scholarly journals Study of Flebogrif®—A New Tool for Mechanical Sclerotherapy—Effectiveness Assessment Based on Animal Model

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 544
Author(s):  
Zbigniew Rybak ◽  
Maciej Janeczek ◽  
Maciej Dobrzynski ◽  
Marta Wujczyk ◽  
Albert Czerski ◽  
...  

Sclerotherapy is the chemical occlusion of vessels using an intravenous injection of a liquid or foamed sclerosing agent that is used in the therapy of blood and lymphatic vessels malformations in the young, and for spider veins, smaller varicose veins, hemorrhoids and hydroceles in adults. This study aimed to assess the effectiveness of mechanosclerotherapy of venous veins with a new device—Flebogrif®—based on an animal model. The experiment was performed on nine Polish Merino sheep weighing 40–50 kilograms. The animals were anesthetized intravenously. The material was divided into three groups: two experimental (1 and 2) and control (3) group. The first experimental group was treated with the use of Flebogrif® and a sclerosant simultaneously, while only Flebogrif® was used in the second experimental group. Flebogrif® was applied into the lateral saphenous vein of both pelvic limbs. The vessel wall thickness was estimated at four points of the histological image in mm (V1, V2, V3, V4). For one month, the animals were euthanized, and the occlusion rate of the treated veins and changes in the vein wall were determined. Histological slides were analyzed under a light microscope and histometry of the vein wall was performed. The Shapiro–Wilk test and the quantity of the investigated parameter groups allowed for using a non-parametric method at four points to compare thickness measurements (the Mann–Whitney test), with p < 0.05. The Mann–Whitney test indicated statistically significant differences between both experimental groups. The results obtained from morphometrical and histological analysis showed better results in the first experimental group than those of the second experimental group. Finally, statistical analysis revealed significant differences between the both the experimental group and control group in morphological analysis. The achieved results allowed us to conclude that the simultaneous use of Flebogrif® and a sclerosant yielded better results of vein lumen reduction than the use of Flebogrif® alone.

2019 ◽  
Vol 9 (2) ◽  
pp. 151-159
Author(s):  
Nira Gusfika

This study aims to determine the improvement of organizational commitment through interpersonal communication training. The hypothesis of this research is that there is a difference of organizational commitment to employees between before and after being given interpersonal communication training on experimental group, where the level of commitment of employee organization after being given interpersonal communication training is higher than the level of organizational commitment of the employees before being given interpersonal communication training. Second hypothesis, there is difference of posttest organizational commitment level between experiment group and control group, where posttest of organizational commitment in experiment group is higher than control group.The subject of this research is 17 employees at STAI YAPPTI Balaiselasa. Characteristics of the subjects of this study are employees who have levels of organizational commitment and interpersonal communication in the category very low, low and medium. The design used was Pretest-Posttest Control Group, while the data was collected using organizational commitment scale then analyzed using Mann Whitney test to see the difference of score between the experimental group who were given interpersonal communication training with the control group who were not given interpersonal communication training. Furthermore, Wilcoxon test was done for see experimental group scores between before and after interpersonal communication training.Based on Mann Whitney test results found Z = -3.447 (p <0.01), meaning there is a difference in scores between experimental groups who were trained with control groups who were not trained. Based on Wilcoxon test results found there was a difference between organizational commitment score in the experimental group between before and after being given interpersonal communication training with Z = -2,668 (p<0,01).


2017 ◽  
Vol 3 (6) ◽  
pp. 697-701
Author(s):  
Fara Imelda Theresia Patty ◽  
Suhartono Suhartono ◽  
Ngadiyono Ngadiyono ◽  
Mardiyono Mardiyono

Background: The prolonged partus is one of the causes of maternal deaths marked by the slow progress of labor. Induction of labor and caesarean section is a common procedure performed on long-term partus events to end pregnancy. The birth acupressure technique is a complementary method to activate the hormone oxytocin at a certain point to use to soften the cervix and increase contraction.Objective: To examine the effect of acupressure point LI4, SP6 and BL60 on the duration of the first stage of labor and APGAR Score of newborn in primigravida.Methods: This research employed a Quasy experimental study with posttest control group design. It was conducted at the Public Health Center of Trauma and Public Health Center of Palaran Samarinda, East Kalimantan. There were 40 respondents selected using purposive sampling, which 20 respondents assigned in the experiment and control group. The duration of the first stage of labor was assessed using partograph and APGAR Score was assessed using APGAR Score assessment sheets. Mann Whitney test was used for data analysisResults: Findings showed that the duration of the first stage of labor in the experiment group was 187 minutes and in the control group was 307 minutes. Mann Whitney test obtained p-value 0.001 (<0.05), which indicated that there was a statistically significant difference of the duration of the first stage of labor between both groups. However, Mann Whitney test for APGAR score showed p-value 0.114 (>0.05), which indicated that there was no significant difference of APGAR score in the experiment and control group.Conclusion: There was a significant effect of acupressure on the duration of the first stage of labor, but no effect of the APGAR score. Therefore, acupressure may be recommended to shorten the duration of the first stage of delivery in primigravida.


