scholarly journals A Novel Technique to Increase the Thickness of TiO₂ of Dental Implants by Nd: DPSS Q-sw Laser Treatment

Materials ◽  
2020 ◽  
Vol 13 (18) ◽  
pp. 4178
Author(s):  
Antonio Scarano ◽  
Francesca Postiglione ◽  
Ahmad G. A. Khater ◽  
Faez Saleh Al-Hamed ◽  
Felice Lorusso
Keyword(s):  
Oxide Layer ◽  
Laser Treatment ◽  
Dental Implants ◽  
Photoelectron Spectroscopy ◽  
Clinical Success ◽  
Tissue Response ◽  
Implant Surface ◽  
Study Results ◽  
Dental Implant Surface ◽  
High Bone

High bone–implant contact is a crucial factor in the achievement of osseointegration and long time clinical success of dental implants. Micro, nano, microtopography, and oxide layer of dental implants influence tissue response. The lasers were used for achieving an implant surface with homogeneous micro texturing and uncontaminated surface. The present study aimed to characterize the implant surfaces treated by Nd: DPSS Q-sw Laser treatment compared to machined implants. A total of 10 machined implants and 10 lasered surface implants were evaluated in this study. The implant surfaces were evaluated by X-ray Photoelectron Spectroscopy (XPS), Auger Electron Spectroscopy (AES), and metallography to characterize and measure the thickness of the oxide layer on the implant titanium surface. The machined surfaces showed a non-homogeneous oxide layer ranging between 20 and 30 nm. The lasered implant surfaces showed a homogeneous oxide layer ranging between 400 nm and 460 nm in the area of the laser holes, while outside the layer, thickness ranged between 200 nm and 400 nm without microcracks or evidence of damage. Another exciting result after this laser treatment is a topographically controlled, repeatable, homogeneous, and clean surface. This technique can obtain the implant surface without leaving residues of foreign substances on it. The study results indicate that the use of Nd: DPSS Q-sw laser produces a predictable and reproducible treatment able to improve the titanium oxide layer on the dental implant surface.

scholarly journals Antimicrobial Effects of Three Different Treatment Modalities on Dental Implant Surfaces

2017 ◽  
Vol 43 (6) ◽  
pp. 429-436 ◽  
Author(s):  
Olav I. Larsen ◽  
Morten Enersen ◽  
Anne Karin Kristoffersen ◽  
Ann Wennerberg ◽  
Dagmar F. Bunæs ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Er:Yag Laser ◽  
Antimicrobial Effect ◽  
Positive Control ◽  
Treatment Modalities ◽  
Bacterial Strains ◽  
Implant Surface ◽  
Antimicrobial Effects ◽  
Dental Implant Surface

Resolution of peri-implant inflammation and re-osseointegration of peri-implantitis affected dental implants seem to be dependent on bacterial decontamination. The aims of the study were to evaluate the antimicrobial effects of 3 different instrumentations on a micro-textured dental implant surface contaminated with an avirulent or a virulent Porphyromonas gingivalis strain and to determine alterations to the implant surface following instrumentation. Forty-five dental implants (Straumann SLA) were allocated to 3 treatment groups: Er:YAG laser, chitosan brush, and titanium curette (10 implants each) and a positive (10 implants) and a negative (5 implants) control. Each treatment group and the positive control were split into subgroups of 5 implants subsequently contaminated with either the avirulent or virulent P. gingivalis strain. The antimicrobial effect of instrumentation was evaluated using checkerboard DNA–DNA hybridization. Implant surface alterations were determined using a light interferometer. Instrumentation significantly reduced the number of attached P. gingivalis (P < .001) with no significant differences among groups (P = .310). A significant overall higher median score was found for virulent compared with avirulent P. gingivalis strains (P = .007); the Er:YAG laser uniquely effective removing both bacterial strains. The titanium curette significantly altered the implant surface micro-texture. Neither the Er:YAG laser nor the chitosan brush significantly altered the implant surface. The 3 instrumentations appear to have a similar potential to remove P. gingivalis. The titanium curette significantly altered the microstructure of the implant surface.

scholarly journals Preparation of Bioactive Titanium Surfaces via Fluoride and Fibronectin Retention

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Carlos Nelson Elias ◽  
Patricia Abdo Gravina ◽  
Costa e Silva Filho ◽  
Pedro Augusto de Paula Nascente
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Osteoblastic Cells ◽  
Acid Etching ◽  
Implant Surface ◽  
Force Microscopy ◽  
Dental Implant Surface ◽  
Before And After ◽  
Titanium Surfaces

