CLINICAL CHARACTERISTICS AND EVALUATION OF THE EFFECTIVE TREATMENT OF CUTANEOUS WARTS BY ELECTROSURGERY

2020 ◽  
pp. 25-29
Author(s):  
Anh Mai Ba Hoang ◽  
Duan Nguyen Duy ◽  
Cat Mai Thi Cam ◽  
Nga Le Thi Thuy ◽  
Phuong Nguyen Thi Thanh ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Wide Distribution ◽  
Healing Time ◽  
Common Disease ◽  
Clinical Form ◽  
Plantar Wart ◽  
Dermatology Clinic ◽  
Cutaneous Wart ◽  
Cutaneous Warts ◽  
Single Lesion

Background: Cutaneous wart is a common disease caused by the infection of Human Papillomavirus, this disease has diverse clinical characteristics and many different treatments. We conducted this study to evaluate the clinical features and the efficacy electrosurgery treatment. Methods: A total 75 patients was diagnosed with cutaneous wart and treated by electrosurgery method at Dermatology Clinic of Hue University of Medicine and Pharmacy Hospital. Results: The age has a wide distribution. The female/male ratio was nearly egal. Most patients had a single lesion. Plantar wart was predominate with 63.3%. After the procedure, 90.8% of patients had mild and moderate pain. The rate of post-operative bleeding was high 85.3%. In the first week, the dried wound was 64.2%. The average healing time was about 4 weeks. The infection rate was 11%. Conclusion: The most common clinical form was plantar wart; electrosurgery had many advantages but some disadvantages in wound healing related to heat damage. Keywords: cutaneous wart, electrosurgery, HPV.

Empirical and long-term therapy for endometriosis-associated pelvic pain

2021 ◽  
pp. 8-12
Author(s):  
I. V. Kuznetsova
Keyword(s):  
Literature Review ◽  
Medical Treatment ◽  
Pelvic Pain ◽  
Clinical Characteristics ◽  
Current Data ◽  
Diagnosis And Treatment ◽  
Term Therapy ◽  
Common Disease ◽  
Long Term Therapy

Endometriosis is a common disease, the diagnosis and treatment of which is still a matter of debate. One of the main symptoms of endometriosis -pelvic pain is a particular problem due to the difficulties in identifying the cause and the lack of sufficient effect from surgical and medical treatment. The literature review presents current data on the prevalence, clinical characteristics and methods of individualized therapy in patients with pelvic pain established or presumably associated with endometriosis.

scholarly journals Effectiveness of measles, mumps and rubella vaccine as immunotherapeutic agent for cutaneous viral warts

2020 ◽  
Vol 6 (3) ◽  
pp. 439
Author(s):  
Anupama Devi Wahengbam ◽  
Jeyakumari Jeevan ◽  
Sowmya Dogiparthi
Keyword(s):  
Clinical Studies ◽  
Single Agent ◽  
Complete Response ◽  
Mmr Vaccine ◽  
Rubella Vaccine ◽  
Immunotherapeutic Agent ◽  
Management Evaluation ◽  
Cutaneous Wart ◽  
Short Narrative ◽  
Cutaneous Warts

<p>Immunotherapy for management of cutaneous wart with measles, mumps and rubella vaccine (MMR) is a promising new modality of management. Evaluation of the same has been done by various studies over the years reporting its effectiveness. A literature search was done using PubMed and google scholar. This short narrative review documents the response rates in various clinical studies done till 2019 which have reported the efficacy of MMR vaccine as an immunotherapeutic agent which ranged from 26-84% graded as complete response which is complete clearance of the treated warts. These studies were performed for evaluating MMR vaccine as single agent or done in comparison with other therapeutic agents. The broad range of responses points to a need of doing further clinical studies which will substantiate the effectiveness of MMR vaccine in the treatment of cutaneous warts.</p>

scholarly journals Leptospirosis presented with erythema nodosum on four limbs: an unusual presenting

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Lotfollah Davoodi ◽  
Armaghan Kazeminejad ◽  
Hamed Jafarpour ◽  
Alireza Razavi
Keyword(s):  
Rare Case ◽  
Erythema Nodosum ◽  
Clinical Manifestations ◽  
Common Disease ◽  
Clinical Form ◽  
Case Presentation ◽  
Typical Form ◽  
Wide Range ◽  
Adipose Inflammation ◽  
Subcutaneous Adipose

