scholarly journals The relationship between maternal vitamin D level with infants’ birth-weight, height and head circumference at birth

2020 ◽  
Vol 5 (1) ◽  
pp. e17-e17
Author(s):  
Arezoo Moradi ◽  
Fatemeh Sharif Zadeh
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Head Circumference ◽  
Normal Vaginal Delivery ◽  
Blood Levels ◽  
Significant Difference ◽  
The Mean ◽  
The Relationship ◽  
Normal Head

Introduction: Prevalence of vitamin D deficiency has been reported from all over the world since lower levels of vitamin D has been one of word’s problem in the 21st century; especially pregnant women are the most prominent one. Objectives: This study aims to investigate the relationship between mothers’ vitamin D level with infants’ birth-weight and head circumference. Patients and Methods: A cross-sectional study was conducted in the department of obstetrics and gynecology of Akbarabadi hospital during 2017-2018. Regarding two groups, infants’ three main characteristics including their weight, head circumference and height were studied. Results: The mean blood levels of vitamin D in mothers with normal-born neonates were 15.23 ± 7.14 (ng/ mL) and in the mothers who gave birth to low-birth weight were 10.02 ± 8.06 (ng/mL), which was significantly lower than the mothers of normal-weight infants (P=0.018). The mean blood levels of vitamin D in mothers who gave birth to a normal head circumference neonate were 16.07 ± 8.1 (ng/mL) and in mothers with infants’ head circumference of less than 33 cm, was 9.87 ± 7.57 (ng/mL), which was significantly lower from mothers of normal-head circumference infants (P=0.007). The serum levels of vitamin D in mothers with normal-height infants were 14.74 ± 7.52 (ng/mL) and in the mothers with a height of less than 47 cm were 15.17 ± 7.91 (ng/mL), that does not suggest any significant difference (P=0.341). The mean serum vitamin D level in mothers who had normal vaginal delivery was lower than those with cesarean delivery, however there was no significant difference (P=0.174). Conclusion: Nutrition improvement and prescribing vitamin D supplements can positively be effective in the way of curbing low-birth weight infants. Moreover, Exposure to sunlight and letting rays strike skin is essential for maintaining a healthy vitamin D status for girls and women.

scholarly journals Clinical Factors That Affect the Relationship between Head Circumference and Brain Volume in Very-Low-Birth-Weight Infants

2018 ◽  
Vol 29 (1) ◽  
pp. 104-110 ◽  
Author(s):  
Yukako Kawasaki ◽  
Taketoshi Yoshida ◽  
Mie Matsui ◽  
Akiko Hiraiwa ◽  
Satomi Inomata ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Head Circumference ◽  
Very Low Birth Weight ◽  
Brain Volume ◽  
Clinical Factors ◽  
Low Birth Weight Infants ◽  
The Relationship

scholarly journals Changes in the physiological parameters of newborns in the first one hour of life

2019 ◽  
Vol 6 (4) ◽  
pp. 1533
Author(s):  
Shasidhar Reddy Y. ◽  
Abdul Mohid Syed ◽  
Gangadhar B. Belavadi
Keyword(s):  
Heart Rate ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Oxygen Saturation ◽  
Mode Of Delivery ◽  
Physiological Parameters ◽  
Peripheral Oxygen Saturation ◽  
College Hospital ◽  
Significant Difference ◽  
The Mean

Background: The transition from a fetus to a newborn is the most complex adaptation that occurs in human experience. This study assessed three physiological parameters viz. temperature (core and peripheral), oxygen saturation and heart rate so as to avoid the delay in normal transitional adaptation.Methods: This cross-sectional observational study was done at Narayana Medical College Hospital, Nellore, Andhra Pradesh, India. A total of 150 neonates born from June 2017 to February 2018 were monitored for heart rate, oxygen saturation, core and peripheral temperature from birth to 60 minutes.Results: Most of the mother’s (45.33%) were aged between 22 to 25 years and the mean age was 23.75±3.64 years. History of consanguineous marriage was noted in 33.33%. The mode of delivery was vaginal in 70.67% of the babies. The mean gestational age was 38.74±1.36 weeks. The birth weight among 62% of the babies was between 2.5 to 3.49 Kgs and mean birth weight was 2.81±0.49 kgs. The meconium stained liquor and requirement of resuscitation was noted in 9.33% and 10.67% respectively.Conclusions: Significant difference was noted with regard to heart rate in babies with active resuscitation, low birth weight (<2.5 kg), meconium stained liquor and warmer care compared to normal babies. There was variation in oxygen saturation in babies who required resuscitation and warmer care, and those who had low birth weight. The mean peripheral and core temperature were different in babies with abdominal care compared to warmer care.

