scholarly journals Biological Activity of Some Aromatic Plants and Their Metabolites, with an Emphasis on Health-Promoting Properties

Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2478 ◽  
Author(s):  
Marek Kieliszek ◽  
Amr Edris ◽  
Anna Maria Kot ◽  
Kamil Piwowarek
Keyword(s):  
Biological Activity ◽  
Medicinal Plants ◽  
Essential Oil ◽  
Biological Activities ◽  
Scientific Evidence ◽  
Mechanisms Of Action ◽  
Volatile Fraction ◽  
Aromatic Plants ◽  
Synthetic Drugs ◽  
Health Promoting

The biological activities of four aromatic plants, namely frankincense, myrrh, ginger, and turmeric, were reviewed in the current study. The volatile fraction (essential oil) as well as the nonvolatile fraction of these four plants showed different promising biological activities that are displayed in detail. These activities can include protection from and/or alleviation of some ailment, which is supported with different proposed mechanisms of action. This review aimed to finally help researchers to get a handle on the importance of considering these selected aromatic plants, which have not been thoroughly reviewed before, as a potential adjuvant to classical synthetic drugs to enhance their efficiency. Moreover, the results elicited in this review encourage the consumption of these medicinal plants as an integrated part of the diet to boost the body’s overall health based on scientific evidence.

scholarly journals Insight into the Presence of Stilbenes in Medicinal Plants Traditionally Used in Croatian Folk Medicine

2016 ◽  
Vol 11 (6) ◽  
pp. 1934578X1601100 ◽  
Author(s):  
Ivana Generalić Mekinić ◽  
Danijela Skroza ◽  
Ivica Ljubenkov ◽  
Višnja Katalinić
Keyword(s):  
Biological Activity ◽  
Medicinal Plants ◽  
Biological Activities ◽  
Folk Medicine ◽  
Free Form ◽  
Naturally Occurring ◽  
Derivatives Of ◽  
Insight Into ◽  
Phenolic Extracts

Over the last years, great interest has arisen concerning plant stilbenes, especially resveratrol, which has a whole spectrum of positive biological activities. In this study, we investigated the presence of resveratrol monomers (trans- and cis- form) and naturally occurring derivatives of fraas-resveratrol (piceid, astringin and isorhapontin) in phenolic extracts of twenty medicinal plants traditionally used in Croatian folk medicine. The investigated compounds were present in the samples, in free form or as glucosides, and the highest share was found in immortelle, common yarrow and Lamiaceae plants. The obtained results indicate that biological activity of selected medicinal plants can be related to the presence of this valuable group of phytochemicals.

scholarly journals A Review on the Medicinal and Aromatic Plants Growing in Libya and Their Therapeutic Properties.

2020 ◽  
pp. 327-334 ◽  
Author(s):  
Abdullah F Abogmaza ◽  
Kheri F Keer ◽  
Ayad A Takrizzah ◽  
Esam Bashir Yahya
Keyword(s):  
Medicinal Plants ◽  
Therapeutic Agent ◽  
Biological Activities ◽  
Therapeutic Option ◽  
Food Preservation ◽  
Aromatic Plants ◽  
Medicinal And Aromatic Plants ◽  
Traditional Use ◽  
Therapeutic Properties ◽  
Therapeutic Activities

Plants are a rich source of diverse metabolites that have been traditionally used for thousands of years all over the world, providing safer and inexpensive therapeutic option for millions of people in developing countries including Libya. Many types of medicinal plants growing in Libya possess significantly important curative activities and have been traditionally used for treatment of chronic diseases such as diabetes and cancer, as well as their biological activities such as antibacterial, antifungal, antiparasitic and insecticidal properties, etc. Apart from the therapeutic activities, most of Libyan nation rather to use natural and plant-based materials for their daily activities such as food preservation, food flavoring as well as medicinal usages. This review presents the most important medicinal plants growing in Libya with their traditional usage, medical properties, and compare the reliability of using these plants as therapeutic agents. Presenting the latest works that have been done in term of justification of the traditional use and scientifically proving its ability as therapeutic agent

scholarly journals Mexican Plants and Derivates Compounds as Alternative for Inflammatory and Neuropathic Pain Treatment—A Review

