scholarly journals The Effects of Different Quantities and Qualities of Protein Intake in People with Diabetes Mellitus

Nutrients ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 365 ◽  
Author(s):  
Andreas F.H. Pfeiffer ◽  
Eva Pedersen ◽  
Ursula Schwab ◽  
Ulf Risérus ◽  
Anne-Marie Aas ◽  
...  
Keyword(s):  
Body Weight ◽  
Protein Intake ◽  
Fasting Blood Glucose ◽  
Plant Protein ◽  
Metabolic Effects ◽  
Diabetic Patients ◽  
Stable Conditions ◽  
Lower Protein ◽  
Protein Diets

The recommended amount and quality of protein in diets of diabetic patients are highly controversial. In order to provide evidence-based information, the Diabetes Nutrition Study Group (DNSG) used a grading procedure used for quality of evidence and strength of recommendations (GRADE). A protein intake of 10% to 20% of energy intake (E%) or about 0.8 to 1.3 g/kg body weight in people below 65 years of age, and 15% to 20% of E% in people above 65 years of age appeared safe in weight-stable conditions. There were no intervention studies addressing metabolic effects, mortality, or cardiovascular events over prolonged periods. Body weight is closely linked to metabolic control and high protein diets are often recommended. Weight-loss diets that include 23% to 32% of E% as protein for up to one year reduced blood pressure and body weight slightly but significantly more than lower protein diets, whereas blood lipids, fasting blood glucose, and HbA1c improved similarly with higher or lower protein intakes in participants with a glomerular filtration rate (GFR) >60 mL/min/1.73 m2. Patients with a GFR <60 mL/min/1.73 m2 did not show a faster decline of GFR or kidney function with protein intakes around 0.8 g/kg body weight as compared with lower intakes, thereby arguing against a restriction. The effects of protein intake on diabetic eye or nerve disease have not been reported. There are a number of studies that have compared different types of animal proteins (milk, chicken, beef, pork, and fish) or compared animal with plant protein in diabetic patients and have reported a greater reduction of serum cholesterol with plant protein. In summary, the suggested range of protein intake appears to be safe and can be adapted according to personal dietary preferences.

scholarly journals A Comprehensive Review Evaluating the Impact of Protein Source (Vegetarian vs. Meat Based) in Hepatic Encephalopathy

Nutrients ◽  
2021 ◽  
Vol 13 (2) ◽  
pp. 370
Author(s):  
Umair Iqbal ◽  
Ravirajsinh N. Jadeja ◽  
Harshit S. Khara ◽  
Sandeep Khurana
Keyword(s):  
Hepatic Encephalopathy ◽  
Protein Intake ◽  
Alternative Therapy ◽  
Case Series ◽  
Current Evidence ◽  
Branch Chain Amino ◽  
The Impact ◽  
Protein Diets

Hepatic encephalopathy (HE) is a common neurological consequence in patients with cirrhosis and has a healthcare burden of USD 5370 to 50,120 per patient annually. HE significantly hampers the quality of life and is a major cause of morbidity and mortality. Patients with cirrhosis are at a high risk for protein-calorie malnutrition due to altered metabolism. Current evidence has changed the old belief of protein restriction in patients with cirrhosis and now 1.2 to 1.5 g/kg/day protein intake is recommended. Case series and studies with small numbers of participants showed that a vegetarian protein diet decreases the symptoms of HE when compared to a meat-based diet, but the evidence is limited and requires further larger randomized controlled trials. However, vegetable or milk-based protein diets are good substitutes for patients averse to meat intake. Branch chain amino acids (BCAA) (leucine, isoleucine and valine) have also been shown to be effective in alleviating symptoms of HE and are recommended as an alternative therapy in patients with cirrhosis for the treatment of HE. In this review, we provide an overview of current literature evaluating the role of protein intake in the management of HE in cirrhosis.

The Effect of Biochanin A as PPAR γ agonist on LDL Particles Diameter and Type 2 Diabetic Dyslipidemia

2019 ◽  
Author(s):  
Darya Ghadimi ◽  
Mohammad Taghi Taghi Goodarzi ◽  
Mahdi Bahmani ◽  
Zohre Khajehahmadi
Keyword(s):  
Diabetes Mellitus ◽  
Body Weight ◽  
Blood Glucose ◽  
Fasting Blood Glucose ◽  
Male Rats ◽  
Biochanin A ◽  
Diabetic Patients ◽  
Low Density ◽  
Diabetic Dyslipidemia ◽  
Ldl Particles

