scholarly journals Effect of the Combination of Creatine Monohydrate Plus HMB Supplementation on Sports Performance, Body Composition, Markers of Muscle Damage and Hormone Status: A Systematic Review

Nutrients ◽  
2019 ◽  
Vol 11 (10) ◽  
pp. 2528 ◽  
Author(s):  
Julen Fernández-Landa ◽  
Julio Calleja-González ◽  
Patxi León-Guereño ◽  
Alberto Caballero-García ◽  
Alfredo Córdova ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Composition ◽  
Muscle Damage ◽  
Sport Performance ◽  
Fat Free Mass ◽  
Anaerobic Performance ◽  
Sports Performance ◽  
Positive Effects ◽  
Hormone Status ◽  
Exercise Induced

Although there are many studies showing the isolated effect of creatine monohydrate (CrM) and β-hydroxy β-methylbutyrate (HMB), it is not clear what effect they have when they are combined. The main purpose of this systematic review was to determine the efficacy of mixing CrM plus HMB in comparison with their isolated effects on sports performance, body composition, exercise induced markers of muscle damage, and anabolic-catabolic hormones. This systematic review was carried out in accordance with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) statement guidelines and the PICOS model, for the definition of the inclusion criteria. Studies were found by searching PubMed/MEDLINE, Web of Science (WOS), and Scopus electronic databases from inception to July 3rd 2019. Methodological quality and risk of bias were assessed by two authors independently, and disagreements were resolved by third-party evaluation, in accordance with the Cochrane Collaboration Guidelines samples. The literature was examined regarding the effects of the combination of CrM plus HMB on sport performance using several outcome variables (athletic performance, body composition, markers of muscle damage, and hormone status). This systematic review included six articles that investigated the effects of CrM plus HMB on sport performance (two on strength performance, showing improvements in one of them; three on anaerobic performance, presenting enhancements in two of them; and one on aerobic performance, not presenting improvements), body composition (three on body mass, showing improvements in one of them; two on fat free mass, presenting increases in one of them; and two on fat mass, showing decreases in one of them) and markers of muscle damage and hormone status (four on markers of muscle damage and one on anabolic-catabolic hormones, not showing benefits in any of them). In summary, the combination of 3–10 g/day of CrM plus 3 g/day of HMB for 1–6 weeks could produce potential positive effects on sport performance (strength and anaerobic performance) and for 4 weeks on body composition (increasing fat free mass and decreasing fat mass). However, this combination seems to not show positive effects relating to markers of exercise-induced muscle damage and anabolic-catabolic hormones.

scholarly journals Body composition changes in physically active individuals consuming ketogenic diets: a systematic review

2021 ◽  
Vol 18 (1) ◽  
Author(s):  
Julie L. Coleman ◽  
Christopher T. Carrigan ◽  
Lee M. Margolis
Keyword(s):  
Systematic Review ◽  
Body Composition ◽  
Body Mass ◽  
Risk Of Bias ◽  
Fat Free Mass ◽  
Cochrane Library ◽  
Ideal Strength ◽  
Physically Active ◽  
Ketogenic Diets ◽  
Study Intervention

Abstract Background To achieve ideal strength/power to mass ratio, athletes may attempt to lower body mass through reductions in fat mass (FM), while maintaining or increasing fat-free mass (FFM) by manipulating their training regimens and diets. Emerging evidence suggests that consumption of high-fat, ketogenic diets (KD) may be advantageous for reducing body mass and FM, while retaining FFM. Methods A systematic review of the literature was conducted using PubMed and Cochrane Library databases to compare the effects of KD versus control diets (CON) on body mass and composition in physically active populations. Randomized and non-randomized studies were included if participants were healthy (free of chronic disease), physically active men or women age ≥ 18 years consuming KD (< 50 g carbohydrate/d or serum or whole blood β-hydroxybutyrate (βhb) > 0.5 mmol/L) for ≥14 days. Results Thirteen studies (9 parallel and 4 crossover/longitudinal) that met the inclusion criteria were identified. Aggregated results from the 13 identified studies show body mass decreased 2.7 kg in KD and increased 0.3 kg in CON. FM decreased by 2.3 kg in KD and 0.3 kg in CON. FFM decreased by 0.3 kg in KD and increased 0.7 kg in CON. Estimated energy balance based on changes in body composition was − 339 kcal/d in KD and 5 kcal/d in CON. Risk of bias identified some concern of bias primarily due to studies which allowed participants to self-select diet intervention groups, as well as inability to blind participants to the study intervention, and/or longitudinal study design. Conclusion KD can promote mobilization of fat stores to reduce FM while retaining FFM. However, there is variance in results of FFM across studies and some risk-of-bias in the current literature that is discussed in this systematic review.

