scholarly journals Are Congenital Cervical Block Vertebrae a Risk Factor for Adjacent Segment Disease? A Retrospective Cross-Sectional CT and MR Imaging Study

Diagnostics ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 90
Author(s):  
Cornelius Jung ◽  
Patrick Asbach ◽  
Stefan M. Niehues

Adjacent segment disease (ASDI) is a well-described complication of spinal fusion surgery that may ultimately lead to spinal stenosis and repeated surgical intervention. Although congenital block vertebrae also present with degenerative changes in the adjacent segments, this has not yet been systematically investigated. The aim of this study was to assess the presence and degree of ASDI in congenital cervical block vertebrae. Methods: A total of 51 patients with congenital vertebral fusion in one cervical segment were analysed in this IRB-approved retrospective cross-sectional study using available CT/MR imaging. Exclusion criteria were prior spinal surgery and the presence of additional hereditary abnormalities. We assessed the severity of degenerative changes using a sum score. The sum score for adjacent and non-adjacent segments was then divided by the highest possible degeneration score, which resulted in a ratio of severity for adjacent and remaining segments (ranging from 0 to 1). Results: Overall, 35 of 51 patients (68.6%) showed evidence of ASDI, and 34 of 51 patients (66.7%) also showed degenerative changes in the remaining segments. The severity score was significantly higher (p = 0.025) in the segments adjacent to the congenital block vertebrae (mean value 0.307) compared to the non-adjacent segments (mean value 0.188). Conclusions: Our results suggest that ASDI is also caused by congenital block vertebrae of the cervical spine.

2004 ◽  
Vol 100 (1) ◽  
pp. 2-6 ◽  
Author(s):  
Vaijayantee Kulkarni ◽  
Vedantam Rajshekhar ◽  
Lakshminarayan Raghuram

Object. The authors studied whether cervical spine motion segments adjacent to a fused segment exhibit accelerated degenerative changes on short-term follow-up magnetic resonance (MR) imaging. Methods. Preoperative and short-term follow-up (mean duration 17.5 months, range 10–48 months) cervical MR images obtained in 44 patients who had undergone one- or two-level corpectomy for cervical spondylotic myelopathy were evaluated qualitatively and quantitatively. The motion segment adjacent to the fused segment and a segment remote from the fused segment were evaluated for indentation of the thecal sac, disc height, and sagittal functional diameter of the spinal canal on midsagittal T2-weighted MR images. Thecal sac indentations were classifed as mild, moderate, and severe. New indentations of the thecal sac of varying severity (mild in 17 patients [38.6%], moderate in 10 [22.7%], and severe in six [13.6%]) had developed at the adjacent segments in 33 (75%) of 44 patients. The degenerative changes were seen at the superior level in 11 patients, inferior level in 10 patients, and at both levels in 12 patients and resulted from both anterior and posterior element degeneration in the majority (23 [69.6%]) of patients. The remote segments showed mild thecal sac indentations in seven patients and moderate indentations in two patients (nine [20.5%] of 44). Compared with the changes at the remote segment, the canal size was significantly decreased at the superior adjacent segment by 0.9 mm (p = 0.007). No patient sustained a new neurological deficit due to adjacent-segment changes. Conclusions. On short-term follow-up MR imaging, levels adjacent to the fused segment exhibited more pronounced degenerative changes (compared with remote levels) in 75% of patients who had undergone one- or two-level central corpectomy.


Author(s):  
Eglė Slabšinskienė ◽  
Andrej Gorelik ◽  
Aistė Kavaliauskienė ◽  
Apolinaras Zaborskis

Although burnout has been described as a serious hazard for personal and professional lives and has been surveyed among dentists in many countries, no study has been published regarding burnout among dentists in Lithuania. This study aimed to evaluate the burnout level among Lithuanian dentists and its association with demographic variables, job satisfaction, and other job-related variables. The data were collected among dentists online or during professional conferences while using an anonymous questionnaire (n = 380). The Maslach Burnout Inventory (MBI) was used to evaluate the burnout level. A Poisson regression was applied for the analysis of relationships between variables. We observed that 42.3% of the respondents had a high emotional exhaustion (EE) (95% confidence interval (CI): 37.4–42.3%), while 18.7% (95% CI: 15.0–22.9%) and 28,2% (95% CI: 23.4–32.6%) had high depersonalization (DP) and low personal accomplishment (PA), respectively. Nonetheless, 15.3% (95% CI: 11.8–18.9%) of the study population experienced a high level of overall burnout. An original job satisfaction index was elaborated. It was significantly associated with sum scores of all burnout dimensions: with the EE sum score (Ratio of Sum Score Means (RSSM) 1.54; 95% CI: 1.46–1.62), DP sum score (RSSM 1.59; 95% CI: 1.45–1.74), and PA sum score (RSSM 0.88; 95% CI: 0.84–0.92). It was concluded that Lithuanian dentists can be characterised by high burnout intensity and high prevalence of burnout, being especially evident in emotional exhaustion. The dentist with low job satisfaction appeared to be the most vulnerable to all burnout dimensions.


