe2/SrTiO3 heterostructures have good environmental friendliness for photocatalytic degradation.


2013 ◽  
Vol 821-822 ◽  
pp. 1047-1050 ◽  
Author(s):  
Ya Jing Zhang ◽  
Xiao Hui Xi ◽  
Hai Long Jia ◽  
Dan Zhang

Magnesium alloys have the potential as a biodegradable material for orthopedic applications. However, severely corrosion in a physiological environment limits the clinical application of Mg alloys. Hydroxyapatite is the main composition of natural bone, it has excellent bioactivity and osteoconductivity. In this paper, the samples of AZ31 were ultrasonically cleaned using distilled water, and then the coating was formed on the surfaces of the samples by biomimetic process. The samples were subsequently immersed in the simulated body fluid (SBF) for the degradation test. The coatings were characterized by XRD, EDS and SEM. The results showed that hydroxyapatite (HA) coating was formed on the surface of AZ31 after 24h by biomimetic process; the HA coating greatly decreased the corrosion rate of AZ31 substrate; the degradation rate of samples can be controlled by closely adjusting the hydroxyapatite coating.


2021 ◽  
Author(s):  
Tao Li ◽  
Haoyang Sun ◽  
He Han ◽  
Chentao Zhang ◽  
Bin Li ◽  
...  

Abstract In the field of governing our “Plastic Planet”, polylactic acid (PLA) has been considered to be a promising and ecologically friendlier alternative to traditional petroleum-based plastics. However, PLA-based products degrade slowly in the natural environment, likely resulting in a large accumulation of PLA waste worldwide in the near future. Herein, we have incorporated artificially cultured diatom frustules (DFs) into PLA, and found an improvement of more than eightfold on the degradation rate, from more than 24 months to 3 months or even less, as compared with the pure PLA. Mechanistic investigations illustrate that DFs change the degradation behavior of PLA from surface erosion to bulk erosion by the induced microfibril crystals. Simulation analysis verifies that the unstable crack propagation inside the PLA matrix greatly accelerates the degradation. The method developed in this work provides an efficient way to achieve rapid and controllable degradation of biodegradable polymers for the urgent and widespread usage of green plastic productions.


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