scholarly journals Responses to Developmental Temperature Fluctuation in Life History Traits of Five Drosophila Species (Diptera: Drosophilidae) from Different Thermal Niches

Insects ◽  
2021 ◽  
Vol 12 (10) ◽  
pp. 925
Author(s):  
Tommaso Manenti ◽  
Anders Kjærsgaard ◽  
Toke Munk Schou ◽  
Cino Pertoldi ◽  
Neda N. Moghadam ◽  
...  
Keyword(s):  
Thermal Resistance ◽  
Temperature Fluctuation ◽  
Developmental Time ◽  
Drosophila Species ◽  
Model Organisms ◽  
Wing Size ◽  
Multiple Traits ◽  
Biochemical Processes ◽  
Developmental Temperature ◽  
The Impact

Temperature has profound effects on biochemical processes as suggested by the extensive variation in performance of organisms across temperatures. Nonetheless, the use of fluctuating temperature (FT) regimes in laboratory experiments compared to constant temperature (CT) regimes is still mainly applied in studies of model organisms. We investigated how two amplitudes of developmental temperature fluctuation (22.5/27.5 °C and 20/30 °C, 12/12 h) affected several fitness-related traits in five Drosophila species with markedly different thermal resistance. Egg-to-adult viability did not change much with temperature except in the cold-adapted D. immigrans. Developmental time increased with FT among all species compared to the same mean CT. The impact of FT on wing size was quite diverse among species. Whereas wing size decreased quasi-linearly with CT in all species, there were large qualitative differences with FT. Changes in wing aspect ratio due to FT were large compared to the other traits and presumably a consequence of thermal stress. These results demonstrate that species of the same genus but with different thermal resistance can show substantial differences in responses to fluctuating developmental temperatures not predictable by constant developmental temperatures. Testing multiple traits facilitated the interpretation of responses to FT in a broader context.

scholarly journals Fire Resistance Behaviour of Geopolymer Concrete:An Overview

Buildings ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 82
Author(s):  
Salmabanu Luhar ◽  
Demetris Nicolaides ◽  
Ismail Luhar
Keyword(s):  
Compressive Strength ◽  
Thermal Resistance ◽  
Building Materials ◽  
Elevated Temperatures ◽  
Construction Materials ◽  
Flexural Behavior ◽  
Thermal Shrinkage ◽  
Physico Chemical ◽  
The Impact ◽  
Loss Of Strength

Even though, an innovative inorganic family of geopolymer concretes are eye-catching potential building materials, it is quite essential to comprehend the fire and thermal resistance of these structural materials at a very high temperature and also when experiencing fire with a view to make certain not only the safety and security of lives and properties but also to establish them as more sustainable edifice materials for future. The experimental and field observations of degree of cracking, spalling and loss of strength within the geopolymer concretes subsequent to exposure at elevated temperature and incidences of occurrences of disastrous fires extend an indication of their resistance against such severely catastrophic conditions. The impact of heat and fire on mechanical attributes viz., mechanical-compressive strength, flexural behavior, elastic modulus; durability—thermal shrinkage; chemical stability; the impact of thermal creep on compressive strength; and microstructure properties—XRD, FTIR, NMR, SEM as well as physico-chemical modifications of geopolymer composites subsequent to their exposures at elevated temperatures is reviewed in depth. The present scientific state-of-the-art review manuscript aimed to assess the fire and thermal resistance of geopolymer concrete along with its thermo-chemistry at a towering temperature in order to introduce this novel, most modern, user and eco-benign construction materials as potentially promising, sustainable, durable, thermal and fire-resistant building materials promoting their optimal and apposite applications for construction and infrastructure industries.

scholarly journals Developmental up-regulation of NMDA receptors in the prefrontal cortex and hippocampus of mGlu5 receptor knock-out mice

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Tiziana Imbriglio ◽  
Remy Verhaeghe ◽  
Nico Antenucci ◽  
Stefania Maccari ◽  
Giuseppe Battaglia ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Nmda Receptor ◽  
Metabotropic Glutamate Receptors ◽  
Adult Life ◽  
Developmental Time ◽  
Postnatal Life ◽  
Developmental Studies ◽  
Knock Out ◽  
Nmda Receptor Subunits ◽  
The Impact

