Nuclear Cytoskeleton in Virus Infection

The nuclear lamina is the main component of the nuclear cytoskeleton that maintains the integrity of the nucleus. However, it represents a natural barrier for viruses replicating in the cell nucleus. The lamina blocks viruses from being trafficked to the nucleus for replication, but it also impedes the nuclear egress of the progeny of viral particles. Thus, viruses have evolved mechanisms to overcome this obstacle. Large viruses induce the assembly of multiprotein complexes that are anchored to the inner nuclear membrane. Important components of these complexes are the viral and cellular kinases phosphorylating the lamina and promoting its disaggregation, therefore allowing virus egress. Small viruses also use cellular kinases to induce lamina phosphorylation and the subsequent disruption in order to facilitate the import of viral particles during the early stages of infection or during their nuclear egress. Another component of the nuclear cytoskeleton, nuclear actin, is exploited by viruses for the intranuclear movement of their particles from the replication sites to the nuclear periphery. This study focuses on exploitation of the nuclear cytoskeleton by viruses, although this is just the beginning for many viruses, and promises to reveal the mechanisms and dynamic of physiological and pathological processes in the nucleus.

Molecular Epidemiology of Rabies in Wild Canidae in Tunisia

Rabies is a viral zoonosis that is transmissible to humans via domestic and wild animals. There are two epidemiological cycles for rabies, the urban and the sylvatic cycles. In an attempt to study the epidemiological role of wild canidae in rabies transmission, the present study aimed to analyze the genetic characteristics of virus isolates and confirm prior suggestions that rabies is maintained through a dog reservoir in Tunisia. Virus strains isolated from wild canidae were subject to viral sequencing, and Bayesian phylogenetic analysis was performed using Beast2 software. Essentially, the virus strains isolated from wild canidae belonged to the Africa-1 clade, which clearly diverges from fox-related strains. Our study also demonstrated that genetic characteristics of the virus isolates were not as distinct as could be expected if a wild reservoir had already existed. On the contrary, the geographic landscape is responsible for the genetic diversity of the virus. The landscape itself could have also acted as a natural barrier to the spread of the virus.

Detection of seagrass distribution in Bintan Island using SPOT-7 Satellite Imagery and Unmanned Surface Vehicle (USV)

Seagrass has a very important role as a natural barrier to currents and waves from open water. In addition, it plays a significant role in carbon sequestration and storage. In this study, we used SPOT-7 Satellite to detect seagrass distribution in Bintan Island. Bintan Island has the largest seagrass conservation area in Indonesia. The field survey for data collection used an Unmanned Surface Vehicle (USV). Seagrass area is obtained by classifying several objects in the shallow water by using Maximum Likehood Classification algorithm. The seagrass area in the Bintan Island covered about 142.45 ha in 2018, and from the underwater visual system, it was detected that the type of seagrass that dominates the area is Thallasia hemprichii and Enhalus accroides. Therefore, by combining the SPOT-7 satellite imagery and USV we can detect and quantify the seagrass.

Desert Locust Stopped by Tibetan Highlands during the 2020 Upsurge

Desert locust is an important pest to agriculture. In 2019–2020, a major upsurge originated in the southern Arabian Peninsula and gradually spread to east Africa, then to south-west Asia, as far as Pakistan and India, even reaching Nepal, resulting in major agricultural losses. For the first time, a few swarms entered southern Tibet. Using field observations and experiments, we studied their path to the Tibetan plateau and their behavior at these very high altitudes. The locusts moved up the Tibetan valleys from low-lying areas (1700 m) to much higher elevations (5400 m). The low temperatures and high humidity put them under severe stress; their activities were limited, and they did not survive long or produce local offspring. It is clear that the high-altitude environmental conditions in the Himalayan mountains provided an important natural barrier that limited the northward expansion of the desert locust populations.

The impact of mangrove damage on tidal flooding in the subdistrict of Tugu, Semarang, Central Java

Expansion of industrial areas, aquaculture, settlements, and limited knowledge of the community about the function of mangroves allegedly led to the conversion of mangrove functions in the early 1990s. This study aimed to map the condition of mangroves from 1988, 1990, 1995, 2008, to 2021 and their effect on the widespread of tidal flooding in three villages (Mangkang Kulon, Mangunharjo, Mangkang Wetan) in Tugu subdistrict, Semarang City. The research method was carried out by using spatiotemporal analysis of Landsat 5 and Landsat 8 imagery through the supervised approach (Maximum Likelihood algorithm). In order to map the correlation of mangrove damage with the widespread impact of tidal flooding, an overlay analysis of land use maps was carried out in 1988, 1990, 1995, 2008 and 2021. The results of the study showed that mangrove damage is correlated with the widespread of tidal flooding that drowns settlements, ponds, and agricultural land. Data analysis showed that the mangrove area in three villages has decreased from 1988 to 2021, covering an area of 242.66 ha. This condition is one of the triggers for the increase in tidal flooding area from 1988 to 2021, covering an area of 253.135 ha. As a natural barrier to prevent abrasion and tidal flooding, mangrove conservation is very necessary, considering the impact of tidal flooding on the coast of Semarang City is increasingly widespread.

