Experimental study of the Ti-implant surfaces structured by the ytterbium-doped pulsed fiber laser

2021 ◽  
Vol 26 (2) ◽  
pp. 88-95
Author(s):  
A. I. Yaremenko ◽  
E. A. Zernitskaya ◽  
P. A. Zotov ◽  
Yu. Yu. Karlagina ◽  
E. E. Egorova ◽  
...  
Keyword(s):  
Fiber Laser ◽  
Dental Implants ◽  
Dental Implant ◽  
Laser Surface ◽  
Laboratory Animals ◽  
Promising Technique ◽  
Implant Surface ◽  
Surface Structuring ◽  
Pulsed Fiber Laser ◽  
The Stability

Relevance. Currently, there are several basic techniques for the dental implant surface structuring. Laser treatment is an extremely promising technique for the surface structuring. This technology allows creating regular implant surface without using chemicals and in just one technological step. The purpose was to present study aimed to compare and evaluate in vivo the stability and osseointegration of dental implants with 2 different surfaces structured by ytterbium-doped pulsed fiber laser operating at 1064 nm.Materials and methods. 60 dental implants were placed in the study. 2 types of dental implant surfaces, namely holes and parallel grooves, were created by the ytterbium laser operating at 1064 nm. A polished dental implant (without laser surface structuring) was also included in the experiment for comparison. The study was carried out on 15 laboratory animals (male rabbits, weight 3.5-4 kg). The implants were placed in the tibia. 4 implants with different surface types but of the same diameter and length were placed in each rabbit.Results. Laboratory animals were sacrificed 1.5 and 3 months after the surgery. The stability of the implants was assessed by RFA (Resonance Frequency Analysis), based on the registration of resonance electromagnetic oscillations of the implant and the surrounding bone when they are exposed to the electromagnetic field (Osstell ISQ). Also, nondecalcified bone blocks were histologically examined using a confocal laser scanning microscope (Carl Zeiss LSM 780) and histomorphometry was performed (BIC-index: Bone-to-implant contact). Bone blocks were prepared according to a special technique: they were soaked and embedded into the plastic and synthetic resin. The obtained blocks were cut into sections, 40-50 µm thick, and stained with toluidine blue.Conclusion. Laser surface structuring of the dental titanium implants is a promising technique. 59 in 60 (98.3%) implants were osseointegrated, there were no signs of inflammation in the bone tissue. The present results allow further studying of dental implants with various surface designs, structured by ytterbium laser.

scholarly journals Antimicrobial Effects of Three Different Treatment Modalities on Dental Implant Surfaces

2017 ◽  
Vol 43 (6) ◽  
pp. 429-436 ◽  
Author(s):  
Olav I. Larsen ◽  
Morten Enersen ◽  
Anne Karin Kristoffersen ◽  
Ann Wennerberg ◽  
Dagmar F. Bunæs ◽  
...  
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Er:Yag Laser ◽  
Antimicrobial Effect ◽  
Positive Control ◽  
Treatment Modalities ◽  
Bacterial Strains ◽  
Implant Surface ◽  
Antimicrobial Effects ◽  
Dental Implant Surface

Resolution of peri-implant inflammation and re-osseointegration of peri-implantitis affected dental implants seem to be dependent on bacterial decontamination. The aims of the study were to evaluate the antimicrobial effects of 3 different instrumentations on a micro-textured dental implant surface contaminated with an avirulent or a virulent Porphyromonas gingivalis strain and to determine alterations to the implant surface following instrumentation. Forty-five dental implants (Straumann SLA) were allocated to 3 treatment groups: Er:YAG laser, chitosan brush, and titanium curette (10 implants each) and a positive (10 implants) and a negative (5 implants) control. Each treatment group and the positive control were split into subgroups of 5 implants subsequently contaminated with either the avirulent or virulent P. gingivalis strain. The antimicrobial effect of instrumentation was evaluated using checkerboard DNA–DNA hybridization. Implant surface alterations were determined using a light interferometer. Instrumentation significantly reduced the number of attached P. gingivalis (P < .001) with no significant differences among groups (P = .310). A significant overall higher median score was found for virulent compared with avirulent P. gingivalis strains (P = .007); the Er:YAG laser uniquely effective removing both bacterial strains. The titanium curette significantly altered the implant surface micro-texture. Neither the Er:YAG laser nor the chitosan brush significantly altered the implant surface. The 3 instrumentations appear to have a similar potential to remove P. gingivalis. The titanium curette significantly altered the microstructure of the implant surface.

scholarly journals Preparation of Bioactive Titanium Surfaces via Fluoride and Fibronectin Retention

