scholarly journals Economic Analysis of a New Business for Liposome Manufacturing Using a High-Pressure System

Processes ◽  
2020 ◽  
Vol 8 (12) ◽  
pp. 1604
Author(s):  
Paolo Trucillo ◽  
Roberta Campardelli ◽  
Silvia Iuorio ◽  
Paolo De Stefanis ◽  
Ernesto Reverchon
Keyword(s):  
Economic Analysis ◽  
Flow Analysis ◽  
Industrial Applications ◽  
Selling Price ◽  
Personnel Cost ◽  
Pressure System ◽  
Goods And Services ◽  
Payback Time ◽  
New Business ◽  
Return On Sales

Supercritical assisted Liposome formation (SuperLip) is a lab-scale process for the production of liposomes. SuperLip was recognized as being a versatile supercritical assisted technique for the encapsulation of molecules for different industrial applications, such as pharmaceutic, cosmetic, textile, and nutraceutic purposes. The aim of this work was to perform an economic analysis to assess the profitability of the SuperLip process. The liposomes market was analyzed and the SuperLip process was compared to other techniques in terms of manufacturing advantages using the Canvas and Strengths, Weaknesses, Opportunities, and Treats (S.W.O.T.) models. SuperLip Plant Capital Expenditures (CAPEX) were estimated, and plant Operating Expenditures (OPEX) were also evaluated and integrated with personnel cost and other plant goods and services. A profit and loss statement was generated, together with a cash flow analysis. According to the market average selling price, liposome price is 1.8 €/mL; in order to join the market rapidly, the selling price of liposomes produced using SuperLip was set at 1.1 €/mL. A payback time has been identified at the fourth year of business. Economic indexes such as ROI and ROS were calculated on a 10-year business prospect, obtaining about a 230% return on investment and a 26.7% return on sales.

scholarly journals Economic Assessment of Bioethanol Recovery Using Membrane Distillation for Food Waste Fermentation

2020 ◽  
Vol 7 (1) ◽  
pp. 15 ◽  
Author(s):  
Noor Intan Shafinas Muhammad ◽  
Kurt A. Rosentrater
Keyword(s):  
Food Waste ◽  
Fermentation Broth ◽  
Energy Requirement ◽  
Flow Analysis ◽  
Economic Assessment ◽  
Membrane Distillation ◽  
Industrial Applications ◽  
Yeast Fermentation ◽  
Selling Price ◽  
Commercial Scale

Ethanol is a material that has a high demand from different industries such as fuel, beverages, and other industrial applications. Commonly, ethanol has been produced from yeast fermentation using sugar crops as a feedstock. However, food waste (FW) was found to be one of the promising resources to produce ethanol because it contained a higher amount of glucose. Generally, column distillation has been used to separate ethanol from the fermentation broth, but this operation is considered an energy-intensive process. On the contrary, membrane distillation is expected to be more practical and cost-effective because of its lower energy requirement. Therefore, this study aims to make a comparison of economic performance on FW fermentation with membrane distillation and a conventional distillation system using techno-economy analysis (TEA) method. A commercial-scale FW fermentation plant was modeled using SuperPro Designer V9.0 Modeling. Discounted cash flow analysis was employed to determine ethanol minimum selling price (MSP) for both distillation systems at 10% of the internal rate of return. Results from this analysis showed that membrane distillation has a higher MSP than a conventional process, $6.24 and $2.41 per gallon ($1.65 and $0.64 per liter) respectively. Hence, this study found that membrane distillation is not economical to be implemented in commercial-scale ethanol production.

scholarly journals Techno-Economic Analysis of a Hyaluronic Acid Production Process Utilizing Streptococcal Fermentation

Processes ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 241
Author(s):  
Rafael G. Ferreira ◽  
Adriano R. Azzoni ◽  
Maria Helena Andrade Santana ◽  
Demetri Petrides
Keyword(s):  
Hyaluronic Acid ◽  
Economic Analysis ◽  
Lower Cost ◽  
Value Added ◽  
Production Costs ◽  
Selling Price ◽  
Baseline Scenario ◽  
Adhesive Properties ◽  
Fed Batch Culture ◽  
Economic Analyses

