ИСПОЛЬЗОВАНИЕ РАСТИТЕЛЬНЫХ АДАПТОГЕНОВ ПРИ ДЕФИЦИТЕ ЖЕЛЕЗА У КОРОВ

Author(s):  
N.I. YAROVAN ◽  
E.N. RYZHKOVA ◽  
Y.V. KARTAMYSHEVA

Представлены результаты изучения влияния растительных адаптогенов на основе облепихи крушиновидной, боярышника обыкновенного, рябины обыкновенной и каштана конского на уровень железа при его дефиците, оксидантно-антиоксидантный статус и молочную продуктивность коров, содержащихся в условиях промышленного комплекса. Были сформированы 5 групп животных по 10 голов. Животные I (контрольной) группы получали основной рацион (ОР) II ОР измельченные семена каштана конского 50 г на 1 голову в сутки III ОР измельченные семена каштана конского 30 г высушенные плоды рябины обыкновенной 20 г на 1 голову в сутки IV ОР цельнозамороженные плоды облепихи крушиновидной 200 г на 1 голову в сутки V ОР цельнозамороженные плоды облепихи крушиновидной 130 г высушенные плоды боярышника обыкновенного 40 г на 1 голову в сутки. В опытных группах II, III, IV и V обнаружено увеличение содержания железа в сыворотке крови к 20-му дню эксперимента на 87, 78, 41 и 58, соответственно. Наблюдалось постепенное снижение уровня свободно-радикального окисления к 30-му дню опыта у коров этих групп. Уровень малонового диальдегида (МДА) снизился на 37,5, 13,4, 20 и 20, соответственно. Увеличение среднесуточного удоя отмечено у коров, получавших комплекс растительных средств из семян каштана плодов рябины (на 7,4) и плодов облепихи плодов боярышника (на 7,5).The resalts of impact studies of plant-based adaptogens (sea-buckthorn, hawthorn, mountain ash and chestnut) on serum iron level in cows, oxidative-antioxidant status and milk production of cattle contained in the industrial complex were shown. 5 groups were formed with 10 animals each: 1st control group (I) - animals received the main diet (MD) 2nd group (II) - MD chestnut seeds (50 g per 1 animal) 3rd group (III) - MD chestnut seeds/ mountain ash (30 g/20 g per 1 animal) 4th group (IV) - MD sea-buckthorn fruits (200 g per 1 animal) 5th group (V) - MD sea-buckthorn fruits/ hawthorn fruits (130 g /40 g per 1 animal). In experimental groups II, III, IV и V, an increase in the content of iron in blood serum by the 20th day of the experiment by 87, 78, 41, 58, respectively, was shown. There was also a gradual decrease in the free radical oxidation level by the 30th day of the experiment in cows of experimental groups II, III, IV и V, the malondialdehyde level (MDA) decreased by 37.5, 13.4, 20, 20 respectively compared to the initial values. The highest average daily milk production was observed in cows receiving a complex of herbal remedies from chestnut seeds mountain ash fruits (an increase by 7.4) and sea-buckthorn fruits hawthorn fruits (an increase by 7.5).

2015 ◽  
Vol 15 (2) ◽  
pp. 185
Author(s):  
Goce Cilev ◽  
Živko Gacovski ◽  
Biljana Petrovska ◽  
Jovan Stojković

This paper shows the results of production and chemical compo­sition of cow’s milk on a farm MILKO-HF, Prilep, R. Macedonia with capacity of 100 cows of Holstein-Frisian breed divided into two groups (control and experimental). In control group I which was fed in a standard way of nutrition (ration used on the farm), average daily production of milk per cow ws 22.49 kg with the following chemical composition of milk: average daily content of milk fat is 3.75%, protein 3.57%, lactose 4.65%, nonfat dry matter 9.56% and total dry matter 13.31%. In experimental group II which were fed with the ration according to normatives, average daily production of milk per cow is 24.04 kg with the following chemical composition of milk: average daily content of milk fat is 3.99%, protein 3.57%, lactose 4.65%, non-fat dry matter 9.58% and total dry matter 13.57%. The obtained results show the increase in milk production for 1.55 kg-6.89% and better chemical composition of milk in the experimental group of cows. Thus, dry matter was increased from 13.31% to 13.57%-1.95%, milk fat content from 3.75% to 3.99%-6.4%, nonfat dry matter from 9.56% to 9.58%-0.21%, while the content of protein and lactose stayed on equal level. It was determined that the normed nutrition has influenced on production increase and better chemical composition of milk without unnecessary spent high level of nutrient i.e. nutrition of cows according to recommended normative.


