scholarly journals How to Explore an Endocrine Cause of Hypertension

2022 ◽  
Vol 11 (2) ◽  
pp. 420
Author(s):  
Jean-Baptiste de Freminville ◽  
Laurence Amar
Keyword(s):  
Blood Pressure ◽  
Cushing Syndrome ◽  
Adult Population ◽  
Delayed Diagnosis ◽  
Specific Treatment ◽  
Uncontrolled Blood Pressure ◽  
Hypertensive Patients ◽  
The World ◽  
Patients At Risk ◽  
Secondary Causes

Hypertension (HTN) is the most frequent modifiable risk factor in the world, affecting almost 30 to 40% of the adult population in the world. Among hypertensive patients, 10 to 15% have so-called “secondary” HTN, which means HTN due to an identified cause. The most frequent secondary causes of HTN are renal arteries abnormalities (renovascular HTN), kidney disease, and endocrine HTN, which are primarily due to adrenal causes. Knowing how to detect and explore endocrine causes of hypertension is particularly interesting because some causes have a cure or a specific treatment available. Moreover, the delayed diagnosis of secondary HTN is a major cause of uncontrolled blood pressure. Therefore, screening and exploration of patients at risk for secondary HTN should be a serious concern for every physician seeing patients with HTN. Regarding endocrine causes of HTN, the most frequent is primary aldosteronism (PA), which also is the most frequent cause of secondary HTN and could represent 10% of all HTN patients. Cushing syndrome and pheochromocytoma and paraganglioma (PPGL) are rarer (less than 0.5% of patients). In this review, among endocrine causes of HTN, we will mainly discuss explorations for PA and PPGL.

scholarly journals Is the Association of Diabetes With Uncontrolled Blood Pressure Stronger in Mexican Americans and Blacks Than in Whites Among Diagnosed Hypertensive Patients?

2013 ◽  
Vol 26 (11) ◽  
pp. 1328-1334 ◽  
Author(s):  
Xuefeng Liu ◽  
Ping Song
Keyword(s):  
Blood Pressure ◽  
Racial Differences ◽  
Mexican Americans ◽  
The United States ◽  
Linear Regression Models ◽  
Uncontrolled Blood Pressure ◽  
Hypertensive Patients ◽  
Health And Nutrition ◽  
Multistage Design ◽  
Hispanic White

Abstract BACKGROUND Clinical evidence shows that diabetes may provoke uncontrolled blood pressure (BP) in hypertensive patients. However, racial differences in the associations of diabetes with uncontrolled BP outcomes among diagnosed hypertensive patients have not been evaluated. METHODS A total of 6,134 diagnosed hypertensive subjects aged ≥20 years were collected from the National Health and Nutrition Examination Survey 1999–2008 with a stratified multistage design. Odds ratios (ORs) and relative ORs of uncontrolled BP and effect differences in continuous BP for diabetes over race/ethnicity were derived using weighted logistic regression and linear regression models. RESULTS Compared with participants who did not have diabetes, non-Hispanic black participants with diabetes had a 138% higher chance of having uncontrolled BP, Mexican participants with diabetes had a 60% higher chance of having uncontrolled BP, and non-Hispanic white participants with diabetes had a 161% higher chances of having uncontrolled BP. The association of diabetes with uncontrolled BP was lower in Mexican Americans than in non-Hispanic blacks and whites (Mexican Americans vs. non-Hispanic blacks: relative OR = 0.55, 95% confidence interval (CI) = 0.37–0.82; Mexican Americans vs. non-Hispanic whites: relative OR = 0.53, 95% CI = 0.35–0.80) and the association of diabetes with isolated uncontrolled systolic BP was lower in Mexican Americans than in non-Hispanic whites (Mexican Americans vs. non-Hispanic whites: relative OR = 0.62, 95% CI = 0.40–0.96). Mexican Americans have a stronger associaton of diabetes with decreased systolic BP and diastolic BP than non-Hispanic whites, and a stronger association of diabetes with decreased diastolic BP than non-Hispanic blacks. CONCLUSIONS The association of diabetes with uncontrolled BP outcomes is lower despite higher prevalence of diabetes in Mexican Americans than in non-Hispanic whites. The stronger association of diabetes with BP outcomes in whites should be of clinical concern, considering they account for the majority of the hypertensive population in the United States.

