scholarly journals Evaluation of Serum Triglyceride and Total Cholesterol Status in Adolescent Smoker

1970 ◽  
Vol 1 ◽  
pp. 14-18
Author(s):  
L Afrin ◽  
R Sultana ◽  
S Ferdousi ◽  
A Ahmed ◽  
MR Amin

Objectives: A cross sectional comparative study was performed to evaluate the changes of the serum lipid profile in apparently healthy adolescent male non smokers and smokers’ subjects. Method: This study was carried out in the department of Physiology of Dhaka Medical College from January to December 2005. For this purpose, total 80 subjects with age range 12-19 years were selected, of whom 20 were non smokers (control) and 60 were smokers (experimental) who smoked for at least one year. Again smokers were grouped according to the number of cigarettes smoked per week, ( mild < 19, moderate 20-59, heavy >60). Fasting serum Triglyceride and total Cholesterol levels of all subjects were measured. Data were compared between smokers and non smokers and between non smoker and mild moderate and heavy smokers and analyzed statistically by unpaired t test. Result: Mean ±SD Triglyceride levels were136.80mg/dl ± 42.18 vs. 153.12mg/dl ± 26.66 and Mean ±SD Total Cholesterol levels were 165.20mg/dl ± 15.13 vs165.36mg/dl ± 10.12 in non smokers and smokers respectively. there were no significant changes in the mean serum total cholesterol levels in adolescent smokers but the mean serum triglyceride level in smokers were significantly higher (p<0.01 )than that of non smokers. hyper Triglyceridemia (TG level> 150mg/dl) were observed in 56% of smoker subjects whereas 36% in non smokers. The dose response effect of smoking was observed in serum triglyceride levels of smoker subgroups. Mean ±SD TG levels in mild, moderate, heavy groups were 148.15mg/dl± 21.32,152.8mg/dl± 29.49,154.12mg/dl± 23.75 respectively. Conclusion: From the result of the present study it may be concluded that, cigarette smoking during adolescent period induces alteration in serum lipid levels in the direction of increased risk for coronary artery disease. J Bangladesh Soc Physiol. 2006 Dec;(1):14-18

Author(s):  
Chandrashekar V. Kubihal ◽  
Hemalatha D. Naik

Background: Several studies have reported elevated blood cholesterol levels among persons who regularly smoke cigarettes and lowered blood cholesterol levels among persons quitting smoking. Other studies have also shown that smoking lowers high density lipoprotein level, resulting in an increased risk of coronary heart disease. Smoking also leads to increase in LDL cholesterol and triglyceride levels. The objective was to study serum lipid profile in smokers and non-smokers.Methods: A cross sectional comparative study was carried in 100 subjects. The subjects were divided into two groups. First group consisted of 25 nonsmokers and second group of 75 smokers. The group of 75 smokers was again divided into three equal sub groups of 25 each depending upon the duration and intensity of smoking. Concentration of serum total cholesterol and HDL was determined by Zak’s method. Concentration of serum LDL and VLDL cholesterol was determined by Friedwald’s formula. Concentration of serum triglyceride level was determined by enzymatic end point peroxidase coupled method.Results: All the values of lipid profile i.e., total cholesterol, triglycerides, LDL, VLDL were found to be significantly higher among the smokers compared to the non-smokers. HDL value was significantly lower among smokers. As the degree of smoking increased from mild to heavy smokers, the values of total cholesterol, triglycerides, LDL and VLDL increased. The degree of smoking was inversely proportional to HDL values i.e., the HDL value decreased as the smoking degree increased.Conclusions: Thus, it can be said based on the present study that smoking affects and deranges the lipid profile of the person.


2010 ◽  
Vol 13 (11) ◽  
pp. 1818-1825 ◽  
Author(s):  
Tove Nystad ◽  
Marita Melhus ◽  
Magritt Brustad ◽  
Eiliv Lund

AbstractObjectiveTo assess coffee consumption in the Sami and Norwegian populations and to investigate the impact of unfiltered boiled coffee consumption on serum cholesterol concentrations.DesignA cross-sectional study. Information was collected by self-administrated questionnaires and total serum cholesterol was analysed. Participants were divided into three ethnic groups: Sami I (Sami used as home language in the last three generations), Sami II (at least one Sami identity marker) and Norwegian.SettingIn an area with Sami, Kven/Finnish and Norwegian populations, the SAMINOR study, 2003–2004.SubjectsA total of 5647 men and 6347 women aged 36–79 years.ResultsMore than 90 % of the study populations were coffee drinkers. Only 22 % were unfiltered coffee consumers. Sami I had the highest proportion of participants who consumed nine or more cups of unfiltered coffee per day, although the number of participants was limited. Total coffee consumption was associated with increased total cholesterol for men (P < 0·01) and women (P < 0·0001). For those who drank only unfiltered coffee, a significant association was found only in Norwegian men, adjusted for physical activity in leisure time, BMI and smoking habits (P < 0·001). From the lowest (less than five cups) to the highest (nine or more cups) unfiltered coffee consumption category, the mean total cholesterol levels increased by 0·29 mmol/l in Norwegian men.ConclusionsUnfiltered coffee consumption was lower in the present study compared to previous reports. In general, total coffee consumption was positively associated with total cholesterol levels. However, for unfiltered coffee consumption, an association was found only in Norwegian men.


