scholarly journals What Pediatricians Should Know Before Studying Gut Microbiota

2019 ◽  
Vol 8 (8) ◽  
pp. 1206 ◽  
Author(s):  
Drago ◽  
Panelli ◽  
Bandi ◽  
Zuccotti ◽  
Perini ◽  
...  
Keyword(s):  
Human Physiology ◽  
Data Analysis ◽  
Sampling Methods ◽  
Basic Knowledge ◽  
Gene Interactions ◽  
Vital Organ ◽  
Sample Collection ◽  
Exclusion Criteria ◽  
Molecular Approaches ◽  
Insight Into

Billions of microorganisms, or “microbiota”, inhabit the gut and affect its homeostasis, influencing, and sometimes causing if altered, a multitude of diseases. The genomes of the microbes that form the gut ecosystem should be summed to the human genome to form the hologenome due to their influence on human physiology; hence the term “microbiome” is commonly used to refer to the genetic make-up and gene–gene interactions of microbes. This review attempts to provide insight into this recently discovered vital organ of the human body, which has yet to be fully explored. We herein discuss the rhythm and shaping of the microbiome at birth and during the first years leading up to adolescence. Furthermore, important issues to consider for conducting a reliable microbiome study including study design, inclusion/exclusion criteria, sample collection, storage, and variability of different sampling methods as well as the basic terminology of molecular approaches, data analysis, and clinical interpretation of results are addressed. This basic knowledge aims to provide the pediatricians with a key tool to avoid data dispersion and pitfalls during child microbiota study.

PERSEPSI WISATAWAN TERHADAP OBJEK WISATA PULAU BOKORI DI DESA BOKORI KECAMATAN SOROPIA KABUPATEN KONAWE

2018 ◽  
Vol 3 (2) ◽  
pp. 181
Author(s):  
Rahmat Rahmat
Keyword(s):  
Data Analysis ◽  
Data Collection ◽  
Qualitative Method ◽  
Average Score ◽  
Questionnaire Data ◽  
Sample Collection ◽  
Average Rating ◽  
Quota Sampling ◽  
Descriptive Qualitative

This study aims to determine the Tourist Perception of Bokori Island Tourism Object in Bokori Village, Soropia District of Konawe Regency. This study used descriptive qualitative method. Subjects in this study were tourists visiting attractions Bokori Island. Traveler sampling in this study set out in the quota sampling 50 respondents, in this study the sample collection technique by accidental sampling.Methods of  data collection using questionnaires, observation and documentation. Questionnaire data analysis in this research is the analysis presented in the table percentage and distribution. Based on the results obtained show that, according to the perception of tourists attractions of the Bokori Island (1) appeal to the average score - average rating of 3.31 with the perception of being in either category, (2) accessibility with a mean score - average of 3.40 with the perception of tourists are in good category, (3) visitor facilities with a mean score - average rating of 3.12 with the perception of being in either category, (4) infrastructure with a mean score - average 3.53 with the perception of tourists were in the excellent category, (5) security with a mean score - average of 3.24 with the perceptions of visitors are in good category, (6) the promotion with a mean score - average of 3.32 with the perceptions of visitors are in either category. Thus the perception of the overall rating showed a mean score - average rating of 3.32 with the perception of being in either category.

Contaminated flexible endoscopes: Review of impact of channel sampling methods on culture results and recommendations for root-cause analysis

2021 ◽  
pp. 1-16
Author(s):  
Michelle J. Alfa ◽  
Harminder Singh
Keyword(s):  
Sampling Methods ◽  
Root Cause Analysis ◽  
Multidrug Resistant ◽  
Transmission Risk ◽  
Remedial Action ◽  
Sample Collection ◽  
Cause Analysis ◽  
Infection Transmission ◽  
Root Cause ◽  
Critical Aspects

Abstract Recently, infection transmission risk associated with contaminated, patient-ready flexible endoscopes has attracted attention. Outbreaks of multidrug-resistant organisms resulting in infection and/or colonization have been particularly concerning. Recent CDC and FDA recommendations focus on reducing “exogenous” infection transmission and specifically recommend that endoscopy sites have quality systems in place for endoscope reprocessing. Another key recommendation is the culture of patient-ready endoscopes to detect contamination with organisms of concern. Remaining gaps in the guidelines include ensuring that optimal endoscope-channel sample methods are used and ensuring effective root-cause analysis and remediation when contamination is detected. In this review, we summarize the critical aspects of endoscope sample collection and present a practical approach to root-cause analysis and remedial action plans.