Plants ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 865
Author(s):  
Geovanna N. Quiñonez-Bastidas ◽  
Andrés Navarrete
Keyword(s):  
Neuropathic Pain ◽  
Medicinal Plants ◽  
Adverse Effects ◽  
Pain Treatment ◽  
Scientific Evidence ◽  
Folk Medicine ◽  
Mechanisms Of Action ◽  
Experimental Models ◽  
Convincing Evidence ◽  
Pharmacological Characterization

Despite the availability of many anti-pain drugs, in the form of NSAIDs, steroids, gabapentinoids, opioids, and antidepressants, in this study we address the natural compounds belonging to the group of Mexican medicinal plants or “Mexican folk medicine”, used for pain management in Mexico. Our interest in this subject is due to the growing idea that “natural is harmless” and to the large number of side effects exhibited in pharmacotherapy. The objective of this review was to document the scientific evidence about Mexican medicinal plants and their derivatives used for inflammatory and neuropathic pain treatment, as well as the mechanisms of action implicated in their antinociceptive effects, their possible adverse effects, and the main pharmacological aspects of each plant or compound. Our data review suggested that most studies on Mexican medicinal plants have used inflammatory experimental models for testing. The anti-pain properties exerted by medicinal plants lack adverse effects, and their toxicological assays report that they are safe to consume; therefore, more studies should be performed on preclinical neuropathic pain models. Moreover, there is no convincing evidence about the possible mechanisms of action involved in the anti-pain properties exerted by Mexican plants. Therefore, the isolation and pharmacological characterization of these plant derivatives’ compounds will be important in the design of future preclinical studies.

scholarly journals The Potential Gastrointestinal Health Benefits of Thymus Vulgaris Essential Oil: A Review

2019 ◽  
Vol 12 (04) ◽  
pp. 1793-1799 ◽  
Author(s):  
Abdulaziz Almanea ◽  
Gamal S. Abd El-Aziz ◽  
Mohamed Morsi M. Ahmed
Keyword(s):  
Medicinal Plants ◽  
Essential Oil ◽  
Biological Activities ◽  
Food Additives ◽  
Health Benefits ◽  
Pharmaceutical Preparations ◽  
Flowering Plant ◽  
Thymus Vulgaris ◽  
Potential Health ◽  
Therapeutic Benefits

In recent times, medicinal plants have received great attention worldwide due to their effective pharmacological properties and therapeutic benefits. Numerous chemical compounds extracted from various medicinal plants have manifold biological activities. Thymus vulgaris (TV) is a flowering plant with an aromatic odor that has been broadly applied in conventional medicine, food additives, and phyto-pharmaceutical preparations. It is recognized to have promising therapeutic potential for curing various types of diseases. The essential oil extracted from TV, which contains a high quantity of flavonoids, possess antioxidant and antimicrobial activities. Consequently, it could be utilized as a good source in developing novel natural antioxidants and antibiotics. This review explores some of the potential health benefits of TV essential oil (TVEO) on the gastrointestinal tract.

scholarly journals Application of medicinal plants in several dermatovenerological entities

2019 ◽  
Vol 69 (4) ◽  
pp. 525-531 ◽  
Author(s):  
Željan Maleš ◽  
Daniela Ledić Drvar ◽  
Ivan Duka ◽  
Kristina Žužul
Keyword(s):  
Medicinal Plants ◽  
Skin Diseases ◽  
Scientific Evidence ◽  
Aloe Vera ◽  
Synthetic Drugs ◽  
Medicinal Treatment ◽  
Herbal Medicinal ◽  
Chronic Skin ◽  
Skin Conditions ◽  
Chronic Skin Diseases

Abstract Treatment of skin conditions with medicinal plants has been an ongoing human activity lasting over thousands of years. The use of specific plant species developed regionally, based on local flora. Commonly used medicinal plants for dermatological complaints are: Phlebodium aureum (L.) J. Sm., Ginkgo biloba L., Rosmarinus officinalis L., Panax ginseng C.A.Mey., Allium cepa L., Aloe vera (L.) Burm.f., Capsicum annuum L., Berbe ris aquifolium Pursh, Camellia sinensis (L.) Kuntze, and Podophyllum peltatum L. The demand for complementary therapeutics is an emerging trend due to the awareness of potential side effects that synthetic drugs might cause. More scientific evidence and better documentation are needed before advising dermatologic patients on herbal medicinal treatment. Standardised extracts and formulations with proven clinical efficacy should be developed for this cause. Here provided review entails the use of herbal medicinal products in the treatment of frequent chronic skin diseases, such as vitiligo, alopecia, psoriasis and genital warts.

