scholarly journals Comparison of the Technological Application Potential of Functional Ingredients for the Meat Industry Based upon a Novel Fast Screening Tool

Foods ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2078
Author(s):  
Olivier Goemaere ◽  
Bart De Ketelaere ◽  
Jana Hanskens ◽  
Quinten Masijn ◽  
Cristina Pérez Santaescolastica ◽  
...  
Keyword(s):  
Screening Tool ◽  
Binding Capacity ◽  
Model Systems ◽  
Meat Industry ◽  
Comparable Data ◽  
Functional Ingredients ◽  
Fast Screening ◽  
Functional Classes ◽  
Application Potential ◽  
Application Characteristics

The application potential of functional ingredients for the meat industry is often assessed through different measuring tools, thereby making comparisons difficult. The aim of this study was to create valuable information about the performance of functional ingredients based upon standardized and comparable data gathered through a newly developed screening tool. Therefore, 25 ingredients, selected from different techno-functional classes, were characterized at 2 different dosages by means of the screening methodology. The tool itself consisted of a lean meat model and fatty liver-based system, representative of the finely minced and/or emulsified charcuterie market. A total of 23 different parameters were measured through both model systems, providing information concerning water and fat binding capacity, emulsification, and texture and structure formation. Through cluster analysis, the ingredients were assigned to groups, each with their own specific properties. The screening tool provided good descriptive and distinctive power concerning ingredient functionalities and offers the industry a clear overview of their application characteristics.

scholarly journals Private Antibody Repertoires Are Public

2020 ◽  
Author(s):  
Rohit Arora ◽  
Ramy Arnaout
Keyword(s):  
Antibody Response ◽  
Binding Capacity ◽  
Antigen Binding ◽  
Binding Studies ◽  
Considerable Heterogeneity ◽  
Core Set ◽  
Functional Classes ◽  
Repertoire Diversity ◽  
Antibody Repertoires ◽  
The Ideal

When faced with a given pathogen, the antibody response generally functions similarly across different people,1–4 but the source of this similarity has been unclear. One hypothesis was that people share a high proportion of the same VDJ-recombined antibody genes, but this has been disproven.5,6 An alternative is that people share a high proportion of functionally similar antibodies,7,8 but testing this hypothesis requires a method for measuring functional similarity that scales to the millions of antibodies per repertoire and across multiple repertoires, which is impossible experimentally. We recently described a framework for doing so computationally,9 which revealed that repertoires consist of loose overlapping functional classes of antibodies with similar antigen-binding capacities;10–12 this framework allowed us to estimate a repertoire’s antigen-binding capacity, τ, for the ideal target of any given antibody. Here, we show that this framework supports the second hypothesis, and provide the first comprehensive demonstration of overwhelming functional overlap between repertoires from 20 different individuals directly from sequence, without need of binding studies. Overlap is highest among the young and falls with age, due to the selective loss of antibodies that represent a core set of shared or “public” antigen-binding capacities. We reveal considerable heterogeneity in antigen-binding capacities for antibodies against influenza, HIV, and SARS-CoV-2, and show that while some of these classes shrink with age, others persist across individuals. These discoveries change our understanding of repertoire diversity and have implications for vaccine and therapeutic-antibody development, especially for the aged.

scholarly journals Blurring of vision with malaise

2021 ◽  
Vol 51 (1) ◽  
pp. 49-52
Author(s):  
Mansoor Zafar ◽  
◽  
Ratan Randhawa
Keyword(s):  
Screening Tool ◽  
Visual Fields ◽  
Initial Screening ◽  
Initial Examination ◽  
Blurred Vision ◽  
Tertiary Centre ◽  
Fast Screening ◽  
Ambulance Transport ◽  
Speech Time ◽  
Ambulance Crew

We present the case of a 56-year-old female brought to the Emergency Department via routine ambulance transport with complaints of blurred vision and malaise. She was screened by ambulance crew using the facial arm speech time (FAST) tool and a basic top-to-toe assessment as per current routine. The examining practitioner performed a thorough assessment of the patient, revisiting the initial examination findings, and establishing new clinical features of visual field deficit and pan-systolic murmur. The likely diagnosis of septic emboli or stroke with infective endocarditis was identified through the power of rigorous history taking and examination. These were then supported by investigation with blood tests and imaging. This prompted discussion with a tertiary centre and subsequent transfer for further investigation and management. The patient’s journey shows that there may indeed be a role for a more comprehensive (but not exhaustive) initial screening from ambulance services in order to help appropriately stream specific patients to hospital in a timelier manner (to meet the thrombolysis window). This case supports the addition of V (visual fields) to the FAST screening tool.

