scholarly journals Symptoms and Quality of Life Changes after Hysteroscopic Treatment in Patients with Symptomatic Isthmocele—Preliminary Results

2021 ◽  
Vol 10 (13) ◽  
pp. 2928
Author(s):  
Monika Szafarowska ◽  
Magdalena Biela ◽  
Joanna Wichowska ◽  
Kamil Sobociński ◽  
Agnieszka Segiet-Święcicka ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Abnormal Uterine Bleeding ◽  
Life Changes ◽  
Social Psychological ◽  
Operative Hysteroscopy ◽  
Health Domains ◽  
The Difference ◽  
Positive Effect

Due to an increasing number of cesarean section deliveries, the common consequences of that surgery are observed more often in the population. One of them is the uterine cesarean scar defect known as niche or isthmocele. Most patients with that aliment are asymptomatic, but some of them can report abnormal uterine bleeding, pelvic pain, subfertility which can be the reason for reduced quality of life (QoL) of the patients. In our study, we analyzed the subjective feelings of changes in the severity of symptoms and quality of life of women with niche after diagnostic and operative hysteroscopy. The patients n = 85 included in the study group completed a follow up questionnaire six months after the procedure. Patients after operative hysteroscopy in comparison to patients after diagnostic procedure reported statistically significant reduction in post-menstruation bleeding/spotting and improvement in the quality of sexual activity. We have also noticed a higher pregnancy rate in the operative group, however, the difference was not statistically significant. According to our study, most women reported a positive effect of hysteroscopy on their QoL in social, psychological, environmental, and health domains.

Possibilities and prospects of conservative therapy for endometriosis, as a chronical progressing disease (review of literature)

GYNECOLOGY ◽  
2020 ◽  
Vol 22 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Tatyana Yu. Pestrikova ◽  
Elena A. Yurasova ◽  
Igor V. Yurasov
Keyword(s):  
Quality Of Life ◽  
Abnormal Uterine Bleeding ◽  
Modern Medicine ◽  
Reproductive Age ◽  
Aim Analysis ◽  
Scientific Publications ◽  
Terra Incognita ◽  
Positive Effect

Relevance. Endometriosis is a common gynecological disease that affects up to 10% of women of reproductive age worldwide and is the main cause of pain and infertility. Endometriosis is a disease, although it has been known for a long time, nevertheless, in many ways it represents terra incognita for modern medicine. Aim. Analysis of literature on the feasibility of long-term and the use of the drug dienogest 2 mg (Vizanne), which has a positive effect on the quality of life of patients with endometriosis. Materials and methods. To write this review, a search was made for domestic and foreign publications in Russian and international search engines (PubMed, eLibrary, etc.) over the past 13 years. The review included articles from peer-reviewed literature. Results. The review presents data on the difficulties of verifying the diagnosis of endometriosis due to a combination of this pathology with pain, infertility, abnormal uterine bleeding. The pathogenesis of the origin of endometriosis-associated pain is presented. The efficacy of the use of the drug dienogest (Vizanne), which has a powerful antiproliferative effect that reduces the main symptoms of endometriosis (pain, bleeding), is substantiated. The expediency of long-term and safe use of the drug dienogest (Vizanne), which has a positive effect on the quality of life of patients with endometriosis, has been proved. Conclusions. Numerous scientific publications confirm the feasibility of prolonged use of the drug dienogest (Vizanne), to achieve remission during endometriosis.

scholarly journals Patients with psychiatric diagnoses have lower quality of life than other patients with juvenile rheumatic disease: a prospective study

Rheumatology ◽  
2021 ◽  
Author(s):  
Silja Kosola ◽  
Heikki Relas
Keyword(s):  
Quality Of Life ◽  
Disease Activity ◽  
Transition Phase ◽  
University Hospital ◽  
Psychiatric Diagnoses ◽  
Adult Care ◽  
The Difference ◽  
Lower Hrqol