Hyaluronic acid (HA) is a polysaccharide of alternating d-glucuronic acid and N-acetyl-d-glucosamine residues present in the extracellular matrix of connective, epithelial, and nervous tissues. Due to its singular hydrating, rheological and adhesive properties, HA has found numerous cosmetic and medical applications. However, techno-economic analyses of high value-added bioproducts such as HA are scarce in the literature. Here, we present a techno-economic analysis of a process for producing HA using Streptococcus zooepidemicus, simulated in SuperPro Designer. In the baseline scenario, HA is produced by batch fermentation, reaching 2.5 g/L after 24 h. It is then centrifuged, diafiltered, treated with activated carbon and precipitated with isopropanol. The product is suitable for topical formulations and its production cost was estimated as 1115 $/kg. A similar scenario, based on fed-batch culture and assuming a titer of 5.0 g/L, led to a lower cost of 946 $/kg. Moreover, in two additional scenarios, 10% of the precipitated HA is diverted to the production of a highly pure and high-molecular weight HA, suitable for injectable applications. These scenarios resulted in higher capital and operating costs, but also in higher profits, because HA for injectable use has a higher selling price that more than compensates for its higher production costs.

Servitization of Industry: New Evidence

2021 ◽  
Vol 65 (8) ◽  
pp. 22-30
Author(s):  
V. Kondrat’ev ◽  
G. Kedrova ◽  
V. Popov
Keyword(s):  
Economic Policy ◽  
Business Models ◽  
Manufacturing Firms ◽  
Policy Implications ◽  
New Economic Policy ◽  
Firm Level ◽  
Policy Regime ◽  
Goods And Services ◽  
New Business ◽  
Use Of Services

A significant increase in the use of services is observed for some industries in GVCs (Global Value Chains). The paper has shed light on important dimension of the servitization which is the sale and export of services by manufacturing firms, often bundled together with goods. Firm-level data confirm that many firms are involved both in the production of goods and services and that there are complementarities between these activities. Not only manufacturing firms are involved in the distribution, transport and logistics services needed for their international operations in GVCs but also, they provide installation, maintenance, repair services as well as a variety of other business support and complementary services that increase value for their customers. The servitization has important policy implications, particularly when taking into account the fact that trade in services is generally more restricted than trade in goods. As the lines between goods and services are blurred, economic policy today might be more challenging than in the past, particularly for companies moving to new business models that imply more interactions with customers and a more intensive use of digital technologies. Services themselves are split into different modes of supply for which there are different levels of economic policy. A closer look at the mechanisms of value creation in the case of services suggests that there are still the needs of new economic policy addressed at business models described as value networks or value shops. As technologies become more disruptive and more companies move to ‘servicified’ GVCs, the need for a more consistent international economic policy regime, particularly at the multilateral level, will become more urgent.

scholarly journals Techno-Economic Analysis of Biomass Energy Utilization through Gasification Technology for Sustainable Energy Production and Economic Development in Nigeria

2018 ◽  
Vol 2018 ◽  
pp. 1-16 ◽  
Author(s):  
Gbeminiyi M. Sobamowo ◽  
Sunday J. Ojolo
Keyword(s):  
Economic Analysis ◽  
Rural Areas ◽  
Financial Incentives ◽  
Capital Investment ◽  
Biomass Gasification ◽  
Biomass Energy ◽  
Energy Utilization ◽  
Maintenance Cost ◽  
Selling Price ◽  
Gasification Technology