scholarly journals Maternal obesity and offspring body composition by indirect methods: a systematic review and meta-analysis

2015 ◽  
Vol 31 (10) ◽  
pp. 2073-2092 ◽  
Author(s):  
Helen Castillo-Laura ◽  
Iná S. Santos ◽  
Lenice C. M. Quadros ◽  
Alicia Matijasevich
Keyword(s):  
Systematic Review ◽  
Body Composition ◽  
Body Fat ◽  
Fat Mass ◽  
Maternal Obesity ◽  
Fat Free Mass ◽  
Case Control Studies ◽  
Indirect Methods ◽  
Body Fat Percent ◽  
Maternal Overweight

Abstract This study reviewed the evidence that assessed the association between maternal pre-pregnancy body mass index (BMI) and/or gestational weight gain and offspring body composition in childhood. A systematic review was conducted. Cohort studies, case-control studies and randomized controlled trials measuring offspring body composition by indirect methods were included. Meta-analyses of the effect of pre-pregnancy BMI on offspring fat-free mass, body fat percent, and fat mass were conducted through random-effects models. 20 studies were included, most of which reported a positive association of pre-pregnancy BMI with offspring body fat. Standardized mean differences in body fat percent, fat mass and fat-free mass between infants of women with normal pre-pregnancy BMI and those of overweight/obese women were 0.31 percent points (95%CI: 0.19; 0.42), 0.38kg (95%CI: 0.26; 0.50), and 0.18kg (95%CI: -0.07; 0.42), respectively. Evidence so far suggests that pre-pregnancy maternal overweight is associated with higher offspring adiposity.

scholarly journals Low Body Fat Does Not Influence Recovery after Muscle-Damaging Lower-Limb Plyometrics in Young Male Team Sport Athletes

2020 ◽  
Vol 5 (4) ◽  
pp. 79
Author(s):  
John F. T. Fernandes ◽  
Kevin L. Lamb ◽  
Craig Twist
Keyword(s):  
Body Composition ◽  
Muscle Damage ◽  
Body Fat ◽  
Knee Extensor ◽  
Young Male ◽  
Peak Torque ◽  
Team Sport ◽  
Flight Time ◽  
Fat Free Mass ◽  
Plyometric Exercise

Aim: This study assessed the influence of fat mass to fat-free mass ratio (FM:FFM) on recovery from plyometric exercise. Method: After assessment of body composition, 20 male team sport players (age 20.7 ± 1.1 years; body mass 77.1 ± 11.5 kg) were divided into low- (n = 10; 0.11 ± 0.03) and normal- (n = 10; 0.27 ± 0.09) fat groups based on FM:FFM ratio. Thereafter, participants completed measurements of knee extensor torque at 60 and 240°∙s−1, countermovement jump flight time, plasma creatine kinase (CK) activity and perceived muscle soreness (VAS) before and at 0, 24 and 48 h after 10 × 10 maximal plyometric vertical jumps. Results: Evidence of muscle damage was confirmed by alterations in VAS, peak torque at 60 and 240°∙s−1 and flight time at 0, 24 and 48 h after plyometric exercise (P < 0.05). CK was increased at 0 and 24 h (P < 0.05) but returned to baseline values by 48 h. No time by group effects were observed for any of the dependent variables (P > 0.05). Conclusion: The current findings indicate that while muscle damage was present after plyometric exercise, the magnitude was similar across the two body composition groups. Applied practitioners can allow for a similar recovery time after plyometric exercise in those with low and normal body fat.

