scholarly journals Cytocompatibility of Polymethyl Methacrylate Honeycomb-like Pattern on Perfluorinated Polymer

Polymers ◽  
2021 ◽  
Vol 13 (21) ◽  
pp. 3663
Author(s):  
Klaudia Hurtuková ◽  
Veronika Juřicová ◽  
Klára Fajstavrová ◽  
Dominik Fajstavr ◽  
Nikola Slepičková Kasálková ◽  
...  

In this study, we present a simple approach for developing a biocompatible polymer scaffold with a honeycomb-like micropattern. We aimed to combine a plasma treatment of fluorinated ethylene propylene (FEP) substrate with an improved phase separation technique. The plasma exposure served for modification of the polymer surface properties, such as roughness, surface chemistry, and wettability. The treated FEP substrate was applied for the growth of a honeycomb-like pattern from a solution of polymethyl methacrylate (PMMA). The properties of the pattern were strongly dependent on the conditions of plasma exposure of the FEP substrate. The physico-chemical properties of the prepared pattern, such as changes in wettability, aging, morphology, and surface chemistry, were determined. Further, we have examined the cellular response of human osteoblasts (U-2 OS) on the modified substrates. The micropattern prepared with a selected combination of surface activation and amount of PMMA for honeycomb construction showed a positive effect on U-2 OS cell adhesion and proliferation. Samples with higher PMMA content (3 and 4 g) formed more periodic hexagonal structures on the surface compared to its lower amount (1 and 2 g), which led to a significant increase in the pattern cytocompatibility compared to pristine or plasma-treated FEP.

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 889
Author(s):  
Klára Fajstavrová ◽  
Silvie Rimpelová ◽  
Dominik Fajstavr ◽  
Václav Švorčík ◽  
Petr Slepička

The development of new biocompatible polymer substrates is still of interest to many research teams. We aimed to combine a plasma treatment of fluorinated ethylene propylene (FEP) substrate with a technique of improved phase separation. Plasma exposure served for substrate activation and modification of surface properties, such as roughness, chemistry, and wettability. The treated FEP substrate was applied for the growth of a honeycomb-like pattern from polystyrene solution. The properties of the pattern strongly depended on the primary plasma exposure of the FEP substrate. The physico-chemical properties such as changes of the surface chemistry, wettability, and morphology of the prepared pattern were determined. The cell response of primary fibroblasts and osteoblasts was studied on a honeycomb pattern. The prepared honeycomb-like pattern from polystyrene showed an increase in cell viability and a positive effect on cell adhesion and proliferation for both primary fibroblasts and osteoblasts.


2015 ◽  
Vol 73 (7) ◽  
pp. 1875-1890 ◽  
Author(s):  
Shamayita Patra ◽  
Sadiya Anjum ◽  
Alok R. Ray ◽  
Bhuvanesh Gupta

Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1205
Author(s):  
Agnieszka Piotrowska-Kirschling ◽  
Joanna Brzeska

Materials science is an interdisciplinary area of studies. This science focuses on the influence of the physico-chemical properties of materials on their application in human everyday lives. The materials’ synthesis should be developed in accordance with sustainable development. Polyurethanes (PUR) represent a significant consumption of plastic in the world. Modification of PUR, e.g., with polysaccharide of natural origin (chitosan, Chit), should have a positive effect on their functional properties and degradability in the natural environment. The basic parameters affecting the scope and direction of changes are the size and quantity of the chitosan particles. The impact assessment of chitosan on the chemical structure, morphology, thermal properties, crystallinity, mechanical properties, flammability, water sorption, adsorption properties, degradability, and biological activity of PUR/Chit composites (without other additives) is discussed in this article. To the best of our knowledge, recent literature does not contain a study discussing the direct impact of the presence of chitosan in the structure of PUR/Chit composite on its properties, regardless of the intended uses. This paper provides an overview of publications, which presents the results of a study on the effect of adding chitosan in polyurethane/chitosan composites without other additives on the properties of polyurethane.