Abstract Introduction Transition of adolescents with chronic diseases from pediatric healthcare to adult care requires attention to maintain optimal treatment results. We examined changes in health-related quality of life (HRQoL) and disease activity among juvenile idiopathic arthritis (JIA) patients with or without concomitant psychiatric diagnoses after transfer to an adult clinic. Methods We prospectively followed 106 consecutive patients who were transferred from the New Children’s Hospital to the Helsinki University Hospital Rheumatology outpatient clinic between April 2015 and August 2019 and who had at least one follow-up visit. HRQoL was measured using 15D, a generic instrument. Results The patients’ median age at transfer was 16 years and disease duration 4.0 years. Patients were followed for a median of 1.8 years. Disease activity and overall HRQoL remained stable, but distress (dimension 13 of 15D) increased during follow up (P=0.03). At baseline, patients with at least one psychiatric diagnosis had lower overall 15D scores (0.89±0.14 vs. 0.95±0.05, P<0.01) and higher disease activity (Disease Activity Score 28; 1.88±0.66 vs. 1.61±0.31, P=0.01) than patients without psychiatric diagnoses. The difference in overall 15D persisted over the study period. Conclusions Transition phase JIA patients with psychiatric diagnoses had lower HRQoL than other JIA patients. Despite reduced disease activity and pain, HRQoL of patients with psychiatric diagnoses remained suboptimal at the end of follow-up. Our results highlight the necessity of comprehensive care and support for transition phase JIA patients.

Clinical Features of Graves' Ophthalmopathy and Impact of Enalapril on the Course of Mild Graves’ Ophthalmopathy: A Pilot Study

2020 ◽  
Vol 20 (1) ◽  
pp. 139-148 ◽  
Author(s):  
Ghazal Ataabadi ◽  
Mohammad H. Dabbaghmanesh ◽  
Naser Owji ◽  
Marzieh Bakhshayeshkaram ◽  
Nima Montazeri-Najafabady
Keyword(s):  
Quality Of Life ◽  
Pilot Study ◽  
Clinical Activity ◽  
Ophthalmological Examination ◽  
Graves Ophthalmopathy ◽  
Eye Examination ◽  
The Difference ◽  
Enalapril Treatment

Background: Inflammation, oxidative stress, and adipogenesis are associated with Graves’ ophthalmopathy (GO) progression. Objective: We conducted a pilot study to investigate the effect of Enalapril on patients with mild ophthalmopathy. Method: Based on the comprehensive eye examination, 12 patients with mild ophthalmopathy were selected from referred Graves’ patients and treated with Enalapril (5 mg daily) for 6 months. Clinical and ophthalmological examination [IOP (Intraocular Pressure), vision, Margin reflex distance and exophthalmia measurement, CAS (clinical activity score) and VISA [V (vision); I (inflammation/ congestion); S (strabismus/motility restriction); and A (appearance/exposure] score assessment) was performed at the beginning, 3 months and 6 months of the study period. Quality of life was also evaluated using a standard questionnaire. Results: Mean exophthalmia at the first visit was 18.75 ± 2.39, 3 months later 18.53 ± 2.39 and 6 months later was 17.92 ± 2.31, respectively. Mean CAS was 0.71 ± 0.82 (first visit), 0.57 ± 0.54 (3 months) and 0.14 ± 0.36 (6 months), respectively. Mean Margin reflex distance was 9.09 ± 4.36 (first visit) and 9.60 ± 4.40 (6 months), respectively. There were significant differences in the case of exophthalmia (P=0.002), CAS (P=0.006), and Margin reflex distance (P=0.029) between the first visit and 6 months after treatment. The difference between the score of quality of life in patients with GO after 6 months of follow up was statistically significant (P = 0.006). Conclusion: Our results showed that Enalapril treatment could ameliorate the clinical course of GO according to the ophthalmologic examinations and subjective parameters of disease progression. However, further studies should be performed to determine the efficacy of Enalapril in Graves’ ophthalmopathy treatment.

scholarly journals Quality of life changes following inpatient and outpatient treatment in obsessive-compulsive disorder: a study with 12 months follow-up