Effect of Milk on Team Sport Performance after Exercise-Induced Muscle Damage

2013 ◽  
Vol 45 (8) ◽  
pp. 1585-1592 ◽  
Author(s):  
EMMA COCKBURN ◽  
PHILLIP G. BELL ◽  
EMMA STEVENSON
Keyword(s):  
Muscle Damage ◽  
Team Sport ◽  
Sport Performance ◽  
Exercise Induced

scholarly journals Effects of Curcumin Supplementation on Inflammatory Markers, Muscle Damage, and Sports Performance during Acute Physical Exercise in Sedentary Individuals

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Kelly Aparecida Dias ◽  
Aline Rosignoli da Conceição ◽  
Lívya Alves Oliveira ◽  
Stephanie Michelin Santana Pereira ◽  
Stefany da Silva Paes ◽  
...  
Keyword(s):  
Physical Exercise ◽  
Muscle Damage ◽  
Inflammatory Markers ◽  
Acute Exercise ◽  
Biological Activities ◽  
Muscle Performance ◽  
Sports Performance ◽  
Positive Effects ◽  
Physical Exercises ◽  
Acute Physical Exercise

Exhaustive and acute unusual physical exercise leads to muscle damage. Curcumin has been widely studied due to the variety of its biological activities, attributed to its antioxidant and anti-inflammatory properties. Furthermore, it has shown positive effects on physical exercise practitioners. However, there is no literature consensus on the beneficial effects of curcumin in acute physical activities performed by sedentary individuals. Therefore, we systematically reviewed evidence from clinical trials on the main effects of curcumin supplementation on inflammatory markers, sports performance, and muscle damage during acute physical exercises in these individuals. We searched PubMed/MEDLINE, Scopus, Web of Science, and Embase databases, and only original studies were analyzed according to the PRISMA guidelines. The included studies were limited to supplementation of curcumin during acute exercise. A total of 5 studies were selected. Methodological quality assessments were examined using the SYRCLE’s risk-of-bias tool. Most studies have shown positive effects of curcumin supplementation in sedentary individuals undergoing acute physical exercise. Overall, participants supplemented with curcumin showed less muscle damage, reduced inflammation, and better muscle performance. The studies showed heterogeneous data and exhibited methodological limitations; therefore, further research is necessary to ensure curcumin supplementation benefits during acute and high-intensity physical exercises. Additionally, mechanistic and highly controlled studies are required to improve the quality of the evidence and to elucidate other possible mechanisms. This study is registered with Prospero number CRD42021262718.

scholarly journals Supplementation with the Leucine Metabolite β-hydroxy-β-methylbutyrate (HMB) does not Improve Resistance Exercise-Induced Changes in Body Composition or Strength in Young Subjects: A Systematic Review and Meta-Analysis

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1523 ◽  
Author(s):  
Josephine S. Jakubowski ◽  
Everson A. Nunes ◽  
Filipe J. Teixeira ◽  
Victoria Vescio ◽  
Robert W. Morton ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Composition ◽  
Resistance Exercise ◽  
Body Mass ◽  
Meta Analysis ◽  
Fat Free Mass ◽  
Strength Analysis ◽  
Composition Analysis ◽  
Total Body Mass ◽  
Leucine Metabolite

β-hydroxy-β-methylbutyrate (HMB) is a leucine metabolite that is purported to increase fat-free mass (FFM) gain and performance in response to resistance exercise training (RET). The aim of this systematic review and meta-analysis was to determine the efficacy of HMB supplementation in augmenting FFM and strength gains during RET in young adults. Outcomes investigated were: total body mass (TBM), FFM, fat mass (FM), total single repetition maximum (1RM), bench press (BP) 1RM, and lower body (LwB) 1RM. Databases consulted were: Medical Literature Analysis and Retrieval System Online (Medline), Excerpta Medica database (Embase), The Cumulative Index to Nursing and Allied Health Literature (CINAHL), and SportDiscus. Fourteen studies fit the inclusion criteria; however, 11 were analyzed after data extraction and funnel plot analysis exclusion. A total of 302 participants (18–45 y) were included in body mass and composition analysis, and 248 were included in the strength analysis. A significant effect was found on TBM. However, there were no significant effects for FFM, FM, or strength outcomes. We conclude that HMB produces a small effect on TBM gain, but this effect does not translate into significantly greater increases in FFM, strength or decreases in FM during periods of RET. Our findings do not support the use of HMB aiming at improvement of body composition or strength with RET.

scholarly journals Modulation of Exercise-Induced Muscle Damage, Inflammation, and Oxidative Markers by Curcumin Supplementation in a Physically Active Population: A Systematic Review