scholarly journals Vitamin D and T- regulator cells are not independent factors for RDS in premature neonates

2021 ◽  
Vol 61 (4) ◽  
pp. 192-7
Author(s):  
Putri Maharani Tristanita Marsubrin ◽  
Agus Firmansyah ◽  
Rinawati Rohsiswatmo ◽  
Yuditiya Purwosunu ◽  
Zakiudin Munasir ◽  
...  
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Vitamin D Deficiency ◽  
Umbilical Cord ◽  
Very Low Birth Weight ◽  
Treg Cells ◽  
High Morbidity ◽  
Premature Neonates ◽  
The Mean

Background The high morbidity and mortality of premature neonates remain significant problem in Indonesia with respiratory distress syndrome (RDS) as one of the most common problem. Vitamin D plays  an important role in lung maturity. Vitamin D deficiency causes epithelial cell inflammation, leading to a higher risk of RDS. Previous studies suggest that T regulatory cells (Treg) in inflammatory diseases, such as RDS in neonates, are possibly linked to vitamin D deficiency. Objective To determine the role of vitamin D on RDS and Treg cells in very premature or very low birth weight neonates. Methods A prospective cohort study conducted on premature neonates in Neonatology Division, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Jakarta, Indonesia. Umbilical cord blood samples were collected to evaluate total vitamin D 25-OH levels and Treg cells. Subjects with RDS were evaluated until the end of the observation period. Results The mean umbilical cord vitamin D level was 15.79 (SD 6.9) ng/mL, and 53% of the subjects were found to be deficient. As much as 65.1% of neonates had RDS. The mean Treg level was 11.38 (SD 2.45)%. No significant correlation was observed between vitamin D level and the occurrence of RDS (RR 0.87; 95%CI 0.56 to 1.34; P=0.53); vitamin D level and the dysregulation of Treg cells (RR 1.30; 95%CI 0.76 to 2.21; P=0.31) as well as between Treg dysregulation and RDS (RR 1.11; 95%CI 0.70 to 1.75; P=0.64). However, we found that RDS group had a lower gestational age and higher presentation of dysregulation Treg. Conclusion In very premature or very low birth weight neonates, no association between occurence of RDS and vitamin D deficiency as well as Treg cell dysregulation.

Does prenatal exposure to vitamin D-fortified margarine and milk alter birth weight? A societal experiment

2014 ◽  
Vol 112 (5) ◽  
pp. 785-793 ◽  
Author(s):  
Camilla B. Jensen ◽  
Tina L. Berentzen ◽  
Michael Gamborg ◽  
Thorkild I. A. Sørensen ◽  
Berit L. Heitmann
Keyword(s):  
Vitamin D ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Prenatal Exposure ◽  
Fetal Growth ◽  
School Children ◽  
School Health ◽  
Health Record ◽  
Copenhagen School ◽  
The Mean

The present study examined whether exposure to vitamin D from fortified margarine and milk during prenatal life influenced mean birth weight and the risk of high or low birth weight. The study was based on the Danish vitamin D fortification programme, which was a societal intervention with mandatory fortification of margarine during 1961–1985 and voluntary fortification of low-fat milk between 1972 and 1976. The influence of prenatal vitamin D exposure on birth weight was investigated among 51 883 Danish children, by comparing birth weight among individuals born during 2 years before or after the initiation and termination of vitamin D fortification programmes. In total, four sets of analyses were performed. Information on birth weight was available in the Copenhagen School Health Record Register for all school children in Copenhagen. The mean birth weight was lower among the exposed than non-exposed children during all study periods (milk initiation − 20·3 (95 % CI − 39·2, − 1·4) g; milk termination − 25·9 (95 % CI − 46·0, − 5·7) g; margarine termination − 45·7 (95 % CI − 66·6, − 24·8) g), except during the period around the initiation of margarine fortification, where exposed children were heavier than non-exposed children (margarine initiation 27·4 (95 % CI 10·8, 44·0) g). No differences in the odds of high (>4000 g) or low ( < 2500 g) birth weight were observed between the children exposed and non-exposed to vitamin D fortification prenatally. Prenatal exposure to vitamin D from fortified margarine and milk altered birth weight, but the effect was small and inconsistent, reaching the conclusion that vitamin D fortification seems to be clinically irrelevant in relation to fetal growth.

scholarly journals Catch-up growth and nutritional status of preterms born at a Ugandan tertiary hospital: An Observational study.

