Effects of Mullite, Maghemite, and Silver Nanoparticles Incorporated in β-Wollastonite on Tensile Strength, Magnetism, Bioactivity, and Antimicrobial Activity

β-wollastonite (βW) has sparked much interest in bone defect recovery and regeneration. Biomaterial-associated infections and reactions between implants with human cells have become a standard clinical concern. In this study, a green synthesized βW, synthesized from rice husk ash and a calcined limestone precursor, was incorporated with mullite, maghemite, and silver to produce β wollastonite composite (βWMAF) to enhance the tensile strength and antibacterial properties. The addition of mullite to the βWMAF increased the tensile strength compared to βW. In vitro bioactivity, antibacterial efficacy, and physicochemical properties of the β-wollastonite and βWMAF were characterized. βW and βWMAF samples formed apatite spherules when immersed in simulated body fluid (SBF) for 1 day. In conclusion, βWMAF, according to the tensile strength, bioactivity, and antibacterial activity, was observed in this research and appropriate for the reconstruction of cancellous bone defects.

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Synthesis and Characterization of Silver–Strontium (Ag-Sr)-Doped Mesoporous Bioactive Glass Nanoparticles

Gels ◽

10.3390/gels7020034 ◽

2021 ◽

Vol 7 (2) ◽

pp. 34

Author(s):

Shaher Bano ◽

Memoona Akhtar ◽

Muhammad Yasir ◽

Muhammad Salman Maqbool ◽

Akbar Niaz ◽

...

Keyword(s):

Bioactive Glass ◽

Composite Coatings ◽

Antibacterial Properties ◽

Bone Diseases ◽

Osteogenic Potential ◽

Diffusion Method ◽

Charge Composition ◽

In Vitro Bioactivity ◽

Mesoporous Bioactive Glass

Biomedical implants are the need of this era due to the increase in number of accidents and follow-up surgeries. Different types of bone diseases such as osteoarthritis, osteomalacia, bone cancer, etc., are increasing globally. Mesoporous bioactive glass nanoparticles (MBGNs) are used in biomedical devices due to their osteointegration and bioactive properties. In this study, silver (Ag)- and strontium (Sr)-doped mesoporous bioactive glass nanoparticles (Ag-Sr MBGNs) were prepared by a modified Stöber process. In this method, Ag+ and Sr2+ were co-substituted in pure MBGNs to harvest the antibacterial properties of Ag ions, as well as pro-osteogenic potential of Sr2 ions. The effect of the two-ion concentration on morphology, surface charge, composition, antibacterial ability, and in-vitro bioactivity was studied. Scanning electron microscopy (SEM), X-Ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) confirmed the doping of Sr and Ag in MBGNs. SEM and EDX analysis confirmed the spherical morphology and typical composition of MBGNs, respectively. The Ag-Sr MBGNs showed a strong antibacterial effect against Staphylococcus carnosus and Escherichia coli bacteria determined via turbidity and disc diffusion method. Moreover, the synthesized Ag-Sr MBGNs develop apatite-like crystals upon immersion in simulated body fluid (SBF), which suggested that the addition of Sr improved in vitro bioactivity. The Ag-Sr MBGNs synthesized in this study can be used for the preparation of scaffolds or as a filler material in the composite coatings for bone tissue engineering.

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Evaluating the Antimicrobial Activity of Commercially Available Herbal Toothpastes on Microorganisms Associated with Diabetes Mellitus

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1427 ◽

2013 ◽

Vol 14 (5) ◽

pp. 924-929 ◽

Cited By ~ 4

Author(s):

Reena Kulshrestha ◽

J Kranthi ◽

P Krishna Rao ◽

Feroz Jenner ◽

V Abdul Jaleel ◽

...