AbstractmGlu5 metabotropic glutamate receptors are highly expressed and functional in the early postnatal life, and are known to positively modulate NMDA receptor function. Here, we examined the expression of NMDA receptor subunits and interneuron-related genes in the prefrontal cortex and hippocampus of mGlu5−/− mice and wild-type littermates at three developmental time points (PND9, − 21, and − 75). We were surprised to find that expression of all NMDA receptor subunits was greatly enhanced in mGlu5−/− mice at PND21. In contrast, at PND9, expression of the GluN2B subunit was enhanced, whereas expression of GluN2A and GluN2D subunits was reduced in both regions. These modifications were transient and disappeared in the adult life (PND75). Changes in the transcripts of interneuron-related genes (encoding parvalbumin, somatostatin, vasoactive intestinal peptide, reelin, and the two isoforms of glutamate decarboxylase) were also observed in mGlu5−/− mice across postnatal development. For example, the transcript encoding parvalbumin was up-regulated in the prefrontal cortex of mGlu5−/− mice at PND9 and PND21, whereas it was significantly reduced at PND75. These findings suggest that in mGlu5−/− mice a transient overexpression of NMDA receptor subunits may compensate for the lack of the NMDA receptor partner, mGlu5. Interestingly, in mGlu5−/− mice the behavioral response to the NMDA channel blocker, MK-801, was significantly increased at PND21, and largely reduced at PND75. The impact of adaptive changes in the expression of NMDA receptor subunits should be taken into account when mGlu5−/− mice are used for developmental studies.

scholarly journals Ozone damage, detoxification and the role of isoprenoids – new impetus for integrated models

2016 ◽  
Vol 43 (4) ◽  
pp. 324 ◽  
Author(s):  
Supriya Tiwari ◽  
Rüdiger Grote ◽  
Galina Churkina ◽  
Tim Butler
Keyword(s):  
Stomatal Conductance ◽  
Environmental Conditions ◽  
Economic Losses ◽  
Plant Responses ◽  
Damage Scenarios ◽  
Biochemical Processes ◽  
Wide Range ◽  
Defence Responses ◽  
High Concentrations ◽  
The Impact

High concentrations of ozone (O3) can have significant impacts on the health and productivity of agricultural and forest ecosystems, leading to significant economic losses. In order to estimate this impact under a wide range of environmental conditions, the mechanisms of O3 impacts on physiological and biochemical processes have been intensively investigated. This includes the impact on stomatal conductance, the formation of reactive oxygen species and their effects on enzymes and membranes, as well as several induced and constitutive defence responses. This review summarises these processes, discusses their importance for O3 damage scenarios and assesses to which degree this knowledge is currently used in ecosystem models which are applied for impact analyses. We found that even in highly sophisticated models, feedbacks affecting regulation, detoxification capacity and vulnerability are generally not considered. This implies that O3 inflicted alterations in carbon and water balances cannot be sufficiently well described to cover immediate plant responses under changing environmental conditions. Therefore, we suggest conceptual models that link the depicted feedbacks to available process-based descriptions of stomatal conductance, photosynthesis and isoprenoid formation, particularly the linkage to isoprenoid models opens up new options for describing biosphere-atmosphere interactions.

On the stability of a mathematical model for HIV(AIDS) - cancer dynamics

2021 ◽  
Vol 8 (4) ◽  
pp. 783-796
Author(s):  
H. W. Salih ◽  
◽  
A. Nachaoui ◽  
Keyword(s):  
Mathematical Model ◽  
Highly Active Antiretroviral Therapy ◽  
Lyapunov Method ◽  
Equilibrium Points ◽  
Hiv Treatment ◽  
Biochemical Processes ◽  
Highly Active ◽  
Biological Phenomena ◽  
The Stability ◽  
The Impact

In this work, we study an impulsive mathematical model proposed by Chavez et al. [1] to describe the dynamics of cancer growth and HIV infection, when chemotherapy and HIV treatment are combined. To better understand these complex biological phenomena, we study the stability of equilibrium points. To do this, we construct an appropriate Lyapunov function for the first equilibrium point while the indirect Lyapunov method is used for the second one. None of the equilibrium points obtained allow us to study the stability of the chemotherapeutic dynamics, we then propose a bifurcation of the model and make a study of the bifurcated system which contributes to a better understanding of the underlying biochemical processes which govern this highly active antiretroviral therapy. This shows that this mathematical model is sufficiently realistic to formulate the impact of this treatment.

scholarly journals Rapture-ready darters: choice of reference genome and genotyping method (whole-genome or sequence capture) influence population genomic inference in Etheostoma

2020 ◽  
Author(s):  
Brendan N. Reid ◽  
Rachel L. Moran ◽  
Christopher J. Kopack ◽  
Sarah W. Fitzpatrick
Keyword(s):  
Reference Genome ◽  
Sequence Data ◽  
Low Cost ◽  
Read Depth ◽  
Model Organisms ◽  
Whole Genome ◽  
Reduced Representation ◽  
Sequence Capture ◽  
Population Genomic ◽  
The Impact

