The association of serum magnesium with serum triglyceride and cholesterol levels in hemodialysis patients

Introduction: Dysregulated lipid profile has been described in patients with chronic renal failure. Objectives: In the present study, we investigated the association of serum magnesium level with serum triglyceride and cholesterol levels in a group of hemodialysis individuals. Patients and Methods: This cross-sectional study was carried out on hemodialysis patients referred to the Hajar hospital of Shahrekord (2015). Patients who have been on hemodialysis for at least three months and had a stable condition for the last two months were recruited. Serum levels of magnesium, cholesterol, and triglyceride were measured, and the data was analyzed. Results: Of 52 patients, 61.5% were males. The mean age of the patients was 60.17 ± 48.70 (range; 13-78) years and the mean dialysis duration was 44.39 ± 05.52 months. Serum magnesium was inversely and insignificantly correlated with serum cholesterol and triglyceride levels. Serum magnesium was significantly associated with serum albumin and parathormone. Conclusion: We found non-significant and inverse correlations of serum magnesium with serum cholesterol and triglyceride levels. The association between serum magnesium and dyslipidemia is contradictory, and further studies are required to divulge the role of other contributing factors.

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Evaluation of Serum Triglyceride and Total Cholesterol Status in Adolescent Smoker

Journal of Bangladesh Society of Physiologist ◽

10.3329/jbsp.v1i0.715 ◽

1970 ◽

Vol 1 ◽

pp. 14-18

Author(s):

L Afrin ◽

R Sultana ◽

S Ferdousi ◽

A Ahmed ◽

MR Amin

Keyword(s):

Total Cholesterol ◽

Serum Lipid ◽

Serum Triglyceride ◽

Adolescent Male ◽

Serum Triglyceride Level ◽

Cross Sectional ◽

Cholesterol Levels ◽

Increased Risk ◽

The Mean ◽

Dose Response Effect

Objectives: A cross sectional comparative study was performed to evaluate the changes of the serum lipid profile in apparently healthy adolescent male non smokers and smokers subjects. Method: This study was carried out in the department of Physiology of Dhaka Medical College from January to December 2005. For this purpose, total 80 subjects with age range 12-19 years were selected, of whom 20 were non smokers (control) and 60 were smokers (experimental) who smoked for at least one year. Again smokers were grouped according to the number of cigarettes smoked per week, ( mild < 19, moderate 20-59, heavy >60). Fasting serum Triglyceride and total Cholesterol levels of all subjects were measured. Data were compared between smokers and non smokers and between non smoker and mild moderate and heavy smokers and analyzed statistically by unpaired t test. Result: Mean ±SD Triglyceride levels were136.80mg/dl ± 42.18 vs. 153.12mg/dl ± 26.66 and Mean ±SD Total Cholesterol levels were 165.20mg/dl ± 15.13 vs165.36mg/dl ± 10.12 in non smokers and smokers respectively. there were no significant changes in the mean serum total cholesterol levels in adolescent smokers but the mean serum triglyceride level in smokers were significantly higher (p<0.01 )than that of non smokers. hyper Triglyceridemia (TG level> 150mg/dl) were observed in 56% of smoker subjects whereas 36% in non smokers. The dose response effect of smoking was observed in serum triglyceride levels of smoker subgroups. Mean ±SD TG levels in mild, moderate, heavy groups were 148.15mg/dl± 21.32,152.8mg/dl± 29.49,154.12mg/dl± 23.75 respectively. Conclusion: From the result of the present study it may be concluded that, cigarette smoking during adolescent period induces alteration in serum lipid levels in the direction of increased risk for coronary artery disease. J Bangladesh Soc Physiol. 2006 Dec;(1):14-18

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The effect of coffee consumption on serum total cholesterol in the Sami and Norwegian populations

Public Health Nutrition ◽

10.1017/s1368980010000376 ◽

2010 ◽

Vol 13 (11) ◽

pp. 1818-1825 ◽

Cited By ~ 7

Author(s):