Statement of Problem. The chemical or topographic modification of the dental implant surface can affect bone healing, promote accelerated osteogenesis, and increase bone-implant contact and bonding strength.Objective. In this work, the effects of dental implant surface treatment and fibronectin adsorption on the adhesion of osteoblasts were analyzed.Materials and Methods. Two titanium dental implants (Porous-acid etching and PorousNano-acid etching followed by fluoride ion modification) were characterized by high-resolution scanning electron microscopy, atomic force microscopy, and X-ray diffraction before and after the incorporation of human plasma fibronectin (FN). The objective was to investigate the biofunctionalization of these surfaces and examine their effects on the interaction with osteoblastic cells.Results. The evaluation techniques used showed that the Porous and PorousNano implants have similar microstructural characteristics. Spectrophotometry demonstrated similar levels of fibronectin adsorption on both surfaces (80%). The association indexes of osteoblastic cells in FN-treated samples were significantly higher than those in samples without FN. The radioactivity values associated with the same samples, expressed as counts per minute (cpm), suggested that FN incorporation is an important determinant of thein vitrocytocompatibility of the surfaces.Conclusion. The preparation of bioactive titanium surfaces via fluoride and FN retention proved to be a useful treatment to optimize and to accelerate the osseointegration process for dental implants.

scholarly journals Impact of Dental Implant Surface Modifications on Osseointegration

2016 ◽  
Vol 2016 ◽  
pp. 1-16 ◽  
Author(s):  
Ralf Smeets ◽  
Bernd Stadlinger ◽  
Frank Schwarz ◽  
Benedicta Beck-Broichsitter ◽  
Ole Jung ◽  
...  
Keyword(s):  
Dental Implants ◽  
Survival Rates ◽  
Surface Modifications ◽  
Comprehensive Overview ◽  
Implant Surface ◽  
Oral Rehabilitation ◽  
New Techniques ◽  
Surface Design ◽  
Dental Implant Surface ◽  
Experimental Surface

Objective.The aim of this paper is to review different surface modifications of dental implants and their effect on osseointegration. Common marketed as well as experimental surface modifications are discussed.Discussion.The major challenge for contemporary dental implantologists is to provide oral rehabilitation to patients with healthy bone conditions asking for rapid loading protocols or to patients with quantitatively or qualitatively compromised bone. These charging conditions require advances in implant surface design. The elucidation of bone healing physiology has driven investigators to engineer implant surfaces that closely mimic natural bone characteristics. This paper provides a comprehensive overview of surface modifications that beneficially alter the topography, hydrophilicity, and outer coating of dental implants in order to enhance osseointegration in healthy as well as in compromised bone. In the first part, this paper discusses dental implants that have been successfully used for a number of years focusing on sandblasting, acid-etching, and hydrophilic surface textures. Hereafter, new techniques like Discrete Crystalline Deposition, laser ablation, and surface coatings with proteins, drugs, or growth factors are presented.Conclusion.Major advancements have been made in developing novel surfaces of dental implants. These innovations set the stage for rehabilitating patients with high success and predictable survival rates even in challenging conditions.

scholarly journals Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition

Biology ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 931
Author(s):  
Guya Diletta Marconi ◽  
Luigia Fonticoli ◽  
Ylenia Della Della Rocca ◽  
Thangavelu Soundara Rajan ◽  
Adriano Piattelli ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Dental Implants ◽  
Dental Implant ◽  
Periodontal Ligament ◽  
Implant Surface ◽  
Periodontal Ligament Stem Cells ◽  
Matrix Deposition ◽  
Dental Implant Surface ◽  
The Impact

The major challenge for dentistry is to provide the patient an oral rehabilitation to maintain healthy bone conditions in order to reduce the time for loading protocols. Advancement in implant surface design is necessary to favour and promote the osseointegration process. The surface features of titanium dental implant can promote a relevant influence on the morphology and differentiation ability of mesenchymal stem cells, induction of the osteoblastic genes expression and the release of extracellular matrix (ECM) components. The present study aimed at evaluating the in vitro effects of two different dental implants with titanium surfaces, TEST and CTRL, to culture the human periodontal ligament stem cells (hPDLSCs). Expression of ECM components such as Vimentin, Fibronectin, N-cadherin, Laminin, Focal Adhesion Kinase (FAK) and Integrin beta-1 (ITGB1), and the osteogenic related markers, as runt related transcription factor 2 (RUNX2) and alkaline phosphatase (ALP), were investigated. Human PDLSCs cultured on the TEST implant surface demonstrated a better cell adhesion capability as observed by Scanning Electron Microscopy (SEM) and immunofluorescence analysis. Moreover, immunofluorescence and Western blot experiments showed an over expression of Fibronectin, Laminin, N-cadherin and RUNX2 in hPDLSCs seeded on TEST implant surface. The gene expression study by RT-PCR validated the results obtained in protein assays and exhibited the expression of RUNX2, ALP, Vimentin (VIM), Fibronectin (FN1), N-cadherin (CDH2), Laminin (LAMB1), FAK and ITGB1 in hPDLSCs seeded on TEST surface compared to the CTRL dental implant surface. Understanding the mechanisms of ECM components release and its regulation are essential for developing novel strategies in tissue engineering and regenerative medicine. Our results demonstrated that the impact of treated surfaces of titanium dental implants might increase and accelerate the ECM apposition and provide the starting point to initiate the osseointegration process.