2021 ◽  
Vol 8 (3) ◽  
pp. 147-152
Author(s):  
Mosmi Lomi ◽  
Jonathan Daniel M

Determining gender is one of the most important procedure in forensics. Teeth are made of the most enduring mineralized tissues in the body, as such, they have an extraordinary resistance to putrefaction and the effects of external agents (physical, thermal, mechanical, chemical or biological) which makes them invaluable material for anthropological, genetic, odontologic and forensic examinations.i)To assess the degree of sexual dimorphism in maxillary canine using maxillary canine index, maxillary first molar and central incisor using mesiodistal (MD) and buccolingual/buccopalatal (BL) dimensions of the crown. ii) To determine the accuracy of maxillary canine index, first molar and central incisor dimensions (mesiodistal and buccolingual/buccopalatal) in determining sex.This study consisted of total 30 participants (males=15, females=15) of age group ranging from 20 to 35 yrs. Measurement of dimensions of selected teeth were performed on maxillary cast using digital Vernier caliper, resolution 0.01mm. Data thus obtained were analyzed statistically.The mean values of all the measurements in males were greater than females. There was statistical significant difference in mean value of bucco-lingual width of molar, mesiodistal width of canine (on left side, right side and average) and the inter-canine distance between males and females. The buccolingual width of molar showed the highest % of sexual dimorphism (5.33%) and the mesiodistal width of molar showed the least % of dimorphism (0.7%). Bucco-lingual width of molar posed the highest prediction accuracy for gender determination. We conclude that buccolingual width of maxillary first molar can be used to predict the gender when only teeth of maxillary arch are available for forensic examination.


2021 ◽  
Vol 15 (12) ◽  
pp. 3307-3309
Author(s):  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Muhammad Sohail Tareen ◽  
Nosheen Sikander Baloch

Background: Pregnancy induced hypertension is a fetal disease resulting into morbidity and mortality of female as well as its neonate. Objective: To find the incidence of pregnancy induced hypertension in Pakistani women. Study Design: Cross sectional study Place and Duration of the Study: Department of Obstetrics & Gynaecology, Sandeman Provincial Hospital, Quetta from 1st March 2019 to 31st March 2021. Methodology: Seven hundred and twenty eight females were identified with pregnancy induced hypertension from all the pregnant women attending the outdoor were enrolled. Each female was checked for their protein urea as well as systolic and diastolic blood pressure according to standard operating protocol. Socio-demographic, clinical and family history were documented. Results: Among all pregnant women, 150 were identified as pregnancy induced hypertensive with a 20.6% incidence of pregnancy induced hypertension. The mean value systolic blood pressure value was 144.3±5.2 and of diastolic as 83.1±5.2 in pregnancy induced hypertension women. Conclusion: Family history, obesity and renal diseases are the main factors associated with pregnancy induced hypertension with an incidence of 20.6% among pregnant women. Keywords: Pregnancy induced hypertension, Body mass index, Pregnant women, Hypertension


2021 ◽  
Vol 8 (2) ◽  
pp. 5-12
Author(s):  
Rizwana Abdul Hye ◽  
Bindiya Gisuthan ◽  
Indira Kariveettil