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Carlos Nelson Elias ◽  
Patricia Abdo Gravina ◽  
Costa e Silva Filho ◽  
Pedro Augusto de Paula Nascente
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Osteoblastic Cells ◽  
Acid Etching ◽  
Implant Surface ◽  
Force Microscopy ◽  
Dental Implant Surface ◽  
Before And After ◽  
Titanium Surfaces

Statement of Problem. The chemical or topographic modification of the dental implant surface can affect bone healing, promote accelerated osteogenesis, and increase bone-implant contact and bonding strength.Objective. In this work, the effects of dental implant surface treatment and fibronectin adsorption on the adhesion of osteoblasts were analyzed.Materials and Methods. Two titanium dental implants (Porous-acid etching and PorousNano-acid etching followed by fluoride ion modification) were characterized by high-resolution scanning electron microscopy, atomic force microscopy, and X-ray diffraction before and after the incorporation of human plasma fibronectin (FN). The objective was to investigate the biofunctionalization of these surfaces and examine their effects on the interaction with osteoblastic cells.Results. The evaluation techniques used showed that the Porous and PorousNano implants have similar microstructural characteristics. Spectrophotometry demonstrated similar levels of fibronectin adsorption on both surfaces (80%). The association indexes of osteoblastic cells in FN-treated samples were significantly higher than those in samples without FN. The radioactivity values associated with the same samples, expressed as counts per minute (cpm), suggested that FN incorporation is an important determinant of thein vitrocytocompatibility of the surfaces.Conclusion. The preparation of bioactive titanium surfaces via fluoride and FN retention proved to be a useful treatment to optimize and to accelerate the osseointegration process for dental implants.

scholarly journals Human Periodontal Ligament Stem Cells Response to Titanium Implant Surface: Extracellular Matrix Deposition

Biology ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 931
Author(s):  
Guya Diletta Marconi ◽  
Luigia Fonticoli ◽  
Ylenia Della Della Rocca ◽  
Thangavelu Soundara Rajan ◽  
Adriano Piattelli ◽  
...  
Keyword(s):  
Stem Cells ◽  
Extracellular Matrix ◽  
Dental Implants ◽  
Dental Implant ◽  
Periodontal Ligament ◽  
Implant Surface ◽  
Periodontal Ligament Stem Cells ◽  
Matrix Deposition ◽  
Dental Implant Surface ◽  
The Impact

The major challenge for dentistry is to provide the patient an oral rehabilitation to maintain healthy bone conditions in order to reduce the time for loading protocols. Advancement in implant surface design is necessary to favour and promote the osseointegration process. The surface features of titanium dental implant can promote a relevant influence on the morphology and differentiation ability of mesenchymal stem cells, induction of the osteoblastic genes expression and the release of extracellular matrix (ECM) components. The present study aimed at evaluating the in vitro effects of two different dental implants with titanium surfaces, TEST and CTRL, to culture the human periodontal ligament stem cells (hPDLSCs). Expression of ECM components such as Vimentin, Fibronectin, N-cadherin, Laminin, Focal Adhesion Kinase (FAK) and Integrin beta-1 (ITGB1), and the osteogenic related markers, as runt related transcription factor 2 (RUNX2) and alkaline phosphatase (ALP), were investigated. Human PDLSCs cultured on the TEST implant surface demonstrated a better cell adhesion capability as observed by Scanning Electron Microscopy (SEM) and immunofluorescence analysis. Moreover, immunofluorescence and Western blot experiments showed an over expression of Fibronectin, Laminin, N-cadherin and RUNX2 in hPDLSCs seeded on TEST implant surface. The gene expression study by RT-PCR validated the results obtained in protein assays and exhibited the expression of RUNX2, ALP, Vimentin (VIM), Fibronectin (FN1), N-cadherin (CDH2), Laminin (LAMB1), FAK and ITGB1 in hPDLSCs seeded on TEST surface compared to the CTRL dental implant surface. Understanding the mechanisms of ECM components release and its regulation are essential for developing novel strategies in tissue engineering and regenerative medicine. Our results demonstrated that the impact of treated surfaces of titanium dental implants might increase and accelerate the ECM apposition and provide the starting point to initiate the osseointegration process.

scholarly journals Critical Role of Etching Parameters in the Evolution of Nano Micro SLA Surface on the Ti6Al4V Alloy Dental Implants

Materials ◽  
2021 ◽  
Vol 14 (21) ◽  
pp. 6344
Author(s):  
Pankaj Chauhan ◽  
Veena Koul ◽  
Naresh Bhatnagar
Keyword(s):  
Surface Topography ◽  
Dental Implants ◽  
Dental Implant ◽  
Ti6al4v Alloy ◽  
Alloy Surface ◽  
Acid Etching ◽  
Implant Surface ◽  
Dental Implant Surface ◽  
Etching Parameters ◽  
Cp Ti

