Historical prerequisites to personalized medicine: constitutional approach to the diagnosis, prevention and treatment of traditional medical systems in the world

2020 ◽  
pp. 21-34
Author(s):  
S. Chudakov ◽  
D. Shmakova ◽  
F. Shmakov ◽  
S. Kachevskaya ◽  
G. Kopeliovich ◽  
...  

The purpose of this review was to study historical prerequisites for the development of personalized medicine and the need to create an accessible personalization method based on the constitutional approach using ideas and methodology of the corresponding historical stage revealed during all periods of development of medicine. The process of forming a constitutional approach in medicine is described in the article, as well as the psychophysiological patterns that form personalized medicine in various medical schools of the East and West, and also modern academic medicine, and some vivid examples of correlations between the constitutional types of different schools and pathological processes are presented.

2020 ◽  
Vol 20 (6) ◽  
pp. 410-416 ◽  
Author(s):  
Ning-Ning Liu ◽  
Jing-Cong Tan ◽  
Jingquan Li ◽  
Shenghui Li ◽  
Yong Cai ◽  
...  

The outbreak of COVID-19 due to SARS-CoV-2 originally emerged in Wuhan in December 2019. As of March 22, 2020, the disease spread to 186 countries, with at least 305,275 confirmed cases. Although there has been a decline in the spread of the disease in China, the prevalence of COVID-19 around the world remains serious despite containment efforts undertaken by national authorities and the international community. In this article, we systematically review the brief history of COVID-19 and its epidemic and clinical characteristics, highlighting the strategies used to control and prevent the disease in China, which may help other countries respond to the outbreak. This pandemic emphasizes the need to be constantly alert to shifts in both the global dynamics and the contexts of individual countries, making sure that all are aware of which approaches are successful for the prevention, containment and treatment of new diseases, and being flexible enough to adapt the responses accordingly.


Vaccines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 597
Author(s):  
Daniela Luvero ◽  
Salvatore Lopez ◽  
Giorgio Bogani ◽  
Francesco Raspagliesi ◽  
Roberto Angioli

Cervical cancer (CC) is the second leading cause of cancer death in women aged 20–39 years. Persistent infection with oncogenic types of human papillomavirus (HPV) represents the most important risk factor for the development of cervical cancer. Three HPVs vaccines are currently on the global market: bivalent, quadrivalent, and nonavalent. The nonavalent vaccine provides protection against almost 90% of HPV-related CC. Despite availability of primary and secondary prevention measures, CC persists as one of the most common cancers among women around the world. Although CC is a largely preventable disease, management of persistent or recurrent CC no longer amenable to control with surgery or radiation therapy has not improved significantly with the progress of modern chemotherapy and disseminated carcinoma of the cervix remains a discouraging clinical entity with a 1-year survival rate between 10% and 15%. Over the last few years, there has been increasing interest in immunotherapy as a strategy to fight tumors. This article focuses on recent discoveries about the HPV vaccine and immunotherapies in the prevention and treatment of CC, highlighting the future view.


2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Deborah Bedoll ◽  
Marta van Zanten ◽  
Danette McKinley

Abstract Background Accreditation systems in medical education aim to assure various stakeholders that graduates are ready to further their training or begin practice. The purpose of this paper is to explore the current state of medical education accreditation around the world and describe the incidence and variability of these accreditation agencies worldwide. This paper explores trends in agency age, organization, and scope according to both World Bank region and income group. Methods To find information on accreditation agencies, we searched multiple online accreditation and quality assurance databases as well as the University of Michigan Online Library and the Google search engine. All included agencies were recorded on a spreadsheet along with date of formation or first accreditation activity, name changes, scope, level of government independence, accessibility and type of accreditation standards, and status of WFME recognition. Comparisons by country region and income classification were made based on the World Bank’s lists for fiscal year 2021. Results As of August 2020, there were 3,323 operating medical schools located in 186 countries or territories listed in the World Directory of Medical Schools. Ninety-two (49%) of these countries currently have access to undergraduate accreditation that uses medical-specific standards. Sixty-four percent (n = 38) of high-income countries have medical-specific accreditation available to their medical schools, compared to only 20% (n = 6) of low-income countries. The majority of World Bank regions experienced the greatest increase in medical education accreditation agency establishment since the year 2000. Conclusions Most smaller countries in Europe, South America, and the Pacific only have access to general undergraduate accreditation, and many countries in Africa have no accreditation available. In countries where medical education accreditation exists, the scope and organization of the agencies varies considerably. Regional cooperation and international agencies seem to be a growing trend. The data described in our study can serve as an important resource for further investigations on the effectiveness of accreditation activities worldwide. Our research also highlights regions and countries that may need focused accreditation development support.