Introduction: Leishman stain has been used as the stain of choice for peripheral blood films since many decades .But it has a disadvantage of consuming 15 minutes for the procedure alone thereby increasing the turn around time of peripheral smear reporting. In this study modified Leishman stain was made by adding phenol to conventional Leishman to reduce the staining time to 3 minutes without interfering with the quality of stain. Aim: To study the quality of modified Leishman stain in comparison with conventional preparation on peripheral blood smears. Materials and Methods: The present cross-sectional study was carried out in Central Haematology laboratory of a tertiary health care centre in Southern India. A pilot study was done to determine the ideal ratio of phenol to Leishman powder in preparing modified stain without compromising the staining quality. After obtaining consent, the blood sample was collected in anticoagulated vials. Sample size was calculated to be 85.Two thin wedge smears were prepared from each sample and one was stained with conventional Leishman stain and other with modified Leishman stain. The staining characteristics were assessed and scored by an experienced pathologist in terms of 6 parameters- RBC pattern, nuclear pattern, neutrophil granules, eosinophil granules, platelets and background staining. The grades were 1, 2, 3 & 4 (poor, satisfied, good and excellent). Smears each with grades 2, 3 and 4 were selected for study. The results were analysed by Statistical Package for the Social Sciences (SPSS) software version 16.0. Result: The mean value for the staining quality using conventional method was 4.73 and for modified method was 5.39, and the total score possible is 6. Photomicrograph showed excellent results with modified Leishman stain. Thus from these values we can interpret that modified method gave much more acceptable results than that of conventional method. Conclusion: Unlike the conventional method which requires a total of 15 minutes, to complete the staining process, modified Leishman staining techniques takes only 3 minutes. Blood films can be stained within a short period of time thus aiding in rapid diagnosis and treatment of patients. Keywords: Leishman stain, Modified Leishman stain, Phenol.


2018 ◽  
Vol 10 (1) ◽  
pp. 18-21 ◽  
Author(s):  
Sultana Amena Ferdoucy ◽  
Md Anower Hussain Mian ◽  
Nasrin Akhter ◽  
Md Shafiqul Alam ◽  
MA Sadek

Aims: Degenerative joint diseases and decreased bone mass i.e.  osteoporosis are two common age related skeletal disorders  responsible for pain and disability. Bangladesh has a high incidence  of osteoporosis and the incidence particularly in women, occurs  among a relatively younger age group than in the developed world.  However little is known about the correlation between degenerative  changes and osteoporosis in lumbar spine of elderly women. The  purpose of this study was to clarify this relationship in elderly women  of Dhaka, Bangladesh.  Methods: A cross-sectional study was conducted at the department  of radiology and imaging of Bangladesh institute of research and  rehabilitation in diabetes, endocrine and metabolic disorders  (BIRDEM), Dhaka during the period of 1st January, 2009 to 31st  December, 2010. DEXA scan of spine and BMD measurement were  done at a renowned private hospital of Dhaka. Total 63 elderly female  aged between 50-75 years were randomly selected for this study.  Results: An inverse relationship between osteoporosis and  spondylosis in postmenopausal women as evaluated by bone  mineral density and semiquantitative scoring of spinal degeneration  was observed. A significant negative correlation (r=-0.53:p<0.05)  was found between T-score and grade. DOI: http://dx.doi.org/10.3329/cdcj.v10i1.13740 City Dent. Coll. J Volume-10, Number-1, January-2013


Author(s):  
Carla S. PALUDO ◽  
Amanda SACHETTI ◽  
Maiara S. PAIXÃO

Objective: To evaluate the frequency of use of oral contraceptives and other risk factors among women with ischemic stroke seen at a hospital in the northern region of the state of Rio Grande do Sul. Methods: Prospective, cross-sectional study. The population was characterized by patients admitted with a diagnosis of ischemic stroke during a period from March to August 2019 and the sample by female patients found in the population. The data were collected through an individual interview using a questionnaire developed by the researchers and tabulated for further analysis. All analyzes were performed using the statistical program Bioestat 5.0, considering p = 0.05. Results: In the characterization of the sample, an average age of 68.2 years was observed. The occurrence of gender was 52.4% for women. The mean hospital stay was 12.2 ± 8.91 days. Outcome of hospital discharge was 89.1%. The mean value of body mass index was 25 ± 4.89 kg / m², with an average of 27.4 kg / m² in patients who used oral contraceptives and 25.23 kg / m² in patients who did not use oral contraceptives. The sample had a 34.5%incidence of oral contraceptive use. The average age of those who used oral contraceptives was 62.4 years and of the patients who did not use it was 70.3 years. Conclusion: The study showed a high use of oral contraceptives in the sample, with percentage values very close to other factors evaluated, thus showing itself as a probable risk factor for the development of ischemic stroke.


2021 ◽  
Vol 17 (34) ◽  
pp. 44
Author(s):  
Aklesso Bagny ◽  
Lidawu Roland-Moise Kogoe ◽  
Laconi Yeba Kaaga ◽  
Late Mawuli Lawson-Ananissoh ◽  
Debehoma Redah ◽  
...  