The surface of dental implants plays a vital role in early and more predictable osseointegration. SLA (sandblasted large grit and acid-etched) represents the most widely accepted, long-term clinically proven surface. Primarily, dental implants are manufactured by either commercially pure titanium (CP-Ti) or Ti6Al4V ELI alloy. The acid etch behavior of CP-Ti is well known and its effects on the surface microstructure and physicochemical properties have been studied by various researchers in the past. However, there is a lack of studies showing the effect of acid etching parameters on the Ti6Al4V alloy surface. The requirement of the narrow diameter implants necessitates implant manufacturing from alloys due to their high mechanical properties. Hence, it is necessary to have an insight on the behavior of acid etching of the alloy surface as it might be different due to changed compositions and microstructure, which can further influence the osseointegration process. The present research was carried out to study the effect of acid etching parameters on Ti6Al4V ELI alloy surface properties and the optimization of process parameters to produce micro- and nanotopography on the dental implant surface. This study shows that the Ti6Al4V ELI alloy depicts an entirely different surface topography compared to CP-Ti. Moreover, the surface topography of the Ti6Al4V ELI alloy was also different when etching was done at room temperature compared to high temperature, which in turn affected the behavior of the cell on these surfaces. Both microns and nano-level topography were achieved through the optimized parameters of acid etching on Ti6Al4V ELI alloy dental implant surface along with improved roughness, hydrophilicity, and enhanced cytocompatibility.

scholarly journals Current technology for identifying dental implants: a narrative review

2021 ◽  
Vol 45 (1) ◽  
Author(s):  
Mohammad Ali Saghiri ◽  
Peter Freag ◽  
Amir Fakhrzadeh ◽  
Ali Mohammad Saghiri ◽  
Jessica Eid
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Clinical Importance ◽  
Forensic Identification ◽  
Current Status ◽  
Main Body ◽  
Implant Surface ◽  
Digital Dentistry ◽  
Dental Implant Surface ◽  
Future Direction

Abstract Background This paper outlines the current status and mechanism for identifying dental implants, with emphasis on future direction and updated technology, and covers the existing factors influencing the identification of implant systems. Main body A search was performed on the current methods of identifying dental implants between January 2000 through Feb 2020 using online databases for articles published in English. The search was performed using the Google, Rutgers library, PubMed, MEDLINE databases via OVID using the following keywords: implant types identification by x-ray imaging, forensic identification of dental implant, surface types, threaded, non-threaded, software identification, recent technologies, which evaluated different methods in the identification of dental implants and its clinical importance for the dentist and the patient. Of the 387 articles found in initial search results, 10 met the inclusion criteria set for this review. These 10 studies were directly related to the identification of different implant systems. Many studies have indicated identifying dental implants as problematic due to many confounding factors, and the difficulty in finding the specific parts for the dental implant itself. The contribution of digital dentistry is critical. Factors like increasing number of implant manufacturers, dental tourism, and cost, make it difficult to detect and match dental implants by dentists during the chairside time. Conclusion These factors give rise to the need for a new system to help clinicians in decision making. Artificial intelligence seems to have shown potential to help in this case. However, detailed regulatory mechanisms are still needed for diagnosis and analysis.

scholarly journals Plant-Derived Nanobiomaterials as a Potential Next Generation Dental Implant Surface Modifier

2021 ◽  
Vol 8 ◽  
Author(s):  
Jaison Jeevanandam ◽  
Michael K. Danquah ◽  
Sharadwata Pan
Keyword(s):  
Dental Implants ◽  
Dental Implant ◽  
Bone Cells ◽  
Implant Surface ◽  
Implant Materials ◽  
Synthetic Materials ◽  
Dental Implant Surface ◽  
Nanocarbon Materials ◽  
Ionic States ◽  
Physical And Chemical

Dental implants resemble synthetic materials, mainly designed as teeth-mimics to replace the damaged or irregular teeth. Specifically, they are demarcated as a surgical fixture of artificial implant materials, which are placed into the jawbone, and are allowed to be fused with the bone, similar to natural teeth. Dental implants may be categorized into endosteal, subperiosteal, and zygomatic classes, based on the placement of the implant “in the bone” or on top of the jawbone, under the gum tissue. In general, titanium and its alloys have found everyday applications as common, successful dental implant materials. However, these materials may also undergo corrosion and wear, which can lead to degradation into their ionic states, deposition in the surrounding tissues, as well as inflammation. Consequently, nanomaterials are recently introduced as a potential alternative to replace the conventional titanium-based dental implants. However, nanomaterials synthesized via physical and chemical approaches are either costly, non/less biocompatible, or toxic to the bone cells. Hence, biosynthesized nanomaterials, or bionanomaterials, are proposed in recent studies as potential non-toxic dental implant candidates. Further, nanobiomaterials with plant origins, such as nanocelluloses, nanometals, nanopolymers, and nanocarbon materials, are identified to possess enhanced biocompatibility, bioavailability and no/less cytotoxicity with antimicrobial efficacy at low costs and ease of fabrication. In this minireview, we present an outline of recent nanobiomaterials that are extensively investigated for dental implant applications. Additionally, we discuss their action mechanisms, applicability, and significance as dental implants, shortcomings, and future perspectives.