2020 ◽  
Author(s):  
Flaviah Namiiro ◽  
Anthony Batte ◽  
Joseph Rujumba ◽  
Nicolette Nabukeera ◽  
Ian Munabi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Nutritional Status ◽  
Head Circumference ◽  
Maternal Age ◽  
Anthropometric Measurements ◽  
World Health ◽  
Z Scores ◽  
The Mean ◽  
Catch Up

Abstract Introduction Advances in neonatal care have led to the increasing survival of preterm/low birth weight infants worldwide. However, there is limited data on growth outcomes following preterm births especially in low and middle income countries. We assessed the catch-up growth, nutritional status and associated factors of Ugandan children who were born preterm/ low birth weight at Mulago National Referral Hospital.Methods: We enrolled children aged 22-38 months who had been born as preterm with low birth weight and their mothers. Participants were identified and recruited from the follow up clinic for preterm babies discharged from the neonatal unit of Mulago Hospital. Anthropometric measurements for mothers and children were taken. The children’s weight for height z-scores, height for age z-scores, weight for age z-scores, head circumference and mid upper arm circumference (MUAC) were taken and the mothers’ body mass index were generated based on the World Health Organization standards. Results: Of the 251 children and mother pairs recruited, 129 children (51.4%) were male, the mean age was 29.7 months (SD±4.5) and the mean maternal age was 29.9 (SD±5.3). 101(40.1%) of the children enrolled had attained catch up growth on the normal anthropometric measurements for their age. Among the participants, the prevalence of wasting, underweight and stunting was: 8 (3.2%), 36 (14.4%) and 106 (42.2%) respectively. Factors associated with stunting were male sex (AOR 2.36, 95% CI 1.42 to 3.95); p=0.001), maternal age ≤ 25years: AOR 2.27 (95%CI 1.13, 4.52); p= 0.020, and maternal height <150cm: AOR 5.57(95%CI 1.90, 16.94); P=0.002. Associations with underweight in the children were; birth weight ≤1500 gms: AOR 2.38(95%CI 1.14, 4.95); p=0.020 and post-natal hospitalization of more than 14 days: AOR 5.93(95%CI 1.96, 17.90); p=0.002. For 246 (98.8%) participants, MUAC was normal (≥ 12.5 cm) and for 216 (86.8%) the head circumference was within normal range for age.Conclusion: Of the children born preterm/LBW 40.1% of the participants had attained the expected catch up growth at 2 to 3 years of age, 42.2% were observed to be stunted while 14.4% were underweight both higher than the national levels. Targeted interventions are specifically needed for children born with very low birth weight, those requiring long postnatal hospitalization, males and those born to short or young mothers.

scholarly journals Morbidity and mortality pattern of very low birth weight infants admitted in SNCU in a South Asian tertiary care centre

2018 ◽  
Vol 5 (3) ◽  
pp. 720 ◽  
Author(s):  
Kabilan S. ◽  
Mekalai Suresh Kumar
Keyword(s):  
Mechanical Ventilation ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Gestational Age ◽  
Very Low Birth Weight ◽  
Tertiary Care ◽  
Morbidity And Mortality ◽  
Normal Vaginal Delivery ◽  
Vlbw Infants ◽  
The Mean