scholarly journals Phytochemical Constituents, Biological Activities, and Health-Promoting Effects of the Melissa officinalis

2021 ◽  
Vol 2021 ◽  
pp. 1-20
Author(s):  
Javad Sharifi-Rad ◽  
Cristina Quispe ◽  
Jesús Herrera-Bravo ◽  
Muhammad Akram ◽  
Wafa Abbaass ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Quantitative Research ◽  
Biological Activities ◽  
Phenolic Antioxidants ◽  
Special Focus ◽  
Melissa Officinalis ◽  
Beneficial Effects ◽  
Health Promoting

Medicinal plants are being used worldwide for centuries for their beneficial properties. Some of the most popular medicinal plants belong to the Melissa genus, and different health beneficial effects have already been identified for this genus. Among these species, in particular, the Melissa officinalis L. has been reported as having many biological activities, such as antioxidant, antimicrobial, antitumour, antiviral, antiallergic, anti-inflammatory, and also flatulence inhibiting effects. The beneficial properties of the Melissa officinalis, also known as “lemon balm herb”, can be related to the bioactive compounds such as terpenoids, alcohols, rosmarinic acid, and phenolic antioxidants which are present in the plant. In this updated review, the botanical, geographical, nutritional, phytochemical, and traditional medical aspects of M. officinalis have been considered as well as in vitro and in vivo and clinically proven therapeutic properties have been reviewed with a special focus on health-promoting effects and possible perspective nutraceutical applications. To evidence the relevance of this plant in the research and completely assess the context, a literature quantitative research analysis has been performed indicating the great interest towards this plant for its beneficial properties.

scholarly journals EXPLORING THE ANTIPARASITIC ACTIVITY OF MEDICINAL PLANTS

2020 ◽  
Author(s):  
Gehan Fawzy Abdel Raoof ◽  
Ahmed Wael Lethy Mohamed
Keyword(s):  
Medicinal Plants ◽  
Peer Review ◽  
Biological Activities ◽  
Vital Role ◽  
Parasitic Disease ◽  
Medicinal Uses ◽  
Antiparasitic Activity ◽  
Synthetic Drugs ◽  
E Mail ◽  
Antiparasitic Agents

Parasitic disease is one of the most important challenges impacting a large number of people. Worldwide, more than three billion cases of parasitic disease are reported yearly. Due to the resistance of parasite to the synthetic drugs, it is necessary to search for alternative sources. Plants contain different phytoconstituents with different biological activities.  Many previous researches showed that many plants exerted antiparasitic activity due to its secondary metabolites. This review highlights the antiparasitic effects of different medicinal plants and mentions the mode of action of different phytochemicals against parasites. In conclusion, the medicinal plants play a vital role as antiparasitic agents, but further studies are needed to isolate and test the active constituents of the medicinal plants as antiparasitic agents targeting to enter the drug discoveryarea.  Peer Review History: Received 20 July 2020; Revised 11 August; Accepted 26 August, Available online 15 September 2020 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewer(s) detail: Name: Marwa  A. A. Fayed Affiliation: Faculty of Pharmacy, University of Sadat City, Egypt E-mail: [email protected]   Name: Dr. Mahmut Yıldıztekin Affiliation: Muğla Sıtkı Koçman University, Turkey E-mail: [email protected]   Comments of reviewer(s): Similar Articles: A STUDY ON DIFFERENT PLANTS OF APOCYNACEAE FAMILY AND THEIR MEDICINAL USES A REVIEW ON MEDICINAL USES OF DIFFERENT PLANTS OF EUPHORBIACEAE FAMILY

scholarly journals Seasonal Changes in Essential Oil Constituents of Cystoseira compressa: First Report

Molecules ◽  
2021 ◽  
Vol 26 (21) ◽  
pp. 6649
Author(s):  
Ivana Generalić Mekinić ◽  
Martina Čagalj ◽  
Giulia Tabanelli ◽  
Chiara Montanari ◽  
Federica Barbieri ◽  
...  
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Wide Spectrum ◽  
Marine Macroalgae ◽  
Volatile Fraction ◽  
First Report ◽  
Cystoseira Compressa ◽  
Volatile Organic ◽  
Total Oil ◽  
High Share