2010 ◽  
Vol 1 (2) ◽  
pp. 183-188 ◽  
Author(s):  
S. Saxena ◽  
J. Sehgal ◽  
A. Puniya ◽  
K. Singh

Anaerobic fungi were orally dosed to lactating buffaloes to study their effect on the digestibility of a diet (composed of 50% wheat straw and 50% concentrate along with six kg maize green/animal/day), rumen fermentation patterns and milk production. Group I (control) was administered with fungus-free anaerobic broth, while group II and III were administered with Orpinomyces sp. C-14 or Piromyces sp. WNG-12 (250 ml; 3-5 days of growth/animal/ week), respectively. Milk production was higher in group II and III (8.42 and 8.48 kg/d) than in the control (8.03 kg/d) with virtually the same feed intake (i.e. 11.50 and 10.62 and 11.79 kg, respectively). There was an increase of 6% fat-corrected milk yield/animal/day in group II and III, respectively compared to the control. The milk fat was higher in the fungal culture administered groups than in the control group. The digestibility of dry matter, crude protein, neutral detergent fibre, acid detergent fibre, cellulose and digestible energy also increased significantly in group II and III. The pH and ammonia nitrogen were lower, whereas total volatile fatty acids, total nitrogen, trichloroacid precipitable nitrogen and number of zoospores/ml of rumen liquor were higher in group II and III when compared to the control. Hence, it can be stated that rumen fungi can be used as a direct-fed microbial in lactating buffaloes, to enhance the digestibility of wheat straw based diets leading to higher production.


2020 ◽  
Vol 21 (3) ◽  
pp. 117
Author(s):  
Mas Yedi Sumaryadi ◽  
Dadang Mulyadi Saleh ◽  
Aras Prasetiyo Nugroho ◽  
Nu'man Hidayat ◽  
Chomsiatun Nurul Hidayah

The application of oxytocin induction to milk production in relation to the performance of kids in dairy goats had been carried out in the "PEGUMAS" dairy goat farmer group Gumelar District, Banyumas. This activity aimed to increase milk production and kid performance through the induction of the hormone oxytocin in dairy goats. The approach method was designed in two stages: the first stage carried out the socialization activities and demonstration of techniques for applying IPTEKS, and the second stage applied hormonal technology in the form of oxytocin hormone induction in dairy goats. The material used was dairy goat parity I aged 1.5 - 2 years allocated into 2 groups of 10 individuals each. Group I was dairy goat experiment not induced with the oxytocin hormone as the control. Group II was dairy goat experiment induced with the oxytocin hormone at a dose of 1 ml (10 IU) intramuscularly before milking. Milk production was measured morning and evening as daily milk production in milliliters (ml). Milk was given to the kid of each parent. The kid's performance was measured based on the daily weight gain of the kid during the study. Overall, the application of science and technology could be adopted by farmers, and oxytocin-induced dairy goat milk production (503.2 ml) was significantly higher (P<0.05) than control (305.4 ml) with an increase of 64.77%, with a positive level of correlation (r = 0.45) and contributed 19.83% to the kids daily body weight gain.


2021 ◽  
Vol 62 (2) ◽  
pp. 112-118
Author(s):  
Ayşe Tuğba Kartal ◽  
Zeynep Çağla Mutlu

The aim of the present study was to evaluate the relationship between febrile convulsion, serum iron levels and whole blood parameters. This cross-sectional case-control study included patients aged 6 months-6 years-old brought to the department of pediatrics of Kütahya ParkHayat Hospital with febrile convulsions between January 2015 and December 2019. The patients were divided into two groups as: febrile with convulsions (study group; n= 47) and febrile without convulsions (control group; n= 35). Both groups were age and sex-matched. Some blood parameters such as mean serum iron, ferritin, Hb and MCV levels were used to compare the groups. Mean serum iron levels of the study and control groups were 33.7 ± 2.1 μg/dL and 56.3 ± 7.4 μg/dL (p<0.05), and serum ferritin levels were 27.3 ± 6.2 ng/mL and 31.1 ± 2.1 ng/ mL (p>0.05), respectively. Mean hemoglobin levels of the study and control groups were 10.6 ± 1.7 g/dL and 11.1 ± 1.4 g/dL (p <0.05), and mean MCV levels were 71.1 ± 1.2 fL and 73.2 ± 1.1 fL (p>0.05), respectively. In the light of the findings of this study, the low serum iron and ferritin levels may be reinforcing factors for developing febrile convulsion. However, multicentre studies with more patients are needed to reach a precise conclusion.


2009 ◽  
Vol 37 (06) ◽  
pp. 375-378 ◽  
Author(s):  
Z. Metcitoglu ◽  
M. Ulgen ◽  
E. Borum ◽  
E. Temizel ◽  
S. Kasap ◽  
...  