Foods ◽  
2019 ◽  
Vol 8 (7) ◽  
pp. 256 ◽  
Author(s):  
Torrico ◽  
Tam ◽  
Fuentes ◽  
Viejo ◽  
Dunshea

Sugar not only provides the desirable sweetness but its reduction can also alter the physico-chemical properties of foods. The objective of this study was to evaluate the effects of tagatose as a sugar substitute on selected physico-chemical properties and sensory acceptability of strawberry-flavored yogurts. Six yogurt samples with decreasing concentrations of sucrose (8.50 to 1.70 g/100 g) and increasing concentrations of tagatose (0.00 to 9.24 g/100 g) were evaluated. Physico-chemical tests (pH, lactic acid (%), °Brix, water-holding capacity (WHC), viscosity, and color) were conducted to examine the quality and shelf-life of yogurts during 28 days of storage at 4 °C. An acceptability test (n = 55) was conducted to evaluate the sensory characteristics of yogurts. Sucrose reductions by the replacement of up to 80% tagatose showed marginal effects on the selected physico-chemical properties; however, the loss of red color (a*) and increase in yellowness (b*) of the tagatose-substituted samples were significant. Strawberry yogurts with tagatose replacements had similar acceptability scores for all attributes. Sucrose reduction showed a positive effect on the purchase intent of the strawberry yogurts (an increase of 3–30%). These findings can be used to understand the effects of tagatose/sucrose formulations on the acceptability and physico-chemical properties of yogurts.


Author(s):  
A. Sh. Zainullina ◽  
A. Zh. Arystan

The article is devoted to the study of physico-chemical properties of oil fields Uzen, Kenkiyak, Martyshi and study the effect of depressor additives on the rheological properties of oil fields Uzen. The main analyses of oil were carried out, including the content of paraffins, viscosity, pour point. Depressor additives of brands were used during the research MR-1055/980, Deprop 4125, WX 161. It is established that the effect of depressor additives on oil has a positive effect on their physical and chemical characteristics.


Pharmaceutics ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 576 ◽  
Author(s):  
Andrea Della Bella ◽  
Michele Müller ◽  
Andrea Danani ◽  
Luciano Soldati ◽  
Ruggero Bettini

Physico-chemical properties of lactose are key factors in adhesive mixtures used as dry powder inhaler (DPI). Despite the abundant literature on this topic, the effect of the polymorphism and pseudo-polymorphism of lactose has been seldom investigated and discussed although often lactose used in DPI is subjected to unit operations, which may alter its solid-state properties. Here, we studied the aerosolization performance of salbutamol sulphate (SS) or budesonide (BUD) formulations by investigating the effect of lactose pseudopolymorphism in ternary (coarse lactose/fine lactose/drug) and binary (coarse lactose/drug) mixtures. An improvement of the aerosolization performance of SS formulations with the increase of the amount of fine micronized lactose up to 30% (fine particle fraction (FPF) = 57%) was observed. Micronized lactose contained hygroscopic anhydrous α-lactose, which converted to α-lactose monohydrate at ambient conditions. This implied that the positive effect of fines on the aerosolization performance decreased and eventually disappeared with the formulation aging. Positive effect on SS deposition was observed also with binary mixtures with anhydrous lactose, whereas the opposite occurred with budesonide-containing formulations. The collected data demonstrated the crucial role of the carrier crystal form on the positive effect of fines on the deposition.