Abstract Leptospirosis is a common disease between humans and animals characterized by a wide range of clinical manifestations. Erythema nodosum (EN) is a common clinical form of panniculitis or subcutaneous adipose inflammation caused by hypersensitivity responses to antigens, but the presence of EN in a subject with leptospirosis is a very rare case presentation. We will present a 42-year-old man with a headache, myalgia, nausea and rigid tender on the shin and both forearms, which was a typical form of EN lesions.

scholarly journals Endometriosis is an important cause of pelvic pain in adolescence

2014 ◽  
Vol 60 (6) ◽  
pp. 560-564 ◽  
Author(s):  
Marina de Paula Andres ◽  
Sergio Podgaec ◽  
Karina Belickas Carreiro ◽  
Edmund Chada Baracat
Keyword(s):  
Differential Diagnosis ◽  
Pelvic Pain ◽  
Clinical Characteristics ◽  
Chronic Pelvic Pain ◽  
Conventional Treatment ◽  
Tertiary Hospital ◽  
Ovarian Cysts ◽  
Common Disease ◽  
Important Differential Diagnosis ◽  
The University

Objective: despite endometriosis being a common disease, where early detection is key to preventing its progression, it is a condition often overlooked in adolescents. The aim of this study was to report the clinical characteristics of adolescent patients with endometriosis monitored in a tertiary hospital. Methods: a retrospective study of 394 patients undergoing surgery with a histological diagnosis of endometriosis at the Endometriosis Division of the Gynecology Department at the Hospital das Clínicas of the University of São Paulo Medical School from 2008 to 2013. 21 adolescents were included (aged under 21 years). Results: the age ranged from 17.95 ± 1.48 years, the average time for diagnostic confirmation was 2.96 ± 2.93 years, and the age at the onset of symptoms was 15.28 ± 3.03 years on average. The sites affected were ovarian (38%), peritoneal (47.6%) and retrocervical (23.8%). Dysmenorrhea was found in 80.9 % of adolescents (severe in 33.3% of cases) and chronic pelvic pain in 66.6%. Conclusion: endometriosis in adolescents is an important differential diagnosis from pelvic pain and ovarian cysts, mainly among those with no response to conventional treatment. The main forms of involvement are peritoneal and ovarian. Despite the onset of symptoms in adolescence and advances in imaging methods, the diagnosis of this disease is still delayed.

scholarly journals Clinical and Epidemiological Study of Vitiligo Patients at a Dermatology Service in Northern Brazil

10.3823/2576 ◽  
2018 ◽  
Vol 11 ◽  
Author(s):  
ALINE DE LIMA DIAS ◽  
Carla Andréa Avelar Pires ◽  
Alvaro Alves dos Santos Neto ◽  
Brenna Pinheiro Mota Brabo de Oliveira ◽  
Luana De Paula dos Santos da Silva ◽  
...  
Keyword(s):  
Female Gender ◽  
The State ◽  
World Population ◽  
State University ◽  
Clinical Form ◽  
Research Committee ◽  
Cross Sectional ◽  
Adult Age ◽  
Dermatology Clinic ◽  
Epidemiological Characteristics

Background: Vitiligo is an acquired hypomelanosis that affects between 0.5% and 4% of the world population, characterized by distinct acromic macules of various shapes and sizes, and may appear in any region of the skin. Worldwide, there are few publications on vitiligo that address epidemiological characteristics. Thus, the objective was to describe the clinical and epidemiological profile of patients with this condition at the State University of Pará’s Dermatology Clinic, in the city of Belém, Northern of Brazil. Methods and Findings: A cross-sectional descriptive study was performed, in which 180 medical records of patients treated at the State University of Pará’s Dermatology Clinic, from July 2000 to July 2014, were analyzed using a protocol consisting of variables related to the disease. The information obtained was organized in a database and submitted to descriptive and inferential statistical analysis. The study was approved by the ethics and research committee under the number 923.213. A predominance of the female gender (72.2%), of the adult age group (55%) was observed; without relation to family history (46.7%); without progression (58.3%); with a predominant clinical form of vitiligo of the generalized type (67.2%), being the common generalized one with the highest prevalence (57%). The most affected sites were head and neck (27.5%), and upper limbs (25.3%). Conclusions: This study revealed the characteristics of the vitiligo patient residing in the Amazon region, and patients were found to have a generalized clinical form, most of the patients achieved improvement of the lesions with the proposed treatment, and only a minority presented progression of the disease. It is concluded that vitiligo is a disease with great therapeutic difficulty, and it is emphasized the importance of an early diagnosis, since in the early stages is easier to resolve the disease.