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 501 ◽  
Author(s):  
Diego Fernández-Lázaro ◽  
Juan Mielgo-Ayuso ◽  
Jesús Seco Calvo ◽  
Alfredo Córdova Martínez ◽  
Alberto Caballero García ◽  
...  
Keyword(s):  
Physical Activity ◽  
Systematic Review ◽  
Muscle Damage ◽  
Exercise Performance ◽  
Subjective Perception ◽  
Physically Active ◽  
Active Population ◽  
Oxidative Markers ◽  
Anti Inflammatory ◽  
Exercise Induced

Physical activity, particularly high-intensity eccentric muscle contractions, produces exercise-induced muscle damage (EIMD). The breakdown of muscle fibers and the consequent inflammatory responses derived from EIMD affect exercise performance. Curcumin, a natural polyphenol extracted from turmeric, has been shown to have mainly antioxidant and also anti-inflammatory properties. This effect of curcumin could improve EIMD and exercise performance. The main objective of this systematic review was to critically evaluate the effectiveness of curcumin supplementation on EIMD and inflammatory and oxidative markers in a physically active population. A structured search was carried out following Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines in the databases SCOPUS, Web of Science (WOS), and Medline (PubMed) from inception to October 2019. The search included original articles with randomized controlled crossover or parallel design in which the intake of curcumin administered before and/or after exercise was compared with an identical placebo situation. No filters were applied to the type of physical exercise performed, the sex or the age of the participants. Of the 301 articles identified in the search, 11 met the established criteria and were included in this systematic review. The methodological quality of the studies was assessed using the McMaster Critical Review Form. The use of curcumin reduces the subjective perception of the intensity of muscle pain; reduces muscle damage through the decrease of creatine kinase (CK); increases muscle performance; has an anti-inflammatory effect by modulating the pro-inflammatory cytokines, such as TNF-α, IL-6, and IL-8; and may have a slight antioxidant effect. In summary, the administration of curcumin at a dose between 150–1500 mg/day before and during exercise, and up until 72 h’ post-exercise, improved performance by reducing EIMD and modulating the inflammation caused by physical activity. In addition, humans appear to be able to tolerate high doses of curcumin without significant side-effects.

scholarly journals Cryotherapy Models and Timing-Sequence Recovery of Exercise-Induced Muscle Damage in Middle- and Long-Distance Runners

2020 ◽  
Vol 55 (4) ◽  
pp. 329-335
Author(s):  
Chaoyi Qu ◽  
Zhaozhao Wu ◽  
Minxiao Xu ◽  
Fei Qin ◽  
Yanan Dong ◽  
...  
Keyword(s):  
Muscle Damage ◽  
Cold Water ◽  
Water Immersion ◽  
Whole Body ◽  
Strenuous Exercise ◽  
Distance Runners ◽  
Long Distance ◽  
Positive Effects ◽  
Exercise Induced ◽  
Recovery Methods

Context Among sports-recovery methods, cold-water immersion (CWI), contrast-water therapy (CWT), and whole-body cryotherapy (WBC) have been applied widely to enhance recovery after strenuous exercise. However, the different timing effects in exercise-induced muscle damage (EIMD) after these recovery protocols remain unknown. Objective To compare the effects of CWI, CWT, and WBC on the timing-sequence recovery of EIMD through different indicator responses. Design Crossover study. Setting Laboratory. Patients or Other Participants Twelve male middle- and long-distance runners from the Beijing Sport University (age = 21.00 ± 0.95 years). Intervention(s) Participants were treated with different recovery methods (control [CON], CWI, CWT, WBC) immediately postexercise and at 24, 48, and 72 hours postexercise. Main Outcome Measure(s) We measured perceived sensation using a visual analog scale (VAS), plasma creatine kinase (CK) activity, plasma C-reactive protein (CRP) activity, and vertical-jump height (VJH) pre-exercise, immediately postexercise, and at 1, 24, 48, 72, and 96 hours postexercise. Results For the VAS score and CK activity, WBC exhibited better timing-sequence recovery effects than CON and CWI (P &lt; .05), but the CWT demonstrated better effects than CON (P &lt; .05). The CRP activity was lower after WBC than after the other interventions (P &lt; .05). The VJH was lower after WBC than after CON and CWI (P &lt; .05). Conclusions The WBC positively affected VAS, CK, CRP, and VJH associated with EIMD. The CWT and CWI also showed positive effects. However, for the activity and timing-sequence effect, CWT had weaker effects than WBC.

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