PREVENTION AND MANAGEMENT OF HYPERTENSION W. S. R. TO AYURVEDA: REVIEW ARTICLE

2020 ◽  
Vol 8 (06) ◽  
Author(s):  
Dr. Sandip Tawade
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Dietary Habits ◽  
Adult Population ◽  
Medical Science ◽  
Good Health ◽  
Healthy Person ◽  
Review Article ◽  
Unhealthy Lifestyle ◽  
The World

Ayurveda is not only an ancient medical science but it is a complete life science.The main aim of Ayurveda is to maintain the health of a healthy person & to cure the disease of diseased person. From last few decades due to globalisation there is drastic change in working pattern, dietary habits & lifestyle. According to a new research, lifestyle diseases replaced traditional health risk factors resulting in an increase in incidents of diseases & deaths in India in the last two decades. Now most of the diseases & deaths are caused by High Blood Pressure, high cholesterol, obesity, alcohol use and poor diet. Unhealthy lifestyle is the root cause of many diseases broadly termed as lifestyle disorder. Hypertension is the most common lifestyle disease affecting population all over the world. About 26.4% of the world adult population in 2020 had hypertension and 29.2% were projected to have this condition by 2025. India is labeled as global capital of hypertension. The Ayurveda concentrates on achieving the promotion of health, prevention and management of disease for a healthy and happy life in the ailing society. The principals of Ayurveda are focused on maintaining good health by good diet and good lifestyle. Proper dietary habits, proper exercise, Yoga, Meditation along with Ayurveda herbs can be beneficial to balancing of mind, which reduce stress and maintain the blood pressure. The present review article is aimed that the planning of proper herbal medications as per Ayurveda guidelines will definitely control the high blood pressure without any hazardous side effects of drugs.

scholarly journals Awareness and Practices of Non-Pharmacological Approaches for Management of Hypertension in a Geriatric Population

2014 ◽  
Vol 2 (2) ◽  
pp. 53-55
Author(s):  
Debalina Sahoo ◽  
Harshida Gosai ◽  
Ujjwal Sahoo ◽  
J.M. Harsoda
Keyword(s):  
Public Health ◽  
Blood Pressure ◽  
Salt Intake ◽  
Normal Values ◽  
Geriatric Population ◽  
Hypertensive Patients ◽  
Hypertensive Population ◽  
The World ◽  
Study Population

Background: There is an increase in the prevalence of hypertension all over the world, including India. Hypertension can be initially managed with non-pharmacological measures. This study aims to assess the knowledge of non-pharmacological measures to control hypertension and its application in a geriatric hypertensive population. Methods: The study was conducted at the Department of Physiology, SVU, Vadodara, India. A total 110 hypertensive patients were included in the study and a non-validated survey was conducted to examine knowledge of non-pharmacological measures to control hypertension in this group of patients. Frequencies, percentages, means and standard deviations were calculated and reported. Results: Only 10% of the respondents knew the normal values for blood pressure. Approximately 38% of the subjects did not measure their blood pressure regularly. A total of 24% subjects knew that body weight has a correlation with hypertension. About 27% said that there was no correlation between salt intake and hypertension, and 88% of the study population did not carry out any form of physical activity. Conclusion: Hypertension can be controlled by life style modifications such as exercise, weight management and a healthy diet. Public health and education measures targeting hypertensive population need to be taken to decrease the risk factors for cardiovascular diseases and, therefore, improve people's health and quality of life.

scholarly journals Influence of dietary and lifestyle factors on blood pressure control among adult hypertensive patients under care in Uganda

2021 ◽  
Author(s):  
Patience Annet Nakalega ◽  
Levicatus Mugenyi ◽  
Lilian Nuwabaine ◽  
Mathius Amperiize ◽  
Barbara Kirunda Tabusibwa
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Lifestyle Factors ◽  
Dietary Factors ◽  
Poor Adherence ◽  
Uncontrolled Blood Pressure ◽  
Hypertensive Patients ◽  
Factors Associated ◽  
Study Participants

