scholarly journals Relationship of Cord Blood Immunoglobulin E and Maternal Immunoglobulin E with Birth Order and Maternal History of Allergy in Albanian Mother/Neonate Pairs

2017 ◽  
Vol 5 (6) ◽  
pp. 751-756
Author(s):  
Hatixhe Latifi-Pupovci ◽  
Violeta Lokaj-Berisha ◽  
Besa Lumezi

BACKGROUND: Previous studies reported that familial factors such as birth order and mothers atopy might influence cord blood levels and development of allergies.AIM: The aim of the study was to evaluate the relationship of cord blood IgE and maternal IgE with birth order and mothers history of allergy in Albanian mother/neonate pairs.MATERIAL AND METHODS: Study population represented 291 mother-infant pairs. Mothers were interviewed with a questionnaire for personal history of allergy and pregnancy history whereas serum IgE levels were determined using sandwich IRMA assay.RESULTS: The mean level of cIgE in neonates with detectable levels was 1.59 (n = 78). No significant difference in means of cIgE was found between first born and later born neonates (p = 0.232) and between neonates of mothers with a negative and positive history of allergy (p = 0.125). Also, no significant difference was found between means of mIgE by birth order, whereas there was a significant difference of mIgE between mothers with and without a history of allergy (p = 0.01). In a group of neonates with detectable cIgE levels, maternal IgE levels were moderately correlated with cIgE levels.CONCLUSION: Cord blood IgE is not affected by birth order and mothers history of allergy, whereas mothers IgE are affected by the history of allergy but not by birth order.

Author(s):  
Abolfazl Dashti- Rahmat Abadi ◽  
Hassan Mozaffari- Khosravi ◽  
Mahdieh Nemayandeh ◽  
Mohammad Hosein Soltani ◽  
Masoud Mirzaei ◽  
...  

Background: Studies on the relationship of urinary sodium with overweight and obesity led to controversial results. Furthermore, no study has ever investigated the association between sodium status and obesity in Iranian adults. The present study examined the association of urinary sodium levels with overweight and obesity in adults living in Yazd, Iran. Methods: The present study recruited 240 adults randomly selected from adults, who participated in Yazd Health Study (YaHS). A 24-hour urine sample was collected from the participants. Participants' demographic information, history of chronic diseases, and smoking status were obtained. The height and weight of the participants were also assessed using standard methods. We compared the weight and body mass index (BMI) of the participants based on the urinary sodium excretion tertiles. The logistic regression model in crude and multivariable adjusted models was used to compare the odds of obesity between urinary sodium tertiles. Results: The findings showed that the mean urinary sodium was not significantly different among overweight, obese, and individuals with normal BMI (P > 0.05) using the crude and multivariable models. Furthermore, no significant difference was observed in the mean BMI according to urinary sodium excretion tertiles. In addition, the analyses showed that the sodium status was not significantly associated with odds of developing obesity in crude and in multivariable adjusted models. Conclusion: No significant relationship was seen between sodium status and overweight or obesity. Future prospective studies are highly recommended to confirm these results.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A248-A248
Author(s):  
Kristi Porterfield-Pruss ◽  
Denise Willis ◽  
Beverly Spray ◽  
Supriya Jambhekar

