scholarly journals Quality Evaluation of Ophiopogonis Radix from Two Different Producing Areas

Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3220 ◽  
Author(s):  
Mengxia Tan ◽  
Jiali Chen ◽  
Chengcheng Wang ◽  
Lisi Zou ◽  
Shuyu Chen ◽  
...  
Keyword(s):  
Ion Trap ◽  
Comprehensive Evaluation ◽  
Functional Health ◽  
Health Food ◽  
Bioactive Constituents ◽  
Components Analysis ◽  
Grey Relational ◽  
Insight Into

Ophiopogonis Radix, also known as Mai-dong in Chinese, was a commonly used traditional Chinese medicine (TCM) and functional health food. Two products of Ophiopogonis Radix are largely produced in the Sichuan and Zhejiang province, which are called “Chuan maidong (CMD)” and “Zhe maidong (ZMD)” respectively. To distinguish and evaluate the quality of CMD and ZMD, an analytical method based on ultra-fast performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry (UFLC-QTRAP-MS/MS) was established for simultaneous determination of 32 constituents including 4 steroidal saponins, 3 homisoflavonoids, 15 amino acids, and 10 nucleosides in 27 Mai-dong samples from Sichuan and Zhejiang. Furthermore, principal components analysis (PCA), partial least squares discriminant analysis (PLS-DA), t-test, and grey relational analysis (GRA) were applied to discriminate and evaluate the samples from Sichuan and Zhejiang based on the contents of 32 constituents. The results demonstrated that the bioactive constituents in CMD and ZMD were significantly different, and CMD performed better in the quality assessment than ZMD. This study not only provides a basic information for differentiating CMD and ZMD, but offers a new insight into comprehensive evaluation and quality control of Ophiopogonis Radix from two different producing areas.

scholarly journals Comparison of Multiple Bioactive Constituents in the Corolla and Other Parts of Abelmoschus manihot

Molecules ◽  
2021 ◽  
Vol 26 (7) ◽  
pp. 1864
Author(s):  
Shengxin Yin ◽  
Yuqi Mei ◽  
Lifang Wei ◽  
Lisi Zou ◽  
Zhichen Cai ◽  
...  
Keyword(s):  
Ion Trap ◽  
Distribution Patterns ◽  
Scientific Data ◽  
The Other ◽  
Bioactive Constituents ◽  
Medicinal Value ◽  
Components Analysis ◽  
Fast Performance Liquid Chromatography ◽  
Different Parts

Abelmoschus manihot (L.) Medic (AM), called Huangshukui in Chinese, is a widely used medicinal plant. Each part of AM has medicinal value, including Abelmoschi Radix (AR), Abelmoschi Herba (AH), Abelmoschi Folium (AF), Abelmoschi Corolla (AC), and Abelmoschi Semen (AS). However, only AC is documented in the Chinese Pharmacopoeia. In order to investigate whether there is any difference between AC and the other parts of AM, an analytical method based on ultra-fast performance liquid chromatography coupled with triple quadrupole-linear ion trap mass spectrometry (UFLC-QTRAP-MS/MS) was established for the simultaneous determination of 35 constituents in different parts of AM. Moreover, principal components analysis (PCA) and partial least squares discriminant analysis (PLS-DA) were applied to classify and evaluate the different parts of AM based on the content of the 35 constituents. The total contents of the 35 constituents in AC were significantly higher than in the other parts of AM and the results revealed significant differences between AC and the other parts of AM. Eight constituents were remarkably related to the sample classifications. This research does not just provide the basic information for revealing the distribution patterns in different parts of AM from the same origin, but also complements some of the scientific data for the comprehensive quality evaluation of AC.