Objectif : Décrire les aspects épidémiologique, clinique et pronostique associés aux étiologies des hémorragies digestives hautes au CHU Campus de Lomé Patients et méthode: Etude transversale à collecte rétrospective, à visée descriptive et analytique menée du 1er Janvier 2014 au 31 Décembre 2019. Le seuil de significativité était retenu pour p<0,05. Résultats: Deux cent cinquante et un patients avaient été inclus. L’hémorragie était d’origine hypertensive portale chez 69 patients (27,71%) ; ulcéreuse gastro-duodénale chez 100 patients (39,84%). Chez 25 patients (9,96%), la fibroscopie oesogastroduodénale était normale. Une rupture de varices oesophagiennes était retrouvée chez 98,55% des patients présentant une hypertension portale. Les ulcères gastroduodénaux représentaient 54,94% des hémorragies digestives hautes d’origine non hypertensive portale. La valeur moyenne du score de Rockall était de 4(±1) chez les patients présentant une hémorragie d’origine hypertensive et de 3(±1) chez les patients avec hémorragie non hypertensive portale (p<0,001). La valeur moyenne du score de Glasgow-Blatchford était de 10(±3) chez les patients présentant une hémorragie d’origine hypertensive et 9(±3) chez les patients avec hémorragie digestive haute d’origine non hypertensive (p<0,001). La récidive hémorragique et le décès étaient survenus chez les patients présentant un saignement d’origine hypertensive portale dans respectivement 54,84% (p<0,001) et 71,42% (p<0,001). Conclusion: Les lésions inflammatoires aiguës et chroniques représentent la première étiologie des hémorragies digestives hautes dans le service d’Hépato-gastroentérologie du CHU Campus. Ces hémorragies sont associées à la prise de médicaments gastrotoxiques et à un moindre risque de récidive hémorragique et de décès. Objective: To describe epidemiological et prognostic outcomes associated with etiologies upper gastrointestinal bleeding in Campus Teaching Hospital of Lome Patients and method: Cross-sectional study with retrospective collection, descriptive and analytical aim carried out from January 1, 2014 to December 31, 2019. Results: Two hundred and one patients were included. The hemorrhage was of portal hypertensive origin in 69 patients (27.71%); peptic ulcer in 100 patients (39.84%). In 25 patients (9.96%), the oesogastroduodenal fibroscopy was normal. Ruptured esophageal varices were found in 98.55% of patients with portal hypertension. Peptic ulcers accounted for 54.94% of upper GI bleeding of non-portal hypertensive origin. The mean value of the Rockall score was 4(±1) in patients with hemorrhage of hypertensive origin and 3(±1) in patients with non-portal hypertensive hemorrhage (p<0.001). The mean Glasgow-Blatchford score was 10(±3) in patients with hemorrhage of hypertensive origin and 9(±3) in patients with upper GI hemorrhage of nonhypertensive origin (p<0.001). Hemorrhagic recurrence and death occurred in patients with bleeding of hypertensive origin in 54.84% (p<0.001) and 71.42% (p<0.001) respectively. Conclusion: Acute and chronic inflammatory lesions represent the first etiology of upper GI bleeding in the Gastroenterology Department of the Campus Teaching Hospital of Lome. These hemorrhages are associated with the use of gastrotoxic drugs and with a lower risk of recurrence of hemorrhage and death.


Author(s):  
Ivan Buntara ◽  
Yohanes Firmansyah ◽  
Hendsun Hendsun ◽  
Ernawati Su

