scholarly journals Diversity and Distribution of Viruses Infecting Wild and Domesticated Phaseolus spp. in the Mesoamerican Center of Domestication

Viruses ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1153
Author(s):  
Elizabeth Chiquito-Almanza ◽  
Juan Caballero-Pérez ◽  
Jorge A. Acosta-Gallegos ◽  
Victor Montero-Tavera ◽  
Luis Antonio Mariscal-Amaro ◽  
...  
Keyword(s):  
Virus Disease ◽  
Viral Disease ◽  
Bean Common Mosaic Virus ◽  
Small Rna Sequencing ◽  
Virus Species ◽  
Emerging Viruses ◽  
Complete Sequences ◽  
The Impact ◽  
Important Disease ◽  
Wild Beans

Viruses are an important disease source for beans. In order to evaluate the impact of virus disease on Phaseolus biodiversity, we determined the identity and distribution of viruses infecting wild and domesticated Phaseolus spp. in the Mesoamerican Center of Domestication (MCD) and the western state of Nayarit, Mexico. We used small RNA sequencing and assembly to identify complete or near-complete sequences of forty-seven genomes belonging to nine viral species of five genera, as well as partial sequences of two putative new endornaviruses and five badnavirus- and pararetrovirus-like sequences. The prevalence of viruses in domesticated beans was significantly higher than in wild beans (97% vs. 19%; p < 0.001), and all samples from domesticated beans were positive for at least one virus species. In contrast, no viruses were detected in 80–83% of the samples from wild beans. The Bean common mosaic virus and Bean common mosaic necrosis virus were the most prevalent viruses in wild and domesticated beans. Nevertheless, Cowpea mild mottle virus, transmitted by the whitefly Bemisia tabaci, has the potential to emerge as an important pathogen because it is both seed-borne and a non-persistently transmitted virus. Our results provide insights into the distribution of viruses in cultivated and wild Phaseolus spp. and will be useful for the identification of emerging viruses and the development of strategies for bean viral disease management in a center of diversity.

scholarly journals Threshold Dynamics in a Model for Zika Virus Disease with Seasonality

2021 ◽  
Vol 83 (4) ◽  
Author(s):  
Mahmoud A. Ibrahim ◽  
Attila Dénes
Keyword(s):  
Zika Virus ◽  
Reproduction Number ◽  
Virus Disease ◽  
Threshold Dynamics ◽  
Global Dynamics ◽  
Threshold Parameter ◽  
Globally Asymptotically Stable ◽  
Linear Integral ◽  
The Impact ◽  
Disease Free

AbstractWe present a compartmental population model for the spread of Zika virus disease including sexual and vectorial transmission as well as asymptomatic carriers. We apply a non-autonomous model with time-dependent mosquito birth, death and biting rates to integrate the impact of the periodicity of weather on the spread of Zika. We define the basic reproduction number $${\mathscr {R}}_{0}$$ R 0 as the spectral radius of a linear integral operator and show that the global dynamics is determined by this threshold parameter: If $${\mathscr {R}}_0 < 1,$$ R 0 < 1 , then the disease-free periodic solution is globally asymptotically stable, while if $${\mathscr {R}}_0 > 1,$$ R 0 > 1 , then the disease persists. We show numerical examples to study what kind of parameter changes might lead to a periodic recurrence of Zika.

scholarly journals The impact of environmental variables on the spread of COVID-19 in the Republic of Korea

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yong Kwan Lim ◽  
Oh Joo Kweon ◽  
Hye Ryoun Kim ◽  
Tae-Hyoung Kim ◽  
Mi-Kyung Lee
Keyword(s):  
Environmental Factors ◽  
Virus Disease ◽  
Environmental Parameters ◽  
Environmental Data ◽  
Republic Of Korea ◽  
Metropolitan Region ◽  
Health Concern ◽  
Ozone Level ◽  
The Republic ◽  
The Impact

AbstractCorona virus disease 2019 (COVID-19) has been declared a global pandemic and is a major public health concern worldwide. In this study, we aimed to determine the role of environmental factors, such as climate and air pollutants, in the transmission of COVID-19 in the Republic of Korea. We collected epidemiological and environmental data from two regions of the Republic of Korea, namely Seoul metropolitan region (SMR) and Daegu-Gyeongbuk region (DGR) from February 2020 to July 2020. The data was then analyzed to identify correlations between each environmental factor with confirmed daily COVID-19 cases. Among the various environmental parameters, the duration of sunshine and ozone level were found to positively correlate with COVID-19 cases in both regions. However, the association of temperature variables with COVID-19 transmission revealed contradictory results when comparing the data from SMR and DGR. Moreover, statistical bias may have arisen due to an extensive epidemiological investigation and altered socio-behaviors that occurred in response to a COVID-19 outbreak. Nevertheless, our results suggest that various environmental factors may play a role in COVID-19 transmission.