A rapid and highly sensitive method for simultaneous determination of bioactive constituents in leaf extracts of six Ocimum species using ultra high performance liquid chromatography-hybrid linear ion trap triple quadrupole mass spectrometry

2016 ◽  
Vol 8 (2) ◽  
pp. 333-341 ◽  
Author(s):  
Renu Pandey ◽  
Preeti Chandra ◽  
Brijesh Kumar ◽  
Bhupender Dutt ◽  
Kulwant Rai Sharma
Keyword(s):  
Food Processing ◽  
High Performance ◽  
Ion Trap ◽  
Linear Ion Trap ◽  
Quadrupole Mass ◽  
Bioactive Constituents ◽  
Leaf Extracts ◽  
Highly Sensitive ◽  
Ocimum Species

Ocimum species have tremendous value in pharmaceutical, perfumery, food processing and cosmetic industries, also in traditional rituals and medicines.

scholarly journals Bioactive Micronutrients in Coffee: Recent Analytical Approaches for Characterization and Quantification

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Abdulmumin A. Nuhu
Keyword(s):  
Latin America ◽  
Biological Activities ◽  
Chemical Compounds ◽  
Well Being ◽  
Bioactive Constituents ◽  
Coffee Beans ◽  
Sensory Qualities ◽  
Analytical Approaches

Production of coffee beans is an important lifeline for the economy of several countries in Latin America, Africa, and Asia. The brew from this well sought for cash crop is readily consumed due to its good sensory qualities owing to the presence of many micronutrients. Some of these chemical compounds possess biological activities, including antiproliferative, antioxidant, and antimicrobial effects. Four representative groups of these micronutrients, namely, caffeine, chlorogenic acid, diterpenes, and trigonelline, play key roles in these bioactive effects of coffee. In order to guarantee the quality of coffee products and to protect consumer interest and safeguard their well-being, it is extremely important to employ sensitive and accurate analytical methods in the characterization and quantitative determination of these bioactive constituents. This review aims to present recent applications in this regard.

scholarly journals A New Strategy for Quality Evaluation and Identification of Representative Chemical Components in Polygonum multiflorum Thunb.

2017 ◽  
Vol 2017 ◽  
pp. 1-11 ◽  
Author(s):  
Yun-xia Li ◽  
Xiao-hong Gong ◽  
Mei-chen Liu ◽  
Cheng Peng ◽  
Peng Li ◽  
...  
Keyword(s):  
Quality Evaluation ◽  
Comprehensive Evaluation ◽  
Principal Component ◽  
Chemical Compounds ◽  
Chemical Components ◽  
Health Food ◽  
Polygonum Multiflorum ◽  
New Strategy ◽  
Novel Method

Polygonum multiflorum Thunb. (HSW) is widely used as herb medicine and health food additive. Recently, a series of HSW-induced hepatotoxicities have been reported and many studies have been carried out to investigate it. But contradictory conclusions were drawn that might be caused by the inconsistent quality of market decoction pieces. Therefore, the HSW decoction pieces quality was evaluated with a developed novel method in the paper. 25 batches of raw HSW (RHSW) and 21 batches of processed HSW (PHSW) samples were purchased from different provinces of China. HPLC determination was performed to identify and detect the contents of 16 chemical compounds in herbal material. Fingerprint similarity was analyzed using chromatography information and the results showed that most herbs were in good similarity. Then, a comprehensive evaluation strategy based on principal component analysis with representative quality control indicators was developed to evaluate the quality of HSW samples. And the rationality of the developed method was verified by HCA analysis. The results showed that the herb from Dabashan, Sichuan Province, no matter RHSW or PHSW had the best quality. Different representative components were selected for RHSW or PHSW decoction pieces which might be caused by the chemical reaction during processing. And most PHSW were unqualified according to the requirement of Chinese Pharmacopeia which might take the responsibility for the toxicity of HSW.

scholarly journals Insight into the Way the Content of Biologically Active Compounds in Meadowsweet Inflorescences (Filipendula ulmaria (L.) Maxim.) Is Shaped by Phytosociological Habitats