Nigeria has not been able to provide enough electric power to her about 200 million people. The last effort by the federal government to generate 6000 MW power by the end of 2009 failed. Even with the available less than 6000 MW of electricity generated in the country, only about 40% of the population have access to the electricity from the National Grid, out of which, urban centers have more than 80% accessibility while rural areas, which constitute about 70% of the total population, have less than 20% of accessibility to electricity. This paper addresses the possibility of meeting the energy demand in Nigeria through biomass gasification technology. The techno-economic analysis of biomass energy is demonstrated and the advantages of the biomass gasification technology are presented. Following the technical analysis, Nigeria is projected to have total potential of biomass of about 5.5 EJ in 2020 which has been forecast to increase to about 29.8 EJ by 2050. Based on a planned selling price of $0.727/kWh, the net present value of the project was found to be positive, the cost benefit ratio is greater than 1, and the payback period of the project is 10.14 years. These economic indicators established the economic viability of the project at the given cost. However, economic analysis shows a selling price of $0.727/kWh. Therefore, the capital investment cost, operation and maintenance cost, and fuel cost can be reduced through the development of the gasification system using local materials, purposeful and efficient plantation of biomass for the energy generation, giving out of financial incentives by the government to the investors, and locating the power plant very close to the source of feedstock generation.

MACHINE VISION 1992–1996, TECHNOLOGY PROGRAM IN FINLAND

1996 ◽  
Vol 10 (01) ◽  
pp. 3-13 ◽  
Author(s):  
ANTTI J. SOINI
Keyword(s):  
Machine Vision ◽  
Manufacturing Industry ◽  
Technology Development ◽  
New Technology ◽  
Robot Vision ◽  
Industrial Applications ◽  
Technology Program ◽  
Research Organizations ◽  
Innovative Products ◽  
New Business

Machine vision technology has attracted a strong interest among Finnish research organizations, which has resulted in many innovative products for industry. Despite this goal users were very skeptical towards machine vision and its robustness in harsh industrial environments. Therefore the Technology Development Centre, TEKES, which funds technology related research and development projects in universities and individual companies in Finland, decided to start a national technology program, "Machine Vision 1992–1996". Led by industry, the program boosts research in machine vision technology and seeks to put the research results to work in practical industrial applications. The emphasis is on nationally important, demanding applications. The program will create new business for machine vision producers and encourage the process and manufacturing industry to take advantage of this new technology. So far 60 companies and all major universities and research centers in Finland are working on our forty different projects. The key themes are Process Control, Robot Vision and Quality Control.

Experimental Investigation of the Diffuser Vane Clearance Effect in a Centrifugal Compressor Stage With Adjustable Diffuser Geometry: Part II—Detailed Flow Analysis

2014 ◽  
Vol 137 (3) ◽  
Author(s):  
Stefan Ubben ◽  
Reinhard Niehuis
Keyword(s):  
Centrifugal Compressor ◽  
Pressure Ratio ◽  
Flow Analysis ◽  
Industrial Applications ◽  
Experimental Investigations ◽  
Stall Margin ◽  
Diffuser Flow ◽  
Radial Gap ◽  
The Impact ◽  
Vane Angle

Adjustable diffuser vanes offer an attractive design option for centrifugal compressors applied in industrial applications. However, the knowledge about the impact on compressor performance of a diffuser vane clearance between vane and diffuser wall is still not satisfying. This two-part paper summarizes results of experimental investigations performed with an industrial-like centrifugal compressor. Particular attention was directed toward the influence of the diffuser clearance on the operating behavior of the entire stage, the pressure recovery in the diffuser, and on the diffuser flow by a systematic variation of the parameters diffuser clearance height, diffuser vane angle, radial gap between impeller exit and diffuser inlet, and rotor speed. In Part I it was shown that an one-sided diffuser clearance is able to contribute to an increase in flow range, stall margin, pressure ratio, and efficiency. In order to reveal the relevant flow phenomena, in Part II the results of detailed measurements of the pressure distribution at diffuser exit and particle image velocimetry (PIV) measurements inside the diffuser channel performed at three clearance configurations and three diffuser angles at a fixed radial gap are discussed. It was found that, for defined diffuser configurations, the clearance flow amplifies the diffuser throat vortex capable to reduce the loading of the highly loaded vane pressure side and to support a more homogenous diffuser flow. It turned out that the co-action of the geometry parameter diffuser vane angle and diffuser clearance height is of particular importance. The experimental results are published as an open computational fluid dynamics (CFD) testcase “Radiver 2.”