scholarly journals Fatal severe community-acquired pneumonia: risk factors, clinical characteristics and medical errors of hospital patients

2020 ◽  
Vol 92 (3) ◽  
pp. 42-49 ◽  
Author(s):  
L. B. Postnikova ◽  
P. F. Klimkin ◽  
M. V. Boldina ◽  
A. L. Gudim ◽  
N. I. Kubysheva
Keyword(s):  
Risk Factors ◽  
Medical Errors ◽  
Medical Records ◽  
Clinical Characteristics ◽  
Community Acquired Pneumonia ◽  
Lung Damage ◽  
Common Disease ◽  
Strict Adherence ◽  
Late Treatment ◽  
Nizhny Novgorod Region

Community-acquired pneumonia (CAP) is the most common disease and potentially life-threatening infection in the worldwide. In the Nizhny Novgorod region, no analysis of the causes of mortality and medical errors of severe CAP patients. Aim. To analyze the patients structure who died severe CAP in hospitals of the Nizhny Novgorod region, to identify the leading risk factors, to assess the clinical characteristics of fatal severe CAP and medical errors according to medical records of patients from 20152016. Materials and methods. This was a retrospective study of medical records of 139 patients with fatal severe CAP from medical organizations of the Nizhny Novgorod region. The 72 patients died in 2015. The mortality rate from pneumonia was 67 cases in 2016. Results. The key predictors of the fatal severe CAP in patients of the Nizhny Novgorod region identified: socio-demographic status (men of working age, unemployed, smoking, alcohol and drug dependence), late treatment and hospitalization, tachypnea, hypotension, tachycardia, confusion, leukocytosis or leukopenia, thrombocytopenia, anemia, hyperglycemia, bilateral lung damage, pleural effusion, acute respiratory failure. The leading medical errors in fatal CAP were incorrect assessment of the severity of the patients condition, untimely CAP, non-monitoring of SpO2 on the first day of hospitalization, late transfer of patients to the intensive care unit, there was no influenza therapy, inadequate starting antibacterial therapy. Conclusion. The main ways to avoid or minimize medical errors and reduce the mortality of patients with TVP is strict adherence to clinical recommendations, active preventive measures, diagnosis and treatment of chronic diseases.

scholarly journals Ligation of the Intersphincteric Fistula Tract (LIFT) Technique in the Treatment of Complex Perianal Fistula: Experience of First 50 Cases

2020 ◽  
Vol 15 (1) ◽  
pp. 3-7
Author(s):  
Swapan Kumar Biswas ◽  
ASM Tanjilur Rahman ◽  
Muhammad Mofazzal Hossain ◽  
Saiful Islam Khan
Keyword(s):  
Tissue Injury ◽  
Surgical Techniques ◽  
Perianal Fistula ◽  
Healing Time ◽  
Good Choice ◽  
Fistula Tract ◽  
Common Disease ◽  
College Hospital ◽  
Recurrent Fistula ◽  
Intersphincteric Fistula

Perianal fistula is a common disease and surgery is the only treatment option. Many surgical techniques have been described. Ligation of intersphincteric fistula tract (LIFT) is a sphincter saving surgical technique in which fistula tract is ligated and excised through intersphincteric approach. The aim of study is to present our experience of first 50 LIFT procedures particularly healing rate, recurrence rate and complications from the procedure. This is a prospective observational study started from March 2018 on whom underwent LIFT procedure for primary complex perianal fistula of infective origin at Faridpur Central Hospital and Faridpur Medical College Hospital. In this study, 50 patients (42 male and 8 female) of average age of 39±7.6 years with complex fistula were included. The mean operative time was 34.7±5.67 minutes and most of the fistulas were transsphincteric variety (90%). Median wound healing time was 21.45±6.34 days for intersphincteric wound and 26.78±6.93 days for the external opening of the fistula. Mean follow up period was 10.5 months. Seven patients of our series developed recurrent fistula, making the overall success of 86%. None of the patient in our series developed incontinence. LIFT procedure has the advantage of preservation of anal sphincter, minimal tissue injury, shorter healing time, relatively easy to perform, and high success rate. It's a good choice for treatment of complex perianal fistula. Faridpur Med. Coll. J. Jan 2020;15(1): 3-7

scholarly journals Enthesitis Related Arthritis in a Longitudinal Southeast Asian Registry: High Prevalence of HLA-B27, Different Sacroiliitis Risk Factors and Less Common Drug-Free Remission