Gastroesophageal Reflux Disease (GERD) is a form of gastrointestinal motility disorder, where stomach contents reenter the esophagus and oral cavity, causing symptoms and complications. GERD is a condition that is quite often experienced, where the prevalence estimated at 8 - 33% worldwide. One of the suspected cause of  GERD is Ramadan fasting, which has been routinely carried out by Muslim groups. This study aims to prove whether Ramadan fasting triggers GERD. A cross-sectional study (survey) conducted online via Google form on the last three days of the fasting month (21 May 2020 - 23 May 2020). The variables in this study were respondents who fasted Ramadan and those who did not fast, also the total value of the GERD-Q questionnaire along with the final conclusions. Statistical analysis using Chi square with Yates Correction and Independent T-test with Mann Whitney Alternative Test. 311 respondents met the inclusion criteria. The results of Mann Whitney statistical test found that there was no difference in the mean value of the total GERD-Q questionnaire between the fasting and non-fasting groups (p-value: 0.313). Pearson Chi Square with Yates Correction results found no significant relationship between fasting and incidence of GERD (p-value: 0.552), although clinically there was a possibility of fasting had a risk of 1,228 (95% CI: 0.772 -2,088) times to trigger GERD incident.as Conclusion, Ramadan fasting has not been shown to improve GERD symptoms. Further research needs to be done through longitudinal studies. Keywords: GERD; digestion; Ramadan fastingABSTRAKGastroesophageal Reflux Disease (GERD) merupakan suatu bentuk gangguan motilitas saluran cerna, dimana isi lambung masuk kembali ke dalam esofagus dan rongga mulut, sehingga menyebabkan gejala dan komplikasi. GERD merupakan kondisi yang cukup sering dialami, dimana prevalensinya diperkirakan mencapai 8 – 33% di seluruh dunia. Salah satu faktor yang diperkirakan sebagai penyebab GERD adalah puasa Ramadhan yang selama ini rutin dijalankan oleh kelompok Muslim. Penelitian ini bertujuan untuk membuktikan apakah puasa Ramadhan mencetuskan kejadian GERD. Penelitian potong lintang (survei) yang dilaksanakan secara online melalui google form pada tiga hari terakhir bulan puasa Ramadhan 2020 (21 Mei 2020 – 23 Mei 2020). Variabel dalam penelitian ini adalah responden yang berpuasa Ramadhan maupun yang tidak berpuasa Ramadhan dan nilai total kuesioner GERD-Q beserta kesimpulan akhir dari kuesioner GERD-Q. Analisis statistik menggunakan uji statistik Chi square with Yates Correction dan Independent T-test dengan Uji Alternatif Mann Whitney. 311 responden memenuhi kriteria inklusi. Hasil uji statistik Mann Whitney tidak terdapat perbedaan rerata nilai total kuesioner GERD-Q antara kelompok yang berpuasa dan tidak berpuasa (p-value : 0,313). Hasil uji statistik Pearson Chi Square with Yates Correction didapatkan hubungan yang tidak bermakna antara berpuasa dengan kejadian GERD (p-value : 0,552), walaupun secara klinis ditemukan adanya kemungkinan yang berpuasa lebih berisiko 1,228 (CI 95% : 0,772 -2,088) kali untuk mencetuskan kejadian GERD. Sebagai kesimpulan, Puasa Ramadhan tidak terbukti meningkatkan gejala-gejala GERD. Perlu dilakukan penelitian lebih lanjut melalui studi longitudinal untuk tindak lanjut hasil penelitian ini.


2021 ◽  
Author(s):  
Anemut Tilahun Mulu ◽  
Getachew Yideg Yitbarek ◽  
Fitalew Tadele Admasu ◽  
Chalachew Yenew Denekew ◽  
Biruk Demissie Melese

Abstract Background: HAART has been reported to be associated with a number of side effects in human immunodeficiency virus patients among which dyslipidemia is a common metabolic disorder. Methods: A facility based comparative cross-sectional study among 228 HIV positive persons was conducted from July to August 2020. Socio-demographic and clinical data were collected using structured questionnaires. Fasting venous blood sample was drawn for Lipid profiles and CD4 cell determination. Anthropometric measurement was done. Data was analyzed using SPSS version 22 for windows. Result: A total of 228 HIV patients were enrolled in the study. Prevalence of dyslipidemia in HAART naive and on HAART HIV positive persons was 61(53.5%) and 84 (73.7%), respectively. The prevalence of TC≥200 mg/dl was 50% and 30%; HLD-c<40 mg/dl was 43.8% and 36%; LDL-c≥130mg/dl was 48.3% and 28.1%; and TG≥150 mg/dl 59.6% and 39% among on HAART and HAART naïve, respectively. Age greater than 40 years (AOR = 3.27, 95% C.I: 1.47 - 7.25), blood pressure ≥ 140/90 (AOR = 16.13, 95% C.I: 5.81 - 44.75), being on HAART (AOR = 2.73, 95 % C.I: 1.35 - 5.53) and body mass index > 25kg/m2 (AOR = 1.92, 95 % C.I: 1.20 - 4.81) were identified as determinants of dyslipidemia. Conclusion: The mean value of lipid profile was significantly higher among HIV positive clients on HAART as compared to those HAART naïve HIV positive clients.


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