scholarly journals Development of Polypyrrole Modified Screen-Printed Carbon Electrode Based Sensors for Determination of L-Tyrosine in Pharmaceutical Products

2021 ◽  
Vol 22 (14) ◽  
pp. 7528
Author(s):  
Ancuța Dinu ◽  
Constantin Apetrei

Good health, of vital importance in order to carry out our daily routine, consists of both physical and mental health. Tyrosine (Tyr) deficiency as well as its excess are issues that can affect mental health and can generate disorders such as depression, anxiety, or stress. Tyr is the amino acid (AA) responsible for maintaining good mental health, and for this reason, the present research presents the development of new electrochemical sensors modified with polypyrrole (PPy) doped with different doping agents such as potassium hexacyanoferrate (II) (FeCN), sodium nitroprusside (NP), and sodium dodecyl sulfate (SDS) for a selective and sensitive detection of Tyr. The development of the sensors was carried out by chronoamperometry (CA) and the electrochemical characterization was carried out by cyclic voltammetry (CV). The detection limits (LOD) obtained with each modified sensor were 8.2 × 10−8 M in the case of PPy /FeCN-SPCE, 4.3 × 10−7 M in the case of PPy/NP-SPCE, and of 3.51 × 10−7 M in the case of PPy/SDS-SPCE, thus demonstrating a good sensitivity of these sensors detecting L-Tyr. The validation of sensors was carried out through quantification of L-Tyr from three pharmaceutical products by the standard addition method with recoveries in the range 99.92–103.97%. Thus, the sensors present adequate selectivity and can be used in the pharmaceutical and medical fields.

Author(s):  
Danny Sheath ◽  
Antoine Flahault ◽  
Joachim Seybold ◽  
Luciano Saso

Forced migration is likely to continue to grow in the coming years due to climate change, disease outbreaks, conflict, and other factors. There are a huge number of challenges to maintaining good health, and specifically good mental health, among migrants at all stages of migration. It is vital to fully understand these diverse challenges so that we can work towards overcoming them. In 2017, as a response to the growing health challenges faced by migrants and refugees, the M8 Alliance created an expert group focussing on migrant and refugee health. The group meets annually at the Sapienza University of Rome, Italy, and this article is based on the discussions that took place at the third annual meeting (6–7 June 2019) and a special session on “Protecting the Mental Health of Refugees and Migrants,” which took place on 27 October at the World Health Summit 2019 in Berlin. Our discussions are also supported by supplementary literature to present the diverse and complex challenges to the mental health of migrants and refugees. We conclude with some lessons learned and hope for the future.


2021 ◽  
Vol 7 (4) ◽  
pp. 1-4
Author(s):  
Gary Null ◽  

A 60-day observational study was conducted to evaluate how lifestyle modification principles relying upon a customized regimen of aerobic and muscle strength exercise, a plant-based diet and meditative stress reduction techniques may improve physical endurance and strength, mental health, and reverse normal aging associated with the average American lifestyle. All enrolled participants were generally in good health respective to their age. Several subjects had overlapping mild medical conditions. The results demonstrate that the intervention of a customized lifestyle modification regimen of regular daily exercise, a plant-based diet, and daily stress reduction practices, such as meditation and yoga, may provide a viable and beneficial preventative strategy as an anti-aging and wellness model to increase the physical and mental health of elderly men and women.


Paragrana ◽  
2013 ◽  
Vol 22 (1) ◽  
pp. 154-164
Author(s):  
Susanne Klien

Abstract This ethnographic study explores bullfighting in Oki and its many functions in contemporary life. It examines how mostly elderly bullfighters differ from other Japanese of their age and how they manage to lead their lives to the fullest, maintaining a high level of physical and mental health. With depictions of both the daily routine and bullfighting events, the paper enquires into the meaning of bullfighting and its related activities for actors involved in it, how bullfighters learn social skills in the stables and the arena, and how bullfighting creates well-being both on an individual and collective level. The hypothesis is that the sense of satisfaction of bullfighters accrues from a balance of activities as discrete individual and social interaction, communication, and intergenerational exchange.


2021 ◽  
Vol 12 ◽  
Author(s):  
Raghuram Nagarathna ◽  
Akshay Anand ◽  
Manjari Rain ◽  
Vinod Srivastava ◽  
Madhava Sai Sivapuram ◽  
...  