Keyword(s):

Diabetes Mellitus ◽

Antimicrobial Activity ◽

Dental Health ◽

Antibacterial Properties ◽

Antimicrobial Properties ◽

Test Organism ◽

Diffusion Method ◽

Zone Of Inhibition ◽

Disk Diffusion Method

ABSTRACT Aim The present study was conducted to evaluate the efficacy of commercially available herbal toothpastes against the different periodontopathogens. Materials and methods Six herbal toothpastes that were commonly commercially available were included in the study. Colgate herbal, Babool, Meswak, Neem active, Dabur red toothpastes were tested for the study whereas sterile normal saline was used as control. Antimicrobial efficacies of dentifrices were evaluated against Streptococcus mutans and Actinobacillus actinomycetemcomitans. The antimicrobial properties of dentifrices were tested by measuring the maximum zone of inhibition at 24 hours on the Mueller Hinton Agar media inoculated with microbial strain using disk diffusion method. Each dentifrice was tested at 100% concentration (full strength). Results The study showed that all dentifrices selected for the study were effective against the entire test organism but to varying degree. Neem active tooth paste gave a reading of 25.4 mm as the zone of inhibition which was highest amongst all of the test dentifrices. Colgate Herbal and Meswak dentifrices recorded a larger maximum zone of inhibition, measuring 23 and 22.6 mm respectively, compared to other toothpastes. All other dentifrices showed the zone of inhibition to be between 17 and 19 mm respectively. Conclusion The antibacterial properties of six dentifrices were studied in vitro and concluded that almost all of the dentifrices available commercially had antibacterial properties to some extent to benefit dental health or antiplaque action. How to cite this article Jenner F, Jaleel VA, Kulshrestha R, Maheswar G, Rao PK, Kranthi J. Evaluating the Antimicrobial Activity of Commercially Available Herbal Toothpastes on Microorganisms Associated with Diabetes Mellitus. J Contemp Dent Pract 2013;14(5):924-929.

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The effect of calcinated hydroxyapatite and magnesium doped hydroxyapatite as fillers on the mechanical properties of a model BisGMA/TEGDMA dental composite initially and after aging

Metallurgical and Materials Engineering ◽

10.30544/403 ◽

2018 ◽

Vol 24 (4) ◽

Cited By ~ 2

Author(s):

Tamara Matic ◽

Maja Ležaja Zebić ◽

Ivana Cvijović-Alagić ◽

Vesna Miletić ◽

Rada Petrović ◽

...

Keyword(s):

Mechanical Properties ◽

Body Fluid ◽

Control Sample ◽

Dental Composite ◽

In Vitro Bioactivity ◽

Significant Difference ◽

Nanosized Hydroxyapatite ◽

Glass Fillers ◽

Mg Doped

The aim of this study was to investigate the possibility of modifying model BisGMA/TEGDMA dental composite by substituting 10 wt. % of conventional glass fillers with bioactive fillers based on calcinated nanosized hydroxyapatite (HAp) and Mg doped hydroxyapatite (Mg-HAp). HAp and Mg-HAp powders were synthesized hydrothermally. Mechanical properties: hardness by Vickers (HV) and flexural strength (Fs) were tested initially and after being stored for 28 days in simulated body fluid (SBF). The experimental composites with HAp and Mg-HAp particles showed no statistically significant difference in HV compared to the control (p>0.05) either initially or after storage. Although mean Fs values of modified composites tested initially were lower (62 MPa) than those of the control (72 MPa), after 28 days of storage in SBF Fs values were greater for modified composites (42 MPa control sample, 48 MPa HAp and Mg-HAp samples). In vitro bioactivity of BisGMA/TEGDMA composites with HAp and Mg-HAp particles after 28 days in SBF was not detected. Keywords: hydroxyapatite; magnesium; dental composite; mechanical properties;

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Synthesis of sol-gel derived glass powder and in vitro bioactivity property tested in simulated body fluid

10.1063/1.4966819 ◽

2016 ◽

Author(s):

S. A. Syed Nuzul Fadzli ◽

S. Roslinda ◽

Firuz Zainuddin ◽

Hamisah Ismail

Keyword(s):

Simulated Body Fluid ◽

Body Fluid ◽

Glass Powder ◽

Sol Gel ◽

In Vitro Bioactivity

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In vitro bioactivity, mechanical behavior and antibacterial properties of mesoporous SiO2-CaO-Na2O-P2O5 nano bioactive glass ceramics

Journal of the Mechanical Behavior of Biomedical Materials ◽

10.1016/j.jmbbm.2019.103379 ◽

2019 ◽

Vol 100 ◽

pp. 103379 ◽

Cited By ~ 1

Author(s):

M.S. Kairon Mubina ◽

S. Shailajha ◽

R. Sankaranarayanan ◽

L. Saranya

Keyword(s):