2019 ◽  
Vol 2 (3) ◽  
pp. 62-71
Author(s):  
Herlina Syafrianti ◽  
Bambang Suwarno ◽  
Elfrida .

This research aimed to know the effect of using metacognitive strategy towards student’s reading comprehension. The design was quasi-experimental. The sample consists of 69 students in two classes. The instrument consists of reading test which was tried out. The treatment for the experiment group was metacognitive strategy and for the control group was the strategy that the teacher use in the class. The data were collected through pre-test and post-test. The activity in the classroom during six meetings, two meetings for pre-test and post-test and four meetings for teaching in the classroom. The data was analyzed by The Wilcoxon Test and The Mann-Whitney Test. The Wilcoxon Test for the control group showed that there was no significant difference between pre-test and post-test. The Wilcoxon test for the experiment group showed that there was significant difference between pre-test and post-test. The Mann-Whitney test for pre-test showed that there was no significant difference between experiment and control class. The Mann-Whitney test for post-test showed that there was significant difference between experiment and control class. Finding of the research showed that, there was significant difference between pre-test and post-test for the experiment class and there was significant differece between experiment and control class for post-test result. This result indicated that there was an effect of metacognitive strategy towards student’s reading comprehension


Author(s):  
Dedeh Rohayati ◽  
Lilies Youlia Friatin

The high increase of electronic media supported by internet resulted in accessing all information easily. Concurrently, the requirement of thinking critically intrigued all parties to be involved in the internet environment. This research aimed at investigating whether or not there were significant mean differences of critical thinking ability in writing exposition text between students who were taught by using E-writing method and those who were given traditional method of writing. The study employed quantitative paradigm design with the type of quasi experimental and involved students which was selected purposively and formed into experimental group and control group. The primary data was the result of pre-test and post-test in the form of essays which were scored by the Holistic Critical Thinking Scoring Rubric (HTCR) developed by Facione & Facione (2011). Based on the result of pre-test and post-test, NGain was analyzed through Man Whitney test to find out the significant mean different of students’ critical thinking ability. After being analyzed by using SPSS 23, the Mann Whitney test came up with the accepted hypotheses i.e., there were significant mean differences of critical thinking ability between experiment group and control group, with mean of NGain score for experimental group was higher than control group had. The statistical output of Mann Whitney test obtained implied that students’ critical thinking ability were influenced by E-writing method. The result of the study convinced that E-writing contributed greater improvement in students’ critical thinking ability than the traditional method did. The finding of present study provided evidence for the effectiveness of E-writing in increasing the students’ ability in thinking critically in writing exposition text.


2020 ◽  
Vol 4 (1) ◽  
pp. 29-37
Author(s):  
Ade Lestiani Limaretha ◽  
Mugi Hartoyo ◽  
Syamsul Arif

Background: Stroke is a brain tissues damage caused by blood supply disruption to the brain. Effects that often occurs in stroke patients is weakness in one side of the body, such as the upper extremity. Exercises to stimulate muscle hands strength can be a combination softball handling exercise and ROM. Purpose: This research aims to determine the effect of a combination softball handling exercise and ROM on muscle strength in non haemoragic stroke patients at Roemani Muhammadiyah Semarang Hospital.Methods: Type of research is Quasi Experiment with a non-rondomised control group pre-post test design. There were 32 respondents including in this research using purposive sampling to select the sample. The research data were analyzed using the Wilcoxon Test to determine the effect on the intervention group and control group, then tested using the Mann Whitney test to determine the effectiveness difference between a intervention group and control group.Results: the Wilcoxon Test showed that there was an effect of a combination softball handlingand ROM on muscle strength in non haemoragic stroke patients (p value 0.000), and there was an effect on the control group without intervention (p value 0.003). While the Mann Whitney test showed that the combination group was more effective in increasing the muscle strength p value = 0.001 (0.05).Conclusion: There is the effect of a combination of softball handling exercise and ROM on the strength of the extremity muscles over non haemoragic stroke pastients.