scholarly journals Preparing to Take the Field: A Temporal Exploration of Stress, Emotion, and Coping in Elite Cricket

2016 ◽  
Vol 30 (2) ◽  
pp. 101-112 ◽  
Author(s):  
Adam James Miles ◽  
Rich Neil ◽  
Jamie Barker
Keyword(s):  
Data Analysis ◽  
Coping Strategies ◽  
Relational Theory ◽  
Semistructured Interviews ◽  
And Behaviors ◽  
And Coping ◽  
Insight Into

The purpose of this study was to explore the stress, emotion, and coping (SEC) experiences of elite cricketers leading up to and on the day of their first competitive fixture of the season. Four elite male cricketers (M = 21.25, SD = 1.5) completed Stress and Emotion Diaries (SEDs) for the 7-day period leading up to and on the day of their first competitive fixture of the season. We then interviewed the cricketers to explore the content of the SEDs in more detail. We used semistructured interviews to glean insight into the stressors, cognitions, emotions, coping strategies, and behaviors. Inductive and deductive content data analysis provided a holistic and temporal exploration of the SEC process underpinned by the cognitive-motivational-relational theory of emotions (Lazarus, 1999). The results highlighted the ongoing and continuous nature of the SEC process while illustrating the coping strategies the cricketers used leading up to and on the day of competition.

scholarly journals BOWEL PREPARATION BEFORE COLONOSCOPY FOR CHILDREN: comparison of efficacy of three different methods

2015 ◽  
Vol 52 (4) ◽  
pp. 311-314
Author(s):  
Seyed Mohsen DEHGHANI ◽  
Hazhir JAVAHERIZADEH ◽  
Mahmood HAGHIGHAT ◽  
Mohammad-Hadi IMANIEH ◽  
Saeed GHANBARI
Keyword(s):  
Data Analysis ◽  
Polyethylene Glycol ◽  
Bowel Preparation ◽  
Normal Saline ◽  
Therapeutic Procedure ◽  
Previous Surgery ◽  
Exclusion Criteria ◽  
Significant Difference ◽  
History Of

Background - Colonoscopy is an important diagnostic and therapeutic procedure. Adequate bowel preparation is mandatory. Several regimens were discussed in the literature. Among the drugs which has recently used, polyethylene glycol is one of the most popular agents. Objectives - The aim of this study was to compare efficacy of three different methods for 1 day preparation before colonoscopy. Methods - This study included children with the range of ages (2-21) who had an indication of colonoscopy. Exclusion criteria were based on the history of previous surgery, parental disagreement, and patients who did not use preparation protocol. Three methods for bowel preparation were studied: 1- Polyethylene glycol only; 2- Polyethylene glycol and bisacodyl suppositories; 3- Polyethylene glycol plus normal saline enema. Boston Bowel Preparation Score was used for evaluation of preparation. SPSS version 16.0 (Chicago, IL, USA) were used for data analysis. Results - In this study 83 cases completed the bowel preparation completely. Acceptable bowel preparation was seen in 24 (85.71%), 36 (94.73%), and 14 (82.35%) of cases in PEG, PEG + bisacodyl, and PEG + normal saline enema groups respectively. PEG + bisacodyl suppositories was more effective than PEG + normal saline for the preparation of the first segment ( P=0.05). For second and third segment of colon, BPPS score was higher in PEG + bisacodyl suppositories compared to other regimens, but this difference was not statistically significant. Conclusion - There was no significant difference between 1 day colonoscopy regimens in terms of bowel preparation score. Lowest score was seen in PEG + enema group compared to other group.

scholarly journals Pengaruh Kompetensi, Independensi, Dan Etika Auditor Terhadap Kualitas Audit Aparat Inspektorat