Bioactive Glass ◽

Mechanical Behavior ◽

Antibacterial Properties ◽

Glass Ceramics ◽

In Vitro Bioactivity ◽

Mesoporous Sio2

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In Vitro Bioactivity of Composite of Nanophase Titania/Bioactive Glass-Ceramic in Simulated Body Fluid

Advanced Biomaterials VI - Key Engineering Materials ◽

10.4028/0-87849-967-9.171 ◽

2005 ◽

pp. 171-174

Author(s):

Hui Wang ◽

Bang Cheng Yang ◽

Qi Feng Yu ◽

Dayi Wu ◽

Xing Dong Zhang

Keyword(s):

Simulated Body Fluid ◽

Bioactive Glass ◽

Glass Ceramic ◽

Body Fluid ◽

In Vitro Bioactivity

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Bioactive Composite Materials for Bone Tissue Applications

Materials Science Forum ◽

10.4028/www.scientific.net/msf.514-516.985 ◽

2006 ◽

Vol 514-516 ◽

pp. 985-989

Author(s):

B.J.M. Leite Ferreira ◽

M.G.G.M. Duarte ◽

M. Helena Gil ◽

Rui N. Correia ◽

J. Román ◽

...

Keyword(s):

Electron Microscopy ◽

Bone Tissue ◽

Tissue Repair ◽

Body Fluid ◽

In Vitro Bioactivity ◽

X Ray Diffraction ◽

X Ray ◽

Biodegradable Composite ◽

Scanning Electron

Two materials with potential application in bone tissue repair have been developed: 1) a non-biodegradable composite based in a new methacrylic-co-acrylic matrix; and 2) a biodegradable composite based in a chitosan (Ch) matrix. Both matrices were reinforced with glass-ceramic particles of composition (mol%) 70 SiO2 – 30 CaO. The in vitro bioactivity of composites was assessed by soaking in simulated body fluid (SBF) for periods of up to 7 days at 37º C. X-ray diffraction (XRD) and scanning electron microscopy coupled with X-ray energy dispersive spectroscopy (SEM-EDS) were used for deposit identification after different soaking periods. Calcium phosphate particulate deposits were detected after 3 days of immersion, followed by growth and maturation towards apatite.

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Electrochemical Corrosion and In Vitro Bioactivity of Nano-Grained Biomedical Ti-20Nb-13Zr Alloy in a Simulated Body Fluid

Materials ◽

10.3390/ma11010026 ◽

2017 ◽

Vol 11 (1) ◽

pp. 26 ◽

Cited By ~ 11

Author(s):

Mohamed Hussein ◽

Madhan Kumar ◽

Robin Drew ◽

Nasser Al-Aqeeli

Keyword(s):

Simulated Body Fluid ◽

Body Fluid ◽

Electrochemical Corrosion ◽

In Vitro Bioactivity ◽

13Zr Alloy

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Cytocompatibility and Antibacterial Properties of Capping Materials

The Scientific World JOURNAL ◽

10.1155/2014/181945 ◽

2014 ◽

Vol 2014 ◽

pp. 1-10 ◽

Cited By ~ 30

Author(s):

Claudio Poggio ◽

Carla Renata Arciola ◽

Riccardo Beltrami ◽

Annachiara Monaco ◽

Alberto Dagna ◽

...

Keyword(s):

Antimicrobial Activity ◽

Antibacterial Activity ◽

Antibacterial Properties ◽

Disc Diffusion ◽

Streptococcus Salivarius ◽

Diffusion Test ◽

Streptococcus Sanguis ◽

Agar Disc ◽

Bacterial Growth Inhibition

The aim of this study was to evaluate and compare the antimicrobial activity and cytocompatibility of six different pulp-capping materials: Dycal (Dentsply), Calcicur (Voco), Calcimol LC (Voco), TheraCal LC (Bisco), MTA Angelus (Angelus), and Biodentine (Septodont). To evaluate antimicrobial activity, materials were challengedin vitrowithStreptococcus mutans,Streptococcus salivarius, andStreptococcus sanguisin the agar disc diffusion test. Cytocompatibility of the assayed materials towards rat MDPC-23 cells was evaluated at different times by both MTT and apoptosis assays. Results significantly differed among the different materials tested. Both bacterial growth inhibition halos and cytocompatibility performances were significantly different among materials with different composition. MTA-based products showed lower cytotoxicity and valuable antibacterial activity, different from calcium hydroxide-based materials, which exhibited not only higher antibacterial activity but also higher cytotoxicity.

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