2011 ◽  
Vol 5 (2) ◽  
pp. 71-74
Author(s):  
Dilruba Akther ◽  
Ruhul Amin ◽  
US Naima Begum ◽  
Najneen Akhter ◽  
Nasrin Habib ◽  
...  

Background: Exercise plays a role in preventing cardiovascular disease as well as other serious health problems. Objectives: A cross sectional comparative study was performed to observe the changes in serum total cholesterol and triglyceride in apparently healthy female athletes. Methods: This study was carried out in the Department of Physiology of Dhaka Medical College from July 2005 to June 2006. For this, 30 female athletes aged 17 to 38 years (experimental) who were under regular physical exercise training for at least two years and age matched 30 healthy female non athletes (control) for comparison were selected. Fasting serum Triglyceride and total Cholesterol levels of all the subjects were measured. Data were compared between athletes and non athletes and analyzed statistically by unpaired 't' test. Results: Mean±SD cholesterol levels were 141.10 ±14.46 & 165.10±7.03 and Mean±SD Triglyceride levels were 76.10±11.54 & 96.60±17.02 in athletes and non athletes respectively. Serum total cholesterol (p<0.001) and triglycerides (p<0.01) were significantly lower; in athletes compared to those of non athlets. Conclusion: From this study it can be concluded that, serum total cholesterol and triglycerides may be lowered in athletes. Key words: Female athletes; Cholesterol; Triglyceride. DOI: 10.3329/jbsp.v5i2.6780J Bangladesh Soc Physiol. 2010 December; 5(2): 71-74


Jurnal NERS ◽  
2017 ◽  
Vol 12 (1) ◽  
pp. 88
Author(s):  
Musfirah Ahmad ◽  
Rini Rachmawaty ◽  
Elly L. Sjattar ◽  
Saldy Yusuf

Introduction: Diabetes mellitus (DM) is a global disease endemic and causing of 4.6 million deaths in the world. The Indonesian government and health insurance [BPJS Kesehatan] formulate a Chronic Disease Care Program [Program Pengelolaan Penyakit Kronis (PROLANIS)] for type 2 diabetes that aimed at controlling the glycemic status and the risk factors of macro and microvascular complications. The purpose of this study was to analyze the correlation between the implementation of PROLANIS and fasting blood sugar, HbA1c, and total cholesterol levels in patients diagnosed with type 2 diabetes at Antang and Pampang community health centers, Makassar, Indonesia. Methods: This study used descriptive correlation design with cross sectional study approach. Subjects were 40 patients diagnosed with type 2 diabetes who joined PROLANIS at PUSKESMAS Antang and Pampang, Makassar, with sampling technique used was total sampling. The data were analyzed using correlation test to assess the significance (p), the direction (+/-), and the strength of the correlation (r). The implementation of PROLANIS was measured by using the observation sheets developed based on BPJS Kesehatan criteria, while the fasting blood sugar, HbA1c, and total cholesterol levels were checked by laboratory. Results: The mean of the implementation of PROLANIS was 15.05 (SD ± 5.62), while the mean levels of fasting blood sugar, HbA1c, and total cholesterolwere as followed: 191.80 mg/dL (SD ± 85.15); 8.4% (SD ± 2.08); and 192.87 mg/dL (SD ± 45.07). Using the Spearman's rho test, the study result showed that there was a significant and negative correlation between the implementation of PROLANIS and the levels of fasting blood sugar (p= 0.001; r= -0.724), HbA1c (p= 0.001; r= -0.870), and total cholesterol (p= 0.029; r= -0.35) in patients diagnosed with type 2 diabetes at Puskemas Antang and Pampang, Makassar. Conclusions: The optimal implementation of the PROLANIS is very effective to control the levels of fasting blood sugar, HbA1c, and total cholesterol in patients type 2 diabetes. 