scholarly journals The Impact of Tick-Borne Diseases on the Bone

2021 ◽  
Vol 9 (3) ◽  
pp. 663
Author(s):  
Imran Farooq ◽  
Tara J. Moriarty
Keyword(s):  
Bone Marrow ◽  
Lyme Disease ◽  
Bone Loss ◽  
Human Body ◽  
Virus Disease ◽  
Hemorrhagic Fever ◽  
Research Literature ◽  
Tick Borne Encephalitis ◽  
Bone Marrow Function ◽  
The Impact

Tick-borne infectious diseases can affect many tissues and organs including bone, one of the most multifunctional structures in the human body. There is a scarcity of data regarding the impact of tick-borne pathogens on bone. The aim of this review was to survey existing research literature on this topic. The search was performed using PubMed and Google Scholar search engines. From our search, we were able to find evidence of eight tick-borne diseases (Anaplasmosis, Ehrlichiosis, Babesiosis, Lyme disease, Bourbon virus disease, Colorado tick fever disease, Tick-borne encephalitis, and Crimean–Congo hemorrhagic fever) affecting the bone. Pathological bone effects most commonly associated with tick-borne infections were disruption of bone marrow function and bone loss. Most research to date on the effects of tick-borne pathogen infections on bone has been quite preliminary. Further investigation of this topic is warranted.

scholarly journals The impact of active surveillance and health education on an Ebola virus disease cluster — Kono District, Sierra Leone, 2014–2015

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Tasha Stehling-Ariza ◽  
Alexander Rosewell ◽  
Sahr A. Moiba ◽  
Brima Berthalomew Yorpie ◽  
Kai David Ndomaina ◽  
...  
Keyword(s):  
Health Education ◽  
Sierra Leone ◽  
Active Surveillance ◽  
Ebola Virus ◽  
Virus Disease ◽  
Ebola Virus Disease ◽  
Disease Cluster ◽  
The Impact ◽  
Kono District

scholarly journals Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Sushila A. Toulmin ◽  
Chaitali Bhadiadra ◽  
Andrew J. Paris ◽  
Jeffrey H. Lin ◽  
Jeremy Katzen ◽  
...  
Keyword(s):  
Antigen Presentation ◽  
Sendai Virus ◽  
Virus Disease ◽  
Viral Disease ◽  
Type Ii ◽  
Virus Infections ◽  
Alveolar Cells ◽  
Inflammatory Stimuli ◽  
Respiratory Homeostasis ◽  
Mhcii Expression

AbstractType II alveolar cells (AT2s) are critical for basic respiratory homeostasis and tissue repair after lung injury. Prior studies indicate that AT2s also express major histocompatibility complex class II (MHCII) molecules, but how MHCII expression by AT2s is regulated and how it contributes to host defense remain unclear. Here we show that AT2s express high levels of MHCII independent of conventional inflammatory stimuli, and that selective loss of MHCII from AT2s in mice results in modest worsening of respiratory virus disease following influenza and Sendai virus infections. We also find that AT2s exhibit MHCII presentation capacity that is substantially limited compared to professional antigen presenting cells. The combination of constitutive MHCII expression and restrained antigen presentation may position AT2s to contribute to lung adaptive immune responses in a measured fashion, without over-amplifying damaging inflammation.

Hospitalitas Kristen Yang Hampir Hilang Pada Kasus Kematian Salah Satu Anggota Masyarakat Di Dusun Beringin, Luwu Utara, Sulawesi Selatan Akibat Covid-19

2021 ◽  
Author(s):  
desna rura sarapang
Keyword(s):  
Virus Disease ◽  
Social Distancing ◽  
Indonesian Government ◽  
Risk Of Death ◽  
The Earth ◽  
Corona Virus ◽  
The World ◽  
Global World ◽  
The Impact ◽  
Christian Hospitality

The emergence of a new virus in the global world at the end of 2019, namely Corona Virus Disease 2019, brought tremendous excitement to all inhabitants of the earth. The emergence of this virus brings tremendous concern and fear to the world because the spread of this virus is quite fast, even the most frightening is that the risk of death of people exposed to this virus is very large. Indonesia itself, cannot avoid the impact of this Covid-19 case. As a form of efforts to prevent and minimize transmission of the virus, the Indonesian government has issued a social distancing / physical distancing recommendation. This situation also causes the interaction between communities to be very limited. This situation seems to be able to eliminate hospitality among the community. This paper aims to emphasize the importance of maintaining the value of Christian hospitality in society amid the Covid-19 pandemic.

