scholarly journals Morphofunctional peculiarities of tissue of oral cavity in chronic recurrent aphthous stomatitis with therapeutical correction

2016 ◽  
Vol 3 (3) ◽  
pp. 146-149
Author(s):  
Kovac I.V., Kravchenko L.I., Gargin V.V.
Keyword(s):  
Oral Cavity ◽  
Oral Mucosa ◽  
Soft Tissues ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Histological Investigation ◽  
Ozone Therapy ◽  
Experimental Animals ◽  
Methods Of Treatment ◽  
Β Carotene

Chronic recurrent aphthous stomatitis (CRAS) belongs to the group of chronic, inflammatory, ulcerative diseases of the oral mucosa. The aim of this study was to identify the morphofunctional peculiarities in chronic recurrent aphthous stomatitis with therapeutical correction in soft tissues of the oral cavity of experimental animals in the modeling of chronic recurrent aphthous stomatitis. We performed experimental investigation for study of the morpho-functional state of tissues of the oral mucosa in CRAS and formed three groups of animals (rabbits) with different methods of treatment. Histological investigation have been performed. Conclusion of our research is that correction of tissual changes in chronic recurrent aphthous stomatitis could be obtained with application of gel with β-carotene, α-tocopherol, a mixture of vegetable oils; with ozone therapy and their combination.Keywords: chronic recurrent aphthous stomatitis, histology, experiment. АннотацияКовач И.В., Кравченко Л.И., Гаргин В.В*.Морфофункциональные особенности тканей ротовой полости при хроническом рецидивирующем афтозном стоматите с терапевтической коррекциейХронический рецидивирующий афтозный стоматит относится к группе хронических, воспалительных, язвенных заболеваний слизистой оболочки полости рта. Целью данного исследования явилось выявление морфофункциональных особенностей мягких тканей ротовой полости экспериментальных животных при моделировании хронического рецидивирующего афтозного стоматита с терапевтической коррекцией. Мы моделировали хронический рецидивирующий афтозный стоматит и изучили морфо-функциональное состояние тканей слизистой оболочки полости рта сформировав три группы животных (кроликов) с различными методами лечения. Было проведено гистологическое исследование. Вывод наших исследований заключается в том, что коррекция тканевых изменений при хроническом рецидивирующем афтозном стоматите может быть получена при применении геля с бета-каротином, альфа-токоферолом, смесью растительных масел, кроме этого при озонотерапии и комбинации указанных методов.Ключевые слова: хронический рецидивирующий афтозный стоматит, гистология, эксперимент. АнотаціяКовач І.В., Кравченко Л.І., Гаргін В.В.*Морфофункціональні особливості тканин ротової порожнини при хронічному рецидивуючому афтозний стоматит з терапевтичної корекцією Хронічний рецидивний афтозний стоматит відноситься до групи хронічних, запальних, виразкових захворювань слизової оболонки порожнини рота. Метою даного дослідження було виявлення морфофункціональних особливостей м'яких тканин ротової порожнини експериментальних тварин при моделюванні хронічного рецидивуючого афтозного стоматиту з терапевтичної корекцією. Ми моделювали хронічний рецидивний афтозний стоматит і вивчали морфо-функціональний стан тканин слизової оболонки порожнини рота сформувавши три групи тварин (кроликів) з різними методами лікування. Було проведено гістологічне дослідження. Висновок наших досліджень полягає в тому, що корекція тканинних змін при хронічному рецидивуючому афтозному стоматит може бути отримана при застосуванні гелю з бета-каротином, альфа-токоферолом, сумішшю рослинних масел, крім цього при озонотерапії та комбінації вказаних методів.Ключові слова: хронічний рецидивуючий афтозний стоматит, гістологія, експеримент.

scholarly journals RECURRENT APHTHOUS STOMATITIS RELATED TO PSYCHOLOGICAL STRESS, FOOD ALLERGY AND GERD

2019 ◽  
Vol 6 ◽  
pp. 45
Author(s):  
Rina Kartika Sari ◽  
Diah Savitri Ernawati ◽  
Bagus Soebadi
Keyword(s):  
Food Allergy ◽  
Psychological Stress ◽  
Oral Mucosa ◽  
Recurrent Aphthous Stomatitis ◽  
Predisposing Factors ◽  
Aphthous Stomatitis ◽  
Cow Milk ◽  
Esophageal Mucosa ◽  
History Of ◽  
Multiple Ulcers