2013 ◽  
Vol 1 (2) ◽  
Author(s):  
Hanif B. S. Gani

Abstract: In general, obesity is associated with a decrease of blood HDL-cholesterol level and an increase of serum triglyceride level. In obese people, the  triglyceride is deposited in the subcutaneous layer of the skin. This triglyceride plays an important role in the formation of VLDL and LDL-cholesterol in the liver which will be released into the blood. This was an observational study with a cross-sectional design. Samples were 22 obese female students and 22 non-obese female students of Faculty of Medicine, University of Sam Ratulangi Manado aged 18-22 years. The results showed that the mean HDL-cholesterol levels in obese females was 57.64 mg/dL, meanwhile of the non-obese females was 61.77 mg/dL. Albeit, the statistical analysis showed no significant difference between the HDL-cholesterol levels of obese and non-obese females (P-value 0.974). Conclusion: There was no significant difference between the HDL-cholesterol levels of obese females and non obese females. Keywords: HDL-cholesterol levels, females, obese, non obese     Abstrak: Obesitas berhubungan dengan penurunan kadar kolesterol HDL darah dan peningkatan kadar serum trigliserida.3 Pada individu obes, trigliserida disimpan pada jaringan subkutan. Trigliserida itu merupakan bahan utama pembentukan VLDL dan LDL di hati yang akan dilepaskan ke dalam darah. Penelitian ini bersifat observasional dengan menggunakan cross-sectional design. Sampel penelitian terdiri dari 22 mahasiswi Fakultas Kedokteran Universitas Sam Ratulangi yang obes dan 22 mahasiswi yang non-obes. Hasil penelitian memperlihatkan bahwa rerata kadar kolesterol HDL pada sampel yang obes 57,64 mg/dL dan pada yang non-obes 61,77 mg/dL. Uji statistik memperlihatkan tidak terdapat perbedaan bermakna antara kadar kolesterol HDL darah pada wanita yang obes dan yang non-obes (P = 0,974). Simpulan: Tidak terdapat perbedaan bermakna antara kadar kolesterol HDL darah pada wanita obes dan wanita non-obes. Kata kunci: kadar kolestrol HDL, wanita, obes, non-obes.


2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Oktavia T. Waani ◽  
Murniati Tiho ◽  
Stefana H.M. Kaligis

Abstract: Cholesterol is a major component of brain and nerve cells and also as the resources for a number of important compunds in the body. The intensity of a person’s activity affect the levels of cholesterol in the body. Physical inactivity is one of the risk factors for lipid accumulation in the body which can cause a strain in the heart and blood vessels. This study aimed to determine the total cholesterol levels in office workers. The design of this study was a descriptive analysis with a cross sectional study. Samples were 52 people taken with total sampling method. The result showed the respondents with normal cholesterol levels were the same number as respondents with high cholesterol levels (50,00%; 26 people). The mean cholesterol levels of 52 samples was 198 mg/dL, the median was 201 mg/dL, the modus was 214 mg/dL, the minimal dan maximal were 143 mg/dL and 273 mg/dL, and the strandard deviation was 29,22. Conclusion: The number of respondents with normal cholesterol levels and with high cholesterol levels are equal.Keywords: the total cholesterol levels, office workers Abstrak: Kolesterol merupakan komponen utama sel otak dan saraf, serta merupakan bahan pembentuk sejumlah senyawa penting dalam tubuh. Intensitas akivitas seseorang berpengaruh terhadap kadar kolesterol dalam tubuh. Kurangnya aktivitas fisik merupakan salah satu faktor risiko penumpukan lipid dalam tubuh sehingga yang dapat menyebabkan gangguan pada jantung dan pembuluh darah. Tujuan dari penelitian ini adalah untuk mengetahui gambaran kadar kolesterol total darah pada pekerja kantor. Penelitian yang digunakan bersifat deskriptif dengan pendekatan cross sectional. Sampel dalam penelitian ini berjumlah 52 orang yang sesuai kriteria inklusi dan bersedia menjadi responden. Metode pemilihan sampel menggunakan cara total sampling. Hasil penelitian responden dengan kadar kolesterol normal (<200 mg/dL) dan responden dengan kadar kolesterol tinggi memiliki jumlah responden yang seimbang yaitu sebanyak 26 orang (50,00%). Nilai rata-rata yaitu 198 mg/dL, nilai median 201 mg/dL, nilai modus 214 mg/dL, nilai minimal 143 mg/dL, nilai maksimal 273 mg/dL, dan standar deviasi 29,22. Simpulan: Jumlah antara responden dengan kadar kolesterol darah normal dengan kadar kolesterol darah tinggi adalah seimbang. Kata kunci: kadar kolesterol total darah, pekerja kantor.