Molecules ◽  
2021 ◽  
Vol 26 (17) ◽  
pp. 5172
Author(s):  
Kinga Stawarczyk ◽  
Aleksandra Chrupek ◽  
Agnieszka Sękara ◽  
Michał Gostkowski ◽  
Małgorzata Karbarz
Keyword(s):  
Genetic Material ◽  
Biologically Active ◽  
Raw Material ◽  
Total Phenolic ◽  
Filipendula Ulmaria ◽  
Biochemical Compounds ◽  
Active Chemical ◽  
Insight Into

A collection of herbs from the natural environment remains not only a source of raw material but also provides evidence of chemical differentiation of the local populations. This work aimed at performing a phytosociological analysis of seven different stands of meadowsweet (Filipendula ulmaria (L.) Maxim.) occurrence. A determination of total phenolic compounds and salicylates and the antioxidant activity of dried meadowsweet inflorescences (Flos ulmariae) was also performed. Active chemical compounds in F. ulmaria inflorescences were related to chemotype and diversified between investigated populations. Geographical distance and variation in phytosociological locations affected chemical composition in different ways, shaping the content of biochemical compounds crucial for herbal material quality. The obtained results can be a valuable indicator for Nexo and Baligród populations, which are good genetic material for research, breeding, and cultivation due to their biochemical composition, especially with respect to salicylates, as major compounds of determining market quality of Flos ulmariae.

scholarly journals Dynamic Variations in Multiple Bioactive Constituents under Salt Stress Provide Insight into Quality Formation of Licorice

Molecules ◽  
2019 ◽  
Vol 24 (20) ◽  
pp. 3670 ◽  
Author(s):  
Chengcheng Wang ◽  
Lihong Chen ◽  
Zhichen Cai ◽  
Cuihua Chen ◽  
Zixiu Liu ◽  
...  
Keyword(s):  
Great Influence ◽  
Foreign Market ◽  
Bioactive Constituents ◽  
Dynamic Variations ◽  
China Studies ◽  
Fast Liquid Chromatography ◽  
Production Areas ◽  
Insight Into ◽  
Quality Formation

The demand for licorice and its natural product derivatives in domestic and foreign market is considerably huge. The core production areas of licorice are covered with salinity and drought land in northwestern China. Studies have shown that suitable environmental stress can promote the accumulation of glycyrrhizin and liquiritin to improve its quality as medicinal materials. However, there are few reports on other bioactive constituents of licorice, not to mention their dynamic accumulation under stressed conditions. To explore the quality formation of licorice from the perspective of salt influence, a reliable method based on ultra-fast liquid chromatography tandem triple quadrupole mass spectrometry (UFLC–MS/MS) was established for simultaneous determination of sixteen bioactive constituents, including triterpenoids, flavonoids, chalcones and their glycosides. Physiological experiments were performed to investigate salt tolerance of licorice under different salinity treatments. The expressions of crucial genes (bAS and CHS), key enzymes of triterpenoid and flavonoid synthesis, were also tested by qRT-PCR. Our study found that 50 mM NaCl treatment (low stress) was the most favorable to promote the accumulation of bioactive constituents in the long term, without harming the plants. Flavonoid accumulation of non-stressed and low-stressed groups became different in the initial synthesis stage, and glycosyltransferases may have great influence on their downstream synthesis. Furthermore, bAS and CHS also showed higher levels in low-stressed licorice at harvest time. This work provides valuable information on dynamic variations in multiple bioactive constituents in licorice treated by salt and insight into its quality formation under stressed conditions.