Uncertainty about Coronavirus disease 2019 (COVID-19) and resulting lockdown caused widespread panic, stress, and anxiety. Yoga is a known practice that reduces stress and anxiety and may enhance immunity. This study aimed to (1) investigate that including Yoga in daily routine is beneficial for physical and mental health, and (2) to evaluate lifestyle of Yoga practitioners that may be instrumental in coping with stress associated with lockdown. This is a pan-India cross-sectional survey study, which was conducted during the lockdown. A self-rated scale, COVID Health Assessment Scale (CHAS), was designed by 11 experts in 3 Delphi rounds (Content valid ratio = 0.85) to evaluate the physical health, mental health, lifestyle, and coping skills of the individuals. The survey was made available digitally using Google forms and collected 23,760 CHAS responses. There were 23,290 valid responses (98%). After the study's inclusion and exclusion criteria of yogic practices, the respondents were categorized into the Yoga (n = 9,840) and Non-Yoga (n = 3,377) groups, who actively practiced Yoga during the lockdown in India. The statistical analyses were performed running logistic and multinomial regression and calculating odds ratio estimation using R software version 4.0.0. The non-Yoga group was more likely to use substances and unhealthy food and less likely to have good quality sleep. Yoga practitioners reported good physical ability and endurance. Yoga group also showed less anxiety, stress, fear, and having better coping strategies than the non-Yoga group. The Yoga group displayed striking and superior ability to cope with stress and anxiety associated with lockdown and COVID-19. In the Yoga group, participants performing meditation reportedly had relatively better mental health. Yoga may lead to risk reduction of COVID-19 by decreasing stress and improving immunity if specific yoga protocols are implemented through a global public health initiative.


Author(s):  
Gilberto Campos Guimarães Filho ◽  
Maria Emília Figueiredo Teixeira ◽  
Idiberto José Zotarelli Filho ◽  
Patrícia Maluf Cury ◽  
Giancarlo Lucchetti

The new coronavirus (SARS-CoV-2), whose disease is COVID-19, in March 2020, spread around the world. To minimize the deleterious effects of emotional vulnerability, many strategies are in use worldwide, such as support groups, online courses, use of social networks, web meetings, yoga practice, meditation, and other contemplative religious and spiritual activities. Religious and spiritual beliefs have been used to deal with tough situations and, through scientific literature is still not so clear about the role of spirituality and religiosity (S/R) in physical and mental health during the pandemic. Therefore, this article proposes a discussion about the physiopathological mechanisms of COVID-19 and how S/R could be useful in this context. In this sense, religious faith can be a powerful resource for good health and well-being with a positive impact verified in mental health outcomes it is plausible to suggest that S/R should be an important tool in minimizing the population suffering at this moment. Spiritual care has long been recognized as one of the domains of quality palliative care, but every health care professional is ultimately responsible for ensuring spiritual care to deal with spiritual distress and improve quality of life in the scenarios inherent to COVID-19.


Author(s):  
Altaf Saadi ◽  
Caitlin Patler ◽  
Maria-Elena De Trinidad Young

Abstract Objectives The USA maintains the world’s largest immigration detention system. This study examines the mechanisms by which detention serves as a catalyst for worsening health. Methods Using data from detained immigrants in California (n = 493) from 2013 to 2014, we assessed the prevalence of exposure to conditions of confinement hypothesized to negatively influence health; the extent to which conditions of confinement are associated with psychological stress, diagnosed mental health conditions, and/or declines in general health; and the cumulative impact of confinement conditions on these outcomes. Results We found that each condition increased the likelihood of one or more negative health conditions, but there was also a cumulative effect: for each additional confinement condition, the odds of worsening general health rose by 39% and reporting good health decreased by 24%. Conclusions Confinement conditions are associated with poor physical and mental health outcomes among immigrants detained in immigration prisons. Policies that seek to improve specific conditions in detention centers may remove some risks of harm, but alternatives to detention are likely to be most effective.


Author(s):  
Dr. Shanti Chauhan ◽  
Dr. Sheela Halli ◽  
Dr.Komal Pawar ◽  
Dr. Ishwari Patil ◽  
Dr. Rashmi Hadimani

Purpose: As the good nutritional food provides physical health, the unborn child in the womb require Sanskara to acquire mental health to thrive. The activity of mother during pregnancy in the form of prayer (good rational thoughts), Manshakti (positive emotion), conversation with fetus (talk) or expressing feeling (touch) is not only recognised by unborn baby but it has a positive effects on physical and mental health. Hence, Garbhasanskara is scientific way of moulding mental health of unborn child. Method: Ayurveda classics, textbook of obstetrics and internet publications were consulted and reviewed for carrying out the present work. Result: The sanskrit word 'Garbha' means fetus in the womb and Sanskara means educating the mind. So, Garbhasanskara essentially means educating the mind of the fetus. The fundamental principle underlying Garbhasanskara is that unborn baby is able to sense, feel, listen, dream, respond to outside stimulus. Even, Ancient Indian medicine has recognized the need for the mental, spiritual and physical preparation of mother-to-be for the momentous event of childbirth. Ayurveda describes this theory as "Supraja Janan" or eu-maternity. This "Supraja Janan" involves the preparation of couple planning pregnancy, 3 months prior to conception. It can be achieved by regular practice of Garbhasanskara which includes music therapy, Mantra therapy, proper Ahara and Vihara, Yoga and meditation. To develop the desired qualities in the baby every mother should follow the process of Garbhasanskara. Discussion: Garbhasanskara is a process of nurturing the baby in womb. It is also process of training the baby as well as mothers mind during pregnancy. It helps in positive state of mind throughout pregnancy, enhances chances of normal delivery, good health of mother during pre and post conception upto delivery and pregnancy occurs without any complication which is the need of current situation due to unhealthy lifestyle habits. So, a broad expanse of this is described in the present paper.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S319-S319
Author(s):  
Samuel Asante ◽  
Eun-Jun Bang