Author(s):  
Martiem Mawi ◽  
Fransisca Chondro ◽  
Juni Chudri

Background<br />Atherosclerosis, the underlying cause of heart attack, stroke and peripheral disease, is a main cause of morbidity and mortality worldwide. Hypercholesterolemia and hypertriglyceridemia are independent factors in the development and progression of atherosclerosis. The atherosclerotic index (AI) is a strong indicator of cardiovascular heart disease. The objective of this study was to determine the relationship between lipid serum level and AI in subjects 50-70 years of age. <br /><br />Methods <br />A study of cross-sectional design was conducted among male and female subjects 50-70 years of age. The inclusion criteria were: healthy, and capable of active communication. The exclusion criteria were: subjects not completing the study, currently consuming antihyperlipidemic drugs. Lipid profile comprising total cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), triglycerides, and malondialdehyde (MDA), was analyzed using commercial kits. Systolic and diastolic blood pressure and body mass index was measured in all subjects. Atherogenic index was calculated from (total cholesterol – HDL cholesterol) / HDL cholesterol. Multiple linear regression was used to analyze the data.<br /><br />Results <br />Mean age of the subjects was 60.6 ± 3.30 years and there was a significant relationship of LDL cholesterol and triglycerides with AI (b=0.009; p=0.000 and b=0.008; p=0.000, respectively). Triglyceride level was the most influencing factor for AI (b=0.008; Beta=0.616; p=0.000)<br /><br />Conclusions<br />Higher triglyceride levels increase AI in subjects 50-70 years of age. Subjects with high serum triglyceride level but without symptoms of cardiovascular disease should be examined for the development of coronary artery blockage.


Author(s):  
Shruti Chandra ◽  
S. P. Singh ◽  
Rashmi Singh ◽  
Neeraj Kumar Agarwal

Background: Hypertension with dislipidemia is becoming a common morbidity, since ACE inhibitors are the first line of antihypertensive drugs so present study was undertaken with the aim to evaluate the possible effects of ACE inhibitor on lipid profile in albino rabbits.Methods: The study was conducted in the Department of Pharmacology and Therapeutics, GSVM Medical College, Kanpur. Rabbits were divided into 2 groups with 6 in each group. Rabbits of Group I was given Lisinopril in dose of 0.25mg/kg and of group II was given Perindopril in dose of 0.20mg/kg for a period of 6 weeks. Lipid profile estimation (Serum Total cholesterol, serum HDL, serum LDL, serum Triglycerides and serum VLDL) was done at day 0, 7, 21 and 45 respectively.Results: After analysis Rabbits of group-I (Lisinopril) showed 3.1% decrease in serum cholesterol level at 45th day (P<0.001). Serum HDL level increased by 6.4% and 14.3% at day 21 and 45 respectively (P<0.05). Increase in serum Triglyceride level was 2.6% at day 45 (P>0.05). Serum LDL level decreases by 4.4% and 8.6% at day 21 and 45 respectively (P<0.001). There was no significant change in Serum VLDL level. Rabbits of group- II (Perindopril) showed decreased total cholesterol levels by 2.6% (P<0.05). There was an increase in HDL level by 6.8 % at day 45(P<.05). Triglycerides and VLDL levels were not significantly altered while serum LDL level decreases by 6.7% at day 45 (P<0.01).Conclusions: From our study it was concluded that Lisinopril had a favourable effect on serum lipid profile by decreasing total cholesterol, increasing serum HDL level. It may increase triglycerides, decrease LDL. Perindopril increase serum HDL and decreases LDL, there is no significant change in cholesterol, TG and VLDL levels.


2019 ◽  
Vol 9 (2) ◽  
pp. e18-e18
Author(s):  
Milad Fooladgar ◽  
Saied Mardani ◽  
Leyla Hedayati Zafarghand

Introduction: Dysregulated lipid profile has been described in patients with chronic renal failure. Objectives: In the present study, we investigated the association of serum magnesium level with serum triglyceride and cholesterol levels in a group of hemodialysis individuals. Patients and Methods: This cross-sectional study was carried out on hemodialysis patients referred to the Hajar hospital of Shahrekord (2015). Patients who have been on hemodialysis for at least three months and had a stable condition for the last two months were recruited. Serum levels of magnesium, cholesterol, and triglyceride were measured, and the data was analyzed. Results: Of 52 patients, 61.5% were males. The mean age of the patients was 60.17 ± 48.70 (range; 13-78) years and the mean dialysis duration was 44.39 ± 05.52 months. Serum magnesium was inversely and insignificantly correlated with serum cholesterol and triglyceride levels. Serum magnesium was significantly associated with serum albumin and parathormone. Conclusion: We found non-significant and inverse correlations of serum magnesium with serum cholesterol and triglyceride levels. The association between serum magnesium and dyslipidemia is contradictory, and further studies are required to divulge the role of other contributing factors.


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