Tove Nystad ◽

Marita Melhus ◽

Magritt Brustad ◽

Eiliv Lund

Keyword(s):

Total Cholesterol ◽

Serum Cholesterol ◽

Coffee Consumption ◽

Cross Sectional Study ◽

Total Serum ◽

Total Serum Cholesterol ◽

Cross Sectional ◽

Cholesterol Levels ◽

The Mean ◽

The Impact

AbstractObjectiveTo assess coffee consumption in the Sami and Norwegian populations and to investigate the impact of unfiltered boiled coffee consumption on serum cholesterol concentrations.DesignA cross-sectional study. Information was collected by self-administrated questionnaires and total serum cholesterol was analysed. Participants were divided into three ethnic groups: Sami I (Sami used as home language in the last three generations), Sami II (at least one Sami identity marker) and Norwegian.SettingIn an area with Sami, Kven/Finnish and Norwegian populations, the SAMINOR study, 2003–2004.SubjectsA total of 5647 men and 6347 women aged 36–79 years.ResultsMore than 90 % of the study populations were coffee drinkers. Only 22 % were unfiltered coffee consumers. Sami I had the highest proportion of participants who consumed nine or more cups of unfiltered coffee per day, although the number of participants was limited. Total coffee consumption was associated with increased total cholesterol for men (P < 0·01) and women (P < 0·0001). For those who drank only unfiltered coffee, a significant association was found only in Norwegian men, adjusted for physical activity in leisure time, BMI and smoking habits (P < 0·001). From the lowest (less than five cups) to the highest (nine or more cups) unfiltered coffee consumption category, the mean total cholesterol levels increased by 0·29 mmol/l in Norwegian men.ConclusionsUnfiltered coffee consumption was lower in the present study compared to previous reports. In general, total coffee consumption was positively associated with total cholesterol levels. However, for unfiltered coffee consumption, an association was found only in Norwegian men.

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Hypomagnesemia in hemodialysis patients taking proton pump inhibitors

Journal of Fatima Jinnah Medical University ◽

10.37018/dezk2659 ◽

2020 ◽

Vol 14 (2) ◽

pp. 55-58

Author(s):

Abdul Malik ◽

Syed Mohkumuddin ◽

Humaira Rahim ◽

Shamima Hanif

Keyword(s):

Proton Pump Inhibitors ◽

Proton Pump ◽

Serum Magnesium ◽

Cross Sectional Study ◽

Hemodialysis Patients ◽

Mean Value ◽

Female Dominance ◽

P Value ◽

Cross Sectional ◽

The Mean

Background: Proton pump inhibitors (PPIs) are in routine widely prescribed to hemodialysis patients. Recent studies have reported the association of PPIs use with hypomagnesemia in patients with long term hemodialysis. This study aims to determine the frequency of hypomagnesemia in patients of hemodialysis taking proton pump inhibitors. Patients and methods: This cross-sectional study was conducted in the Department of Nephrology of Sandman Provincial Hospital Quetta from 01-6-2019 till 01-9-2019. A total of 120 patients (52 PPI users and 68 non-PPI users) who were on HD for more than 06 months were included. Data regarding age, gender, duration of hemodialysis and taking PPIs were collected. Determination of serum magnesium was made by taking 3 different samples at 2 weeks’ interval and the mean value of serum magnesium was calculated. Serum Mg2+ levels <2.0 mg/dL was taken as hypomagnesemia. A Chi-square test was applied to determine the association of PPI use with hypomagnesemia. Results: Demographic variables such as age and gender were not significantly different between the groups. There was female dominance in both groups (73% in PPI groups and 66.1% in the non-PPI group (p-value 0.65). The mean duration of dialysis was 45.3±13.8 months in PPI users versus 48.9±12.9 months in non-PPI users (p-value 0.14). There was a significantly higher frequency of hypomagnesemia in PPI users; 36 (69.3%) versus 27 (39.7%) in non-PPI users (p-value 0.001). Conclusion: The use of PPI is associated with a significant reduction in serum magnesium levels. So serum magnesium levels should be advised as routine monitoring in patients of hemodialysis taking PPIs.