Abstract Introduction Limited evidence suggests a familial association of OSA. It is not known how often children who require positive airway pressure (PAP) devices have a family member with OSA or that requires PAP. It is felt that PAP adherence in children is affected by PAP adherence in parents. We wanted to explore the relationship of OSA in children requiring PAP to OSA in immediate family members as well as the association of obesity and adherence between children and family members. Methods Caregivers of children who utilize PAP devices at home were invited to complete an electronic questionnaire regarding family history of OSA. Descriptive statistics were utilized to summarize results. Results The study was completed by 75 participants. The majority of children were male (64%, 48/75), black (47%, 35/75) and non-Hispanic (88%, 66/75). The mean age was 11.8 years (median 13) and mean BMI was 32.8 (median 29.8). The mean AHI on the diagnostic polysomnogram was 28.4 events per hour (median 15.3). Mean adherence to PAP > 4 hours per night was 56.5 (Median 68.2). Most, 87% (65/75), have other underlying medical problems. Twenty-four percent (18/75) have a biological father with OSA of whom 61% (11/18) are considered moderately/extremely obese. Of mothers, 13% (10/75) have OSA and 70% (7/10) are obese. Overall, 29% (22/75) had either a paternal (11%, 8/75) or maternal (19%, 14/75) grandfather with OSA of which 36% (8/22) are obese. For grandmothers, 31% (23/75) have OSA and 22% (5/23) are obese with more being paternal (19%, 14/75) compared to maternal (12%, 9/75). Of the 73 total family members reported to have OSA, 86% (63/73) use PAP and most (65%, 41/63) use it for > 4 hours every night. Few participants had siblings with OSA. Conclusion There were more fathers with OSA than mothers, but mothers were reported to be obese more often. Grandparents were reported to have OSA but were reported to be obese less often than parents. Maternal grandparents with OSA were reported to be obese more than paternal grandparents. The majority of family members with OSA who use CPAP report nightly use. Support (if any):


Author(s):  
Hossein Dalili ◽  
Fatemeh Sadat Nayeri ◽  
Seyed Reza Mirjalili ◽  
Seyyed Nasrollah Hossein ◽  
Alireza Abdollahi ◽  
...  

Introduction: Intrauterine growth restriction is a multifaceted problem and is associated with a significant increase in the level of morbidity and perinatal mortality. According to some studies, failure of the placenta is responsible for the most cases of intrauterine growth restriction. The aim of this study was to evaluate the placental pathologic changes in the intrauterine growth restriction (IUGR) samples and compare them with normal cases.   Methods: A study population consisted of 60 intrauterine growth restriction neonates and 60 normalized neonates born at Tehran Imam Khomeini Hospital between June 2016 and July 2017. The placenta was weighed, immediately after delivery, and the umbilical cord was separated, then stored in 10% formalin and sent for pathological examination as soon as possible. Data collection was performed according to the following items: the pathologist's report, the results of the infants' examination, and the data in the neonatal cases.   Results: The intrauterine growth restriction group showed a high frequency of placenta infarction (P < 0.001), inflammation of the villous (P < 0.001), villous fibrosis (P = 0.044), villous vascularization disorder (P = 0.001), prevalence of chorioamnionitis (P = 0.027), prevalence of Syncytiotrophoblastic knots (P < 0.001) and placental necrosis (P = 0.048) than normal group. However, the mean weight of the placenta (P < 0.001), the length and width of the macroscopic placenta changes was less (P < 0.001).   Conclusion: The results of the current study showed that a major part of the macroscopic and histological changes are detectable in the intrauterine growth restriction samples, which are considerably more common than normal, although they are not pathognomonic, but in the future, more accurate results can be obtained from more extensive studies.


1971 ◽  
Vol 3 (1) ◽  
pp. 23-42 ◽  
Author(s):  
Michael S. Teitelbaum ◽  
Nathan Mantel

Using a large special study population and refined indicators of socio-economic status, the relationship of the live birth sex ratio to socio economic variables is examined. The analyses provide control for the possible confounding effects of race and birth order.The sex ratio is shown to be significantly and positively associated with socio-economic variables. The relationship is not linear, however, but instead is characterized by an apparent ‘diminishing returns’ curve. The major increase in sex ratio is detected as socio-economic status increases from low to moderate. No significant change occurs between moderate and higher socio-economic levels.Even after controlling for the significant socio-economic effect, the analyses detect a significant difference between the sex ratios of Whites on the one hand and Negroes and Puerto Ricans on the other.No significant association between birth order and the sex ratio can be detected in the study population.