2021 ◽  
Vol 10 (4) ◽  
pp. 568
Author(s):  
Thaschawee Arkachaisri ◽  
Kai Liang Teh ◽  
Yun Xin Book ◽  
Sook Fun Hoh ◽  
Xiaocong Gao ◽  
...  
Keyword(s):  
Clinical Characteristics ◽  
Cox Regression ◽  
Age At Onset ◽  
Human Leukocyte ◽  
Common Disease ◽  
Hla B27 ◽  
Significance Level ◽  
Enthesitis Related Arthritis ◽  
Joint Deformity ◽  
Kaplan Meier

Objective. To describe the clinical characteristics, predictors and treatment of children with Enthesitis Related Arthritis (ERA) in a Singapore longitudinal cohort over 11 years. Methods. ERA patients were recruited from our registry (2009–2019). Nonparametric descriptive statistics including median (interquartile range, IQR) were used to describe data. Kaplan–Meier survival and logistic/Cox regression analyses were used to estimate the probabilities and determine predictors of clinical variables, respectively. The significance level was set at <0.05. Results. One hundred and forty-six ERA patients (87% male, 82% Chinese) were included. Median onset age was 11.9 years (IQR 9.4–14.0) and median disease duration was 4.9 years (IQR 2.6–8.3). Family history of Human Leukocyte Antigen (HLA)-B27 associated diseases was positive in 7.5%. Acute uveitis occurred in 3.4%. Oligoarthritis was present in 89.7%. Hip, knee and ankle joints were among the most common joints involved. One-fourth had enthesitis at diagnosis (Achilles tendon entheses, 82.9%). Sacroiliitis occurred in 61%. Probabilities of sacroiliitis development were 0.364, 0.448 and 0.578 at 1, 2 and 5 years after onset, respectively. Negative HLA-B27, female, older age at onset and hip arthritis at diagnosis were associated with shorter time for sacroiliitis development (p = 0.001–0.049). Methotrexate (MTX) remained the most common disease modifying anti-rheumatic drug (DMARD) used (77.4%). However, 77.9% required anti-TNF (aTNF) therapy secondary to MTX failure. Among MTX-treated sacroiliitis patients, 85.3% failed, requiring aTNF, as compared to 63.2%patients without axial disease. Longer duration to diagnosis (p = 0.038) and MTX use (p = 0.007) predicted aTNF therapy. None had joint deformity. Conclusions. This study underscores differences in ERA clinical characteristics, predictors and treatment responses. Our ERA population had many unique findings but good functional outcomes.

scholarly journals Efficacy and Tolerability of Topical Green Tea Extract (Polyphenon E) Application in a “Therapy-Resistant” Plantar Wart

2018 ◽  
Vol 10 (2) ◽  
pp. 127-132 ◽  
Author(s):  
Giancarlo Meloni ◽  
Massimo Milani
Keyword(s):  
Metatarsal Head ◽  
Initial Visit ◽  
Local Tolerability ◽  
Present Treatment ◽  
Plantar Wart ◽  
Polyphenon E ◽  
Therapeutic Problem ◽  
Tea Extract ◽  
Cutaneous Warts ◽  
Plantar Warts

Plantar warts account for 30% of all cutaneous warts. These lesions could be very painful, especially if the lesion is located over pressure sites such as the metatarsal head. Plantar wart treatment remains a challenging therapeutic problem. A 67-year-old immunocompetent nonsmoking man presented with a large mosaic plantar wart on his right foot. The lesion had been present for 5 years. Several cryotherapy sessions (a total of 6 procedures) had been performed with no success. The lesion was therefore treated with a 5-fluorouracil (5-FU) regimen and then with a topical combination of 5-FU and salicylic acid, but also these approaches failed. At the initial visit, a large (16 cm2) mosaic wart lesion was present. Treatment with topical Polyphenon E, 10%, twice daily was prescribed and started. After 3 months of treatment, the lesion completely disappeared. Interestingly, no curettage or mechanical pickling of the hyperkeratotic parts of the lesion were performed before the start of the treatment. Local tolerability was evaluated as very good by the patient.

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