Polydopamine-Inspired Surface Modification of Polypropylene Hernia Mesh Devices via Cold Oxygen Plasma: Antibacterial and Drug Release Properties

Mesh infection is a major complication of hernia surgery after polypropylene (PP) mesh implantation. Modifying the PP mesh with antibacterial drugs is an effective way to reduce the chance of infection, but the hydrophobic characteristic of PP fibers has obstructed the drug adhesion. Therefore, to prepare antimicrobial PP mesh with a stable drug coating layer and to slow the drug release property during the hernia repair process has a great practical meaning. In this work, PP meshes were coated by bio-inspired polydopamine (PDA), which can load and release levofloxacin. PP meshes were activated with cold oxygen plasma and then plasma activated PP fibers were coated with PDA. The PDA coated meshes were further soaked in levofloxacin. The levofloxacin loaded PP meshes demonstrate excellent antimicrobial properties for 6 days and the drug release has lasted for at least 24 h. Moreover, a control PP mesh sample without plasma treatment was also prepared, after coating with PDA and loading levofloxacin. The antimicrobial property was sustained only for two days. The maximum inhibition zone of PDA coated meshes with and without plasma treatment was 12.5 and 9 mm, respectively. On all accounts, the modification strategy can facilely lead to long-term property of infection prevention.

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Uji Ekstrak Bawang Bombay sebagai Anti Bakteri Gram Positif Staphylococcus aureus dengan Metode Difusi Cakram

Bioma Berkala Ilmiah Biologi ◽

10.14710/bioma.12.2.68-72 ◽

2012 ◽

Vol 12 (2) ◽

pp. 68

Author(s):

Wuryanti Wuryanti ◽

Nies Suci Mulyani ◽

Mukhammad Asy'ari ◽

Purbowatiningrum Ria Sarjono

Keyword(s):

Allium Cepa ◽

Human Life ◽

Antimicrobial Property ◽

Antimicrobial Properties ◽

Living Organism ◽

Inhibition Zone ◽

Antimicrobial Test ◽

Allium Cepa L ◽

Paper Disc

Microbe is a microscopic living organism which is closely linked to human life. One of pathogenic microorganisms such as Staphylococcus aureu,. may cause diseases. Sulfure of several plants are bioactive as antimicrobial. The properties of sulfure in Allium cepa L leads to an assumption that it has antimicrobial properties. Therefore, this study involved the antimicrobial test. The determination steps of antimicrobial Allium cepa L extract consisted of the Allium cepa L extract preparation, microbial regeneration and antimicrobial test. The antibacterial determination were performed by paper disc method. Based on the research data, determination of antimicrobial Allium cepa L extract resulted in inhibition zone area showed that the extract owned antimicrobial property.

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Evaluation of the Effect of Propolis Nanoparticles on Antimicrobial Properties and Shear Bond Strength of Orthodontic Composite Bonded to Bovine Enamel

Frontiers in Dentistry ◽

10.18502/fid.v16i2.1360 ◽

2019 ◽

Author(s):

Ahmad Sodagar ◽

Azam Akhavan ◽

Sepideh Arab ◽

Abbas Bahador ◽

Maryam Pourhajibagher ◽

...

Keyword(s):