scholarly journals Critical Role of Etching Parameters in the Evolution of Nano Micro SLA Surface on the Ti6Al4V Alloy Dental Implants

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6344
Author(s):  
Pankaj Chauhan ◽  
Veena Koul ◽  
Naresh Bhatnagar
Keyword(s):  
Surface Topography ◽  
Dental Implants ◽  
Dental Implant ◽  
Ti6al4v Alloy ◽  
Alloy Surface ◽  
Acid Etching ◽  
Implant Surface ◽  
Dental Implant Surface ◽  
Etching Parameters ◽  
Cp Ti

The surface of dental implants plays a vital role in early and more predictable osseointegration. SLA (sandblasted large grit and acid-etched) represents the most widely accepted, long-term clinically proven surface. Primarily, dental implants are manufactured by either commercially pure titanium (CP-Ti) or Ti6Al4V ELI alloy. The acid etch behavior of CP-Ti is well known and its effects on the surface microstructure and physicochemical properties have been studied by various researchers in the past. However, there is a lack of studies showing the effect of acid etching parameters on the Ti6Al4V alloy surface. The requirement of the narrow diameter implants necessitates implant manufacturing from alloys due to their high mechanical properties. Hence, it is necessary to have an insight on the behavior of acid etching of the alloy surface as it might be different due to changed compositions and microstructure, which can further influence the osseointegration process. The present research was carried out to study the effect of acid etching parameters on Ti6Al4V ELI alloy surface properties and the optimization of process parameters to produce micro- and nanotopography on the dental implant surface. This study shows that the Ti6Al4V ELI alloy depicts an entirely different surface topography compared to CP-Ti. Moreover, the surface topography of the Ti6Al4V ELI alloy was also different when etching was done at room temperature compared to high temperature, which in turn affected the behavior of the cell on these surfaces. Both microns and nano-level topography were achieved through the optimized parameters of acid etching on Ti6Al4V ELI alloy dental implant surface along with improved roughness, hydrophilicity, and enhanced cytocompatibility.

scholarly journals Surface Immobilization Chemistry of a Laminin-Derived Peptide Affects Keratinocyte Activity

Coatings ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 560 ◽  
Author(s):  
Nicholas G. Fischer ◽  
Jiahe He ◽  
Conrado Aparicio
Keyword(s):  
Biological Activity ◽  
Cell Adhesion ◽  
Click Chemistry ◽  
Dental Implants ◽  
Photoelectron Spectroscopy ◽  
Artificial Saliva ◽  
Specific System ◽  
Implant Surface ◽  
Substrate Peptide ◽  
Peptide Coatings

Many chemical routes have been proposed to immobilize peptides on biomedical device surfaces, and in particular, on dental implants to prevent peri-implantitis. While a number of factors affect peptide immobilization quality, an easily controllable factor is the chemistry used to immobilize peptides. These factors affect peptide chemoselectivity, orientation, etc., and ultimately control biological activity. Using many different physical and chemical routes for peptide coatings, previous research has intensely focused on immobilizing antimicrobial elements on dental implants to reduce infection rates. Alternatively, our strategy here is different and focused on promoting formation of a long-lasting biological seal between the soft tissue and the implant surface through transmembrane, cell adhesion structures called hemidesmosomes. For that purpose, we used a laminin-derived call adhesion peptide. However, the effect of different immobilization chemistries on cell adhesion peptide activity is vastly unexplored but likely critical. Here, we compared the physiochemical properties and biological responses of a hemidesmosome promoting peptide immobilized using silanization and copper-free click chemistry as a model system for cell adhesion peptides. Successful immobilization was confirmed with water contact angle and X-ray photoelectron spectroscopy. Peptide coatings were retained through 73 days of incubation in artificial saliva. Interestingly, the non-chemoselective immobilization route, silanization, resulted in significantly higher proliferation and hemidesmosome formation in oral keratinocytes compared to chemoselective click chemistry. Our results highlight that the most effective immobilization chemistry for optimal peptide activity is dependent on the specific system (substrate/peptide/cell/biological activity) under study. Overall, a better understanding of the effects immobilization chemistries have on cell adhesion peptide activity may lead to more efficacious coatings for biomedical devices.