2007 ◽  
Vol 47 (6) ◽  
pp. 278
Author(s):  
Tisnasari Hafsah ◽  
Myrna Soepriadi ◽  
Budi Setiabudiawan ◽  
Herry Garna

Background The incidence of atopic disease tends to increaseover the past few decades and its morbidity interferes with thequality of life and health. Prediction of the disease is importantfor early prevention.Objective To evaluate the relationship between atopicmanifestations, family history (FH) of atopic disease and cordblood IgE (CB-IgE) levels.Methods We conducted an analytic observational study withcohort retrospective design on children with an average age of 3years whose CB-IgE had been measured at delivery inKiaracondong Primary Health Care during October–December2004. Manifestations of atopic disease were recorded using ISAACquestionaire for allergy. Chi-square, Mann-Whitney test, andlogistic regression analysis were used for analysis.Results Cord blood IgE was measured on 124 children after birth.Only 94 children (76%) fulfilled the inclusion criteria. Atopicdisease was found in 17 children (18%), consisting of 8 childrenwith atopic dermatitis, 4 with allergic rhinitis, and 5 suffered fromboth. There were significant differences in the mean value of CB-IgE (Z M-W =4.60; P<0.001) and FH (x 2 =19.059; P<0.001)between atopic and non atopic children. Cut off point of the CB-IgE concentration was 1.4 IU/mL (77.7%). The highest probabilityfor atopic manifestations was found in children who had highCB-IgE and positive FH (P=45%). Relative risk of children withhigh CB-IgE level in positive FH group was 3.636 (95% CI0.943;14.016).Conclusion CB-IgE level and family history of atopic disease arerisk factors for the development of atopic manifestation.


1999 ◽  
Vol 85 (1) ◽  
pp. 131-137
Author(s):  
Tomoyuki Kawada

This study focused on the reliability and validity of the stress questionnaire and the relationship of responses to types of work. This self-administered questionnaire was distributed to all 799 employees of a company. 792 responded. There are 21 items with yes-no responses for which the score was the sum of assigned weights. Types of work represented manager, technical manufacturer, clerk, manufacturer, and sales. From a principal axis factor analysis three factors were extracted for men and for women, respectively. There was a significant difference in mean score among five groups of workplace positions by Kruskal-Wallis one-way analysis of covariance ( p = .04). The mean value for manager was not significant but was relatively lower than those of the other positions, suggesting that being a manager was less stressful. Confirmation with the testing of an independent sample is also needed to validate the consistency of the association.


2019 ◽  
Vol 21 (3) ◽  
pp. 144-148
Author(s):  
Masoud Nikfarjam ◽  
Elham-Sadat Salehi ◽  
Ali Ahmadi

Background and Aim: Spiritual attitude is one of the factors affecting mental health of students. The purpose of this study was to determine the relationship of religious attitudes with self-control and self-discrepancy (S-D) in students of Shahrekord University of Medical Sciences (SKUMS) in 2017. Methods: In this cross-sectional study, 328 students of the SKUMS were studied. The participants completed Tangney Self-control Survey, Higgins Self-discrepancy Questionnaire, a religious attitude questionnaire, and a checklist of demographic information. For data analysis, in addition to descriptive statistics, independent t-test, Pearson correlation coefficient, and one-way ANOVA were used. Stata software was used to analyze the data. Results: The mean values of religious attitude, self-control, and self-discrepancy were higher in women in comparison with men (P< 0.05). There was a significant difference between self-control religious beliefs, actual-self minus actual-self (S-D2), and self-discrepancy in terms of total monthly income of all family members (P< 0.05). Academic discipline was significantly associated with religious attitude, ideal-self minus actual-self (S-D1), S-D2, and S-D (P< 0.05), but self-control difference was not significant (P= 0.84). There was a linear relationship, significant correlation of religious attitude with the mean values of self-control, required self, actual-self, idea-self, self-discrepancy, and S-D1 and S-D2 (P< 0.05). Conclusion: According to the results of this study, religious attitude was associated with self-control, self-discrepancy, and their dimensions.


2020 ◽  
Vol 5 (1) ◽  
pp. e17-e17
Author(s):  
Arezoo Moradi ◽  
Fatemeh Sharif Zadeh

