scholarly journals Comparison of Postoperative Bleeding between Application of Polyglycolic Acid Sheet and Primary Closure in Tongue Cancer Patients with Partial Glossectomy

2020 ◽  
Vol 8 (3) ◽  
pp. 85
Author(s):  
Satoshi Fukuzawa ◽  
Kenji Yamagata ◽  
Yuuma Hasegawa ◽  
Naomi Ishibashi-Kanno ◽  
Fumihiko Uchida ◽  
...  
Keyword(s):  
Antithrombotic Therapy ◽  
Primary Closure ◽  
Tongue Cancer ◽  
Postoperative Bleeding ◽  
Predictor Variable ◽  
Polyglycolic Acid ◽  
Outcome Variable ◽  
Polyglycolic Acid Sheet ◽  
Significant Difference ◽  
Partial Glossectomy

The technique of covering a mucosal defect with fibrin glue and a polyglycolic acid sheet (MCFP) for the resection of mucosa is applied in oral cancers. The MCFP technique for partial glossectomy provides faster relief from postoperative pain and the prevention of scar contracture, unlike primary closure. However, it has a major complication of postoperative bleeding. This study sought to compare postoperative bleeding between the MCFP technique and primary closure. We designed a retrospective study with a cohort of 57 patients who underwent partial glossectomy with the MCFP technique or primary closure. Our primary predictor variable was the wound closure procedure (primary closure or the MCFP technique). The primary outcome variable was postoperative bleeding, and the other variables were patient characteristics, excision area and depth, tooth contact for the wound, and antithrombotic therapy. Statistical evaluation was performed with Pearson’s chi-squared test, Welch’s t-test, and multiple logistic regression. P < 0.05 was considered statistically significant. The MCFP technique was selected for cases with a large excision area (1433 vs. 963 mm2, P = 0.029). Total postoperative bleeding occurred in 10 of 57 patients (MCFP technique: 7 of 37 cases; primary closure: 3 of 20 cases). There was no significant difference in bleeding between the two groups (P = 0.71). Postoperative bleeding was significant in patients with antithrombotic therapy (MCFP: 40% vs. primary closure: 2%, P = 0.0024). Postoperative bleeding timing was significantly different in the MCFP technique (6.4 days) from that of primary closure (1 day; P = 0.0076). Postoperative bleeding was not associated with the MCFP technique or primary closure. However, postoperative bleeding with the MCFP technique occurred later than that with primary closure. The MCFP technique is not recommended for patients on antithrombotic therapy.

scholarly journals Application of polyglycolic acid sheet and fibrin glue spray for partial glossectomy: Comparison with artificial dermis

2011 ◽  
Vol 57 (7) ◽  
pp. 394-400 ◽  
Author(s):  
Junichiro TAKEUCHI ◽  
Masahiro UMEDA ◽  
Maho MURATA ◽  
Yasumasa KAKEI ◽  
Akira KIMOTO ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Artificial Dermis ◽  
Partial Glossectomy

Usefulness of Fibrin Glue and Polyglycolic Acid Sheet following Partial Glossectomy in the Elderly

2016 ◽  
Vol 145 (0) ◽  
pp. 74-74
Author(s):  
Takao Makise ◽  
Junichiro Ohori ◽  
Keiichi Miyashita ◽  
Hiroyuki Iuchi ◽  
Yuichi Kurono
Keyword(s):  
Fibrin Glue ◽  
The Elderly ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

Clinical Evaluation of Application of Polyglycolic Acid Sheet and Fibrin Glue Spray for Partial Glossectomy

2013 ◽  
Vol 71 (2) ◽  
pp. e126-e131 ◽  
Author(s):  
Junichiro Takeuchi ◽  
Hiroaki Suzuki ◽  
Maho Murata ◽  
Yasumasa Kakei ◽  
Shinshou Ri ◽  
...  
Keyword(s):  
Fibrin Glue ◽  
Clinical Evaluation ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

scholarly journals The Study of Relationship between Internet Addictions and Aggression among Teenagers

2017 ◽  
Vol 3 (4) ◽  
pp. 7-13
Author(s):  
Raja Ahmed Jamil ◽  
Bibi Asma Khatoon ◽  
Andleeb Akhtar ◽  
Assad Rahman
Keyword(s):  
Psychometric Properties ◽  
Internet Addiction ◽  
Predictor Variable ◽  
Outcome Variable ◽  
Test Analysis ◽  
Significant Difference ◽  
Males And Females ◽  
Level Of Significance ◽  
The Relationship ◽  
Positive Effect