Abstract Background Hypertension is an important worldwide public-health challenge because of its high prevalence and for being a risk factor for cerebrovascular, cardiovascular and chronic renal disease. Despite these risk factors, blood pressure control among hypertensive patients is still poor. Objectives To assess dietary and lifestyle factors associated with uncontrolled blood pressure control among a series of Ugandan hypertensive patients under care at a Kiruddu hospital.Methods A cross sectional study involving 271 adult hypertensive patients attending general outpatient hypertensive clinic were enrolled. We collected data on dietary and lifestyle factors, social demographics, BMI, comorbidities, and adherence to hypertensive medication. Dietary factors were based on recommended DASH diet including nine food items salt; grains; fruits; vegetables; nut/seeds, and legumes; dairy; meat; fat; and sweets. Questionnaires on alcohol intake, smoking status and level of physical activity were also administered. An average of the previous two Blood pressure readings were recorded while weight and height were measured for each subject at enrolment. Factors associated with uncontrolled blood pressure (>140/90mmHg) were assessed using a multivariate logistic regression model.Results The mean age of study participants was 57 years (SD ± 0.76 years), with female dominance (77.9%). Among the study participants, 121 (44.7%) had uncontrolled BP. Dietary factors that remained significantly associated with uncontrolled blood pressure with adjusted OR (95%CI) included consumption of raw salt: 4.18 (1.32-13.24) and inadequate fruit consumption (less than 7days/week): 2.18 (1.26-3.75) while clinical factors included being overweight: 2.51 (1.27-4.95) and poor adherence to antihypertensive medications prescribed: 1.82 (1.03-3.21).Conclusion The proportion of hypertensive patients with uncontrolled BP was high (44.7%). Consumption of raw salt, inadequate fruit consumption being overweight and poor adherence to antihypertensive medication were significantly associated with uncontrolled BP. From these findings, many of the factors that impact on the control of blood pressure are fortunately modifiable.

scholarly journals ASSOCIATION OF DIETARY AND LIFESTYLE FACTORS ON BLOOD PRESSURE CONTROL AMONG ADULT HYPERTENSIVE PATIENTS ATTENDING A UGANDAN TERTIARY HOSPITAL

2021 ◽  
Vol 2 (2) ◽  
pp. 103-114
Author(s):  
A. P. Nakalega ◽  
L. Mugenyi ◽  
L. Nuwabaine ◽  
M. Amperiize ◽  
K. B. Tabusibwa
Keyword(s):  
Blood Pressure ◽  
Blood Pressure Control ◽  
Pressure Control ◽  
Lifestyle Factors ◽  
Poor Adherence ◽  
Fruit Consumption ◽  
Uncontrolled Blood Pressure ◽  
Hypertensive Patients ◽  
Factors Associated ◽  
Study Participants

Hypertension is an important worldwide public-health challenge due to its high prevalence and being a risk factor for cerebrovascular, cardiovascular, and chronic renal diseases. Despite these risk factors, blood pressure control among hypertensive patients is still poor.  The main objective was to assess dietary and lifestyle factors associated with uncontrolled blood pressure control among Ugandan hypertensive patients at Kiruddu hospital. Materials and methods: A cross-sectional study involving 271 adult hypertensive patients attending the outpatient hypertensive clinic was enrolled. Data were obtained on dietary, lifestyle factors (alcohol intake, smoking status, and level of physical activity), social demographics, Body Mass Index (BMI), comorbidities, and adherence to hypertensive medication. An average of the current and previous two Blood pressure readings was recorded. Factors associated with uncontrolled blood pressure were assessed using a multivariate logistic regression model. Results: The mean age of study participants was 57 ± 0.76 years, with female dominance (77.9%). Among the study participants, 121 (44.7%) had uncontrolled BP. Dietary factors that were associated with uncontrolled blood pressure with adjusted OR (95%CI) included consumption of raw salt: 4.18 (1.32-13.24) and inadequate fruit consumption: 2.18 (1.26-3.75) while clinical factors included being overweight: 2.51 (1.27-4.95) and poor adherence to antihypertensive medications prescribed: 1.82 (1.03-3.21). Conclusion: The proportion of hypertensive patients with uncontrolled Blood Pressure was high (44.7%). Consumption of raw salt, inadequate fruit consumption, being overweight and poor adherence to antihypertensive medication were significantly associated with uncontrolled BP. From these findings, factors that were associated with the control of blood pressure are modifiable.