2020 ◽  
Vol 2 (4) ◽  
pp. 3737-3754
Author(s):  
Witta Widiya ◽  
Efrizal Syofyan
Keyword(s):  
Regression Analysis ◽  
Data Analysis ◽  
Data Collection ◽  
Sampling Method ◽  
Audit Quality ◽  
Primary Data ◽  
Sample Collection ◽  
The Third ◽  
Data Analysis Methods

The purpose of this study was to analyze the effect of competency, independence, and auditor ethics on audit quality in Inspectorate Office. Type of this research is a quantitative researh. The population in this study were auditors in inspectorate office West Sumatera province with 35 samples taken. The technique of sample collection is total sampling method. The sources of the data of this research is the primary data. The technique of the data collection is questionnaires. The data were analyzed using multiple regression analysis using SPSS version 25. Data analysis methods used in this study are multiple linier regression analysis, with audit quality as the dependent variabel, competency, independence and auditor ethics as the independent variabel. This result of the reseacrh support the third hypotheses, where the research shows that auditor ethics has an effect on audit quality of examiners at the inspectorate West Sumatera province. The results also show that competency and independence have no effect on audit quality of examiners at the inspecorate West Sumatera provinsi.

scholarly journals Conserved Mechanisms, Novel Anatomies: The Developmental Basis of Fin Evolution and the Origin of Limbs

Diversity ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 384
Author(s):  
Amanda N. Cass ◽  
Ashley Elias ◽  
Madeline L. Fudala ◽  
Benjamin D. Knick ◽  
Marcus C. Davis
Keyword(s):  
Gene Expression ◽  
Linear Connection ◽  
Expression Data ◽  
Evolutionary Novelty ◽  
Model Species ◽  
Animal Evolution ◽  
Molecular Approaches ◽  
Key Aspects ◽  
Insight Into ◽  
Appendage Patterning

The transformation of paired fins into tetrapod limbs is one of the most intensively scrutinized events in animal evolution. Early anatomical and embryological datasets identified distinctive morphological regions within the appendage and posed hypotheses about how the loss, gain, and transformation of these regions could explain the observed patterns of both extant and fossil appendage diversity. These hypotheses have been put to the test by our growing understanding of patterning mechanisms that regulate formation of the appendage axes, comparisons of gene expression data from an array of phylogenetically informative taxa, and increasingly sophisticated and elegant experiments leveraging the latest molecular approaches. Together, these data demonstrate the remarkable conservation of developmental mechanisms, even across phylogenetically and morphologically disparate taxa, as well as raising new questions about the way we view homology, evolutionary novelty, and the often non-linear connection between morphology and gene expression. In this review, we present historical hypotheses regarding paired fin evolution and limb origins, summarize key aspects of central appendage patterning mechanisms in model and non-model species, address how modern comparative developmental data interface with our understanding of appendage anatomy, and highlight new approaches that promise to provide new insight into these well-traveled questions.

scholarly journals ANALISIS PENGARUH KOMPENSASI TERHADAP PRODUKTIVITAS KERJA KARYAWANCOCA-COLA INDONESIA

2017 ◽  
Vol 4 (2) ◽  
pp. 30
Author(s):  
Lite Lite
Keyword(s):  
Data Analysis ◽  
Work Environment ◽  
Multiple Regression ◽  
Work Productivity ◽  
Influential Factors ◽  
Essential Factor ◽  
Sample Collection ◽  
Production Section ◽  
National Welfare ◽  
A Company

There is a universal awareness on the importance of productivity in improving national welfare. The productivity is an essential factor in maintaining and developing the success of an organization. So that a company can achieve its goals one of which to improve the work productivity, then it is an obligation for the leaders to provide motivation for the employees in the form of compensation.This research is willing to achieve the goals namely (1) to determine the effects of salary, intensive, facility, position promotion and work environment on the work productivity of CocaCola Indonesia employees either simultaneously or partially (2) to determine the most influential factors on the work productivity of CocaCola Indonesia employees.In this research, the population is all of the employees in production section CocaColaIndonesia. There are 130 employees as the research samples. The sample collection technique is bypurposivesampling   technique. The data analysis tools used in this research are validity, reliability, classical assumption test, multiple regression, determination coefficient and hypothesis testing.Results of the research are (1) There are effects of salary on the employee work productivity (2)There are effects of incentive on the employee work productivity (4) There are effects of work environment on the employee work productivity (5) There are significant effects of salary (X1),incentive (X2)allowances (X3),facility (X4), position promotion (X5) and work environment (X6) simultaneously on the work productivity (Y). The salary has the dominant effects on the work productivity namely by b1=0,248.