Summary Objective: The purpose of the study was to evaluate the results of routine haematological, serum iron and iron binding capacity analyses in cattle with Mycobacterium avium subsp. paratuberculosis (MAP) infection. Material and methods: Thirty-eight cows were included in the study. An ELISA for MAP, intradermal Johnin test and microscopic examination of the animals faecal smears for acid fast organisms were performed. According to the results 19 cows (4–8 years old) were found positive and 19 cows (4–7 years old) from the same herd were negative and served as control group. In all cows routine haematological values as well as serum iron level and iron binding capacity were evaluated. Results: When compared with control animals, routine haematological values including haematocrit, haemoglobin and erythrocyte counts were significantly (p < 0.05) lower in positive cows. Also serum iron level (p < 0.01) and iron binding capacity (p < 0.01) were significantly lower in positive cows than in the control group. Conclusion: As a result, these parameters can be important for the mechanism of the pathogenesis of paratuberculosis.


2021 ◽  
Vol 69 (1) ◽  
Author(s):  
Asmaa Alhusseiny Ahmed Alsharkawy ◽  
Ahmed R. Rezk

Abstract Background Community-acquired pneumonia is a major cause of death among children. Inadequate nutrition disrupts the immune system and increases the susceptibility to infections. We aimed to evaluate the association between vitamin D, serum zinc, and iron, and pneumonia. A case-control study was conducted at the outpatient clinic and emergency room of Children’s Hospital. Thirty-one patients with community-acquired pneumonia and 36 healthy children (control group) underwent serum sampling for vitamin D, zinc, and iron. Results Most patients had mild form (n = 17, 54.8%). All patients survived and were discharged. The serum iron level showed a non-significant difference between pneumonia and control groups (p ˃ 0.05). TIBC, vitamin D, and serum zinc were significantly lower in the patient group than the control group (P value = 0.04, < 0.001, and 0.03, respectively). Vitamin D deficiency was highly associated with the severity of pneumonia (P value = 0.008). Conclusion Adequate serum zinc and vitamin D levels may be protective against infection with community-acquired pneumonia in children aged from 2 months to 5 years old, but not iron.


2021 ◽  
Vol 29 (1) ◽  
pp. 29-32
Author(s):  
Farhana Rahman ◽  
Qazi Shamima Akhter ◽  
Nahid Yeasmin ◽  
Farhana Sultana ◽  
Sabira Tabassum ◽  
...  

Background: Hair loss is a worldwide problem with significant prevalence in the developed countries. Although many pathophysiological factors have been involved in the development of hair loss, its etiology is still unclear. Trace elements. Objective: To assess duration of hair loss with serum iron level in alopecia. Methods: This cross sectional study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during January 2017 to December 2017. Serum iron level was estimated by flame atomic absorption spectrophotometry of thirty five newly diagnosed hair loss patients aged 18 to 45 years were study group and thirty five ages, sex and BMI matched healthy subjects were control group. Both male and female was assessed by analyzing time. In this study, the duration of hair loss was 1 to 18 months. Duration of hair loss in study group was divided in two groups such as ≤2 months and >2 months. Patients were selected from Department of Dermatology and Venerology, Dhaka Medical College Hospital, Dhaka. For statistical analysis Unpaired Student’s‘t’ test, Chi square tests and Pearson’s correlation coefficient (r) tests were performed. Results: In this study, serum iron level showed negative correlation with the duration of disease in study group. Conclusions: From this study, it is concluded that serum iron deficiency is associated with duration of hair loss patients. J Dhaka Medical College, Vol. 29, No.1, April, 2020, Page 29-32


2020 ◽  
Vol 10 (1) ◽  
pp. e06-e06
Author(s):  
Parisa Mohammadi ◽  
Farid Azizi Jalilian ◽  
Hassan Ahmadinia ◽  
vida Sheikh

Introduction: Studies show that blood lead level (BLL) is higher in hemodialysis patients than in healthy people. Lead can disrupt iron metabolism and hemoglobin synthesis and therefore it is regarded as a cause of anemia. Objectives: This study investigated the relationship between BLL and anemia in end-stage renal disease (ESRD) undergoing maintenance hemodialysis Patients and Methods: This case-control study was conducted on 70 patients who had received hemodialysis at least for three months. The participants were selected randomly among eligible patients considering the inclusion and exclusion criteria. Based on their hemoglobin levels, the participants were divided into two groups, namely patients with anemia (case) and those without anemia (control). Results: The mean age of the participants in the case and control groups were 63.8±11.02 and 55.4±13.34 years, respectively. There were significant differences between two groups regarding hemoglobin, C-reactive protein (CRP) and erythropoietin (EPo) levels (P < 0.05). There was a significant correlation between hemoglobin and ferritin levels in the case group and between the length of dialysis and serum iron level in the control group without anemia (P < 0.001). Conclusion: Our results showed no correlation between BLL and anemia, however the BLL was higher in those undergoing long-term maintenance hemodialysis. Our findings require further investigation with larger studies.