Bond Strength ◽

Shear Bond Strength ◽

Antimicrobial Property ◽

Testing Machine ◽

Antimicrobial Properties ◽

Inhibition Zone ◽

Colony Growth ◽

Control Group ◽

Growth Inhibition Zone ◽

Bovine Enamel

We aimed to investigate the effects of propolis nanoparticles (prpNPs) on antimicrobial property and shear bond strength (SBS) of orthodontic composite bonded to bovine enamel. Materials and Methods: Sixty bovine teeth were randomly divided into five groups (n=12). PrpNPs were prepared at concentrations of 0% (control), 1%, 2%, 5%, and 10% in Transbond XT composite to bond stainless steel brackets to the teeth. SBS between brackets and teeth was measured using a universal testing machine. After debonding, the adhesive remnant index (ARI) on bracket bases was measured. In the microbial test, composites with the aforementioned concentrations of prpNPs were cured in metal discs. The bacteria included Streptococcus mutans (S. mutans), Streptococcus sanguinis (S. sanguinis), and Lactobacillus acidophilus (L. acidophilus), and antimicrobial effects of prpNPs were investigated by anti-biofilm, disc agar diffusion and eluted component tests. Results: The 10% prpNPs group showed the lowest SBS. Colony growths of S. mutans and S. sanguinis at all concentrations (except for 1%) was significantly lower than the control group. L. acidophilus colony growth was significantly reduced at 5% and 10% concentrations. Growth inhibition zone developed at 2%, 5%, and 10% concentrations for S. mutans and S. sanguinis. The lowest numbers of S. mutans and S. sanguinis colonies at all concentrations were observed on day 15. L. acidophilus colonies decreased significantly at all concentrations (except for 1%) until day 30.

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Quaternary ammonium salt of chitosan: preparation and antimicrobial property for paper

Open Medicine ◽

10.1515/med-2015-0081 ◽

2015 ◽

Vol 10 (1) ◽

Cited By ~ 12

Author(s):

Pengtao Liu ◽

Weisheng Meng ◽

Shuai Wang ◽

Yonghui Sun ◽

Muhammad Aqeel Ashraf

Keyword(s):

Ammonium Chloride ◽

Antimicrobial Property ◽

Antimicrobial Properties ◽

Inhibition Zone ◽

Antimicrobial Activities ◽

Inhibitory Effects ◽

Zone Method ◽

E Coli ◽

H Nmr ◽

Ft Ir

Abstract A series of 2-hydroxypropyltrimethyl ammonium chloride chitosan (HACC) was prepared by the reaction of chitosan with glycidyl trimethyl ammonium chloride. Structure of HACC was characterized by FT IR and 1H NMR spectroscopies, and it was proved that substitution reaction mainly occurs on the N element. Antimicrobial activities of HACC was examined against S. aureus, E. coli, and A. niger. Results indicatd that the inhibitory effects of HACC solutions were varied with HACC concentration, quaternization degrees, pH values, metal ions, and heat treatment. The antimicrobial properties of handsheets prepared from HACC were studied by the inhibition zone method, and the sheets had good antimicrobial properties against S. aureus and E. coli, and low inhibition rate against A. niger.

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Oxygen-plasma treatment-induced surface engineering of biomimetic polyurethane nanofibrous scaffolds for gelatin-heparin immobilization

e-Polymers ◽

10.1515/epoly-2017-0185 ◽

2018 ◽

Vol 18 (3) ◽

pp. 275-285 ◽

Cited By ~ 14

Author(s):

Farnaz Ghorbani ◽

Ali Zamanian

Keyword(s):

Drug Release ◽

Plasma Treatment ◽

Oxygen Plasma ◽

Surface Engineering ◽

Vascular Tissue ◽

Blood Compatibility ◽

Cellular Adhesion ◽

Oxygen Plasma Treatment ◽

Cellular Interactions ◽

Biological Potential

AbstractPolyurethane (PU) has been extensively used in vascular tissue engineering due to its outstanding mechanical performance and blood compatibility behavior. Here, biomimetic PU-based scaffolds were prepared using an electrospinning technique and gelatin-heparin was introduced as a surface modifier after oxygen plasma treatment to improve cell attachment and release an anticoagulation agent. Morphology, Fourier transform infrared (FTIR) spectroscopy, compression strength, swelling and biodegradation ratio, drug release level and cellular interactions were evaluated. According to the scanning electron microscopy (SEM) micrographs, gelatin-heparin immobilized PU nanofibers exhibited a smooth surface and a bead free structure that nanofibers distributed in the range of 300–1000 nm. The mechanical strength of constructs, swelling and biodegradation ratio, and drug release level illustrated higher values for oxygen plasma-treated samples compared with bilayered scaffolds. Cellular adhesion and biocompatibility ameliorated after plasma treatment. All the mentioned findings indicated the initial physicomechanical and biological potential of biomimetic PU-based fibers in the improvements of vascular scaffolds.