AbstractResearchers studying non-model organisms have an increasing number of methods available for generating genomic data. However, the applicability of different methods across species, as well as the effect of reference genome choice on population genomic inference, are still difficult to predict in many cases. We evaluated the impact of data type (whole-genome vs. reduced representation) and reference genome choice on data quality and on population genomic and phylogenomic inference across several species of darters (subfamily Etheostomatinae), a highly diverse radiation of freshwater fish. We generated a high-quality reference genome and developed a hybrid RADseq/sequence capture (Rapture) protocol for the Arkansas darter (Etheostoma cragini). Rapture data from 1900 individuals spanning four darter species showed recovery of most loci across darter species at high depth and consistent estimates of heterozygosity regardless of reference genome choice. Loci with baits spanning both sides of the restriction enzyme cut site performed especially well across species. For low-coverage whole-genome data, choice of reference genome affected read depth and inferred heterozygosity. For similar amounts of sequence data, Rapture performed better at identifying fine-scale genetic structure compared to whole-genome sequencing. Rapture loci also recovered an accurate phylogeny for the study species and demonstrated high phylogenetic informativeness across the evolutionary history of the genus Etheostoma. Low cost and high cross-species effectiveness regardless of reference genome suggest that Rapture and similar sequence capture methods may be worthwhile choices for studies of diverse species radiations.

Understanding the Impact of Flow Bypass on the Thermal Performance of Air Cooled Heat Sinks

2014 ◽  
Author(s):  
Krishna Kota ◽  
Mohamed M. Awad
Keyword(s):  
Energy Conservation ◽  
Thermal Resistance ◽  
Thermal Performance ◽  
Heat Sink ◽  
Heat Sinks ◽  
Laminar Regime ◽  
Flow Energy ◽  
Factor Α ◽  
The Impact ◽  
Fundamental Mass

In this effort, theoretical modeling was employed to understand the impact of flow bypass on the thermal performance of air cooled heat sinks. Fundamental mass and flow energy conservation equations across a longitudinal fin heat sink configuration and the bypass region were applied and a generic parameter, referred as the Flow Bypass Factor (α), was identified from the theoretical solution that mathematically captures the effect of flow bypass as a quantifiable parameter on the junction-to-ambient thermal resistance of the heat sink. From the results obtained, it was found that, at least in the laminar regime, the impact of flow bypass on performance can be neglected for cases when the bypass gap is typically less than 5% of the fin height, and is almost linear at high relative bypass gaps (i.e., usually for bypass gaps that are more than 10–15% of the fin height). It was also found that the heat sink thermal resistance is more sensitive to small bypass gaps and the effect of flow bypass decreases with increasing bypass gap.

Improved Heat Dissipation and Optical Performance of High-power LED Packaging with Sintered Nanosilver Die-attach Material

2010 ◽  
Vol 2010 (DPC) ◽  
pp. 001585-001605 ◽  
Author(s):  
Paul Panaccione ◽  
Tao Wang ◽  
Guo-Quan Lu ◽  
Xu Chen ◽  
Susan Luo
Keyword(s):  
Thermal Resistance ◽  
High Power ◽  
Heat Removal ◽  
High Current ◽  
Die Attach ◽  
High Power Led ◽  
Silver Epoxy ◽  
The Difference ◽  
Nanosilver Paste ◽  
The Impact

Heat removal in packaged high-power light-emitting diode (LED) chips is critical to device performance and reliability. Thermal performance of LEDs is important in that lowered junction temperatures extend the LED's lifetime at a given photometric flux (brightness). Optionally, lower thermal resistance can enable increased brightness operation without exceeding the maximum allowable Tj for a given lifetime. A significant portion of the junction-to-case thermal resistance comes from the joint between chip and substrate, or the die-attach layer. In this study, we evaluated three different types of leading die-attach materials; silver epoxy, lead-free solder, and an emerging nanosilver paste. Each of the three was processed via their respective physical and chemical mechanisms: epoxy curing by cross-linking of polymer molecules; intermetalic soldering by reflow and solidification; and nanosilver sintering by solid-state atomic diffusion. High-power LED chips with a chip area of 3.9 mm2 were attached by the three types of materials onto metalized aluminum nitride substrates, wire-bonded, and then tested in an electro-optical setup. The junction-to-heatsink thermal resistance of each LED assembly was determined by the wavelength shift methodology, described in detail in this paper. We found that the average thermal resistance in the chips attached by the nanosilver paste was the lowest, and it is the highest from the chips attached by the silver epoxy: the difference between the two was about 0.7°C/W, while the difference between the sintered and soldered was about 0.3°C/W. The lower thermal resistance in the sintered joints is expected to significantly improve the photometric flux from the device. Simple calculations, excluding high current efficiency droop, predict that the brightness improvement could be as high as 50% for the 3.9 mm2 chip. The samples will be functionally tested at high current, in both steady-state and pulsed operation, to determine brightness improvements, including the impact of droop. Nanosilver die-attach on a range of chip sizes up to 12 mm2 are also considered and discussed.