Author(s):  
O. V. Dzhyhaliuk ◽  
H. I. Stepaniuk ◽  
N. V. Zaichko ◽  
S. I. Kovalenko ◽  
K. P. Shabelnyk

According to the literature the leading cause of mortality among the population of Ukraine are cardiovascular diseases, what incidence tripled over the past 25 years and today stands at801.6 in100 000. It necessitates a search for new chemical compounds, suitable for creating manufacturing with a better safety profile and a high degree of efficiency.The aim of the study was to describe the effect of 4-[4-oxo-4N-quinazoline-3- il] benzoic acid (PC-66), compared with kordaron on the processes of free radical oxidation, endothelial nitric oxide production and activity of marker enzymes cytolysis cardiomyocytes adrenaline myocardiodystrophy (AMD) in rats.The study was conducted on 28 nonlinear rats of both sexes (weight – 165–220 grams), divided into four groups: group I (n = 7) – intact rats; group II (n = 7) – rats with untreated AMD (control); group III (n = 7) – rats with AMD treated with entity PC-66 (10 mg/kg intraperitoneally (i/p)); Group IV (n = 7) – rats with AMD treated with kordaron (10 mg/kg, i/p).Research shown that the development of a pilot AMD in rats was characterized by increased free radical oxidation processes, depletion of antioxidant defense system (with decreased content of G-SH, activity of superoxide dismutase and glutathione peroxidase), oppression of endothelial NO production. The most expressive metabolic disturbances were registered in the acute period of AMD (as of 2nd day). The use of 4-[4-oxo-4N-quinazoline-3-il] benzoic acid (PC-66, 10 mg/kg, i/p) provided an expressive cardioprotective effect which was compared with kordaron (10 mg/kg, i/p) at various stages of AMD.The mechanisms of cardioprotective action 4-[4-oxo-4N-quinazoline-3-il] benzoic acid can be realized due to the stabilization of cellular and subcellular membranes (as evidenced by the dynamics of marker enzymes cytolysis cardiomyocytes in serum and reduction of TBA-reactive substances in the myocardium), increasing the efficiency of the antioxidant system and correction of cellular redox buffer (as evidenced by the increasing pool of reduced glutathione, glutathione peroxidase and superoxide dismutase activity increased) and anti-ischemic activity associated with increased activity of endothelial NO synthase in cardiac muscle.


2020 ◽  
Vol 3 (1) ◽  
pp. 42-27
Author(s):  
Madhukar Rajaram Wagh ◽  
Sunil Joshi

Background: Cholelithiasis is a common abdominal disorder resulting in increasing hospital admissions. About 10-12% of adults develop gallstones. Aim of this study was to find out any association of serum iron and ferritin levels in patients of cholelithiasis. Subjects and Methods: Present study was conducted at the department of surgery, tertiary care institute of for the period 1 year. For the study purpose 70 gall stone cases and 70 normal healthy matched controls were taken as study participants. After explaining about the study to the subjects, an informed consent will be obtained, followed by a detailed history with clinical examination with more emphasis on the parameters given below in outcome variable (ultrasonography finding, serum iron level, serum ferritin level, serum cholesterol). Results: The mean age in the case group (gallstones present) is 43.12 years, as compared to the control group the mean age is 41.05 years, The study shows in the case group 64% of patient was female and 36% was male and in the control group 76% of patient was female and 24% was male. In this study 46 (65.7%) patients with gallstones have the value of serum iron less than normal (normal value: >40 µg/dl). Our study shows, there are 35 female patients with gallstone disease who have serum iron levels below the normal value Most of the patients with gallstone disease whose serum iron levels are subnormal are females. Our study shows that the mean serum iron between cases and control was statistically significant p 0.05. There is no effect of anemia on serum cholesterol. In this study the mean serum cholesterol between cases and control was statistical insignificant (p>0.7)) In the case group, 20 of male and 36 of female patients have normal serum ferritin levels. The number of females having normal serum ferritin levels (in both case and control groups) is more. Conclusion: Gallstones are more prevalent in female population than males. Serum ferritin association is insignificant as it increases other condition with inflammation also. Low serum iron level associated with high risk of cholelithiasis as this may lead to super saturation of bile.


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