Maternal Correlates of Poliomyelitis Vaccination Uptake: Evidence from Afghanistan, Pakistan, and Nigeria

2021 ◽  
Author(s):  
Muhammad Muzammil ◽  
Sameen Zafar ◽  
Shazia Aziz ◽  
Muhammad Usman Bhutta ◽  
Rafi Amir-Ud-Din
Keyword(s):  
Multinomial Logistic Regression ◽  
Viral Disease ◽  
Household Wealth ◽  
Demographic And Health Surveys ◽  
Wealth Status ◽  
Vaccination Uptake ◽  
Agriculture Sector ◽  
Polio Vaccination ◽  
Working Status ◽  
The Impact

Poliomyelitis (polio) is a communicable viral disease that mainly affects under-5 children. This study focuses on the impact of women’s empowerment and women’s working status on the uptake of polio vaccination of children in polio-endemic countries, including Pakistan and Afghanistan, and Nigeria, the latter of which has recently been declared polio-free. The polio vaccination status can be divided into no vaccination (NV), incomplete vaccination (IV), and complete vaccination. We used data from the most recent Demographic and Health Surveys (DHS) rounds for this manuscript. Multinomial logistic regression-based estimates suggest that mothers’ working status, empowerment, age, education, father’s education, and household wealth status reduce the risk of NV and IV in the polio-endemic countries (Afghanistan and Pakistan) and Nigeria. In addition, the mothers’ working status, empowerment, age, education, and father’s education increase the child’s healthcare information that helps complete polio vaccination of the child. On the other hand, the children whose mothers work in the agriculture sector or are engaged in a blue-collar job are more likely to remain unvaccinated than women in white-collar jobs. Similarly, mothers engaged in government jobs are more likely to get their children fully vaccinated than unemployed mothers. Thus, as a child’s polio vaccination is strongly dependent on a mother’s working status and empowerment, the focus of public policy on empowering women and promoting their labor force participation may increase polio vaccination uptake, besides adopting other measures to increase immunization.

UPDATE ON CARDIOVASCULAR IMPLICATIONS OF COVID 19

2021 ◽  
pp. 238-242
Author(s):  
Pradeep Kumar Radhakrishnan ◽  
Gayathri Ananyajyothi Ambat ◽  
Roshini Ambat ◽  
Syed Ilas Basha ◽  
Hema Prakash ◽  
...  
Keyword(s):  
Virus Disease ◽  
Systemic Vasculitis ◽  
Myocardial Damage ◽  
Viral Disease ◽  
Cardiac Damage ◽  
Corona Virus ◽  
Global Pandemic ◽  
Acute Myocardial Injury ◽  
Exercise Induced

On March 11 2020 WHO declares corona viral disease as a global pandemic .COVID 19 pandemic has taken the world by storm and many countries like India is now experiencing a second surge due to mutant strains. Global health emergency has been precipitated by this corona virus disease caused by SARS CoV2.Acute and intermediate effects on cardiovascular system are becoming obvious with progression of time. SARS-CoV-2-related endothelial dysfunction results in an augmented risk for venous thromboembolism, systemic vasculitis, endothelial cell apoptosis, and inammation in various organs. Acute infections have troponin elevation more due to indirect cardiac damage though denite patterns of direct damage do exist. Intermediate evaluation in patients with resolved infections shows increased incidence of exercise induced arrhythmias and residual cardiovascular symptoms. The virus with its zoonotic origin based upon its genomic identity to bat derived SARS corona virus has a human to human transmission mode.ACE 2 receptors facilitate cellular entry and has been implicated in direct and indirect myocardial damage. Myocarditis, acute myocardial injury, arrhythmias and thromboembolism dominates the clinical picture. Role of imaging must be dened in relation to relevant clinical ndings. With arrival of vaccine and widespread vaccination global programs, we can look forward to understanding and managing long term complications of this disease. Prognostic implications of a resolved disease need to be evaluated by future studies.

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