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Metabolic Effects of Two Different Doses of Venlafaxine Therapy on Rats

Acta Medica Marisiensis ◽

10.1515/amma-2015-0049 ◽

2015 ◽

Vol 61 (3) ◽

pp. 196-199

Author(s):

Imre Annamária ◽

Kolcsár Melinda ◽

Groşan Alexandra ◽

M Imre ◽

Dogaru Maria Titica

Keyword(s):

Serum Cholesterol ◽

Serum Triglyceride ◽

Metabolic Effects ◽

Control Group ◽

Glucose Levels ◽

Cholesterol Levels ◽

Norepinephrine Reuptake Inhibitor ◽

The Mean ◽

Access To Food ◽

Different Doses

AbstractObjectives: Venlafaxine is an antidepressant, categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI) with suspected metabolic side effects. The aim of our study was to assess these metabolic effects in rats, using two different doses of venlafaxine.Materials: Three groups of Wistar rats have been treated with venlafaxine during seven weeks. The rats have received a daily dose of 10mg/kg (D1) and 40 mg/kg (D2) while the control group (Dc) has received no treatment. Rats were given “ad libitum” access to food and water. The rats were weighted at treatment day 0, 7, 14, 21, 28, 35, 42 and 49. After completion of venlafaxine treatment, the rats were sacrificed, blood was harvested and the following biochemical parameters have been determined from the centrifuged plasma: triglycerides, glucose and total cholesterol levels.Results: Both the 10 mg/kg and the 40 mg/kg dose venlafaxine therapy resulted in a highly significant increase of rat’s weight. Compared with the control group the mean weight of D1 group has increased with 130.5 ±21.79 g (<0.01) while the mean weight of the second group increased with 94±24.16 g (p<0.01). In addition weight gain of D1 group was significantly higher than that of D2 group (p<0.01). Venlafaxine therapy induced significant increase in serum triglyceride levels (140.04±55.46 mg/dL p<0.01, 83.59±52.85 mg/dL p=0.05). This metabolic effect has been shown to be more evident in case of 10mg/kg dose therapy (p=0.03). Simultaneously, serum cholesterol levels have been reduced, however this decrease proved to be significant only in case of group D2 (p=0.03). Despite of increased triglyceride values, glucose levels were significantly decreased in both treated groups (133.33±36.18mg/dL p=0.05, 118.10±51.98 mg/dL p=0.02).Conclusions: Our results suggest that venlafaxine administrated to rats has unwished dose related metabolic effects such as significant increase in weight and hypertriglyceridemia, however serum cholesterol and plasma glucose levels appears to be decreased by this medication.

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Study of Serum Magnesium levels in diabetic patients with and without retinopathy.

The Professional Medical Journal ◽

10.29309/tpmj/2020.27.12.4132 ◽

2020 ◽

Vol 27 (12) ◽

pp. 2656-2661

Author(s):

Sadiq Hussain ◽

Sara Reza ◽

Hashim Raza ◽

Saleha Zafar ◽

Sami Ahmad ◽

...

Keyword(s):