scholarly journals The Effect of Autogenic Relaxation on Blood Pressure in Hypertensive Patients

2021 ◽  
Vol 10 (1) ◽  
pp. 44
Author(s):  
Anita Shinta Kusuma ◽  
Evin Kristiani
Keyword(s):  
Blood Pressure ◽  
Body Awareness ◽  
Pharmacological Therapy ◽  
The Body ◽  
World Health ◽  
Control Blood Pressure ◽  
Relaxation Methods ◽  
Hypertensive Patients ◽  
The World ◽  
Autogenic Relaxation

Hypertension case is increasing from year to years. Based on World Health Organization (WHO) data in 2015 showed around 1.13 billion people in the world have hypertension, meaning 1 in 3 people in the world are diagnosed with hypertension. Hypertension is often referred to as a "silent killer", because many people with hypertension do not feel any signs and symptoms, and then after some years they experience complications. One way to control blood pressure in hypertensive patients is to use non-pharmacological therapy interventions. One of them is to use autogenic relaxation methods. Autogenic relaxation is a method that comes from self and body awareness by controlling muscle and liver tension for the improvement of high blood pressure caused mainly by stress. Autogenic relaxation will help the body to carry commands through autosuggestion to relax so that it can control blood pressure, heart rate and body temperature. The purpose of this study is to describe the influence of autogenic relaxation to decrease the blood pressure of hypertensive patients. This study uses the literature review method. The result of this study shows that several literatures on autogenic relaxation proved that this intervention is very effective for hypertensive patients and can be used as a complementary intervention in hypertensive patients.

scholarly journals The effectiveness of the replacement of the generic blockers of the renin-angiotensin-aldosterone system by perindopril arginine in patients with uncontrolled blood pressure: the results of the regional program “DIFFERENCE”

2018 ◽  
Vol 24 (3) ◽  
pp. 359-368
Author(s):  
N. N. Nikulina
Keyword(s):  
Blood Pressure ◽  
Calcium Antagonist ◽  
Angiotensin Ii ◽  
Generic Drugs ◽  
Uncontrolled Blood Pressure ◽  
Hypertensive Patients ◽  
Receptor Blockers ◽  
The Mean ◽  
Study Completion ◽  
Design And Methods

Taking into account the widespread use of generic drugs and insufficient rate of achieving the target blood pressure (BP), a regional program “DIFFERENCE” was initiated. The purpose of this study was to assess the chance of increasing the effectiveness of antihypertensive therapy (AHT) by replacing generic perindopril and receptor blockers to angiotensin II (BRA) by the original perindopril and generic indapamide by the original one.Design and methods. The study included 330 hypertensive patients (47,3% males; the average age of men is 53,5 ± 8,5 years, women — 54,2 ± 10,2 years, p > 0,05). The mean systolic BP was 149,5 ± 5,3 mm Hg, average diastolic BP — 96,4 ± 4,9 mm Hg; 1st HTN degree was achieved in 49,1% patients, 2nd — in 41,2%; 3rd degree remained in 9,7%. Monotherapy of HTN was prescribed in 79,4% patients.Results. After the transfer from the generic perindopril to the original drug (± transfer from the generic indapamide to the original one) within 4 weeks no other changes of AHT were introduced. During these 4 weeks, the average systolic BP decreased to 139,1 ± 5,1 mm Hg, diastolic blood pressure declined to 88,2 ± 5,8 mm Hg, which allowed to achieve the target BP in 37,0% patients (p < 0,01). On the Month 1 visit, taking into account indications, the frequency of combined AHT increased to 76,4%, on the Month 3 visit — to 88,2%, exceeding the original one by 4,3 times (p < 0,01). On the Month 3 visit the average systolic BP was 136,5 mm Hg, diastolic BP — 85,9 mm Hg, the target BP level was achieved in 53,9% cases (p < 0,01). By the study completion, the most often combination included perindopril with diuretic or calcium antagonist.Conclusions. The study “DIFFERENCE” demonstrated the effectiveness of the replacement of generic perindopril and BRA by the original perindopril combined, if necessary, with the replacement of generic indapamide by the original one in patients wth uncontrolled HTN. To date, the combined AHT has not been assigned frequently enough, which is also the reason for the insufficient efficiency. The most common were the combinations of perindopril with diuretic or calcium antagonist. 

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