Background: Recurrent Aphthous Stomatitis (RAS) is inflammation in oral mucosa characterized by recurrent single or multiple ulcers that usually affected in non keratinized mucosa. Etiology RAS is unknown but psychological stress, allergy, and gastrointestinal disease can be predisposing factors Case Management: A 23rd years old complained recurrent oral ulcer with free ulcer period for 3-5 days. The patient had a history of food allergy, GERD and psychological stress. Intraoral examination showed recurrent multiple ulcers in variation site of the mouth. DASS 42 screening showed high stress and high anxiety. Skin Prick Test showed positive allergy to kapok, beef, chicken, cow milk, white egg, duck egg, shrimp, cob fish, milkfish, chocolate, and peanut. Ulcers treated with nonsteroid antiinflammation Aloe Vera gel and stress management by reading assignment method.Discussion: Psychological stress altered the immune system so oral mucosa prone to inflammation, and make the history of GERD getting worse. Stress causes cortisol secretion that changes the imbalance of proinflammatory and antiinflammatory cytokines. Oral mucosa becomes more susceptible to hypersensitivity. In addition, stress decreased oral and esophageal mucosa resistance to GERDConclusion: RAS triggered by psychological stress, allergy, and GERD. Treatment of RAS is by elimination predisposing factors to prevent recurrence.

scholarly journals Recurrent aphthous stomatitis (RAS) and exfoliative cheilitis in elderly psoriasis sufferer

2016 ◽  
Vol 1 (1) ◽  
pp. 74
Author(s):  
Siti Hardiyanti Nurhasanah ◽  
Astrid Palmasari ◽  
Dwi Setyaningtyas ◽  
Sujati Sujati ◽  
Okty Setyawati
Keyword(s):  
Oral Cavity ◽  
Laboratory Test ◽  
Recurrent Aphthous Stomatitis ◽  
Team Work ◽  
Aphthous Stomatitis ◽  
Elderly Male ◽  
Normal Limits ◽  
General Practioner ◽  
The Right ◽  
Genital Disease

<p>Recurrent Aphthous Stomatitis (RAS) is a disorder in the oral cavity, with a characterized symptom as ulceration, recurrent and very painfull. The etiology is idiopathic, with multifactorial predisposition. Exfoliative cheilitis is a persistent lesion on the lip, with a characterized cracking and desquamative, with crustae and inflammation. An elderly male (72 yrs) suffered with ulcer on his oral cavity, cracking lips and pain on both of his cheeks, skin, since 5 years ago. The pain is recurrent. On the clinical examination, there were some desquamation, both on the skin and vermilion border, whether on the inner lips (labial fold mucosa), there were ulcers with diameter about 1 cm. The laboratory test was within normal limits, except the LED was 40 mm/hour (n:&lt;15). The diagnosis was Recurrent Aphthous Stomatitis (RAS) for the ulcer and Exfoliative cheilitis for the cracking lips. The treatment he received was a gargle liquid, topical corticosteroid and supplement. The skin’s disorder was revered to the skin and genital disease department, for further management. As a dental general practioner, had to be very careful and familiar for every changes that may be occur both in the outer or inner oral cavity. Other disorder that need refferal, had to be done with team work, to the colleague from the right connection.</p>

scholarly journals GAMBARAN STOMATITIS AFTOSA REKUREN DAN STRES PADA NARAPIDANA DI LEMBAGA PEMASYARAKATAN KELAS II B BITUNG

e-GIGI ◽  
2014 ◽  
Vol 3 (1) ◽  
Author(s):  
Melky G. Junhar ◽  
Pieter L. Suling ◽  
Aurelia S. R. Supit
Keyword(s):  
Oral Cavity ◽  
Sampling Method ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Mild Stress ◽  
Severe Stress ◽  
Cross Sectional ◽  
Class Iib ◽  
As Stress ◽  
Moderate Stress