Introduction: Prevalence of vitamin D deficiency has been reported from all over the world since lower levels of vitamin D has been one of word’s problem in the 21st century; especially pregnant women are the most prominent one. Objectives: This study aims to investigate the relationship between mothers’ vitamin D level with infants’ birth-weight and head circumference. Patients and Methods: A cross-sectional study was conducted in the department of obstetrics and gynecology of Akbarabadi hospital during 2017-2018. Regarding two groups, infants’ three main characteristics including their weight, head circumference and height were studied. Results: The mean blood levels of vitamin D in mothers with normal-born neonates were 15.23 ± 7.14 (ng/ mL) and in the mothers who gave birth to low-birth weight were 10.02 ± 8.06 (ng/mL), which was significantly lower than the mothers of normal-weight infants (P=0.018). The mean blood levels of vitamin D in mothers who gave birth to a normal head circumference neonate were 16.07 ± 8.1 (ng/mL) and in mothers with infants’ head circumference of less than 33 cm, was 9.87 ± 7.57 (ng/mL), which was significantly lower from mothers of normal-head circumference infants (P=0.007). The serum levels of vitamin D in mothers with normal-height infants were 14.74 ± 7.52 (ng/mL) and in the mothers with a height of less than 47 cm were 15.17 ± 7.91 (ng/mL), that does not suggest any significant difference (P=0.341). The mean serum vitamin D level in mothers who had normal vaginal delivery was lower than those with cesarean delivery, however there was no significant difference (P=0.174). Conclusion: Nutrition improvement and prescribing vitamin D supplements can positively be effective in the way of curbing low-birth weight infants. Moreover, Exposure to sunlight and letting rays strike skin is essential for maintaining a healthy vitamin D status for girls and women.


1956 ◽  
Vol 7 (1) ◽  
pp. 57 ◽  
Author(s):  
PG Schinckel

The relationship of body weight to wool production was examined in a flock of Merino sheep of South Australian strain over a period of 7 years. In only one out of 10 groups examined was there a significant correlation between body weight and the amount of clean wool produced per unit area of midside skin. It is concluded that body weight and wool production per unit area of body surface are independent. In all groups there was a highly significant correlation between clean fleece weight and clean wool per unit area of body surface in the midside region. The regression of log fleece weight on log body weight was determined in 15 groups. In no case was the regression coefficient significantly different from 0.60. As the regression of log surface area on log body weight in sheep is of the order of 0.60, it is concluded that wool production is proportional to fleece-bearing surface. The mean regression coefficients of log fleece weight on log body weight, calculated within sire and year groups, were: rams, 0.52 ± 0.056; ewes, 0.61 ± 0.038; wethers, 0.30 ± 0.068. There were no significant differences between sires in the regression of log fleece weight on log body weight. There were, however, highly significant differences between sire groups in mean log fleece weight, after adjustment for differences in log body weight. Skin areas 3 by 3 cm were tattooed on the left midside of 24 lambs at 1 month of age. The wool produced on these areas, and the areas of the tattoos, were measured at 4-monthly intervals from 4 months of age until 28 months. The amount of wool produced m7as proportional to the area in each of the six periods. There was also a highly significant difference between periods and between sheep in the amount of wool produced after adjustment for differences in tattoo area.


Author(s):  
Seda Yörük

Objectives: The aim of the study was to determine the relationship between emotions, thoughts with anger and aggression. Methods: The cross-sectional study was conducted at the Vocational School of a university. A total of 238 students participated in this study. The data collection tools of the study are sociodemographic data form, Buss-Perry aggression scale, trait anger and anger expression style scales. The study of descriptive statistical results of data were calculated with arithmetic mean, standard deviation, number, percentage. In determining the factors affecting the average of aggression and anger score were calculated independent sample t test, Mann-Whitney U test, one-way analysis of variance and Kruskal Wallis variance analysis. In the analysis, the obtained p value less than 0.05 was accepted as significant difference. Results: The smoking, family income, family verbal violence and family history of violence were found to be significant in predicting the anger score. The mean scores of anger subscale scores were significantly higher in the students who had high risk taking behaviors, who did not understand her and who did not agree and disagreed, thought that who thinks life is meaningless and looking hopeless for the future that students (p <0.016). The mean score of physical aggression was significantly higher in male students (p <0.0001). The scores of aggression subscale scores were significantly higher in the students who were smoking, had verbal violence between their parents, had a childhood history of violence, their parents had been violent in childhood, had a history of aggressive behavior, and who reported depressive mood in the last year (p < 0.05). Conclusion: In this study, ıt was found that anger and aggression were found to be high and risky behaviors along with family and friend relationships were an important in young people.


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