scholarly journals CLINICAL STUDIES OF THE STABILITY AND PROCESS OF OSTEOINTEGRATION OF DENTAL IMPLANTS DURING IMMEDIATE AND DELAYED IMPLANTATION

2021 ◽  
Vol 16 (4) ◽  
pp. 97-103
Author(s):  
Petr Grishin ◽  
Elena Kalinnikova
Keyword(s):  
Dental Implants ◽  
Clinical Studies ◽  
Alveolar Bone ◽  
Primary Stability ◽  
Implant Surface ◽  
Delayed Implantation ◽  
Clinical Observations ◽  
Osseointegrated Implants ◽  
Surface Microstructures ◽  
The Stability

Subject. Analysis of the literature confirms that there is a definite relationship between surface microstructure, implant geometry, thread design and primary stability, and osseointegration processes. To date, a sufficient number of works on direct and delayed implantation have accumulated. However, there is not enough convincing clinical data on the quantitative assessment of primary stability at different periods of the osseointegration process. Despite the existence of experimental and clinical observations, it seems impossible to make a definite judgment about the mechanism of such a relationship. This chapter presents clinical studies of the stability and osseointegration of dental implants when performing, according to the indications, in 414 patients of direct and delayed implantation using implant systems with different surface microstructures. Goal. Conduct clinical studies of quantitative indicators of stability and osseointegration of implants with different microstructure of the surface during direct and delayed implantation. Methodology. For the clinical study of primary stability and the process of osseointegration during direct and delayed implantation with immediate functional loading, implant systems with different surface microstructures were used: Alfa Bio, Mis, Astra-Tech, Dentium, Ostem, Antogher, and also Humana Dental with an innovative surface. Osseointegrated implants have been used to achieve a predictable treatment outcome in clinical cases with partial or complete adentia, as well as in the presence of single, included defects. Results. There were no significant differences in stability indicators at the time of implant placement in the alveolar bone, depending on the type of implant and the method of implantation. Conclusions. In the process of integration of the implant into the bone tissue at a later date, the indicators of stability and osseointegration improve. The relationship between the appearance of the implant surface, primary stability and the time of its adaptation was revealed.

scholarly journals Microbial Biofilm Decontamination on Dental Implant Surfaces: A Mini Review

2021 ◽  
Vol 11 ◽  
Author(s):  
Jagjit Singh Dhaliwal ◽  
Nurul Adhwa Abd Rahman ◽  
Long Chiau Ming ◽  
Sachinjeet Kaur Sodhi Dhaliwal ◽  
Joe Knights ◽  
...  
Keyword(s):  
Systematic Review ◽  
Dental Implants ◽  
Dental Implant ◽  
Titanium Implant ◽  
Electrochemical Treatment ◽  
Future Research ◽  
Antimicrobial Drugs ◽  
Implant Surface ◽  
Coating Materials ◽  
Microbial Biofilm

IntroductionAfter insertion into the bone, implants osseointegrate, which is required for their long-term success. However, inflammation and infection around the implants may lead to implant failure leading to peri-implantitis and loss of supporting bone, which may eventually lead to failure of implant. Surface chemistry of the implant and lack of cleanliness on the part of the patient are related to peri-implantitis. The only way to get rid of this infection is decontamination of dental implants.ObjectiveThis systematic review intended to study decontamination of microbial biofilm methods on titanium implant surfaces used in dentistry.MethodsThe electronic databases Springer Link, Science Direct, and PubMed were explored from their inception until December 2020 to identify relevant studies. Studies included had to evaluate the efficiency of new strategies either to prevent formation of biofilm or to treat matured biofilm on dental implant surfaces.Results and DiscussionIn this systematic review, 17 different groups of decontamination methods were summarized from 116 studies. The decontamination methods included coating materials, mechanical cleaning, laser treatment, photodynamic therapy, air polishing, anodizing treatment, radiation, sonication, thermal treatment, ultrasound treatment, chemical treatment, electrochemical treatment, antimicrobial drugs, argon treatment, and probiotics.ConclusionThe findings suggest that most of the decontamination methods were effective in preventing the formation of biofilm and in decontaminating established biofilm on dental implants. This narrative review provides a summary of methods for future research in the development of new dental implants and decontamination techniques.

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