Background and Aims: Small dense  low-density lipoproteins (sd-LDL) particles are smaller and heavier than typical LDL ones. They can penetrate into the endothelium of coronary arteries more easily because of their small size. Diabetes mellitus is accompanied by dyslipidemia such as increasing concentration of plasma very low density lipoprotein and sd-LDL. Peroxisome proliferator activated receptor γ (PPARγ ) can decrease the level of sd-LDL in plasma. Biochanin A (BCA), a natural compound, is a PPARγ agonist. The present study was designed to investigate the effect of BCA on sd-LDL-Clolesterol level in diabetic animals. Materials and Methods: Adult male rats (Wistar strain) were used as the animal models in this study. Animals were made diabetic by single intraperitoneal injection of Streptozotocin- Nicotinamide and then treated by 1 and 5 mg/kg of BCA for 28 days. Body weight and fasting blood glucose were also tested before and at the end of treatment. Furthermore, the size of LDL particles were measured by nondenaturing polyacrylamide gradient gel electrophoresis assay. Results: Results of the present study indicated that BCA administration at dose of 5mg/kg decreased fasting blood glucose level and increased body weight and diameter of LDL particles in diabetic animals significantly. Conclusions: BCA seems to be an appropriate agent in diabetes mellitus, because it improves the diabetic dyslipidemia, which is the most important complication in diabetic patients.

scholarly journals Association between Low Protein Intake and Mortality in Patients with Type 2 Diabetes

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1629 ◽  
Author(s):  
Takuya Yamaoka ◽  
Atsushi Araki ◽  
Yoshiaki Tamura ◽  
Shiro Tanaka ◽  
Kazuya Fujihara ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Body Weight ◽  
Total Energy ◽  
Energy Intake ◽  
Protein Intake ◽  
Total Energy Intake ◽  
Diabetic Patients ◽  
Low Protein ◽  
Prospective Longitudinal

The aim of this study was to investigate the association between protein intake and mortality risk in patients with type 2 diabetes. We analyzed a pooled data of 2494 diabetic patients from two prospective longitudinal studies. Nutritional intake was assessed using a Food Frequency Questionnaire at baseline. Protein intake per body weight (kg) per day was categorized into quartile groups. Adjusted hazard ratios (HRs) and 95% confidence interval (CI) were calculated using Cox regression analysis. During the six-year follow-up, there were 152 incidents of all-cause mortality. The HR for mortality in the lowest quartile of protein intake per body weight compared with the highest quartile was 2.26 (95% CI: 1.34–3.82, p = 0.002) after adjustment for covariates. Subgroup analyses revealed significant associations between low protein intake and mortality in patients aged over 75 years or under 65 years. After further adjustment of the total energy intake, a significant association between protein intake and mortality remained in patients aged ≥ 75 years, whereas the association was attenuated in those aged < 65 years. Our results suggest that adequate protein intake is necessary in older diabetic patients over 75 years, whereas with diabetes, whereas whole optimal total energy intake is required in younger patients with type 2 diabetes.

scholarly journals Dietary Animal to Plant Protein Ratio Is Associated with Risk Factors of Metabolic Syndrome in Participants of the AHS-2 Calibration Study

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4296
Author(s):  
Bahar Azemati ◽  
Sujatha Rajaram ◽  
Karen Jaceldo-Siegl ◽  
Ella H. Haddad ◽  
David Shavlik ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Dietary Protein ◽  
Protein Intake ◽  
Fasting Blood Glucose ◽  
Plant Protein ◽  
Protein Ratio ◽  
Calibration Study

Background: Few research studies have focused on the effects of dietary protein on metabolic syndrome and its components. Our objective was to determine the relationship between the type of dietary protein intake and animal to plant (AP) protein ratio with metabolic syndrome and its components. Methods: This population-based study had a cross sectional design and conducted on 518 participants of the Adventist Health Study 2 (AHS-2) Calibration Study. Two sets of three dietary 24-h recalls were obtained six months apart. Anthropometric measures and biochemical tests were performed in clinics. Regression calibration models were used to determine the association of type of dietary protein with metabolic syndrome and its components (raised triglyceride, raised blood pressure, reduced high-density lipoprotein cholesterol (HDL), raised fasting blood glucose and increased waist circumference). Results: The likelihood of metabolic syndrome was lower in those with higher total dietary protein and animal protein intake (p = 0.02).Total protein (β = 0.004, [95%CI: 0.002, 0.007]), animal protein intake (β = 0.004, [95%CI: 0.001, 0.007]) and AP protein intake ratio (β = 0.034, [95%CI: 0.021, 0.047]) were positively associated with waist circumference. Higher AP protein ratio was related to higher fasting blood glucose (β = 0.023, [95%CI: 0.005, 0.041]). Conclusion: Our study suggests that considering a significant amount of plant protein as a part of total dietary protein has beneficial effects on cardiometabolic risk factors.

scholarly journals Relationship between animal protein intake and muscle mass index in healthy women