2014 ◽  
Vol 13 (2) ◽  
pp. 489-499 ◽  
Author(s):  
Y. C. Ho ◽  
I. Norli ◽  
Abbas F. M. Alkarkhi ◽  
N. Morad

In view of green developments in water treatment, plant-based flocculants have become the focus due to their safety, degradation and renewable properties. In addition, cost and energy-saving processes are preferable. In this study, malva nut gum (MNG), a new plant-based flocculant, and its composite with Fe in water treatment using single mode mixing are demonstrated. The result presents a simplified extraction of the MNG process. MNG has a high molecular weight of 2.3 × 105 kDa and a high negative charge of −58.7 mV. From the results, it is a strong anionic flocculant. Moreover, it is observed to have a branch-like surface structure. Therefore, it conforms to the surface of particles well and exhibits good performance in water treatment. In water treatment, the Fe-MNG composite treats water at pH 3.01 and requires a low concentration of Fe and MNG of 0.08 and 0.06 mg/L, respectively, when added to the system. It is concluded that for a single-stage flocculation process, physico-chemical properties such as molecular weight, charge of polymer, surface morphology, pH, concentration of cation and concentration of biopolymeric flocculant affect the flocculating performance.


2016 ◽  
Vol 857 ◽  
pp. 416-420 ◽  
Author(s):  
Antoni ◽  
Stephen Wibiatma Wijaya ◽  
Juan Satria ◽  
Agung Sugiarto ◽  
Djwantoro Hardjito

Geopolymer that was made with high CaO content fly ash was found to have higher compressive strength than the low CaO fly ash, using the same mixture composition. This effect could be due to the physico-chemical properties of the fly ash, in respect to its particle size or the chemical composition. Although it was not widely published, the occurrence of flash setting of geopolymer was known to occur when using high CaO content fly ash as the precursor. Geopolymer paste may solidify within minutes after the addition of alkali activators, making it very difficult to cast in big volume. This paper investigate the effect of borax addition to the high calcium fly ash-based geopolymer mixture to reduce the occurrence of flash setting. It was found that the setting time can be extended significantly, with the addition of 5% borax, by mass, of fly ash. The addition of borax also have positive effect on increasing the compressive strength of geopolymer.


2016 ◽  
Vol 60 ◽  
pp. 30-37 ◽  
Author(s):  
Sakila Jesmin ◽  
Abdullah Al-Jubayer ◽  
Saad bin Eusuf ◽  
A.H.M. Kamal ◽  
Jahid M.M. Islam ◽  
...  

The research was designed to extend shelf life of stored strawberry by bioactive chitosan coating. Strawberry fruits were dipped for 2 min in different concentration of irradiated chitosan (300, 500, 1000 and 1500 ppm) solution which were subjected to different gamma radiation doses (30, 40, 50 and 60 kGy) while uncoated fruits were served as control. Samples were packed in zip bags and stored in 4°C and kept for observation. Fruits treated with 50 kGy irradiated chitosan at 1500 ppm concentration showed significant delays in the change of weight loss, decay percentage, pH, and ascorbic acid content as compared with the uncoated control fruits. Samples stored in 4°C and packed in zip bags showed an increased shelf life up to 21 days whereas control samples with same condition could maintain edible quality only up to 3 days. Compared to the controls, all coating formulations had positive effect on the inhibition of cell wall degrading enzymes. These findings suggest that the use of irradiated chitosan coatings can be very useful for extending the shelf-life and maintaining quality of strawberry fruit.


Author(s):  
Ahmed M A Hamad

Dietary fiber considered a main ingredient of food products. The Increased attention of DF in food products is caused by an increased interest in developing health foods, Dietary fiber is consisting polysaccharides and oligosaccharides, and cellulose hemicelluloses, resistant starch, pectin substances, and gums, also the of DF has wide application in food processing because its technological properties. for exampleDF could extend the shelf-life of the product by the water-holding capacity the DF important in the human diet. the food rich in fibre such as cereals, nuts, fruits and vegetables have a positive effect on health since their consumption help in prevent many diseases. Dietary fibre can be used in many functional foods like drinks, beverages, bakery, and meat products. effect of different processing treatments (like cooking, canning, grinding, boiling, frying) change the physico-chemical properties of dietary fibre and improves their functionality. Dietary fibre can be analytical by different methods, mainly by: enzymic gravimetric and enzymic- chemical methods. This paper presents the classification, applications, and functions of dietary fibre in different food products.


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