Sex Classification is Better with Three-Dimensional Head Structure Than with Image Intensity Information

Perception ◽  
1997 ◽  
Vol 26 (1) ◽  
pp. 75-84 ◽  
Author(s):  
Alice J O'Toole ◽  
Thomas Vetter ◽  
Nikolaus F Troje ◽  
Heinrich H Bülthoff
Keyword(s):  
Three Dimensional ◽  
Salient Feature ◽  
Male And Female ◽  
Face Representation ◽  
Intensity Information ◽  
The Face ◽  
Components Analysis ◽  
Reduced Representations ◽  
Insight Into

The sex of a face is perhaps its most salient feature. A principal components analysis (PCA) was applied separately to the three-dimensional (3-D) structure and graylevel image (GLI) data from laser-scanned human heads. Individual components from both analyses captured information related to the sex of the face. Notably, single projection coefficients characterized complex differences between the 3-D structure of male and female heads and between male and female GLI maps. In a series of simulations, the quality of the information available in the 3-D head versus GLI data for predicting the sex of the face has been compared. The results indicated that the 3-D head data supported more accurate sex classification than the GLI data, across a range of PCA-compressed (dimensionality-reduced) representations of the heads. This kind of dual face representation can give insight into the nature of the information available to humans for categorizing and remembering faces.

Ceramic Grindability Evaluation with PCA Method

2007 ◽  
Vol 329 ◽  
pp. 421-426 ◽  
Author(s):  
Ai Bing Yu ◽  
Yao Chen ◽  
Da Wei Jia ◽  
Xin Li Tian
Keyword(s):  
Principal Components ◽  
Bending Strength ◽  
Comprehensive Evaluation ◽  
Evaluation Model ◽  
Influence Factors ◽  
Sample Matrix ◽  
Pca Method ◽  
Components Analysis ◽  
Mathematical Evaluation

Mathematical evaluation model for ceramic grindability was presented based on principal components analysis (PCA) method. Sample matrix was constituted with influence factors of ceramic grindability. Principal components and weight vectors were determined through calculation of eigenvalues and eigenvectors of correlation matrix, which was deduced from sample matrix. Comprehensive values could be obtained through eigenvectors and weights vectors. Seven ceramics were selected as evaluation example. Material property parameters including hardness, fracture toughness, Young’s modulus and bending strength were selected as influence factors of ceramic grindability.According to the comprehensive evaluation values, grindability rank of seven materials from better to worse was B4C, sintering SiC, high-purity Al2O3, hot-pressed SiC, sintering Si3N4, hot-pressed Si3N4 and Y-TZP. Moreover, the determination of weight vectors could offer reference for other comprehensive evaluation methods. Research results suggest that PCA is a reasonable and available method to determine the rank of ceramic grindability.

scholarly journals FIRST EXPERIENCE WITH THE USE OF ICF CLASSIFICATION TO EVALUATE PATIENTS WITH PROGRESSIVE NEUROLOGICAL DISEASE IN RESEARCH

2020 ◽  
Vol 50 (4) ◽  
pp. 132-136
Author(s):  
Jarmila Siverová ◽  
Radka Bužgová ◽  
Radka Kozáková
Keyword(s):  
Comprehensive Evaluation ◽  
Neurological Diseases ◽  
Functional Health ◽  
International Classification Of Functioning ◽  
Rehabilitation Care ◽  
Self Sufficiency ◽  
High Level ◽  
Lateral Sclerosis

Neurological conditions are associated with a high level of disability, which affects the overall quality of life of patients and their integration in society. As the disease progresses, self-sufficiency and mobility gradually deteriorate. These limitations are made easier by the use of appropriate compensatory aids and the modification of the environment. The sample included a total of 56 patients with neurological diseases—Multiple Sclerosis (41), Parkinson’s disease (14), and Amyotrophic Lateral Sclerosis (1). Women prevailed in the sample, accounting for 73%. The average age of the patients in the sample was 59.4, ranging from 38 to 81 years. Clinical forms of the ICF classification (International Classification of Functioning, Disability and Health) were used to record the information on the functional state of the patients. The most information was obtained from the ICF classification component Restrictions on Activities and Participation. The qualifiers of performance and capacity point out the supportive use of assistance (e.g. adjustment of the environment, compensatory aids) to improve the participation in patient’s life. Through a comprehensive evaluation of the patient's functional health using the ICF classification, we can obtain his/her functional profile. This information can be used when planning the nursing and rehabilitation care.

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