2009 ◽  
Vol 102 (12) ◽  
pp. 1803-1810 ◽  
Author(s):  
Mylène Aubertin-Leheudre ◽  
Herman Adlercreutz
Keyword(s):  
Body Weight ◽  
Muscle Mass ◽  
Protein Intake ◽  
Vegetarian Diet ◽  
Cross Sectional Study ◽  
Animal Protein ◽  
Plant Protein ◽  
Sex Hormone Binding Globulin ◽  
Cross Sectional ◽  
Intake Ratio

The amount and the type of dietary protein could play a role in determining the quantity of skeletal muscle mass. The aim was to examine the relationship between the type of protein intake and the level of muscle mass in healthy omnivorous and vegetarian Caucasian women. The design of the present study was an observational and cross-sectional study. Twenty-one omnivores (Om) and nineteen vegetarians (Ve) were recruited. Muscle mass index (urinary creatinine), dietary intake (5 d dietary records) and biochemical analyses (hormone, phyto-oestrogen and lipid profiles) were obtained. We found differences between groups for muscle mass (Ve: 18 kg v. Om: 23 kg; P = 0·010), muscle mass index (Ve: 6·7 kg/m2v. Om: 8·3 kg/m2; P = 0·002), animal protein intake in g/d (P = 0·001) and in g/kg body weight per d (P = 0·003), plant protein intake in g/d (P = 0·015) and in g/kg body weight per d (P = 0·007), the animal:plant protein intake ratio (P = 0·001) and sex hormone-binding globulin (SHBG) (P = 0·001). Muscle mass index still correlated with animal protein intake in g/d (P = 0·001) and in g/kg body weight per d (P = 0·008), and the animal:plant protein intake ratio (P = 0·007) even after controlling for SHBG and plant protein intake. Finally, animal protein intake (g/d) was the independent predictor of muscle mass index (adjusted r2 0·42). Thus, a vegetarian diet is associated with a lower muscle mass index than is an omnivorous diet at the same protein intake. A good indicator of muscle mass index in women seems to be animal protein intake.

scholarly journals Welfare and quality of farmed trout fed high plant protein diets. 2 innovative killing method effect on stress and quality indicators

2007 ◽  
Vol 6 (sup1) ◽  
pp. 805-805
Author(s):  
M. Mecatti ◽  
G. Parisi ◽  
P. Lupi ◽  
G. Zampacavallo ◽  
G. Giorgi ◽  
...  
Keyword(s):  
Quality Indicators ◽  
Plant Protein ◽  
Method Effect ◽  
Protein Diets

scholarly journals Carcass and meat quality of primiparous sows as related to the lactation period of 21 or 28 days and to body weight loss

2012 ◽  
Vol 81 (3) ◽  
pp. 257-262
Author(s):  
Jolanta Kapelanska ◽  
Salomea Grajewska ◽  
Maria Bocian ◽  
Hanna Jankowiak ◽  
Wojciech Kapelanski
Keyword(s):  
Weight Loss ◽  
Body Weight ◽  
Meat Quality ◽  
Body Weight Loss ◽  
Carcass Quality ◽  
Lactation Period ◽  
Weight Losses ◽  
Lower Protein ◽  
Water Holding

The study included 70 primiparous sows nursing piglets for 21 days and 30 sows nursing piglets for 28 days. Body weight of the sows was recorded at mating, farrowing, weaning and slaughter. The assessment covered the degree of sow body weight loss and its influence on carcass and meat quality as related to the lactation period and to the extent of lactation body loss below 5%, from 5 to 10% and over 10% of body weight. Carcass quality as well as physicochemical meat traits were also subjected to evaluation. Extending the nursing period from 21 to 28 days increased the average lactation body weight loss from 7.88 to 8.50% (P ≤ 0.01). This did not influence the carcass quality in any noticeable way; nonetheless, some meat traits did yield less favourable results. These were related to the electric conductivity of the meat as well as its water holding capacity and colour (P ≤ 0.01). The same undesirable tendency was observed in the group of sows with body weight losses exceeding 10%. It resulted in the decrease of backfat thickness (P ≤ 0.01) and reduction of certain meat traits, particularly lower protein content (P ≤ 0.05). Lower carcass fatness of primiparous sows is a beneficial trait in preparation of a heavy pig for slaughter.

scholarly journals An examination of contributions of animal- and plant-based dietary patterns on the nutrient quality of diets of adult Canadians

2021 ◽  
Author(s):  
Hrvoje Fabek ◽  
Diana Sanchez-Hernandez ◽  
Mavra Ahmed ◽  
Christopher P.F. Marinangeli ◽  
James D House ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Dietary Patterns ◽  
Dietary Fibre ◽  
Protein Intake ◽  
Saturated Fat ◽  
Plant Protein ◽  
Nutrient Intakes ◽  
Nutrient Quality ◽  
Group 1