The study was designed to investigate the relationship between internet addiction and aggression and to establish the psychometric properties of the scales. A standardized questionnaire was used to collect information about level of internet addiction and aggression among teenagers. To establish the psychometric properties, sample (n=200, having age 15-19 years) was selected from different schools and colleges of Haripur city. The results of research showed that the predictor variable internet addiction (β=.88) had a very high significant positive effect on outcome variable aggression with the level of significance p≤.000. The t-Test analysis showed significant difference between males and females on both variables.

Usefulness of Fibrin Glue and Polyglycolic Acid Sheet following Partial Glossectomy in the Elderly

2015 ◽  
Vol 108 (9) ◽  
pp. 709-712
Author(s):  
Takao Makise ◽  
Junichiro Ohori ◽  
Keiichi Miyashita ◽  
Hiroyuki Iuchi ◽  
Yuichi Kurono
Keyword(s):  
Fibrin Glue ◽  
The Elderly ◽  
Polyglycolic Acid ◽  
Polyglycolic Acid Sheet ◽  
Partial Glossectomy

Schneiderian Membrane Thickness Is Increased in Patients With Cleft Lip and Palate

2019 ◽  
Vol 57 (3) ◽  
pp. 296-301
Author(s):  
Isabelle Citron ◽  
Christine Lee ◽  
Carly E. Calabrese ◽  
Bonnie L. Padwa
Keyword(s):  
Cleft Lip ◽  
Cleft Lip And Palate ◽  
Tertiary Care ◽  
Predictor Variable ◽  
Outcome Variable ◽  
Membrane Thickness ◽  
Schneiderian Membrane ◽  
Significant Difference ◽  
Mucosal Thickness ◽  
Age And Sex

Objective: Patients with cleft lip and palate (CLP) are more likely to have sinusitis. The purpose of this study is to determine whether patients with CLP have thickening of the Schneiderian membrane. Specific aims were to (1) compare Schneiderian membrane thickness in patients with CLP to noncleft controls, (2) evaluate whether membrane thickening is associated with cleft side in patients with unilateral cleft lip and palate (UCLP), and (3) evaluate if age and sex are predictors of mucosal thickening. Design: Case–control study. Setting: Tertiary care center. Patients: Patients with CLP and controls. Main Outcome Measure: The primary outcome variable was maximum Schneiderian membrane thickness measured on cone beam computed tomography. The primary predictor variable was the presence of a cleft. Additional variables were cleft phenotype, age, and sex. Results: There were 225 patients with CLP and 93 controls. Median mucosal thickness was 2.4 mm in cleft group and 0.0 mm in controls ( P = .006). In cleft group, 56.7% of sinuses had mucosal thickness >2.0 mm compared to 38.2% in controls ( P = < .004). Pathologic membrane thickening (>4.0 mm) was significantly higher in cleft group ( P = .005). No statistically significant difference in mucosal thickness between cleft and noncleft sides in patients with UCLP. Linear regression showed no association between age or sex and Schneiderian membrane thickness. Conclusion: Schneiderian membrane thickening is more common in patients with CLP and is not associated with the side of the cleft in patients with UCLP.

scholarly journals Can Low Level Laser Therapy Benefit Bone Regeneration in Localized Maxillary Cystic Defects? - A Prospective Randomized Control Trial

2016 ◽  
Vol 4 (4) ◽  
pp. 720-725 ◽  
Author(s):  
Ahmed Abbas Zaky ◽  
Hanaa M. Elshenawy ◽  
Tarek Abdel Hamed Harhash ◽  
Mahmoud Shalash ◽  
Noha Ismael Awad
Keyword(s):  
Bone Density ◽  
Laser Therapy ◽  
Predictor Variable ◽  
Low Level Laser Therapy ◽  
Outcome Variable ◽  
Control Group ◽  
Low Level ◽  
Low Level Laser ◽  
Level Laser ◽  
Significant Difference