Modelling of Mechanically Regulated Tissue Formation Around Bone-Interfacing Implants

2000 ◽  
Author(s):  
Craig A. Simmons ◽  
Shaker A. Meguid ◽  
Robert M. Pilliar
Keyword(s):  
Bone Formation ◽  
Bone Tissue ◽  
Dental Implants ◽  
Clinical Success ◽  
Tissue Formation ◽  
Surface Geometry ◽  
Implant Surface ◽  
Number Of Factors

Abstract The clinical success of bone-interfacing orthopaedic and dental implants is dependent on adequate fixation of the implant by mechanical interlock with ingrown bone tissue (i.e., functional osseointegration). The rate and reliability with which osseointegration is achieved are influenced by a number of factors, including the surface geometry of the implant (Thomas and Cook, 1985; Simmons et al., 1999). However, the mechanisms by which implant surface geometry influences initial bone formation remain unresolved. Identifying the factors that allow bone-interfacing implants to osseointegrate more rapidly and reliably should lead to improvements in their use and design.

scholarly journals Current technology for identifying dental implants: a narrative review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Mohammad Ali Saghiri ◽  
Peter Freag ◽  
Amir Fakhrzadeh ◽  
Ali Mohammad Saghiri ◽  
Jessica Eid
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Clinical Importance ◽  
Forensic Identification ◽  
Current Status ◽  
Main Body ◽  
Implant Surface ◽  
Digital Dentistry ◽  
Dental Implant Surface ◽  
Future Direction

Abstract Background This paper outlines the current status and mechanism for identifying dental implants, with emphasis on future direction and updated technology, and covers the existing factors influencing the identification of implant systems. Main body A search was performed on the current methods of identifying dental implants between January 2000 through Feb 2020 using online databases for articles published in English. The search was performed using the Google, Rutgers library, PubMed, MEDLINE databases via OVID using the following keywords: implant types identification by x-ray imaging, forensic identification of dental implant, surface types, threaded, non-threaded, software identification, recent technologies, which evaluated different methods in the identification of dental implants and its clinical importance for the dentist and the patient. Of the 387 articles found in initial search results, 10 met the inclusion criteria set for this review. These 10 studies were directly related to the identification of different implant systems. Many studies have indicated identifying dental implants as problematic due to many confounding factors, and the difficulty in finding the specific parts for the dental implant itself. The contribution of digital dentistry is critical. Factors like increasing number of implant manufacturers, dental tourism, and cost, make it difficult to detect and match dental implants by dentists during the chairside time. Conclusion These factors give rise to the need for a new system to help clinicians in decision making. Artificial intelligence seems to have shown potential to help in this case. However, detailed regulatory mechanisms are still needed for diagnosis and analysis.

scholarly journals Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

2021 ◽  
Vol 8 ◽  
Author(s):  
Jaison Jeevanandam ◽  
Michael K. Danquah ◽  
Sharadwata Pan
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Bone Cells ◽  
Implant Surface ◽  
Implant Materials ◽  
Synthetic Materials ◽  
Dental Implant Surface ◽  
Nanocarbon Materials ◽  
Ionic States ◽  
Physical And Chemical

Dental implants resemble synthetic materials, mainly designed as teeth-mimics to replace the damaged or irregular teeth. Specifically, they are demarcated as a surgical fixture of artificial implant materials, which are placed into the jawbone, and are allowed to be fused with the bone, similar to natural teeth. Dental implants may be categorized into endosteal, subperiosteal, and zygomatic classes, based on the placement of the implant “in the bone” or on top of the jawbone, under the gum tissue. In general, titanium and its alloys have found everyday applications as common, successful dental implant materials. However, these materials may also undergo corrosion and wear, which can lead to degradation into their ionic states, deposition in the surrounding tissues, as well as inflammation. Consequently, nanomaterials are recently introduced as a potential alternative to replace the conventional titanium-based dental implants. However, nanomaterials synthesized via physical and chemical approaches are either costly, non/less biocompatible, or toxic to the bone cells. Hence, biosynthesized nanomaterials, or bionanomaterials, are proposed in recent studies as potential non-toxic dental implant candidates. Further, nanobiomaterials with plant origins, such as nanocelluloses, nanometals, nanopolymers, and nanocarbon materials, are identified to possess enhanced biocompatibility, bioavailability and no/less cytotoxicity with antimicrobial efficacy at low costs and ease of fabrication. In this minireview, we present an outline of recent nanobiomaterials that are extensively investigated for dental implant applications. Additionally, we discuss their action mechanisms, applicability, and significance as dental implants, shortcomings, and future perspectives.

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