Abstract Social support is fundamental to human survival, and is significantly involved in the attainment and maintenance of good health and wellbeing. Previous studies have often considered social support as a singular, non-dimensional construct. While this is important and enlightening, the method of adding up individual aspects to create a singular, non-dimensional construct has produced little understanding of these aspects/dimensions of social support and their implications for health. This study examined three dimensions or types of social support-affective, confidant, and instrumental support-and their associations with physical and mental health in older adults. Data for this study were obtain from Utah Fertility, Longevity, and Aging (FLAG) study. Participants involved 325 older adults, aged 50 years or older. Results showed a significant, strong positive correlation between affective support and physical and mental health, and weak association between confidant support and physical and mental health. The correlation between instrumental support and physical and mental health was moderate. After controlling for the influence of socio-demographic variables, affective and instrumental support significantly predicted physical and mental health. Confidant support was not a significant predictor of either physical or mental health. The findings suggest both affective and instrumental support might be relatively more important to the health and mental wellbeing of older adults than confidant support, underscoring the relative importance older adults attach to quality rather than confidant support, which essentially is quantity of social ties.


Revista Labor ◽  
2018 ◽  
Vol 1 (19) ◽  
pp. 75
Author(s):  
Geyse Chrystine Pereira Souza Fernandes ◽  
Luc Vandenbergue

As condições estressantes enfrentadas na rotina diária do professor podem levar a um desequilíbrio entre o trabalho e a saúde física e mental, resultando no desenvolvimento do estresse, como a Síndrome de Burnout - SB. Diante disso, este estudo buscou, na literatura, quais as relações entre estresse e trabalho docente. O presente estudo trata-se de uma revisão do tipo integrativa. Os resultados apontaram vários assuntos em torno do estresse. Assim formaram-se duas categorias que abrangem A Síndrome de Bournout e Outros Transtornos. Os resultados apontam que o excesso de atividades e o desgaste emocional a que os docentes estão sujeitos no trabalho os tornam mais susceptíveis e vulneráveis ao desenvolvimento de transtornos relacionados ao estresse. ABSTRACTThe stressful conditions faced in the teacher's daily routine can lead to an imbalance between work and physical and mental health, resulting in the development of stress, like Burnout Syndrome - SB. Therefore, this study sought, in the literature, the relations between stress and teaching work. The present study is about a review of the integrative type. The results pointed to several issues around stress. Thus two categories were formed covering Bournout Syndrome and Other Disorders. The results indicate that the excess of activities and the emotional exhaustion that the teachers are subject to at work make them more susceptible and vulnerable to the development of stress-related disorders. KEY WORDS: stress - teacher work - teacher.


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250341
Author(s):  
Brigitte Voisard ◽  
Rob Whitley ◽  
Eric Latimer ◽  
Karl Looper ◽  
Vincent Laliberté

PRISM (Projet Réaffiliation Itinérance Santé Mentale–mental health and homelessness reaffiliation project), is a new shelter-based mental health service in Montreal, Canada. It offers short-term residential services in a shelter with the aim of housing and connecting the person to the appropriate services in the community. This qualitative research project was designed to gain a rich understanding of service-user experience within this program, and to apply these impressions to a broader reflection concerning how to best serve the needs of homeless people living with severe mental illness. We conducted in-depth interviews with 20 clients from the all-male PRISM-Welcome Hall Mission at program intake and departure between May 2018 and March 2019. We used methods stemming from grounded theory to analyze themes emerging from the interviews. Analysis revealed three core aspects endorsed by PRISM clients as helpful to their recovery: first, the community-based and flexible PRISM structure allows for continuity in daily routine through the preservation and expansion of the client’s existing informal resource network; second, the secure environment is conducive to improving one’s physical and mental health; and third, the multimodal mental health and social service approach used at PRISM is appreciated and stands in contrast to what most have experienced during other inpatient experiences. This led us to reflect more broadly on the benefits of a shelter-based intervention, as a catalyst to the achievement of longer-term goals such as housing, as well as flexible care adapted to the specific needs of these individuals. Even though this study took place in a specific program in Quebec, it sheds light more broadly on how to best meet the needs of individuals with mental illness living in homeless situations and contributes to the growing literature on men’s mental health.


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