BET 2: FAST or ROSIER to identify suspected stroke in the prehospital setting?

2020 ◽  
Vol 37 (9) ◽  
pp. 587-588
Author(s):  
Ian Gibbons ◽  
Owen Williams
Keyword(s):  
Patient Group ◽  
Screening Tool ◽  
Prehospital Setting ◽  
Clinical Question ◽  
Fast Screening ◽  
Suspected Stroke ◽  
Study Type

A short cut review was carried out to whether the FAST screening tool is more accurate than the ROSIER tool at correctly identifying those with stroke in the prehospital setting. 9 papers presented the best evidence to answer the clinical question. The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these papers are tabulated. It is concluded that FAST and ROSIER have similar sensitivities in the recognition of stroke, with ROSIER demonstrating a higher specificity in the prehospital setting.

High-performance thin-layer chromatography as a fast screening tool for phosphorylated peptides

2016 ◽  
Vol 1008 ◽  
pp. 198-205 ◽  
Author(s):  
Lena Morschheuser ◽  
Sandra Mükusch ◽  
Maria Riedner ◽  
Harald Seitz ◽  
Sascha Rohn
Keyword(s):  
Thin Layer ◽  
Thin Layer Chromatography ◽  
High Performance ◽  
Screening Tool ◽  
Fast Screening ◽  
Phosphorylated Peptides ◽  
Layer Chromatography

FV 257. Munich Early Recognition of Childhood Stroke—More than a FAST Screening Tool

2018 ◽  
Author(s):  
Michaela Bonfert ◽  
Florian Heinen ◽  
Ingo Borggräfe ◽  
Sebastian Schröder ◽  
Moritz Tacke ◽  
...  
Keyword(s):  
Screening Tool ◽  
Early Recognition ◽  
Childhood Stroke ◽  
Fast Screening

scholarly journals Disassembling the complexity of mucus barriers to develop a fast screening tool for early drug discovery

2019 ◽  
Vol 7 (32) ◽  
pp. 4940-4952 ◽  
Author(s):  
Daniela Peneda Pacheco ◽  
Cosmin Stefan Butnarasu ◽  
Francesco Briatico Vangosa ◽  
Laura Pastorino ◽  
Livia Visai ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Discovery ◽  
Screening Tool ◽  
Protective Role ◽  
Effective Drug ◽  
Drug Diffusion ◽  
Fast Screening ◽  
Target Sites ◽  
Natural Barrier ◽  
Early Drug

Mucus is a natural barrier with a protective role that hinders drug diffusion, representing a steric and interactive barrier to overcome for an effective drug delivery to target sites.

scholarly journals USE OF OILSEED POLYFUNCTIONAL SUPPLEMENTS IN THE MANUFACTURE OF MEAT PRODUCTS

2019 ◽  
Vol 13 (2) ◽  
Author(s):  
O. Topchii ◽  
Ye. Kotliar ◽  
T. Honcharenko ◽  
A. Petryna ◽  
O. Tarasiuk
Keyword(s):  
Nutritional Value ◽  
Raw Materials ◽  
Meat Products ◽  
Quality Parameters ◽  
Model Systems ◽  
Meat Production ◽  
Technological Parameters ◽  
Organoleptic Evaluation ◽  
Functional Ingredients ◽  
Organoleptic Characteristics

Nowadays, meat production is developing towards a wider range of products. Their components are optimised and combined in such a way as to increase the nutritional value, to preserve the most valuable components of raw materials, to make for some lacking macro- and micronutrients by including the functional ingredients in the recipe. A possible way to improve the meat products technology is making purposeful changes in the formulation of the product. This involves selecting certain types of raw materials and additional components in ratios providing the required nutritional value of the finished product. New functional ingredients having the desired physiological effects on the human body should be combined with new, modern means of processing raw materials that will provide the necessary technological characteristics, the quality and safety of the final product. Home-manufactured vegetable supplements obtained from seeds of different crops are a promising direction of research. Their unique chemical composition and functional properties allow achieving the expected nutritional value of the finished product in accordance with modern nutritional standards. This article presents the results of analysing and studying of oilseeds aimed at creating a balanced multifunctional supplement to be used in recipes of functional meat products. It has been studied how the functional and technological parameters of seeds change depending on the degree of their grinding. The organoleptic evaluation has allowed determining the optimum ratio of plant components in the mixture. The quality parameters of the supplement developed, its biological value, vitamin and mineral composition have been determined. The organoleptic characteristics and structural and mechanical parameters of meat model systems have been analysed, which has made it possible to recommend the right percentage of the composite oilseed mixture in the recipes of meat products, namely, pates and chopped semi-finished products.

Sign in / Sign up

Export Citation Format

Share Document