2013 ◽  
Vol 12 (1) ◽  
pp. 4 ◽  
Author(s):  
Elisabeth Hertenstein ◽  
Nicola Thiel ◽  
Nirmal Herbst ◽  
Tobias Freyer ◽  
Christoph Nissen ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Obsessive Compulsive Disorder ◽  
Outpatient Treatment ◽  
Life Changes ◽  
Obsessive Compulsive ◽  
Compulsive Disorder

scholarly journals Normal Quality of Life after the Cox-Maze Procedure for Atrial Fibrillation

2008 ◽  
Vol 3 (3) ◽  
pp. 142-146 ◽  
Author(s):  
Spencer J. Melby ◽  
Andreas Zierer ◽  
Jordon G. Lubahn ◽  
Marci S. Bailey ◽  
James L. Cox ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
Short Form ◽  
Maze Procedure ◽  
Medical Outcomes ◽  
Health Domains ◽  
The Mean

Objective Atrial fibrillation (AF) has been shown in numerous studies to significantly decrease patient's quality of life. The Cox-Maze procedure has excellent long-term efficacy in curing AF. However, it is unknown whether this procedure improves long-term quality of life in these patients. The purpose of this study was to examine late quality of life in patients who underwent a lone Cox-Maze procedure. Methods Between 1987 and 2003, 163 patients underwent a Cox-Maze procedure for lone AF at our institution. Of these, 68 patients agreed and completed the Medical Outcomes Study Short Form 36 Health Survey. Scores from the age-matched general U.S. population were normalized to a mean of 50 and standard deviation of 10 to facilitate comparison. Collected data were compared with the norm-based score for each domain using a one-sample t test. Four patients were removed from the analysis because of AF recurrence. Results There were 52 males (81%). Mean age was 52.6 ± 9.5 years. Preoperatively, 37 patients (58%) had paroxysmal and 25 patients (39%) had persistent or permanent AF. The mean duration of AF before surgery was 9.8 ± 8.2 years. There was no statistical difference in norm-based scores between the Cox-Maze procedure group and the age-matched general U.S. population in any of the eight health domains at a mean follow-up of 8.7 ± 3.7 years. Conclusion Our results suggest that the Cox-Maze procedure cures AF in the majority of patients, and that those patients who are cured had a normal quality of life when compared with the general population at late follow-up.

Neuropsychological and Quality of Life Changes Following Unilateral Thalamic Deep Brain Stimulation in Parkinson's Disease: A One-Year Follow-up

2001 ◽  
Vol 143 (12) ◽  
pp. 1273-1278 ◽  
Author(s):  
S. P. Woods ◽  
J. A. Fields ◽  
K. E. Lyons ◽  
W. C. Koller ◽  
S. B. Wilkinson ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Life Changes ◽  
One Year ◽  
Deep Brain

scholarly journals Quality of life more than 10 years after radiotherapy for localized prostate cancer—impact of time after treatment and prescription dose

2020 ◽  
Author(s):  
Michael Pinkawa ◽  
Amr Gharib ◽  
Marsha Schlenter ◽  
Ludmila Timm ◽  
Michael J. Eble
Keyword(s):  
Quality Of Life ◽  
Prostate Cancer ◽  
Sexual Function ◽  
Urinary Continence ◽  
Life Changes ◽  
Stool Incontinence ◽  
Prescription Dose ◽  
The Impact