Background: Around 4-8% of all live births are very low birth weight (VLBW) infants.  In India currently 8 million VLBW infants are born each year which constitutes 40% of global burden the highest for any country. The present study was done to determine frequency of disease, complications, survival rate and risk factors for morbidity and mortality in VLBW babies.Methods: Between October 2016 and September 2017, we did a cross-sectional retrospective study at level three SNCU with >98% inborn admissions and about more than 10000 deliveries per year. The American Academy of Pediatrics protocol for neonatal resuscitation was followed for the management of VLBW. Data were entered in predetermined proforma and statistical analysis was done.Results: There were 154 registered cases of VLBW [75 females (48.7%) and 79 males (51.3%)]. The mean birth weight=1.198 (SD=0.211). The mean gestational age in weeks was 31.9 (SD=3.095).  Majority of them were in the gestational age 33-36 weeks (n=68, 44.2%), small for gestational age (n=89, 57.8), delivered through normal vaginal delivery (n=95, 61.7%), singletons (n=126, 81.8%), inborn (n=152, 98.7%), maternal age between 21-30 (n=95, 61.6%), clear amniotic fluid (n=137, 89%), on antenatal steroids (n=59, 38.3%), maternal disease were present in 55 mothers (33%) and gestational hypertension being more common (n=14, 9.6%). Majority of babies had Respiratory Distress Syndrome (n=56, 33.6%), birth asphyxia (n=54 32.4%) and sepsis (n=46, 27.6%). Mortality of 40.3% (n=62) observed in present study. Forty three babies with RDS, twenty babies with asphyxia and eight babies with sepsis expired.Conclusions: Multiple regression analysis with adjusted estimates of odds ratio showed that very low birth weight, low Apgar score at 5 minute, intubation and mechanical ventilation were predictors of outcome of VLBW babies. Birth weight and mechanical ventilation were significant predictors of the outcome of ELBW babies.

Free thyroxin measured in dried blood spots from normal, low-birth-weight, and hypothyroid neonates

1991 ◽  
Vol 37 (12) ◽  
pp. 2114-2117 ◽  
Author(s):  
Françoise Lemonnier ◽  
Joëlle Masson ◽  
Dominique Laroche ◽  
Josette Travert ◽  
Georges Travert
Keyword(s):  
Birth Weight ◽  
Linear Regression ◽  
Low Birth Weight ◽  
Multiple Linear Regression ◽  
Gestational Age ◽  
Neonatal Screening ◽  
Dried Blood Spots ◽  
Blood Spots ◽  
Significant Difference ◽  
The Mean

Abstract We have adapted a new radioimmunoassay for free thyroxin (FT4) measurement in dried blood spots for use in neonatal screening for hypothyroidism. The method is easy, fast, and cheap. Within-assay and between-assay CVs are respectively 9.6% and 13.2%. In 997 neonates three days postpartum with normal thyrotropin concentrations, the mean FT4 concentration was 27.2 pmol/L (SD 7.3 pmol/L). There was no significant difference in mean FT4 concentration between boys and girls. FT4 concentrations increased linearly with birth weight or with gestational age, as expressed by multiple linear regression: FT4 (pmol/L) = 0.0016 birth weight (g) + 0.6931 gestational age (weeks) − 4.8772. Only gestational age significantly affected the FT4 value. For five hypothyroid infants tested on day three postpartum, FT4 values were all below the 1st percentile of values from healthy neonates. Thus, when the neonatal concentration of thyrotropin is above normal, FT4 measured in the same sample can provide a reliable earlier diagnosis of hypothyroidism.

scholarly journals Anthropometric outcome of extremely low birth weight and very low birth weight newborn at 12 months of corrected age associated with prenatal risk factors

2019 ◽  
Vol 6 (6) ◽  
pp. 2242
Author(s):  
Balai Ch. Karmakar ◽  
Ramesh Ch. Kalder
Keyword(s):  
Risk Factors ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Head Circumference ◽  
Extremely Low Birth Weight ◽  
Perinatal Risk Factors ◽  
Perinatal Risk ◽  
Low Birth Weight Babies ◽  
The Mean ◽  
Weight For Age

Background: Advancement of skill, technology and perinatal medicine has led to improve survival of low birth weight babies during the last few decades but they have reported high incidence of growth failure during infancy and early childhood. The objective of the study was to find out the influence of perinatal risk factors on anthropometric outcome.Methods: A prospective cohort study conducted on 143 ELBW and VLBW babies admitted in Sick Newborn Care Unit (SNCU and PICU) of North Bengal Medical College and Hospital (NBMC), Darjeeling, West Bengal from 2016 to 2017 and discharged babies were followed up.Results: Total 143 neonates were studied at NBMC among male 82(57.3%) and female 61(42.7%), 95 were AGA and 48 were SGA babies. Significant positive correlations were found among birth weight, gestational age, perinatal infection (p<0.001). The mean weight for age (Mean±SD) was 7.615±1.1092 kg with median 7.8 kg. The mean length for age (Mean±SD) was 72.6±3.74 cm with median 73 cm. The mean head circumference for age (Mean±SD) was 42.5±2.12 cm median 43 cm. Adverse neonatal outcome associated with CRIB II score ≥10. Total CRIB II score with parameters of growth (<-2 Z score) like weight for age, length for age, weight for length and head circumference for age shows significant correlation (p<0.001).Conclusions: Perinatal risk factors are important determinant for future anthropometric outcome in very low and extremely low birth weight babies. They should be identified, and appropriate measures should be taken to achieve good outcome.