Author(s):  
Katarzyna Pieklarz ◽  
◽  
Zofia Modrzejewska

Epidemics of infectious diseases have always been a threat to humanity and have contributed to increased mortality in the affected areas. This also applies to a new species of coronavirus identified in 2019, SARS-CoV-2, which is responsible for the COVID-19 pandemic. Despite preventive measures implemented all over the world to minimise the spread of the pathogen as well as the development of vaccines, which have been approved for emergency use, the situation is still worrying. Moreover, the problem is exacerbated by the lack of targeted treatments for COVID-19 patients. One possible solution is the using preparations based on natural raw materials, including chitosan. This biopolymer is of great interest due to a number of unique biological properties, among which its antiviral effect is a key feature. Hence, this paper presents the application possibilities of chitosan-based solutions in the prevention and treatment of viral diseases, with particular emphasis on COVID-19.


2017 ◽  
Vol 2 (1) ◽  
Author(s):  
Paige Mason

The main message is clear: women are not making it to the top in any profession, anywhere in the world, and the field of prehospital and academic medicine is not immune. Whether in the public or private sphere, from the highest levels of government decision-making to common households, women continue to be denied equal opportunity with men


Author(s):  
Lucianna Benincasa

In this qualitative study of school discourse on national day commemorations, focus is on the "social creativity strategies" through which group members can improve their social identity. Discourse analysis was carried out on thirty-nine teachers' speeches delivered in Greek schools between 1998 and 2004. The speakers scorn rationality and logic, stereotypically attributed to "the West" (a "West" which is perceived not to include Greece), as cold and not human. The Greeks' successful national struggles are presented instead as the result of irrationality. They claim irrationality to be the most human and thus the most valuable quality, which places Greece first in the world hierarchy. The results are further discussed in terms of their implications for learning and teaching in the classroom, as well as for policy and research.


Popular Music ◽  
1996 ◽  
Vol 15 (3) ◽  
pp. 259-273 ◽  
Author(s):  
Tony Langlois

On 29 September 1994, Cheb Hasni, the most renowned Rai singer living in Algeria, was gunned down outside his family's house in Gambetta, a quarter of the city of Waharan (Oran). He was one of many public figures (and some 50,000 others) who have been killed since the main opposition political party, the FIS (Islamic Salvation Front) was prevented from assuming power by the annulment of elections that they would have won in 1991. Like the most notable of Algeria's victims of violence, which include journalists, lawyers, doctors, television presenters and top policemen, Hasni represented a version of Algerian identity that some people clearly could not tolerate. Responsibility for his assassination has not been claimed, but the manner of his death was identical to others carried out by the armed faction of the fundamentalist Islamic movement, the GIA (Armed Islamic Group). His death has possibly marked the demise of a genre of North African popular music known as Rai as it was produced in Algeria. Rai has been a particularly problematic idiom for Islamists and secularists alike. Both groups nurture distinct views of the place of Algeria, and Algerians in the world, and the role of Islam and liberal secularism in Algeria. Rai music constructs its own distinct trajectories linking local and global, ‘East’ and ‘West’, and, in this way, constitutes a distinct problem for Algerians, and indeed other North Africans today.


2020 ◽  
Vol 5 ◽  
Author(s):  
Syazana Fauzi

This study seeks to ascertain the state actor dynamics in Brunei’s healthcare policies from the perspectives of an Islamic system of governance, by first identifying the state actors, or institutions, involved in influencing, formulating and implementing Brunei’s healthcare policies. The ‘IGC Matrix’ is employed to establish the Islamic health ‘sets of expectations’ (SoEs), particularly in terms of prevention and treatment, and medical ethics, primarily derived from the Qur’ān and Prophet Muhammadﷺ’s Sunnah, in order to construct for this study a framework of reference. The SoEs are then compared against Brunei’s healthcare policies and activities to determine how much of the Islamic health SoEs are met. This study reveals that Brunei’s healthcare policies are largely motivated by non-Islamic inspirations, specifically by the World Health Organisation (WHO), but with numerous overlaps with Islamic demands. In other words, Brunei’s healthcare policies may be stemmed from a non-Islamic influence, but it does not necessarily mean that they are un-Islamic. And most, if not all, of Brunei’s healthcare policies demonstrate a top-down approach, where the state actors play a crucial role in shaping Brunei’s dynamical SoEs.


Significance The summit’s avowed aim was to renew the EU-US ‘Transatlantic partnership’, including committing to upholding the international rules-based order built around the UN. It called for cooperation with Russia in areas of common interest despite its repeated “negative behaviour”. Such strains include Russia’s opposition to appointing a new high representative for Bosnia. Impacts Vucic’s call for regular reports from the high representative recognises his legitimacy while asserting Serbian interest in BiH. Croatian President Zoran Milanovic’s support for the 1995 Dayton agreement weakens outside backing for Bosnian Croat separatism. The World Bank has left its growth forecast for BiH unchanged from January, provided vaccine roll-out accelerates.


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