Abstract: Prisoners are individuals who have been convicted of crimes and were sentenced to prison so they lost their freedom. Lost of freedom can cause stress. Stress is the ability of a person to survive under pressure without causing disturbance. Recurrent aphthous stomatitis (RAS) is a manifestation in the oral cavity which is usually triggered by some predisposing factors such as stress. This study aimed to describe recurrent aphthous stomatitis and stress among prisoners in prison class IIB Bitung. This study was cross-sectional with total sampling method. All prisoners who had experienced recurrent aphtous stomatitis (RAS) while in prison class IIB Bitung. The results showed that among the 56 respondents there were 53 male respondents (94.64%) and 3 female respondents (5.36%); 19 (33.93%) got mild stress, 18 (32.14%) moderate stress, 16 (28.58%) severe stress, and 3 (5.35%) very severe stress.Keywords: prisoner, stress, recurrent aphthous stomatitis (RAS)Abstrak: Narapidana adalah individu yang telah terbukti melakukan tindak pidana dan kemudian oleh pengadilan dijatuhi hukuman atau pidana serta kehilangan kebebasan. Kehilangan kebebasan menimbulkan terjadinya stres pada narapidana. Stres merupakan kemampuan individu untuk bertahan dalam menghadapi berbagai tekanan tanpa mengakibatkan gangguan. Stomatitis aftosa rekuren (SAR) merupakan manifestasi yang timbul dalam rongga mulut yang biasanya dipicu oleh beberapa faktor predisposisi, salah satunya stres. Tujuan penelitian yaitu mengetahui gambaran stomatitis aftosa rekuren dan stres pada narapidana di Lembaga Pemasyarakatan (LP) Kelas IIB Bitung. Jenis penelitian ini menggunakan desain potong lintang. Semua narapidana yang pernah mengalami Stomatitis Aftosa Rekuren (SAR) saat berada di Lembaga Pemasyarakatan kelas II B Bitung. Hasil penelitian menunjukkan bahwa dari 56 responden terdapat 53 responden berjenis kelamin laki-laki (94,64%) dan terdapat 3 responden berjenis kelamin perempuan (5,36%). Hasil pengukuran stres menunjukkan bahwa dari 56 responden 19 responden (33,93%) mengalami tingkat stres ringan, 18 responden (32,14%) mengalami tingkat stres sedang, 16 responden (28,58%) mengalami tingkat stres berat dan 3 responden (5,35%) mengalami tingkat stres sangat berat.Kata kunci: narapidana, stres, stomatitis aftosa rekuren.

scholarly journals Oral Microbiota Composition and Antimicrobial Antibody Response in Patients with Recurrent Aphthous Stomatitis

2019 ◽  
Vol 7 (12) ◽  
pp. 636 ◽  
Author(s):  
Zuzana Stehlikova ◽  
Vojtech Tlaskal ◽  
Natalie Galanova ◽  
Radka Roubalova ◽  
Jakub Kreisinger ◽  
...  
Keyword(s):  
Oral Mucosa ◽  
Serum Levels ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Common Disease ◽  
Oral Microbiota ◽  
Healthy Controls ◽  
Alpha And Beta Diversity ◽  
Oral Site ◽  
Bacteria And Fungi

Recurrent aphthous stomatitis (RAS) is the most common disease of the oral mucosa, and it has been recently associated with bacterial and fungal dysbiosis. To study this link further, we investigated microbial shifts during RAS manifestation at an ulcer site, in its surroundings, and at an unaffected site, compared with healed mucosa in RAS patients and healthy controls. We sampled microbes from five distinct sites in the oral cavity. The one site with the most pronounced differences in microbial alpha and beta diversity between RAS patients and healthy controls was the lower labial mucosa. Detailed analysis of this particular oral site revealed strict association of the genus Selenomonas with healed mucosa of RAS patients, whereas the class Clostridia and genera Lachnoanaerobaculum, Cardiobacterium, Leptotrichia, and Fusobacterium were associated with the presence of an active ulcer. Furthermore, active ulcers were dominated by Malassezia, which were negatively correlated with Streptococcus and Haemophilus and positively correlated with Porphyromonas species. In addition, RAS patients showed increased serum levels of IgG against Mogibacterium timidum compared with healthy controls. Our study demonstrates that the composition of bacteria and fungi colonizing healthy oral mucosa is changed in active RAS ulcers, and that this alteration persists to some extent even after the ulcer is healed.

scholarly journals Penatalaksanaan stomatitis aftosa rekuren mayor dengan infeksi sekunder Management of major recurrent aphtous stomatitis accompanied by secondary infection

2011 ◽  
Vol 10 (1) ◽  
pp. 42
Author(s):  
Nurdiana Nurdiana ◽  
M. Jusri
Keyword(s):  
Immune Response ◽  
Oral Mucosa ◽  
Secondary Infection ◽  
Good Prognosis ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Proper Treatment ◽  
Local Immune Response

Recurrent aphthous stomatitis (RAS)is an ulcerative condition that affects the oral mucosa without evidence ofunderlying disorder. It’s characterized by the appearance of recurring round, shallow ulcerations surrounded byinflammation that mainly involves the nonkeratinized mucosa. The classification of SAR are minor, major, andherpetiform types. Although rare, secondary infection may occur. Treatment is directed to avoid local traumaticprecipitants, lessen the pain and duration of ulceration by suppressing the local immune response, and preventsecondary infection. The objective of this paper is to discuss the treatment of RAS with secondary infection, a caseof 24-year-old man with multiple large ulcers that did not heal for almost 4 weeks. The ulcers were diagnosed asmajor RAS with secondary infection, and treated with metronidazole and ciprofloxacin, healed in 2 weeks withscars. Although secondary infection will delay healing, but with proper treatment, major RAS has good prognosis.