Marine macroalgae are well known to release a wide spectrum of volatile organic components, the release of which is affected by environmental factors. This paper aimed to identify the essential oil (EO) compounds of the brown algae Cystoseira compressa collected in the Adriatic Sea monthly, from May until August. EOs were isolated by hydrodistillation using a Clavenger-type apparatus and analyzed by gas chromatography coupled with mass spectrometry (GC–MS). One hundred four compounds were identified in the volatile fraction of C. compressa, accounting for 84.37–89.43% of the total oil. Samples from May, June, and July were characterized by a high share of fatty acids (56, 69, and 34% respectively) with palmitic acid being the dominant one, while in the August sample, a high content of alcohols (mainly phytol and oleyl alcohol) was found. Changes in the other minor components, which could be important for the overall aroma and biological activities of the algal samples, have also been noted during the vegetation periods. The results of this paper contribute to studies of algal EOs and present the first report on C. compressa EOs.

Extractives and biological activities of Lamiaceae species growing in Uzbekistan

Holzforschung ◽  
2020 ◽  
Vol 74 (2) ◽  
pp. 96-115 ◽  
Author(s):  
Nilufar Z. Mamadalieva ◽  
Davlat Kh. Akramov ◽  
Stefan Böhmdorfer ◽  
Shahnoz S. Azimova ◽  
Thomas Rosenau
Keyword(s):  
Biological Activity ◽  
Pharmaceutical Industry ◽  
Essential Oils ◽  
Antioxidant Activities ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Modern Medicine ◽  
Aromatic Plants ◽  
Medicinal And Aromatic Plants ◽  
Botanical Description

AbstractPlants of the Lamiaceae family are important ornamental, medicinal and aromatic plants, with many of them producing essential oils that are used in traditional and modern medicine as well as in the pharmaceutical industry. This review summarizes research on selected Lamiaceae species from the Uzbekistan flora with regard to their chemical constituents and biological activity. These plants contain many bioactive compounds, such as ecdysteroids, iridoids, flavonoids, terpenoids, phenolics and alkaloids, exhibiting different antibacterial, antifungal, cytotoxic and antioxidant activities. The botanical description, taxonomy, habitat and ethnopharmacology of the investigated Lamiaceae species that have been used in Uzbek traditional medicine are presented as well, including the local names.

scholarly journals Pistacia lentiscus Hydrosol: Untargeted Metabolomic Analysis and Anti-Inflammatory Activity Mediated by NF-κB and the Citrate Pathway

2020 ◽  
Vol 2020 ◽  
pp. 1-14
Author(s):  
Anna Santarsiero ◽  
Alberto Onzo ◽  
Raffaella Pascale ◽  
Maria Assunta Acquavia ◽  
Marianna Coviello ◽  
...  
Keyword(s):  
Essential Oil ◽  
Biological Activities ◽  
Inflammatory Activity ◽  
Pistacia Lentiscus ◽  
Atp Citrate Lyase ◽  
Citrate Lyase ◽  
Important Health ◽  
Health Promoting ◽  
Anti Inflammatory ◽  
Main Components

Pistacia lentiscus shows a long range of biological activities, and it has been used in traditional medicine for treatment of various kinds of diseases. Moreover, related essential oil keeps important health-promoting properties. However, less is known about P. lentiscus hydrosol, a main by-product of essential oil production, usually used for steam distillation itself or discarded. In this work, by using ultra-high-resolution ESI(+)-FT-ICR mass spectrometry, a direct identification of four main classes of metabolites of P. lentiscus hydrosol (i.e., terpenes, amino acids, peptides, and condensed heterocycles) was obtained. Remarkably, P. lentiscus hydrosol exhibited an anti-inflammatory activity by suppressing the secretion of IL-1β, IL-6, and TNF-α proinflammatory cytokines in lipopolysaccharide- (LPS-) activated primary human monocytes. In LPS-triggered U937 cells, it inhibited NF-κB, a key transcription factor in inflammatory cascade, regulating the expression of both the mitochondrial citrate carrier and the ATP citrate lyase genes. These two main components of the citrate pathway were downregulated by P. lentiscus hydrosol. Therefore, the levels of ROS, NO, and PGE2, the inflammatory mediators downstream the citrate pathway, were reduced. Results shed light on metabolic profile and anti-inflammatory properties of P. lentiscus hydrosol, suggesting its potential as a therapeutic agent.

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