Intralenticular metallic foreign body ‘locked-in’ the posterior capsule and the utility of multimodal imaging

Intraocular foreign bodies (FBs) are common ocular injuries reporting to the emergency services all over the world. The authors highlight the findings and surgical management of a case of intralenticular metallic FB following an injury while using chisel and hammer. The ocular path of the FB (2 mm) could be traced from a self-sealed corneal perforation, extending through the anterior capsule rupture, terminating at the posterior capsule, forming a posterior capsule tent with a part embedded in clear lens. Preoperative ultrasound biomicroscopy gave clues on posterior capsule integrity and the exact site of FB, and helped prognosticate and plan the surgical management of the case. The ‘locked-in’ FB was extracted after clear lens aspiration and posterior capsulorrhexis. The posterior capsule acted as a natural barrier between anterior and posterior segment, where the FB was found embedded.

Naturalization and spread of the alien species Ozognathus cornutus (LeConte, 1859) (Coleoptera: Ptinidae: Ernobiinae) in Italy

Ozognathus cornutus (LeConte, 1859) (Coleoptera: Ptinidae: Ernobiinae), species native to North America, is a saproxylophagous species and is known to feed on decaying tissues within conspicuous galls and on vegetal decaying organic material such as dried fruits or small wood shavings and insect excrements in galleries made by other woodboring species. A few years after the first record in 2011, its naturalization in Italy is here reported. The insect was found as successor in galls of Psectrosema tamaricis (Diptera Cecidomyiidae), Plagiotrochus gallaeramulorum, Andricus multiplicatus and Synophrus politus (Hymenoptera Cynipidae). The galls seem to have played an important ecological role in speeding up the naturalization process. The lowest proportion of galls used by O. cornutus was recorded for P. tamaricis (23%), the only host belonging to Cecidomyiidae, while the percentages recorded for the other host species, all Cynipidae forming galls on oaks, were higher: 43.6%, 61.1% and 76.9% in A multiplicatus, S. politus and P. gallaeramulorum, respectively. Although O. cornutus is able to exploit other substrates like dried fruits and vegetables, for which it could represent a potential pest, it prefers to live as a successor in woody and conspicuous galls, which thus can represent a sort of natural barrier limiting the possible damages to other substrates.

Vulnerability Analysis of the Riumar Dune Field in El Garxal Coastal Wetland (Ebro Delta, Spain)

The aim of this work is to apply a vulnerability index in the dune field located in the Riumar urban zone at the mouth of the Ebro River. This dune field represents the natural barrier of the El Garxal coastal lagoon system. The index used integrates the dimensions of exposure, susceptibility, and resilience from the analysis of 19 variables. The results obtained show moderate susceptibility and high resilience, which are in line with the behavior of this dune field during the last sea storms (Gloria in January 2020 and Philomena in January 2021, among others) that have tested the capacity of this system to cope with the effects of these storms. Therefore, increasing the knowledge of the factors affecting the vulnerability of the dunes can be helpful in the management and conservation of these coastal environments.

Pengendalian Kebisingan Dari Aktivitas Penerbangan di Lingkungan Sekitar Bandara Sultan Thaha Jambi dengan Pemanfaatan Ruang Terbuka Hijau

Noise is a sound pollution and its existence is undesirable in a certain level and time, which has the potential to cause human health problems and environmental comfort. One of the causes of noise levels is due to airport operational activities, from landing to take off. For this reason, it is necessary to control the noise around the Sultan Thaha Jambi airport area, by utilizing green open space as a barrier that can reduce noise levels. This study aims to determine the level of airport noise in certain zones and evaluate the existence of green open space (RTH) whether it is appropriate to become a natural barrier as a barrier to reduce noise caused by flight activities from Sultan Thaha Jambi airport. The results showed the noise level dB (A) from flight activities in each zone, namely the lowest in zones 1 and 3, amounting to 52.08 dB (A), and the highest in zone 5 at 87.93 dB (A). , while the existence of Green Open Space (RTH) is only in zone 1, and 3 are forest park areas, and fields around the Sultan Thaha Jambi airport area, so the existence of this Green Open Space (RTH) is able to reduce noise levels by 2.11 dB (A) based on KEP-48 / MNLH / 11/1996 the quality standard of the allowable noise level is 50 dB (A). While zone 5 is a residential area, the noise level figure is quite high, namely 87.93 dB (A), due to the densely populated area, lack of green open space (RTH), and proximity to motorized vehicle transportation activities, and adjacent to the runway. runway airport. However, not all activities are carried out continuously. So that the residential area is still feasible if exposed to noise exposure either from airport activities or other activities.