scholarly journals Effects of the Circuit Arrangement on the Thermal Performance of Double U-Tube Ground Heat Exchangers

Energies ◽  
2020 ◽  
Vol 13 (12) ◽  
pp. 3275
Author(s):  
Aminhossein Jahanbin ◽  
Giovanni Semprini ◽  
Andrea Natale Impiombato ◽  
Cesare Biserni ◽  
Eugenia Rossi di Schio
Keyword(s):  
Thermal Resistance ◽  
Thermal Performance ◽  
Numerical Code ◽  
Geometrical Parameters ◽  
Fluid Temperature ◽  
The Finite Element Method ◽  
Ground Heat Exchangers ◽  
Borehole Thermal Resistance ◽  
The Impact ◽  
Circuit Configuration

Given that the issue of variations in geometrical parameters of the borehole heat exchanger (BHE) revolves around the phenomenon of thermal resistance, a thorough understanding of these parameters is beneficial in enhancing thermal performance of BHEs. The present study seeks to identify relative changes in the thermal performance of double U-tube BHEs triggered by alterations in circuit arrangements, as well as the shank spacing and the borehole length. The thermal performance of double U-tube BHEs with different configurations is comprehensively analyzed through a 3D transient numerical code developed by means of the finite element method. The sensitivity of each circuit configuration in terms of the thermal performance to variations of the borehole length and shank spacing is investigated. The impact of the thermal interference between flowing legs, namely thermal short-circuiting, on parameters affecting the borehole thermal resistance is addressed. Furthermore, the energy exchange characteristics for different circuit configurations are quantified by introducing the thermal effectiveness coefficient. The results indicate that the borehole length is more influential than shank spacing in increasing the discrepancy between thermal performances of different circuit configurations. It is shown that deviation of the averaged-over-the-depth mean fluid temperature from the arithmetic mean of the inlet and outlet temperatures is more critical for lower shank spacings and higher borehole lengths.

scholarly journals A Compass To Boost Navigation: Cell Biology of Bacterial Magnetotaxis

2020 ◽  
Vol 202 (21) ◽  
Author(s):  
Frank D. Müller ◽  
Dirk Schüler ◽  
Daniel Pfeiffer
Keyword(s):  
Magnetic Field ◽  
Cell Biology ◽  
Molecular Mechanisms ◽  
Magnetotactic Bacteria ◽  
Genetically Engineered ◽  
Model Organisms ◽  
Complex Cell ◽  
Magnetite Biomineralization ◽  
Directed Motility ◽  
The Impact

ABSTRACT Magnetotactic bacteria are aquatic or sediment-dwelling microorganisms able to take advantage of the Earth’s magnetic field for directed motility. The source of this amazing trait is magnetosomes, unique organelles used to synthesize single nanometer-sized crystals of magnetic iron minerals that are queued up to build an intracellular compass. Most of these microorganisms cannot be cultivated under controlled conditions, much less genetically engineered, with only few exceptions. However, two of the genetically amenable Magnetospirillum species have emerged as tractable model organisms to study magnetosome formation and magnetotaxis. Recently, much has been revealed about the process of magnetosome biogenesis and dedicated structures for magnetosome dynamics and positioning, which suggest an unexpected cellular intricacy of these organisms. In this minireview, we summarize new insights and place the molecular mechanisms of magnetosome formation in the context of the complex cell biology of Magnetospirillum spp. First, we provide an overview on magnetosome vesicle synthesis and magnetite biomineralization, followed by a discussion of the perceptions of dynamic organelle positioning and its biological implications, which highlight that magnetotactic bacteria have evolved sophisticated mechanisms to construct, incorporate, and inherit a unique navigational device. Finally, we discuss the impact of magnetotaxis on motility and its interconnection with chemotaxis, showing that magnetotactic bacteria are outstandingly adapted to lifestyle and habitat.

Sign in / Sign up

Export Citation Format

Share Document