Diabetic Retinopathy ◽

Serum Magnesium ◽

Serum Levels ◽

Control Group ◽

Diabetic Patients ◽

Considerable Decrease ◽

Lower Serum ◽

Cross Sectional ◽

The Mean ◽

Healthy Participants

Objectives: The aim of our study is to evaluate the possible association of serum magnesium in diabetic patients with and without retinopathy. Study Design: Cross-sectional observational. Setting: Bahawal Victoria Hospital, Bahawalpur. Period: September, 2018 to May, 2019. Material & Methods: A total of 258 subjects were enrolled in the study. They were divided in 3 groups, which comprised of 208 diabetic patients; 92 with retinopathy, 116 without retinopathy and the control group comprised of 50 healthy individuals. Both cases and controls were subjected to blood tests for the estimation of biochemical parameters. Results: A considerable decrease was observed in the serum magnesium level of diabetics in comparison with the healthy participants. The mean serum magnesium levels amongst the groups were 1.5 ± 0.2 mg/dl and 2.4 ± 0.3 mg/dl respectively (p<0.001). There was also a marked variation in serum levels of magnesium among diabetic retinopathy patients and diabetics without complications i.e.1.3±0.1 mg/dl and 1.69±0.1 mg/dl respectively (p<0.001). Conclusion: Patients suffering from diabetic retinopathy displayed significantly lower serum magnesium levels in contrast to the control group and diabetics without retinopathy.

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Depression and Cognitive Impairment in Patients on Hemodialysis: A cross-sectional study

Environment-Behaviour Proceedings Journal ◽

10.21834/ebpj.v5i15.2468 ◽

2020 ◽

Vol 5 (15) ◽

pp. 185-192

Author(s):

Nor Jannah Nasution Raduan ◽

Mohd Razali Salleh ◽

Ghazali Ahmad ◽

Zaleha Ismail

Keyword(s):

Cognitive Impairment ◽

Publishing House ◽

Cross Sectional Study ◽

Hemodialysis Patients ◽

Education Level ◽

Sectional Study ◽

Contributing Factors ◽

Cross Sectional ◽

Factors Associated ◽

Low Education

Depression and cognitive impairment are the most common complications of patients on hemodialysis. The objective of this study is to identify contributing factors to depression and cognitive impairment in hemodialysis patients. This is a cross-sectional study involving 110 hemodialysis patients in Hospital Kuala Lumpur. The samples were recruited through universal sampling. Patients were assessed with the Beck Depression Inventory and Montreal Cognitive Assessment. This study found that 18.2% of patients had depression, and 48.2% had cognitive impairment. Factors associated with depression were unmarried status, low education level, and cognitive impairment. Factors associated with cognitive impairment were low education level, depression, and unemployment. Keywords: hemodialysis, depression, cognitive, ESRD eISSN: 2398-4287© 2020. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open access article under the CC BYNC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia. DOI: https://doi.org/10.21834/ebpj.v5i15.2468.

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An Assessment of Serum Cholesterol level and BMI in Women: Study in Several Private Chambers in Mymensingh

Community Based Medical Journal ◽

10.3329/cbmj.v8i2.55766 ◽

2019 ◽

Vol 8 (2) ◽

pp. 4-9

Author(s):

Nahid Bintay Ansary ◽

Arup Ratan Paul ◽

Md Mahamudur Rahman ◽

Maria Hussain ◽

Rubiat Naznin

Keyword(s):

Cardiovascular Disease ◽

Health Status ◽

Cholesterol Level ◽

Serum Cholesterol ◽

Serum Cholesterol Level ◽

Normal Weight ◽

Cholesterol Levels ◽

Increased Risk ◽

The Mean ◽

Study Participants

The increased risk of cardiovascular disease associated with higher serum cholesterol levels in middle-aged persons has been established, but there have been few studies conducted regarding the issues in Mymensingh. For evaluation of serum cholesterol and BMI in women of Mymensingh, across-sectional studywas conducted in several private chambers in the districts of Mymensingh, Bangladesh during the period from January 2017 to December 2017. A total of 48 Female patients participated in the study. In the study, participants were aged between 18 to 29 years of age. The study suggested that the serum cholesterol was below 4.99 were 15(31.25%), 5.00 to 6.49 were 13(26.08%) and above 6.50 were 20 (41.67%), the Mean ± SD was 4.45 (0.76). The health status according to BMI showed that 12.50% (n=6) of the participants were underweight <18.49, majority 50.00% (n=24) of the population were from normal weight range (18.5-24.9), 16.67% (n=8) of the participants were overweight and 20.83 %( n=10) of the participants were obese >30. The Mean ± SD was 18.93± (3.68). Measurement of BMI and Serum Cholesterol levels can help doctors to treat patients properly for reducing the burden of death in our country. CBMJ 2019 July: Vol. 08 No. 02 P: 4-9