Abstract Purpose Analysis of quality of life changes after radiotherapy with focus on the impact of time after treatment and prescription dose. Methods Consecutive patients were treated with doses from 70.2/1.8 Gy (n = 206) to 72/1.8–2.0 Gy (n = 176) in a single centre and surveyed using the Expanded Prostate Cancer Index Composite questionnaire. Results Urinary and bowel bother scores decreased 1 / 3 / 6 points and 7 / 7 / 9 points on average 1 / 5 / 10 years after RT in comparison to baseline scores. The rate of urinary (need of pads in 8% vs. 15% before vs. 10 years after RT; p = 0.01) and bowel (uncontrolled leakage of stool in 5% vs. 12% before vs. 10 years after RT; p < 0.01) incontinence, as well as rectal bleeding (4% vs. 8% before vs. 10 years after RT; p = 0.05) increased. Sexual function scores decreased (erections sufficient for intercourse in 36% vs. 12% before vs. 10 years after RT; p < 0.01). A higher dose had a statistically significant impact on urinary bother and stool incontinence, but also tended to decrease urinary continence. Age and comorbidities did not have an influence on score changes, but on baseline urinary function/bother and baseline sexual function. Conclusion Apart from an increasing rate of erectile dysfunction, urinary and bowel incontinence rates increased with increasing follow-up period. A higher dose was found to be associated with increased urinary problems and larger stool incontinence rates. Age and comorbidities were found to be relevant for baseline scores, but not for score changes.

scholarly journals Prevalence of Depression, Adherence, and Quality of Life in Advance Chronic Kidney Disease and Hemodialysis Patients: A Prospective Follow-up Study

2021 ◽  
Author(s):  
Muhammad Daoud Butt ◽  
Rahma Zahid Butt ◽  
Fatima Zahid Butt ◽  
Fawad Rasool ◽  
Zaheer-Ud-Din Babar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Rating Scale ◽  
Well Being ◽  
Sf 36 ◽  
Health Domains ◽  
Patient Groups

Abstract Background: Many patients with end-stage renal disease (ESRD) have poor physical and mental health, little is known about these health domains in individuals with advanced chronic kidney disease (CKD). The study aimed to study how symptoms, depression, and health-related quality of life (HRQoL) differed between ESRD and CKD patients.Methodology: Patients with ESRD and those with advanced CKD are included in the study. The Morisky Lewis Greens Adherence measures, Hamilton Depression Rating Scale, and KDQOL-SF-36 were used to assess patients' adherence, depression, and HRQoL, and these health domains were compared between patient groups. Results: A total of 314 patients participated in the study, the mean age of participants was 54.64±15.33. Hypertension and diabetes remained the predominant comorbid conditions with prevalence rates of 64.2% and 74.6%, respectively which is significantly higher level of depression observed , which also deteriorates follow-up periods in both groups of patients. The anemic condition remained the major problem among patients with ESRD. The results show thay the overall HRQoL domain and scale parameters were deteriorating the follow-up period. Scores on the SF-36 Physical Component Summary and the SF-36 Mental Component Summary were similar. Conclusions: Patients with ESRD and advanced CKD have similar symptom burdens, depression rates, and poor HRQoL. Given the well-known impairments in both patient groups, the findings of this study highlight the significant decline in the physical and psychological well-being of CKD patients.

scholarly journals Abnormal Uterine Bleeding in Adolescent

2021 ◽  
Vol 6 (1) ◽  
pp. 1254-1257
Author(s):  
Kms Yusuf Effendi ◽  
Rizani Amran ◽  
Iskandar Zulqarnain ◽  
Heriyadi Manan ◽  
Adnan Abadi ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hormonal Therapy ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Comprehensive Treatment ◽  
Hemodynamic Stability ◽  
Common Etiology ◽  
Abnormal Bleeding

Abnormal uterine bleeding (AUB) is defined as the abnormal bleeding from the uterine corpus in term of duration, volume, frequency and/or regularity. This condition occurs in 37% of adolescents and may affect the quality of life and increased hospitalization. Etiology is divided into structural and non-structural causes, known as PALM-COEIN. The most common etiology in adolescents is anovulatory menstruation due to immature hypothalamus-hypophysis axis. Diagnostic evaluation should include investigation in the etiology of AUB, anemia signs, and hemodynamic status. Treatment of AUB consists of hormonal and non-hormonal therapy. Therapy in adolescent is given based on the severity of bleeding, grading of anemia, and hemodynamic stability. Follow-up is required after therapy. Understanding AUB in adolescents can help clinicians deliver appropriate and comprehensive treatment. This review was aimed to explain about definition, epidemiology, etiology, pathophysiology, diagnosis, and treatment of abnormal uterine bleeding in adolescent.

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