2019 ◽  
Vol 2 (6) ◽  
pp. 347
Author(s):  
Ajeng Nisa ◽  
Yanti Mustika Oktavianti ◽  
Agus Sumitra

Intelligence for young children is very important for themselves and their social development, because if the intelligence of children develops well, it will be easier for them to get along with creating new things. Besides learning media has a very important role in the learning process. Media that can improve mathematical logical intelligence in children, one of them is the dice numbers. Based on observations shows that the logical-mathematical intelligence of students is still low. This study uses a quasi-experimental method using a non-equivalent control group design. Based on the calculation of the experimental class normality test that is 0.044 <0.05, so the data are declared not normally distributed. While in the control class the result is 0.200> 0.05, until the data are declared normally distributed. Therefore, because one class is declared not normally distributed, the data will be processed using the Mann Whitney test. The results of the Mann Whitney test in the experimental and control classes were 0.001 <0.05. So the conclusion is dice media can improve mathematical logical intelligence.Kecerdasan untuk anak usia dini sangat berperan penting bagi dirinya maupun perkembangan sosialnya, karena jika kecerdasan anak berkembang dengan baik maka akan memudahkan mereka bergaul juga menciptakan hal-hal baru. Selain itu media pembelajaran memiliki peranan sangat penting pada  proses belajar. Media yang dapat meningkatkan kecerdasan logis matematis pada anak, salah satunya yaitu dadu angka. Berdasarkan hasil observasi, kecerdasan logis-matematis peserta didik masih tergolong rendah. Penelitian ini memakai metode kuasi eksperimen serta memakai desain kelompok kontrol non-ekuivalen (the nonequivalent control group design). Berdasarkan perhitungan uji normalitas kelas eksperimen yakni 0.044 < 0.05, sehingga data dinyatakan tidak berdistribusi normal. Sedangkan di kelas kontrol hasilnya adalah 0.200 > 0.05, hingga data dinyatakan berdistribusi normal. Oleh sebab itu karena salah satu kelas dinyatakan tidak berdistribusi normal, data akan diolah memakai uji Mann Whitney. Hasil dari postes Mann whitney di kelas eksperimen serta kontrol adalah 0.001 <  0.05. Jadi kesimpulannya media dadu angka dapat meningkatkan kecerdasan logis matematis.


2018 ◽  
Vol 1 (1) ◽  
pp. 12
Author(s):  
Margiyati Margiyati ◽  
Meidiana Dwidiyanti ◽  
Diyan Yuli Wijayanti

Background: Smoking is a habit that causes many health problems. Nicotine substances in cigarettes cause addiction and carbon monoxide inhaled is poisonous. Hypnotherapy using induction hanung technique is an alternative which can be used to change someone’s smoking behaviors. This therapy is performed by giving hypnotic suggestions combined with a massage at acupuncture points of neguan, yintang, and taiyang. Purpose: This study aimed to analyze the effects of hypnotherapy using induction hanung technique on the level of cigarette dependence and carbon monoxide in exhaled breath among active smokers in Kesdam IV/ Diponegoro College of Nursing, Semarang.Methods: The present study employed a true-experimental pretest-posttest control group design. A total of 40 students were recruited as samples and randomly assigned to the intervention group (n=20) and control group (n=20). The intervention in the form of hypnotherapy using induction hanung technique was given for six times in two weeks. The instruments used were Fagerstorm Test for Cigarette Dependence (FTCD) and smokerlyzer. Data were analyzed with the Mann-Whitney test and independent t-test.Results: The results showed a decrease in the score of cigarette dependence level in the intervention group by 1.25 after the intervention was given with pretest mean value of 1.45 (SD=1.132). The result of Mann-Whitney test showed a significant difference in the cigarette dependence score between the intervention and control groups with a pvalue of 0.028. The level of carbon monoxide in the exhaled breath also decreased by 8.80 ppm after the intervention from the pretest mean values of 12.55 (SD=6.669). The independent sample t-test result also showed a significant difference in the carbon monoxide level between the two groups with a p-value of 0.000.Conclusion: The present findings showed that hypnotherapy using induction hanung technique affected the level of cigarette dependence and carbon monoxide in exhaled breath among the active smokers. Based on the findings, this therapy is recommended as an alternative to nursing intervention for the smoking cessation programs.