Using Government Performance Management Data to Identify New Business Opportunities: Examples from Government Services Outsourcing in the United States

2004 ◽  
Vol 70 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Lawrence L. Martin ◽  
Karun K. Singh
Keyword(s):  
Private Sector ◽  
Performance Management ◽  
The United States ◽  
Government Performance ◽  
Goods And Services ◽  
Performance Budgeting ◽  
The World ◽  
Business Opportunities ◽  
New Business ◽  
And Performance

This article describes how the private sector can utilize government performance management data to identify business opportunities. Governments around the world today are making increased use of outsourcing, performance management and performance budgeting. Utilizing readily available data that can often be accessed via the World Wide Web, private sector businesses can identify current business opportunities in terms of what services governments are outsourcing, in what amounts and at what costs. Additionally, potential future business opportunities can be identified in terms of what services governments are currently providing in-house, at what costs and with what results. Armed with this information, private sector businesses can readily identify markets for their goods and services.

scholarly journals The impact of telematics on traffic safety

2021 ◽  
Author(s):  
Igor Jelić ◽  
◽  
Maja Balenović ◽  
Keyword(s):  
Environmental Pollution ◽  
Fuel Consumption ◽  
Traffic Safety ◽  
Traffic Congestion ◽  
Waiting Times ◽  
High Mobility ◽  
Goods And Services ◽  
New Business ◽  
Business Approach ◽  
The Impact

The development of traffic that is conditioned by the high mobility of people, goods and services must be in line with the principles of sustainable development, but it is only possible if the consumption of renewable resources is less than natural renewal opportunities. The future is in implementation of innovative technologies such as telematics systems that offer not only technical solutions but also a new way of life, a new business approach and a new cultural aspect of living for all traffic participants. Advanced telematics solutions such as inflow management and speed limit management greatly help to solve traffic problems, like incidents, environmental pollution, traffic congestion, fuel consumption, etc. Impact of telematics can increase safety but can also introduce new risks for drivers that pose special challenges to traffic psychology and public health. In order to reduce traffic congestion, longer waiting times, environmental pollution, reduce fuel consumption in incident situation various advanced grammatical solutions have been implemented in order to reduce these problems. Telematics, using techniques such as informatics, optoelectronics, automatics and telecommunications, helps to reduce costs of transportation potential management, improves the security and reliability of the transportation service.

scholarly journals Economic analysis of up-to-date sour cherry or in Hungary

2008 ◽  
Vol 14 (1-2.) ◽  
Author(s):  
F. Apáti
Keyword(s):  
Economic Analysis ◽  
Sour Cherry ◽  
High Standard ◽  
Production Costs ◽  
Major Portion ◽  
Selling Price ◽  
Average Yield ◽  
Direct Production ◽  
Personal Cost ◽  
Profit Analysis

In this study cost-profit analysis is carried out to up-to-date Hungarian sour cherry orchards. These orchards cover only 1 to 3 thousand hectares from the sour cherry territory of 16 thousand hectares. In a many-year-average a yield of 15 tons per hectare may be reached in up-to-date sour cherry orchards cultivated under high standard conditions. Per hectare direct production costs take up of approximately 1000 thousand HUF, from which the major portion (60%) is accounted for the personal cost of harvesting. Regarding the above mentioned average yield and a selling price of 100 HUF per kilogram a revenue of 1 500 thousand HUF may be realized, which results in a per hectare contribution of 500 thousand HUF. To sum up, regarding the present extremely unfavourable selling price only reaching an average yield of 15 to 20 tons per hectare may lead to appropriate profit.

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