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Fabrication and Characterization of Shellac/2-Isopropyl-5-Methylphenol Composite Film Patch: Physical and Antimicrobial Properties

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.747.31 ◽

2013 ◽

Vol 747 ◽

pp. 31-34 ◽

Cited By ~ 1

Author(s):

Thanachod Thammachat ◽

Sitthiphong Soradech

Keyword(s):

Mechanical Properties ◽

Physicochemical Properties ◽

Composite Film ◽

Antimicrobial Property ◽

Composite Films ◽

Antimicrobial Properties ◽

Inhibition Zone ◽

Free Film ◽

Antimicrobial Film ◽

Ft Ir

The purpose of this study was to evaluate the physicochemical properties and antimicrobial activity of shellac/2-isopropyl-5-methylphenol composite film patch. 2SHL was applied as a matrix film forming agent for antimicrobial film patch. The samples of IPMP loaded within SHL were prepared in a free film by the casting method. The SHL/IPMP composite film patch was characterized on the physicochemical properties such as: FTIR spectroscopy,X-ray diffraction and mechanical properties. Antimicrobial property was assessed against Staphylococcus aureus and E.coli. The results demonstrated that all films were easily prepared. However, the mechanical properties, XRD and FT-IR of composite film patch were dependent on the composition of blending film while the melting and solubility of film showed no change. The % elongation of the films was increased as the fraction of IPMP increased to 20%, resulting in more flexibility of shellac. The composite film could be formed by the hydrogen bonds, giving the change in physicochemical properties of films. These results were supported by the change in FT-IR and XRD pattern of composite film. The SHL/IPMP composite films exhibited the inhibition zone at 5% concentration of IPMP or more concentration. The diameter of inhibition zone was increased as increasing the percentage of IPMP. The result suggested that antimicrobial SHL/IPMP composite film patch could be achieved. In conclusion, shellac could be a promising polymer for fabrication of antimicrobial film patch, contributing to the widely used as medical products for wound dressing.

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Pharmacognostical fingerprinting and selective bioactivity studies of Solanum glaucophyllum Desf.

Journal of Traditional and Folk Practices ◽

10.25173/jtfp.2018.6.1.87 ◽

2018 ◽

Vol 6 (1) ◽

Author(s):

Anindya Sundar Ray ◽

Suman Kalyan Mandal ◽

Chowdhury Habibur Rahaman

Keyword(s):

Medicinal Plant ◽

Radical Scavenging ◽

Ethanol Extract ◽

Inhibition Zone ◽

Phytochemical Analysis ◽

Antimicrobial Studies ◽

Maximum Inhibition ◽

Crude Drugs ◽

Phytochemical Studies ◽

Dpph Radical Scavenging

Solanum glaucophyllum Desf. (Solanaceae) is traditionally used for curing several health conditions in both human and domesticated animals. There is no data available regarding pharmacognostic standardization and pharmacological activity of this less known medicinal plant. Therefore, the aim of the present work is to prepare pharmacognostic fingerprints of crude drugs obtained from the leaf and stem parts of S. glaucophyllum. Apart from this detailed phytochemical analysis, antioxidant and antimicrobial studies have also been carried out. Pharmacognostic study revealed that the leaves are amphistomatic and stomata are strictly of anisocytic type. Values of stomatal index, palisade ratio, ash content of the investigated parts are found distinct and can be used as pharmacognostic standards for evaluation of crude drugs of this medicinal plant. Phytochemical studies of the leaf and stem parts indicated that phenolics, flavonoids, tannins and alkaloids are present in quite impressible amount. Curcumin content in stem was found very high through HPLC analysis. In DPPH radical scavenging assay, the stem part showed significant antioxidant potential. Ethanol extract of stem produced maximum inhibition zone (11mm) against Pseudomonas aeruginosa at the concentration of 50 mg/ml among five test microorganisms. Some pharmacognostic features recorded in this study as diagnostic ones will help in proper identification of this ethnomedicinal plant in its fresh as well as dried form. On the other hand preliminary phytochemical, antioxidant and antimicrobial studies highlight the S. glaucophyllum as a promising candidate for bioprospecting.