A systematic view on data descriptors for the visual analysis of tabular data

2016 ◽  
Vol 16 (3) ◽  
pp. 232-256 ◽  
Author(s):  
Hans-Jörg Schulz ◽  
Thomas Nocke ◽  
Magnus Heitzler ◽  
Heidrun Schumann
Keyword(s):  
Data Analysis ◽  
Visual Analysis ◽  
Data Gathering ◽  
Climate Impact ◽  
General Concept ◽  
Basic Knowledge ◽  
Data Types ◽  
Process Data ◽  
Tabular Data ◽  
Analysis Process

Visualization has become an important ingredient of data analysis, supporting users in exploring data and confirming hypotheses. At the beginning of a visual data analysis process, data characteristics are often assessed in an initial data profiling step. These include, for example, statistical properties of the data and information on the data’s well-formedness, which can be used during the subsequent analysis to adequately parametrize views and to highlight or exclude data items. We term this information data descriptors, which can span such diverse aspects as the data’s provenance, its storage schema, or its uncertainties. Gathered descriptors encapsulate basic knowledge about the data and can thus be used as objective starting points for the visual analysis process. In this article, we bring together these different aspects in a systematic form that describes the data itself (e.g. its content and context) and its relation to the larger data gathering and visual analysis process (e.g. its provenance and its utility). Once established in general, we further detail the concept of data descriptors specifically for tabular data as the most common form of structured data today. Finally, we utilize these data descriptors for tabular data to capture domain-specific data characteristics in the field of climate impact research. This procedure from the general concept via the concrete data type to the specific application domain effectively provides a blueprint for instantiating data descriptors for other data types and domains in the future.

Repurposing Ruxolitinib in Combating COVID-19: a mini review

2021 ◽  
Vol 02 ◽  
Author(s):  
Inshia Begum ◽  
Fathima Murthuza ◽  
Juwairiya Syed Iqbaluddin ◽  
Hafsah Fatima Arsal
Keyword(s):  
Clinical Trials ◽  
Severity Of Illness ◽  
Current Evidence ◽  
Public Healthcare ◽  
Inclusion Criteria ◽  
Research Papers ◽  
Exclusion Criteria ◽  
Mixed Treatment ◽  
Marked Selectivity ◽  
Insight Into

Background: The pandemic caused by Coronavirus Disease 2019 (COVID-19), also known as Severe Acute Respiratory Syndrome-Related Coronavirus (SARS-CoV-2), is believed to be one of the greatest threats to global health in the 21st century. Recent collective evidence has warranted Ruxolitinib as a potential agent in recovery. Ruxolitinib is a potent and selective inhibitor of Jack kinase (JAK) 1 and 2 with modest to marked selectivity against tyrosine kinase two and JAK3. Objective: The review aims to outline the current evidence regarding the repurposed treatment for COVID- 19 and give insight into the clinical trials. There has been considerable interest in introducing existing therapeutic agents against COVID-19 to reduce the severity of illness and ease the burden on public healthcare systems. Method: A literature search was conducted using keywords like ‘Ruxolitinib trial’ and ‘COVID-19 Ruxolitinib’ on PubMed, Google Scholar, Science Direct, and Cochrane databases to select research papers and articles on the topic published from January to October 2020. Inclusion criteria were restricted to articles on Ruxolitinib and COVID. In contrast, the exclusion criteria stipulated that any study done on COVID-19 involving a mixed treatment regimen with Ruxolitinib and other drug/s or any studies not pertinent to the purpose of the study would be omitted. Conclusion: Based on the successful outcomes of various researches conducted and clinical trials performed, the use of Ruxolitinib has shown significant improvement and faster clinical recovery among COVID-19 patients of varying severity of infection, advanced age, and multiple comorbidities. This review provides an overview of various such studies with their promising outcomes.

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