scholarly journals The Local Immunity of the Oral Cavity in Women with Recurrent Aphthous Stomatitis Associated with Urogenital Infection

2019 ◽  
Vol 09 (01) ◽  
pp. 1-8
Author(s):  
Оlga А. Uspenskaya ◽  
Larisa N. Kazarina ◽  
Еlena А. Shevchenko ◽  
Josef Herbert
Keyword(s):  
Oral Cavity ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Local Immunity ◽  
Urogenital Infection

scholarly journals STOMATITIS APTHOSA REKUREN (SAR) MINOR MULTIPLE PRE MENSTRUASI (Laporan Kasus)

2014 ◽  
Vol 1 (2) ◽  
pp. 57
Author(s):  
Amelia Thantawi ◽  
Khairiati . ◽  
Mela Meri Nova ◽  
Sri Marlisa ◽  
Abu Bakar
Keyword(s):  
Menstrual Cycle ◽  
Case Management ◽  
Clinical Features ◽  
Soft Tissues ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Topical Steroids ◽  
Early Lesions ◽  
Trauma Case ◽  
Recurrent Ulcers

Recurrent aphthous stomatitis (RAS) is an inflammation of the soft tissues of the mouth that is characterized by recurrent ulcers. SAR is clinically divided into three types, ie recurrent aphthous stomatitis minor, major and herpetiform. Clinical features of minor types usually with a diameter of about 2-4 mm with yellow-gray base and surrounded by an erythematous halo, affects mainly the non-keratinized mobile mucosae such as lips and tongue, a few ulcers (1-5) or multiple at a time, minor ulcers usually heal within 10-14 days without scarring. Early lesions on the SAR is usually felt by people as burning, followed by extremely pain. The aetiology of RAS is unknown, but associated with a variety of predisposing such as menstrual cycle and trauma. Case management is topical steroids, topical antiseptic and vitamins C to relieve the symptoms and fasten healing.

scholarly journals Management of Recurrent Aphthous Stomatitis in a Patient with High Recurrence Frequency

2020 ◽  
Vol 4 (4) ◽  
pp. 102-108
Author(s):  
Sri Hernawati
Keyword(s):  
Female Patient ◽  
Buccal Mucosa ◽  
Soft Tissues ◽  
Aloe Vera ◽  
Recurrent Aphthous Stomatitis ◽  
Aphthous Stomatitis ◽  
Vitamin B ◽  
Dental Hospital ◽  
Recurrence Frequency ◽  
Multiple Ulcers

RAS (Recurrent Aphthous Stomatitis) is an inflammation of soft tissues of the oral cavity characterized by recurrent and painful ulcers. These lesions can be marked early on with a burning sensation, and when the wound has formed, the pain is getting worse. Occasional symptoms of precursors, paresthesia and hyperesthesia, are sometimes reported. Pain and discomfort arise along movement around the ulcer e.g. eating, talking and swallowing. Characteristics of RAS are usually single or multiple ulcers occurring recursively on the oral mucosa, round or oval in shape, clearly demarcated, with a grayish-yellow necrotic center and reddish edges. Lesions occur at young ages i.e. children and puberty, and may occur in adults as well. Ulcers usually last in 1 week or month. This disorder is classified into three categories according to size i.e. recurrent aphthous stomatitis minor, major and herpetiformis. The aim of this report is to show the management of cases of Recurrent Aphthous Stomatitis Minor on the left side of tongue, left buccal mucosa, and lower labial mucosa in female patient aged 19 years. A 19-year-old female patient came to the Dental Hospital of Jember University with complaints of thrush on the left side of her tongue, left buccal mucosa and lower labial mucosa, pain, and feeling disturbed due to the pain when eating, talking, and laughing. In this case, the diagnosis showed Recurrent Aphthous Minor Stomatitis on the left side of the tongue, left buccal mucosa, and lower labial mucosa. The therapy was using nonsteroidal anti-inflammatory mouthwash containing aloe Vera and hyaluronic acid as well as giving multivitamin of becomzet (vitamin B complex, A, C, E, and Zinc). Keywords: recurrent aphthous stomatitis; high recurrence

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