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High Breakdown Voltage GaN HEMT Device Fabricated on Self-Standing GaN Substrate

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.347-350.1535 ◽

2013 ◽

Vol 347-350 ◽

pp. 1535-1539

Author(s):

Jian Jun Zhou ◽

Liang Li ◽

Hai Yan Lu ◽

Ceng Kong ◽

Yue Chan Kong ◽

...

Keyword(s):

Plasma Treatment ◽

Breakdown Voltage ◽

Oxygen Plasma ◽

Cutoff Frequency ◽

Chemical Vapor ◽

Current Gain ◽

Organic Chemical ◽

Oxygen Plasma Treatment ◽

Gan Hemt ◽

High Breakdown Voltage

In this letter, a high breakdown voltage GaN HEMT device fabricated on semi-insulating self-standing GaN substrate is presented. High quality AlGaN/GaN epilayer was grown on self-standing GaN substrate by metal organic chemical vapor deposition. A 0.8μm gate length GaN HEMT device was fabricated with oxygen plasma treatment. By using oxygen plasma treatment, gate forward working voltage is increased, and a breakdown voltage of more than 170V is demonstrated. The measured maximum drain current of the device is larger than 700 mA/mm at 4V gate bias voltage. The maximum transconductance of the device is 162 mS/mm. In addition, high frequency performance of the GaN HEMT device is also obtained. The current gain cutoff frequency and power gain cutoff frequency are 19.7 GHz and 32.8 GHz, respectively. A high fT-LG product of 15.76 GHzμm indicating that homoepitaxy technology is helpful to improve the frequency performance of the device.

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Improved antimicrobial property and controlled drug release kinetics of silver sulfadiazine loaded ordered mesoporous silica

Journal of Asian Ceramic Societies ◽

10.1016/j.jascer.2016.05.005 ◽

2016 ◽

Vol 4 (3) ◽

pp. 282-288 ◽

Cited By ~ 13

Author(s):

Suman Jangra ◽

Sunita Devi ◽

Vijay K. Tomer ◽

Vinod Chhokar ◽

Surender Duhan

Keyword(s):

Drug Release ◽

Mesoporous Silica ◽

Release Kinetics ◽

Antimicrobial Property ◽

Controlled Drug Release ◽

Silver Sulfadiazine ◽

Ordered Mesoporous Silica ◽

Drug Release Kinetics ◽

Ordered Mesoporous ◽

Kinetics Of

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Valence variation of phase-pure M1 MoVNbTe oxide by plasma treatment for improved catalytic performance in oxidative dehydrogenation of ethane

RSC Advances ◽

10.1039/c5ra16517b ◽

2015 ◽

Vol 5 (111) ◽

pp. 91295-91301 ◽

Cited By ~ 7

Author(s):

Xin Chen ◽

Qianli Yang ◽

Bozhao Chu ◽

Hang An ◽

Yi Cheng

Keyword(s):

Surface Modification ◽

Metal Oxide ◽

Plasma Treatment ◽

Oxidative Dehydrogenation ◽

Oxidation State ◽

Active Sites ◽

Oxygen Plasma ◽

Catalyst Surface ◽

Catalytic Performance ◽

Phase Pure

This work presents a new method of catalyst surface modification by using oxygen plasma to change the oxidation state of active sites in metal oxide catalysts.

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