scholarly journals Mycosporine-Like Amino Acids from Marine Resource

Marine Drugs ◽  
2021 ◽  
Vol 19 (1) ◽  
pp. 18
Author(s):  
Félix L. Figueroa
Keyword(s):  
Amino Acids ◽  
Growth Factor ◽  
Natural Resources ◽  
Interdisciplinary Approach ◽  
Chemical Identification ◽  
Special Issue ◽  
Dna Protection ◽  
Marine Resource ◽  
Number Of Publications ◽  
Potential Use

In the last 10 years, a great number of publications (both regular papers and reviews) have been published on the interesting molecules—mycosporine-like amino acids (MAAs). Despite significant advances in the research of MAAs, current overviews in the recent publications involving MAA research still need reporting. The aim of this Special Issue is to join, as an interdisciplinary approach, the photochemical and photobiological aspects, with emphasis on new natural resources to obtain both algae and zooplankton MAAs, advances in methodology of extraction and chemical identification of new MAAs. Finally, this Special Issue reviews the bioactivities of MAAs including UVR screen, antioxidant, immunostimulant, growth factor, DNA protection, inhibition of collagenase, elastase and hyaluronidase, and anti-photoaging, among others, and their potential use as nutracosmeceutic molecules (i.e., oral and topic photoprotector).

Introduction to the Special Issue »Transnational Solidarity – An Interdisciplinary Approach«

2014 ◽  
Vol 52 (1) ◽  
pp. 1
Author(s):  
Stephan Kirste ◽  
Doris Wydra ◽  
Kirsten Schmalenbach ◽  
Sonja Puntscher-Riekmann
Keyword(s):  
Interdisciplinary Approach ◽  
Special Issue ◽  
Transnational Solidarity

scholarly journals Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities.

1988 ◽  
Vol 8 (3) ◽  
pp. 1247-1252 ◽  
Author(s):  
E Lazar ◽  
S Watanabe ◽  
S Dalton ◽  
M B Sporn
Keyword(s):  
Amino Acids ◽  
Biological Activity ◽  
Amino Acid ◽  
Growth Factor ◽  
Aspartic Acid ◽  
Transforming Growth Factor ◽  
Biologically Active ◽  
Single Amino Acid ◽  
Transforming Growth Factor Alpha ◽  
Factor Alpha

To study the relationship between the primary structure of transforming growth factor alpha (TGF-alpha) and some of its functional properties (competition with epidermal growth factor (EGF) for binding to the EGF receptor and induction of anchorage-independent growth), we introduced single amino acid mutations into the sequence for the fully processed, 50-amino-acid human TGF-alpha. The wild-type and mutant proteins were expressed in a vector by using a yeast alpha mating pheromone promoter. Mutations of two amino acids that are conserved in the family of the EGF-like peptides and are located in the carboxy-terminal part of TGF-alpha resulted in different biological effects. When aspartic acid 47 was mutated to alanine or asparagine, biological activity was retained; in contrast, substitutions of this residue with serine or glutamic acid generated mutants with reduced binding and colony-forming capacities. When leucine 48 was mutated to alanine, a complete loss of binding and colony-forming abilities resulted; mutation of leucine 48 to isoleucine or methionine resulted in very low activities. Our data suggest that these two adjacent conserved amino acids in positions 47 and 48 play different roles in defining the structure and/or biological activity of TGF-alpha and that the carboxy terminus of TGF-alpha is involved in interactions with cellular TGF-alpha receptors. The side chain of leucine 48 appears to be crucial either indirectly in determining the biologically active conformation of TGF-alpha or directly in the molecular recognition of TGF-alpha by its receptor.

scholarly journals GC-TOF/MS-based metabolomics analysis to investigate the changes driven by N-Acetylcysteine in the plant-pathogen Xanthomonas citri subsp. citri

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Simone Cristina Picchi ◽  
Mariana de Souza e Silva ◽  
Luiz Leonardo Saldanha ◽  
Henrique Ferreira ◽  
Marco Aurélio Takita ◽  
...  
Keyword(s):  
Amino Acids ◽  
Cell Proliferation ◽  
Plant Pathogen ◽  
Model Organism ◽  
Citrus Canker ◽  
Bacterial Cells ◽  
Xanthomonas Citri ◽  
Canker Disease ◽  
Potential Use