Dietary guidance and Canada’s 2019 Food Guide encourage increased consumption of plant-based foods as a source of dietary protein. However, there is an absence of recent data on protein and nutrient intakes and quality of Canadian dietary patterns that might occur with increased plant protein intakes. This study compared food sources and nutrient intakes of Canadian adults within groups of increasing plant protein-containing diets. The CCHS 2015 Public-Use Microdata File of single 24-hour dietary recalls of males and females >19 years (n = 6,498) or >70 years (n=1,482) were examined. Respondents were allocated into four groups defined by their protein intake percentage coming from plant-based foods (i.e., Group 1: 0 – 24.9%, Group 2: 25 – 49.9%, Group 3: 50 – 74.9%, Group 4: 75 – 100%). Protein intake in adults averaged 63.3% animal and 36.7% plant protein. Where plant protein contributed >50% protein, higher intakes of carbohydrate, dietary fibre, folate, dietary folate equivalents (DFE), iron and magnesium (p<0.001) but lower intakes of total and saturated fat, protein, vitamin D, vitamin B12, riboflavin and niacin (p<0.0001) were reported. In contrast, Group 1 had higher total and saturated fat, protein, vitamin B12, thiamin, niacin, and zinc, but lower carbohydrate, dietary fibre, and magnesium. Balancing plant- with animal-based protein foods leads to healthier dietary patterns with more favourable nutritional properties when compared to diets based on either high animal or high plant protein content. Novelty bullets: • Combinations of animal- and plant-based proteins improve nutrient quality of Canadian diets. • The source of protein influences diet quality.

scholarly journals Welfare and quality of farmed trout fed high plant protein diets. 3 alternative indicators to evaluate stress in fish

2007 ◽  
Vol 6 (sup1) ◽  
pp. 789-789 ◽  
Author(s):  
D. Bertotto ◽  
C. Poltronieri ◽  
G. Radaelli ◽  
E. Negrato ◽  
B. M. Poli ◽  
...  
Keyword(s):  
Plant Protein ◽  
Protein Diets

scholarly journals Effect of Ramadan Fasting on Anthropometric Measures and Metabolic Profiles among Type 2 Diabetic Subjects

2015 ◽  
Vol 5 (2) ◽  
pp. 93-98 ◽  
Author(s):  
Ajit Kumar Paul ◽  
Murshed Ahamed Khan ◽  
Md Fariduddin
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Serum Creatinine ◽  
Fasting Glucose ◽  
Fasting Blood Glucose ◽  
Diabetic Patients ◽  
Ramadan Fasting ◽  
The Impact ◽  
Type 2 Diabetic

Background: Fasting from dawn to dusk during the month of Holy Ramadan is obligatory for all healthy adult Muslims. Individuals are exempted from fasting if they are suffering from an illness that could be adversely affected by fasting. Although The Quran exempts sick people from fasting, many Muslim diabetic patients may not perceive themselves as sick and are keenly interested to fast. But they fast without proper medical guidance exposing themselves to certain risks as a direct consequence of fasting. So we designed this study to assess the impact of fasting during Ramadan and to evaluate the effects of fasting on their biochemical profiles in patients with diabetes.Objective: The objective of this study was to investigate whether Ramadan fasting has any effect on body weight, blood pressure, fasting glucose, HbA1C, serum lipids, serum creatinine among type 2 diabetic patients.Materials and Methods: Fifty two stable outpatients with type 2 diabetes with intention to fast were studied in the month of Ramadan 1434 Hijri calendar year (11th July to 9th August, 2013) at two points of time: one week before Ramadan (visit 1) and within last 3 days before the end of Ramadan (visit 2). During each visit the height, body weight and blood pressure were recorded. Blood samples were collected for fasting glucose, HbA1C, total cholesterol, triglyceride, high density and low density lipoprotein cholesterol and creatinine. Data were analyzed by Student’s paired t-test using SPSS system and results were expressed as mean ± SD. Probability values were considered to be significant if it was less than 0.05.Results: There were 30 (62.8%) males and 22 (37.2%) females with a mean age of 54.7 ± 11.55 (range 35–80) years and mean duration of diabetes was 5.5 ± 5.2 years (range 9 months–18 years). In this study mean weight of the patients decreased significantly from 60.5 ± 12.6 kg to 58.5 ± 11.3 kg (p<0.001). Blood pressure reduced but not significantly. Fasting blood glucose showed significant reduction from 10.7 ± 4.2 to 8.9 ± 3.7 mmol/L (p=0.002) at the end of the study though HbA1C showed no significant change. Lipid profile and serum creatinine values did not show any significant change.Conclusion: The effects of fasting during Ramadan on stable diabetic patients are minimal. So, stable diabetic patients can fast during Ramadan without significant detrimental effects.J Enam Med Col 2015; 5(2): 93-98

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