scholarly journals Development of Symphysio Fundal Height Curve

2017 ◽  
Vol 32 (1) ◽  
pp. 20-24
Author(s):  
Chowdhury Taslima Nasrein ◽  
Ferdousi Begum ◽  
Jaglul Haider Khan ◽  
Novera Islam ◽  
Zahangir Alam
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Gestational Age ◽  
Cross Sectional ◽  
Medical College ◽  
Gestation Age ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship

Objective: To Develop a symphysio fundal height(SFH) curve of pregnant women from 20 weeks of pregnancy onwards; and to find out the relationship of fundal height with different variables. Methodology: A cross-sectional hospital based study was conducted from 1st january 2010 to 31st December 2010 on 159 patients with gestation age less than 20 weeks at entry in the OPD of Department of Obstetric and Gynaecology, Shaheed Suhrawardy Medical College & Hospital, Shere-e Bangla Nagar, Dhaka,Bangladesh. All the patients were followed up till delivery. Results: The measurements of SFH obtained on the basis of 10, 50th and 90th percentiles and the rate of growth of SFH was approximately 5 mm per week from 24 weeks to 36 weeks and thereafter it was 5-6 mm per week till 40 weeks.Patients with higher socioeconomic class had higher symphysio fundal height.SFH is less in younger subjects. SFH increases with increased height,weight,gestational age,gravidity of mothers and birth weight of the baby.Multiparous was predominant and more than one third (34.6%) of the study patients height belonged to 1.51 - 1.60 meters. The mean±SD gestational age was 39.2±1.4 weeks with range from 28 to 41 weeks. Low birth weight was found 17.0% and the mean±SD birth weight was 2.8±0.4 kg with range from 1.9 to 3.8 kg. Bangladesh J Obstet Gynaecol, 2017; Vol. 32(1): 20-24

scholarly journals Relationship of Cord Blood Immunoglobulin E and Maternal Immunoglobulin E with Birth Order and Maternal History of Allergy in Albanian Mother/Neonate Pairs

2017 ◽  
Vol 5 (6) ◽  
pp. 751-756
Author(s):  
Hatixhe Latifi-Pupovci ◽  
Violeta Lokaj-Berisha ◽  
Besa Lumezi
Keyword(s):  
Cord Blood ◽  
Birth Order ◽  
Immunoglobulin E ◽  
Blood Levels ◽  
Significant Difference ◽  
History Of ◽  
Study Population ◽  
The Mean ◽  
Relationship Of ◽  
The Relationship

BACKGROUND: Previous studies reported that familial factors such as birth order and mothers atopy might influence cord blood levels and development of allergies.AIM: The aim of the study was to evaluate the relationship of cord blood IgE and maternal IgE with birth order and mothers history of allergy in Albanian mother/neonate pairs.MATERIAL AND METHODS: Study population represented 291 mother-infant pairs. Mothers were interviewed with a questionnaire for personal history of allergy and pregnancy history whereas serum IgE levels were determined using sandwich IRMA assay.RESULTS: The mean level of cIgE in neonates with detectable levels was 1.59 (n = 78). No significant difference in means of cIgE was found between first born and later born neonates (p = 0.232) and between neonates of mothers with a negative and positive history of allergy (p = 0.125). Also, no significant difference was found between means of mIgE by birth order, whereas there was a significant difference of mIgE between mothers with and without a history of allergy (p = 0.01). In a group of neonates with detectable cIgE levels, maternal IgE levels were moderately correlated with cIgE levels.CONCLUSION: Cord blood IgE is not affected by birth order and mothers history of allergy, whereas mothers IgE are affected by the history of allergy but not by birth order.

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