AIM: The aim of the study was to evaluate the effect of Low-Level Laser Therapy (LLLT) on bone formation in cystic defects following cyst enucleation.PATIENTS AND METHODS: The sample was composed of sixteen patients with enucleated maxillary bony cystic lesions. With an age range from 20 - 44 grouped as eight Laser and eight Control patients. Laser group was subjected to low intensity diode laser immediately after surgery and then for three times per week for two weeks using a therapeutic laser irradiation. Group B (control group): patients were not subjected laser therapy.RESULTS: The predictor variable was exposure of bone defect to LLLT or none. The outcome variable was bone density changes measured by digital radiographs at day 1 and days 90 postoperatively. Descriptive and bivariate statistics were computed. There were no statistically significant differences between the 2 groups for the bone density at day 1. There was a statistically significant difference in bone density changes in each group at day 90: Significant at P ≤ 0.05. After adjusting for differences in day 1 for bone density, the estimated mean change in bone density changes at day 90 was significantly larger for Laser compared with control.CONCLUSION: The results of this study suggested that LLLT can enhance bone healing in maxillary cystic defects. This can serve as an adjunct method in preventing possible delayed healing and pathological fractures This also will be helpful for more researchers in early loading in case of dental implants to accelerate osseointegration.

scholarly journals Association between the C-reactive protein/albumin ratio and prognosis in patients with oral squamous cell carcinoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kenji Yamagata ◽  
Satoshi Fukuzawa ◽  
Naomi Ishibashi-Kanno ◽  
Fumihiko Uchida ◽  
Hiroki Bukawa
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Prognostic Marker ◽  
Squamous Cell ◽  
Inflammatory Markers ◽  
Outcome Variable ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Significant Difference

AbstractThe systemic inflammatory response is known to be associated with poor outcomes in patients with various types of cancer. The C-reactive protein (CRP)/albumin (Alb) ratio (CAR) has been reported as a novel inflammation-based prognostic marker. We have evaluated the prognostic value of inflammatory markers for patients with oral squamous cell carcinoma (OSCC). The study population included 205 patients treated with OSCC between 2013 and 2018. The primary predictor variable was the inflammatory markers. The primary outcome variable was overall survival (OS). Univariate and multivariate analyses were performed using a Cox proportional hazards model to identify independent prognostic factors. The CAR had the highest area under the curve (AUC) values compared with other markers in the receiver operating characteristic (ROC) curve analysis. The cutoff value for CAR was 0.032 (AUC 0.693, P < 0.001). There was a significant difference in OS when patients were stratified according to CAR, with 79.1% for CAR < 0.032 and 35% for CAR ≥ 0.032 (P < 0.001). Cox multivariate analysis identified independent predictive factors for OS: age (hazard ratio [HR] 2.155, 95% confidence interval [CI] 1.262–3.682; P = 0.005), stage (HR 3.031, 95% CI 1.576–5.827; P = 0.001), and CAR (HR 2.859, 95% CI 1.667–4.904; P < 0.001). CAR (≥ 0.032 vs. < 0.032) is a good prognostic marker in patients with OSCC in terms of age and stage.

scholarly journals Detecting Instruction Effects—Deciding Between Covariance Analytical and Change-Score Approach

2021 ◽  
Author(s):  
Carmen Köhler ◽  
Johannes Hartig ◽  
Alexander Naumann
Keyword(s):  
Latent Variable ◽  
Outcome Measurement ◽  
Predictor Variable ◽  
Change Score ◽  
Regression Coefficients ◽  
Outcome Variable ◽  
Analysis Model ◽  
Hypothetical Data ◽  
Instructional Research ◽  
Time Point

AbstractThe article focuses on estimating effects in nonrandomized studies with two outcome measurement occasions and one predictor variable. Given such a design, the analysis approach can be to include the measurement at the previous time point as a predictor in the regression model (ANCOVA), or to predict the change-score of the outcome variable (CHANGE). Researchers demonstrated that both approaches can result in different conclusions regarding the reported effect. Current recommendations on when to apply which approach are, in part, contradictory. In addition, they lack direct reference to the educational and instructional research contexts, since they do not consider latent variable models in which variables are measured without measurement error. This contribution assists researchers in making decisions regarding their analysis model. Using an underlying hypothetical data-generating model, we identify for which kind of data-generating scenario (i.e., under which assumptions) the defined true effect equals the estimated regression coefficients of the ANCOVA and the CHANGE approach. We give empirical examples from instructional research and discuss which approach is more appropriate, respectively.

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