AbstractN-Acetylcysteine (NAC) is an antioxidant, anti-adhesive, and antimicrobial compound. Even though there is much information regarding the role of NAC as an antioxidant and anti-adhesive agent, little is known about its antimicrobial activity. In order to assess its mode of action in bacterial cells, we investigated the metabolic responses triggered by NAC at neutral pH. As a model organism, we chose the Gram-negative plant pathogen Xanthomonas citri subsp. citri (X. citri), the causal agent of citrus canker disease, due to the potential use of NAC as a sustainable molecule against phytopathogens dissemination in citrus cultivated areas. In presence of NAC, cell proliferation was affected after 4 h, but damages to the cell membrane were observed only after 24 h. Targeted metabolite profiling analysis using GC–MS/TOF unravelled that NAC seems to be metabolized by the cells affecting cysteine metabolism. Intriguingly, glutamine, a marker for nitrogen status, was not detected among the cells treated with NAC. The absence of glutamine was followed by a decrease in the levels of the majority of the proteinogenic amino acids, suggesting that the reduced availability of amino acids affect protein synthesis and consequently cell proliferation.

scholarly journals Assessment and Governance of Sustainable Soil Management

2018 ◽  
Vol 10 (12) ◽  
pp. 4432 ◽  
Author(s):  
Katharina Helming ◽  
Katrin Daedlow ◽  
Bernd Hansjürgens ◽  
Thomas Koellner
Keyword(s):  
Driving Forces ◽  
Interdisciplinary Approach ◽  
Soil Management ◽  
Research Field ◽  
Future Research ◽  
Soil Functions ◽  
Special Issue ◽  
Arable Soils ◽  
Sustainable Soil Management ◽  
Production Conditions

The globally increasing demand for food, fiber, and bio-based products interferes with the ability of arable soils to perform their multiple functions and support sustainable development. Sustainable soil management under high production conditions means that soil functions contribute to ecosystem services and biodiversity, natural and economic resources are utilized efficiently, farming remains profitable, and production conditions adhere to ethical and health standards. Research in support of sustainable soil management requires an interdisciplinary approach to three interconnected challenges: (i) understanding the impacts of soil management on soil processes and soil functions; (ii) assessing the sustainability impacts of soil management, taking into account the heterogeneity of geophysical and socioeconomic conditions; and (iii) having a systemic understanding of the driving forces and constraints of farmers’ decision-making on soil management and how governance instruments may, interacting with other driving forces, steer sustainable soil management. The intention of this special issue is to take stock of an emerging interdisciplinary research field addressing the three challenges of sustainable soil management in various geographic settings. In this editorial, we summarize the contributions to the special issue and place them in the context of the state of the art. We conclude with an outline of future research needs.

scholarly journals Gemar Makan Ikan untuk Kecerdasan Anak Sekolah di MTS Al-Maidar Pandan Kabupaten Tapanuli Tengah

2021 ◽  
Vol 6 (3) ◽  
pp. 455-464
Author(s):  
Emma Suri Yanti Siregar ◽  
Tengku Muhammad Ghazali ◽  
Rosmasita Rosmasita ◽  
Dian Fitria ◽  
Juliana Pebrina Siburian ◽  
...  
Keyword(s):  
Amino Acids ◽  
Young People ◽  
Natural Resources ◽  
Protein Content ◽  
Community Service ◽  
Fish Consumption ◽  
Nutritional Value ◽  
Daily Consumption ◽  
High Protein Content ◽  
Service Activity

 Indonesia is a maritime country that has many marine natural resources. Central Tapanuli Regency has a position close to the sea. Even though fish has a high protein content with amino acids, students or young people still like to eat fish a little. So it is necessary to provide information and at the same time invite the younger generation to like to eat fish to increase their intelligence. This community service activity was carried out at MTS Al-Maidar Pandan, Pandan District, Central Tapanuli Regency. The method of implementing this service activity is done by providing socialization about the importance of eating fish for MTS Al Maidar students. The outcomes achieved are increasing students' knowledge about the benefits of fish consumption and the nutritional value contained in fish as well as providing students' understanding with the knowledge to be able to distinguish between fish that are suitable for daily consumption or not.

Sign in / Sign up

Export Citation Format

Share Document