2013 ◽  
Vol 8 (2) ◽  
Author(s):  
I Komang Yogi Sukmantara ◽  
Aris Doyan ◽  
Gunawan Gunawan

Abstrak: Penelitian ini bertujuan untuk mengembangkan media pembelajaran web intranet fisika dan mengetahui pengaruhnya terhadap penguasaan konsep dan kemampuan pemecahan masalah siswa. Penelitian ini menggunakan desain penelitian dan pengembangan model Borg dan Gall yang dimodifikasi menjadi 3 tahap, yaitu tahap studi pendahuluan, tahap pengembangan media/produk, dan tahap uji coba media/produk. Media pembelajaran web intranet fisika dikembangkan pada materi usaha, energi, dan daya. Kedua kelas dianalisis menggunakan uji perbedaan rata-rata (Uji t atau Uji Mann-Whitney) dan skor gain ternormalisasi (N-gain). Uji Mann-Whitney penguasaan konsep menghasilkan nilai sebesar 0,047 pada taraf kepercayaan 95% yang berarti terdapat perbedaan yang signifikan antara peningkatan penguasaan konsep kelas eksperimen dibandingkan dengan kelas kontrol. Rata-rata N-gain penguasaan konsep kelas eksperimen adalah 53,73% (sedang) sedangkan rata-rata N-gain kelas kontrol adalah  47,16% (sedang). Uji Mann-Whitney kemampuan pemecahan masalah menghasilkan nilai sebesar 0,34 pada taraf kepercayaan 95% yang berarti tidak terdapat perbedaan signifikan antara kemampuan pemecahan masalah kelas eksperimen dengan kelas kontrol. Rata-rata N-gain kelas eksperimen adalah 48,56% (sedang) sedangkan rata-rata N-gain kelas kontrol adalah 48,16% (sedang).Kata kunci: Web Intranet Fisika, Penguasaan Konsep, dan Kemampuan Pemecahan Masalah. Abstract: The research was aimed at developing a learning media of physics intranet web and knowing its impacts to the concept comprehension and problem solving skills. The research used a research design and development model of Borg and Gall which was modified into three stages; those were stage of preliminary study, stage of media/product development, and stage of media/product testing. The learning material of work, energy and power in the experimental group used the physics intranet web, while the control group did not use it. The data from both groups were analyzed using difference of means test (t-test or Mann-Whitney test) and normalized gain score (N-gain). Mann-Whitney test on concept comprehension generated a value of 0,047 at confidence level of 95%, meaning there was a significant difference between the improvement of concept comprehension in the experimental group and that in the control group. The means of N-gain on concept comprehension of the experimental group was 53,73% (medium), while the means of N-gain of the control group was 47,16% (medium). Mann-Whitney test on problem solving skills generated a value of 0,34 at the confidence level of 95%, meaning there was not a significant difference between the problem solving skill in the experimental group and that in the control group.  The means of N-gain of the experimental group was 48,56% (medium), while the means of N-gain of the control group was 48,16% (medium).Key words: Physics Intranet Web, Concept Comprehension and Problem Solving Skills.


2018 ◽  
Vol 2 (2) ◽  
pp. 58-67
Author(s):  
Herlina Syafrianti ◽  
Bambang Suwarno ◽  
Elfrida .

This research aimed to know the effect of using metacognitive strategy towards student’s reading comprehension. The design was quasi-experimental. The sample consists of 69 students in two classes. The instrument consists of reading test which was tried out. The treatment for the experiment group was metacognitive strategy and for the control group was the strategy that the teacher use in the class. The data were collected through pre-test and post-test. The activity in the classroom during six meetings, two meetings for pre-test and post-test and four meetings for teaching in the classroom. The data was analyzed by The Wilcoxon Test and The Mann-Whitney Test. The Wilcoxon Test for the control group showed that there was no significant difference between pre-test and post-test. The Wilcoxon test for the experiment group showed that there was significant difference between pre-test and post-test. The Mann-Whitney test for pre-test showed that there was no significant difference between experiment and control class. The Mann-Whitney test for post-test showed that there was significant difference between experiment and control class. Finding of the research showed that, there was significant difference between pre-test and post-test for the experiment class and there was significant differece between experiment and control class for post-test result. This result indicated that there was an effect of metacognitive strategy towards student’s reading comprehension.


Author(s):  
Endro Tri Susdarwono

The purpose of this study is to discuss the testing using the Mann-Whitney method and the Wilcoxon signaled level for learning perfect cube and cube root. This research is a quantitative study, while the method used is experimental. The quantitative approach used includes the Mann-Whitney test and Wilcoxon's signed rank test. The conclusions of this study are that: 1) for the Mann-Whitney test on the pretest value of the control group and the experimental group it is concluded that before the treatment of two groups, namely control and experiment, had the same ability in mastering the material to the third power and the cube root; 2) For the Mann-Whitney test on the post-test scores of the control group and the experimental group, it is concluded that after the treatment of two groups, namely the control and the experimental group, they have different abilities in mastery of the material in the third power and the cube root; whereas 3) for the Wilcoxon-signed level test on the pretest and posttest scores of the experimental group, it was concluded that there was a difference between the conditions before and after being given treatments on the mastery of the material to the third power and the perfect cube root.


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