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A Study on Some Serum Biological Constituents during Different Days of Normal Oestrous Cycle of Manipuri Pony Mares

Indian Journal of Animal Research ◽

10.18805/ijar.b-4476 ◽

2021 ◽

Author(s):

Ningthoukhongjam Linda ◽

Fazal Ali Ahmed ◽

J.K. Chaudhary ◽

Mohammad Ayub Ali ◽

Jagan Mohanarao Gali

Keyword(s):

Total Protein ◽

Serum Magnesium ◽

Serum Levels ◽

Oestrous Cycle ◽

Serum Magnesium Level ◽

Calcium Phosphorus ◽

Serum Biochemical ◽

The Mean ◽

Hormonal Assay ◽

Apparently Healthy

Background: The aim of this study was to estimate the serum biochemical (glucose, cholesterol, total protein, calcium, phosphorus and magnesium) and hormonal constituents (estrogen and progesterone) in female Manipuri pony mares during the different days of oestrous cycle. Methods: A total of 50 numbers of blood samples were collected from 10 numbers of apparently healthy, non-pregnant on the different days of oestrous cycle i.e. day 0, 4, 8, 14 and 18 by using commercial diagnostic kits. Result: The mean serum levels of glucose, cholesterol and phosphorus were found to be non-significant on the different days of oestrous cycle whereas the mean serum level of total protein and calcium was found significantly different (P less than 0.01). The serum magnesium level differed significantly (P less than 0.05) amongst the different days of oestrous cycle. Both estrogen and progesterone were also found to be significant (P less than 0.01) between the different days of oestrous cycle. The results showed significant influence on serum biochemical and hormonal assay during different days of oestrous cycle in female Manipuri pony.

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Relationship between Serum Cholesterol Levels and Television Viewing in 11,947 Employed Adults

American Journal of Health Promotion ◽

10.4278/0890-1171-6.6.437 ◽

1992 ◽

Vol 6 (6) ◽

pp. 437-442 ◽

Cited By ~ 6

Author(s):

Larry A. Tucker ◽

Marilyn Bagwell

Keyword(s):

Body Fat ◽

Serum Cholesterol ◽

Television Viewing ◽

Exercise Duration ◽

Management Program ◽

Lifestyle Factor ◽

Fat Percentage ◽

Cross Sectional ◽

Cholesterol Levels ◽

Three Body

Purpose. The purpose of this study was to determine the prevalence of hypercholesterolemia among high-, moderate-, and low-duration television viewers. The confounding effects of age, gender, income, body fat percentage, weekly exercise duration, and smoking were also examined. Design. A cross-sectional or correlational design was employed. Cochran-Mantel-Haenszel odds ratios were used to estimate risk of the television viewers regarding hypercholesterolemia. Setting. Participants were employees of over 55 corporations that had their employees screened as part of the ongoing risk-management program of Health Advancement Services (HAS), Inc. Subjects. Subjects were 11,947 employed adults. About 85% of the subjects eligible for participation completed the screenings and were used in the study. Measures. Serum cholesterol was assessed in a certified lab, and lifestyle information, including television viewing habits, was collected via a written questionnaire. Body fat was measured using skinfolds from three body sites. Results. High-duration television viewers were almost two times more likely to suffer from hypercholesterolemia as infrequent viewers, with and without control of multiple confounding factors. Moderate-duration viewers were at 1.5 times the risk of hypercholesterolemia compared to infrequent viewers. Neither television group was at greater risk of moderately elevated cholesterol levels (200–239) compared to the infrequent viewers with all of the potential confounders controlled. Conclusions. Cause-and-effect conclusions are not warranted; however, this study coupled with other investigations shows that excessive television viewing may be an important lifestyle factor linked to decreased health and functioning.

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